RU2003122208A - Способ производства амидного соединения с применением микробного катализатора - Google Patents
Способ производства амидного соединения с применением микробного катализатора Download PDFInfo
- Publication number
- RU2003122208A RU2003122208A RU2003122208/13A RU2003122208A RU2003122208A RU 2003122208 A RU2003122208 A RU 2003122208A RU 2003122208/13 A RU2003122208/13 A RU 2003122208/13A RU 2003122208 A RU2003122208 A RU 2003122208A RU 2003122208 A RU2003122208 A RU 2003122208A
- Authority
- RU
- Russia
- Prior art keywords
- producing
- nitrile
- amide compound
- nitrile hydratase
- reaction temperature
- Prior art date
Links
- 230000000813 microbial effect Effects 0.000 title claims 5
- 239000003054 catalyst Substances 0.000 title claims 2
- 150000001875 compounds Chemical class 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- -1 amide compound Chemical class 0.000 claims 7
- 108010024026 Nitrile hydratase Proteins 0.000 claims 4
- 238000000034 method Methods 0.000 claims 4
- 230000000694 effects Effects 0.000 claims 3
- 241000590020 Achromobacter Species 0.000 claims 2
- 241000589291 Acinetobacter Species 0.000 claims 2
- 241000607534 Aeromonas Species 0.000 claims 2
- 241000193830 Bacillus <bacterium> Species 0.000 claims 2
- 241000588923 Citrobacter Species 0.000 claims 2
- 241000186216 Corynebacterium Species 0.000 claims 2
- 241000588914 Enterobacter Species 0.000 claims 2
- 241000588698 Erwinia Species 0.000 claims 2
- 241000588748 Klebsiella Species 0.000 claims 2
- 241000192041 Micrococcus Species 0.000 claims 2
- 241000187654 Nocardia Species 0.000 claims 2
- 241000589516 Pseudomonas Species 0.000 claims 2
- 241000589180 Rhizobium Species 0.000 claims 2
- 241000316848 Rhodococcus <scale insect> Species 0.000 claims 2
- 241000187747 Streptomyces Species 0.000 claims 2
- 241000589506 Xanthobacter Species 0.000 claims 2
- 244000005700 microbiome Species 0.000 claims 2
- FFNVQNRYTPFDDP-UHFFFAOYSA-N 2-cyanopyridine Chemical compound N#CC1=CC=CC=N1 FFNVQNRYTPFDDP-UHFFFAOYSA-N 0.000 claims 1
- NLHHRLWOUZZQLW-UHFFFAOYSA-N Acrylonitrile Chemical compound C=CC#N NLHHRLWOUZZQLW-UHFFFAOYSA-N 0.000 claims 1
- 241000589158 Agrobacterium Species 0.000 claims 1
- 241000187603 Pseudonocardia Species 0.000 claims 1
- 239000012736 aqueous medium Substances 0.000 claims 1
- 230000009261 transgenic effect Effects 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/10—Nitrogen as only ring hetero atom
- C12P17/12—Nitrogen as only ring hetero atom containing a six-membered hetero ring
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Claims (4)
1. Способ получения амидного соединения из нитрильного соединения с применением микробного катализатора, где микробные клетки, имеющие нитрилгидратазную активность 50 U или выше на мг сухих клеток при температуре реакции 10°С, приводят в контакт с нитрильным соединением в водной среде без иммобилизации захватом.
2. Способ получения амидного соединения по п.1, где микробные клетки, имеющие нитрилгидратазную активность 50 U или выше на мг сухих клеток при температуре реакции 10°С, являются по меньшей мере одними из членов группы, состоящей из родов Nocardia, Corynebacterium, Bacillus, Pseudomonas, Micrococcus, Rhodococcus, Acinetobacter, Xanthobacter, Streptomyces, Rhizobium, Klebsiella, Enterobacter, Erwinia, Aeromonas, Citrobacter, Achromobacter, Agrobacterium и Pseudonocardia.
3. Способ получения амидного соединения по п.1, где микробные клетки, имеющие нитрилгидратазную активность 50 U или выше на мг сухих клеток при температуре реакции 10°С, являются трансгенными микроорганизмами, которые экспрессируют ген нитрилгидратазы по меньшей мере одного микроорганизма, выбранного из группы, состоящей из родов Nocardia, Corynebacterium, Bacillus, Pseudomonas, Micrococcus, Rhodococcus, Acinetobacter, Xanthobacter, Streptomyces, Rhizobium, Klebsiella, Enterobacter, Erwinia, Aeromonas, Citrobacter, Achromobacter, Agrobacterium и Pseudonocardia.
