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RU2003127031A - METHOD FOR IDENTIFICATION OF ANTI-EXPRESSIVE ANTIDEPRESSANT EFFECT - Google Patents

METHOD FOR IDENTIFICATION OF ANTI-EXPRESSIVE ANTIDEPRESSANT EFFECT Download PDF

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Publication number
RU2003127031A
RU2003127031A RU2003127031/15A RU2003127031A RU2003127031A RU 2003127031 A RU2003127031 A RU 2003127031A RU 2003127031/15 A RU2003127031/15 A RU 2003127031/15A RU 2003127031 A RU2003127031 A RU 2003127031A RU 2003127031 A RU2003127031 A RU 2003127031A
Authority
RU
Russia
Prior art keywords
antidepressant
expressive
identification
antidepressant effect
identified
Prior art date
Application number
RU2003127031/15A
Other languages
Russian (ru)
Other versions
RU2266538C2 (en
Inventor
Нина Павловна Ванчакова (RU)
Нина Павловна Ванчакова
Натали Николаевна Шестакова (RU)
Наталия Николаевна Шестакова
Ксени Валерьевна Рыбакова (RU)
Ксения Валерьевна Рыбакова
Original Assignee
Нина Павловна Ванчакова (RU)
Нина Павловна Ванчакова
Натали Николаевна Шестакова (RU)
Наталия Николаевна Шестакова
Ксени Валерьевна Рыбакова (RU)
Ксения Валерьевна Рыбакова
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Нина Павловна Ванчакова (RU), Нина Павловна Ванчакова, Натали Николаевна Шестакова (RU), Наталия Николаевна Шестакова, Ксени Валерьевна Рыбакова (RU), Ксения Валерьевна Рыбакова filed Critical Нина Павловна Ванчакова (RU)
Priority to RU2003127031/15A priority Critical patent/RU2266538C2/en
Publication of RU2003127031A publication Critical patent/RU2003127031A/en
Application granted granted Critical
Publication of RU2266538C2 publication Critical patent/RU2266538C2/en

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  • Investigating Or Analysing Biological Materials (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Claims (2)

1. Способ идентификации противозудного эффекта антидепрессанта с использованием компьютерной программы для расчета моделей химических структур, заключающийся в том, что осуществляют визуальный анализ всех устойчивых конформеров молекулы антидепрессанта и при обнаружении хотя бы одного устойчивого конформера, содержащего структуру из двух взаимоцентрированных ароматических колец, плоскости которых способны ориентироваться под углом 120° по отношению друг к другу, идентифицируют противозудный эффект антидепрессанта.1. A method for identifying the antipruritic effect of an antidepressant using a computer program for calculating models of chemical structures, which consists in performing a visual analysis of all stable conformers of the antidepressant molecule and upon detection of at least one stable conformer containing a structure of two mutually centered aromatic rings whose planes are capable of oriented at an angle of 120 ° relative to each other, the antipruritic effect of the antidepressant is identified. 2. Применение антидепрессанта, идентифицированного способом по п.1, для лечения зуда.2. The use of an antidepressant identified by the method according to claim 1, for the treatment of pruritus.
RU2003127031/15A 2003-08-27 2003-08-27 Method for identifying anti-itching effect of antidepressant RU2266538C2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU2003127031/15A RU2266538C2 (en) 2003-08-27 2003-08-27 Method for identifying anti-itching effect of antidepressant

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU2003127031/15A RU2266538C2 (en) 2003-08-27 2003-08-27 Method for identifying anti-itching effect of antidepressant

Publications (2)

Publication Number Publication Date
RU2003127031A true RU2003127031A (en) 2005-03-20
RU2266538C2 RU2266538C2 (en) 2005-12-20

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ID=35453883

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2003127031/15A RU2266538C2 (en) 2003-08-27 2003-08-27 Method for identifying anti-itching effect of antidepressant

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RU (1) RU2266538C2 (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL190755B1 (en) * 1999-01-07 2006-01-31 Pharmena Sp Z Oo Perpetration for use in therapy and prophylactics of dermatological diseases

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Publication number Publication date
RU2266538C2 (en) 2005-12-20

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Effective date: 20090828