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RU2003137600A - Крем для лечения солнечных ожогов - Google Patents

Крем для лечения солнечных ожогов Download PDF

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Publication number
RU2003137600A
RU2003137600A RU2003137600/15A RU2003137600A RU2003137600A RU 2003137600 A RU2003137600 A RU 2003137600A RU 2003137600/15 A RU2003137600/15 A RU 2003137600/15A RU 2003137600 A RU2003137600 A RU 2003137600A RU 2003137600 A RU2003137600 A RU 2003137600A
Authority
RU
Russia
Prior art keywords
cream
lipoic acid
active ingredients
coenzyme
acetyl
Prior art date
Application number
RU2003137600/15A
Other languages
English (en)
Other versions
RU2313333C2 (ru
Inventor
Йохан АНДЕРССОН (SE)
Йохан АНДЕРССОН
Ульф СТАРЛАНДЕР (SE)
Ульф СТАРЛАНДЕР
Бьорн АНДЕРССОН (SE)
Бьорн АНДЕРССОН
Original Assignee
Макронова АБ (SE)
Макронова АБ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Макронова АБ (SE), Макронова АБ filed Critical Макронова АБ (SE)
Publication of RU2003137600A publication Critical patent/RU2003137600A/ru
Application granted granted Critical
Publication of RU2313333C2 publication Critical patent/RU2313333C2/ru

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/004Aftersun preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/385Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35Ketones, e.g. benzophenone
    • A61K8/355Quinones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4986Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with sulfur as the only hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66Enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)

Claims (4)

1. Крем для наружного лечения видимых солнечных повреждений, вызванных процессами, включающими в себя воздействие свободных радикалов, активные ингредиенты которого находятся в стабилизирующей основе для крема, отличающийся тем, что 0,5-7 мас.% D,L-α-липоевой кислоты, 0,05-0,5 мас.% кофермента Q-10 и 0,01-3 мас.% ацетил-L-карнитина гидрохлорида составляют эти активные ингредиенты.
2. Крем по п.1, отличающийся тем, что он содержит 5 мас.% D,L-α-липоевой кислоты, 0,3 мас.% кофермента Q-10 и 0,03 мас.% ацетил-L-карнитина гидрохлорида.
3. Крем по п.1, отличающийся тем, что он содержит 1 мас.% D,L-α-липоевой кислоты, 0,3% масс. кофермента Q-10 и 0,03% масс. ацетил-L-карнитина гидрохлорида.
4. Способ приготовления крема, содержащего D,L-a-липоевую кислоту, отличающийся тем, что перед смешиванием с остальными компонентами данного крема активный ингредиент, представляющий собой D,L-α-липоевую кислоту, растворяют в каприловом/каприновом триглицериде, после чего указанную смесь D,L-α-липоевой кислоты и каприлового/капринового триглицерида добавляют к основе для крема.
RU2003137600/15A 2001-07-02 2002-06-30 Крем для лечения кожи, поврежденной солнцем RU2313333C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0102380A SE0102380D0 (sv) 2001-07-02 2001-07-02 Kräm för behandling av åldersförändringar i huden hos människa
SE0102380-3 2001-07-02

Publications (2)

Publication Number Publication Date
RU2003137600A true RU2003137600A (ru) 2005-03-27
RU2313333C2 RU2313333C2 (ru) 2007-12-27

Family

ID=20284723

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2003137600/15A RU2313333C2 (ru) 2001-07-02 2002-06-30 Крем для лечения кожи, поврежденной солнцем

Country Status (20)

Country Link
US (2) US20050152856A2 (ru)
EP (1) EP1411889B1 (ru)
JP (1) JP2005507406A (ru)
KR (1) KR100885347B1 (ru)
CN (1) CN1713888B (ru)
AT (1) ATE349998T1 (ru)
AU (1) AU2002318699B2 (ru)
BR (1) BR0210760A (ru)
CA (1) CA2450726A1 (ru)
CY (1) CY1107600T1 (ru)
DE (1) DE60217356T2 (ru)
DK (1) DK1411889T3 (ru)
ES (1) ES2280554T3 (ru)
MX (1) MXPA03011509A (ru)
NO (1) NO20035715D0 (ru)
NZ (1) NZ530226A (ru)
PT (1) PT1411889E (ru)
RU (1) RU2313333C2 (ru)
SE (1) SE0102380D0 (ru)
WO (1) WO2003037291A1 (ru)

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WO2009145982A1 (en) * 2008-04-01 2009-12-03 Antipodean Pharmaceuticals, Inc. Compositions and methods for skin care
EP2271325A4 (en) 2008-04-11 2011-11-09 Cytotech Labs Llc METHODS AND USE OF INDUCING APOPTOSIS IN CANCER CELLS
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US10519504B2 (en) 2009-05-11 2019-12-31 Berg Llc Methods for treatment of oncological disorders using epimetabolic shifters, multidimensional intracellular molecules, or environmental influencers
US11400058B2 (en) 2010-03-12 2022-08-02 Berg Llc Intravenous formulations of coenzyme Q10 (CoQ10) and methods of use thereof
EP2694463B8 (en) 2011-04-04 2019-10-09 Berg LLC Treating central nervous system tumors with coenzyme q10
EA201490047A1 (ru) 2011-06-17 2014-08-29 Берг Ллк Ингаляционные фармацевтические композиции
EA032775B1 (ru) 2013-04-08 2019-07-31 Берг Ллк Способы лечения злокачественной опухоли с использованием комбинированной терапии с коферментом q10
WO2015035094A1 (en) 2013-09-04 2015-03-12 Berg Llc Methods of treatment of cancer by continuous infusion of coenzyme q10
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SE543528C2 (en) * 2019-04-04 2021-03-16 Medica Clinical Nord Sverige Ab Cream for treatment of skin injured by the sun
CN119950732A (zh) * 2023-11-09 2025-05-09 福州大学 一种纳米药物透皮递送系统及其制备方法和应用

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Also Published As

Publication number Publication date
WO2003037291A1 (en) 2003-05-08
DE60217356T2 (de) 2007-10-11
US20050152856A2 (en) 2005-07-14
US20040219114A1 (en) 2004-11-04
DE60217356D1 (de) 2007-02-15
BR0210760A (pt) 2004-07-20
KR20040030728A (ko) 2004-04-09
AU2002318699B2 (en) 2007-01-04
NZ530226A (en) 2005-08-26
WO2003037291A8 (en) 2004-05-13
ATE349998T1 (de) 2007-01-15
EP1411889A1 (en) 2004-04-28
MXPA03011509A (es) 2004-10-28
CY1107600T1 (el) 2013-03-13
PT1411889E (pt) 2007-04-30
RU2313333C2 (ru) 2007-12-27
US20070212431A1 (en) 2007-09-13
ES2280554T3 (es) 2007-09-16
JP2005507406A (ja) 2005-03-17
CA2450726A1 (en) 2003-05-08
CN1713888A (zh) 2005-12-28
DK1411889T3 (da) 2007-05-07
NO20035715D0 (no) 2003-12-19
SE0102380D0 (sv) 2001-07-02
EP1411889B1 (en) 2007-01-03
CN1713888B (zh) 2011-01-26
KR100885347B1 (ko) 2009-02-26

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Effective date: 20110701