4. Способ получения амидного соединения по любому из пп.1 - 3, где нитрильным соединением является акрилонитрил или цианопиридин.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000-387537 | 2000-12-20 | ||
| JP2000387537 | 2000-12-20 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2003122208A true RU2003122208A (ru) | 2005-01-20 |
| RU2288270C2 RU2288270C2 (ru) | 2006-11-27 |
Family
ID=18854447
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2003122208/13A RU2288270C2 (ru) | 2000-12-20 | 2001-12-19 | Способ производства амидного соединения с применением микробного катализатора |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7749739B2 (ru) |
| EP (1) | EP1352965B1 (ru) |
| JP (1) | JP4708677B2 (ru) |
| KR (1) | KR100547080B1 (ru) |
| CN (1) | CN1296487C (ru) |
| DE (1) | DE60133130T2 (ru) |
| IN (1) | IN209344B (ru) |
| RU (1) | RU2288270C2 (ru) |
| WO (1) | WO2002050297A1 (ru) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1352865B1 (en) * | 2002-04-12 | 2011-09-28 | Kabushiki Kaisha Toshiba | Sheet collection apparatus |
| US20070027294A1 (en) * | 2003-04-10 | 2007-02-01 | Dia-Nitrix Co., Ltd. | Process for producing high-quality acrylamide polymer with enzyme |
| DK1689875T3 (da) * | 2003-12-02 | 2010-02-01 | Ciba Spec Chem Water Treat Ltd | Fremstilling af amider |
| ATE532859T1 (de) * | 2003-12-02 | 2011-11-15 | Ciba Spec Chem Water Treat Ltd | Stamm von rhodococcus rhodochrous ncimb 41164 sowie dessen verwendung als nitrilhydrataseproduzent |
| GB0327901D0 (en) | 2003-12-02 | 2004-01-07 | Ciba Spec Chem Water Treat Ltd | Process for producing polymers |
| GB0416101D0 (en) * | 2004-07-19 | 2004-08-18 | Ciba Spec Chem Water Treat Ltd | Process for preparing monomers and polymers thereof |
| JP2006187257A (ja) * | 2005-01-07 | 2006-07-20 | Daiyanitorikkusu Kk | アミド化合物の製造方法およびアクリルアミド系ポリマー |
| KR20110038183A (ko) | 2005-10-07 | 2011-04-13 | 미쓰이 가가쿠 가부시키가이샤 | 아미드 화합물의 제조방법 |
| AU2011239258B2 (en) * | 2005-10-07 | 2012-09-27 | Mitsui Chemicals, Inc. | Method for producing amide compound |
| JP5630017B2 (ja) * | 2008-03-14 | 2014-11-26 | 三菱レイヨン株式会社 | アミド化合物の製造方法 |
| EP2518154B1 (en) * | 2009-12-25 | 2019-08-14 | Mitsubishi Chemical Corporation | Method for producing acrylamide using microbial catalyst |
| WO2011138966A1 (ja) * | 2010-05-06 | 2011-11-10 | ダイヤニトリックス株式会社 | 微生物触媒を用いたアクリルアミドの製造方法 |
| US9057084B2 (en) | 2011-05-19 | 2015-06-16 | Mitsubishi Rayon Co., Ltd. | Method for producing aqueous acrylamide solution |
| AU2012256709B2 (en) * | 2011-05-19 | 2016-07-07 | Mitsubishi Chemical Corporation | Method for producing acrylamide aqueous solution |
| BR112015013264B1 (pt) | 2012-12-10 | 2021-12-14 | Mitsubishi Chemical Corporation | Método para produzir acrilamida |
| US10655152B2 (en) | 2014-09-30 | 2020-05-19 | Solenis Technologies, L.P. | Method for producing an amide |
| CN105316263A (zh) * | 2015-11-25 | 2016-02-10 | 沈阳化工研究院有限公司 | 一种氰类化合物降解菌及其应用 |
| CN110157751A (zh) * | 2019-06-05 | 2019-08-23 | 英德市云超聚合材料有限公司 | 一种低电导率酰胺化合物水溶液的合成方法 |
| CN112626141B (zh) * | 2020-11-16 | 2022-12-06 | 广东宝莫生物化工有限公司 | 一种丙烯酰胺溶液的生产方法 |
| CN115216465A (zh) * | 2022-08-15 | 2022-10-21 | 武汉宏择一碳环保科技有限公司 | 一种基于膜分离工艺的丙烯酰胺制备方法 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2294999A1 (fr) * | 1974-12-18 | 1976-07-16 | Anvar | Procede de preparation d'amides par hydrolyse biologique |
| GB2018240B (en) | 1978-03-29 | 1982-12-22 | Nitto Chemical Industry Co Ltd | Process for producing acrylamide or methacrylamide utilizing microoganisms |
| JPS5937951B2 (ja) | 1981-11-18 | 1984-09-12 | 秀明 山田 | アミドの生物学的製造法 |
| JPS61162193A (ja) | 1985-01-08 | 1986-07-22 | Nitto Chem Ind Co Ltd | 微生物によるアミド類の製造法 |
| JPS61162194A (ja) * | 1985-01-11 | 1986-07-22 | Nitto Chem Ind Co Ltd | 微生物によるアミド類の製造法 |
| JPH0740948B2 (ja) | 1985-06-04 | 1995-05-10 | 旭化成工業株式会社 | アミドの微生物学的製造法 |
| MX169933B (es) * | 1987-09-18 | 1993-08-02 | Hideaki Yamada | Procedimiento para la produccion biologica de amidas |
| JPH0822221B2 (ja) * | 1988-12-28 | 1996-03-06 | 日東化学工業株式会社 | シュードモナス属細菌の培養法 |
| JP2907479B2 (ja) | 1990-02-28 | 1999-06-21 | 輝彦 別府 | ニトリルヒドラターゼ活性を有するポリペプチドをコードする遺伝子ｄｎａ、これを含有する形質転換体及びアミド類の製造法 |
| AU627648B2 (en) * | 1990-02-28 | 1992-08-27 | Teruhiko Beppu | Dna fragment encoding a polypeptide having nitrile hydratase activity, a transformant containing the gene and a process for the production of amides using the transformant |
| DE69231939T2 (de) * | 1991-03-04 | 2002-04-04 | Teruhiko Beppu | Hybrid-Plasmid-Vektoren, die für Nitril-abbauende Enzyme kodierende Gene enthalten und Verfahren zur Herstellung von Amiden und Säuren |
| AU2077392A (en) | 1991-08-05 | 1993-04-29 | Mitsubishi Kasei Corporation | Process for preparing amides |
| JPH06225780A (ja) | 1993-02-05 | 1994-08-16 | Mitsui Toatsu Chem Inc | 微生物によるアミド類の製造法 |
| RU2053300C1 (ru) * | 1993-12-17 | 1996-01-27 | Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов | Штамм бактерий rhodococcus rhodochrous - продуцент нитрилгидратазы |
| GB9506389D0 (en) * | 1995-03-29 | 1995-05-17 | King S College London | Catalyst and process for preparing amides |
| JP3531997B2 (ja) | 1995-03-29 | 2004-05-31 | 三井化学株式会社 | 形質転換体を用いたアミド化合物の製造法 |
| RU2077588C1 (ru) * | 1996-01-16 | 1997-04-20 | Государственное унитарное предприятие Саратовский научно-исследовательский институт биокатализа | Способ получения акриламида |
| CN1243825C (zh) | 1996-02-14 | 2006-03-01 | 三井化学株式会社 | 新型腈水合酶 |
| US5866379A (en) * | 1997-01-28 | 1999-02-02 | Novus International | Enzymatic conversion of α-hydroxynitriles to the corresponding .alpha. |
-
2001
- 2001-12-19 KR KR20037008207A patent/KR100547080B1/ko not_active Expired - Lifetime
- 2001-12-19 US US10/450,532 patent/US7749739B2/en not_active Expired - Lifetime
- 2001-12-19 IN IN1050CH2003 patent/IN209344B/en unknown
- 2001-12-19 RU RU2003122208/13A patent/RU2288270C2/ru active
- 2001-12-19 CN CNB018220312A patent/CN1296487C/zh not_active Ceased
- 2001-12-19 DE DE60133130T patent/DE60133130T2/de not_active Expired - Lifetime
- 2001-12-19 JP JP2002551176A patent/JP4708677B2/ja not_active Expired - Lifetime
- 2001-12-19 WO PCT/JP2001/011149 patent/WO2002050297A1/ja not_active Ceased
- 2001-12-19 EP EP01271129A patent/EP1352965B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| KR20030066720A (ko) | 2003-08-09 |
| IN2003CH01050A (ru) | 2005-04-22 |
| RU2288270C2 (ru) | 2006-11-27 |
| EP1352965A1 (en) | 2003-10-15 |
| US20040048348A1 (en) | 2004-03-11 |
| DE60133130D1 (de) | 2008-04-17 |
| CN1486370A (zh) | 2004-03-31 |
| IN209344B (ru) | 2007-09-21 |
| EP1352965A4 (en) | 2004-03-31 |
| EP1352965B1 (en) | 2008-03-05 |
| WO2002050297A1 (fr) | 2002-06-27 |
| JPWO2002050297A1 (ja) | 2004-04-22 |
| DE60133130T2 (de) | 2009-02-26 |
| KR100547080B1 (ko) | 2006-01-31 |
| CN1296487C (zh) | 2007-01-24 |
| JP4708677B2 (ja) | 2011-06-22 |
| US7749739B2 (en) | 2010-07-06 |
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| PD4A | Correction of name of patent owner | ||
| PC43 | Official registration of the transfer of the exclusive right without contract for inventions |
Effective date: 20180523 |
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| PD4A | Correction of name of patent owner |