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RU2002128176A - METHOD FOR EVALUATING THE INFLAMMATORY ACTIVITY OF SYNOVIAL LIQUID IN DISEASES OF LARGE JOINTS - Google Patents

METHOD FOR EVALUATING THE INFLAMMATORY ACTIVITY OF SYNOVIAL LIQUID IN DISEASES OF LARGE JOINTS

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Publication number
RU2002128176A
RU2002128176A RU2002128176/14A RU2002128176A RU2002128176A RU 2002128176 A RU2002128176 A RU 2002128176A RU 2002128176/14 A RU2002128176/14 A RU 2002128176/14A RU 2002128176 A RU2002128176 A RU 2002128176A RU 2002128176 A RU2002128176 A RU 2002128176A
Authority
RU
Russia
Prior art keywords
chemiluminescent
diseases
protein
response
imp
Prior art date
Application number
RU2002128176/14A
Other languages
Russian (ru)
Other versions
RU2229717C1 (en
Inventor
Сергей Олегович Давыдов
Дондок Дамдинович Цырендоржиев
Original Assignee
Государственное образовательное учреждение Читинская государственная медицинская академия
Filing date
Publication date
Application filed by Государственное образовательное учреждение Читинская государственная медицинская академия filed Critical Государственное образовательное учреждение Читинская государственная медицинская академия
Priority to RU2002128176/14A priority Critical patent/RU2229717C1/en
Priority claimed from RU2002128176/14A external-priority patent/RU2229717C1/en
Publication of RU2002128176A publication Critical patent/RU2002128176A/en
Application granted granted Critical
Publication of RU2229717C1 publication Critical patent/RU2229717C1/en

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Claims (1)

Способ оценки активности воспалительного процесса при заболеваниях крупных суставов путем хемилюминесцентного исследования, отличающийся тем, что определяют способность синовиальной жидкости модулировать кислород-зависимый окислительный метаболизм интактных нейтрофилов хемилюминесценцией, рассчитывают индекс хемилюминесцентного ответа по формулеA method for assessing the activity of the inflammatory process in diseases of large joints by chemiluminescent research, characterized in that the ability of the synovial fluid to modulate the oxygen-dependent oxidative metabolism of intact neutrophils by chemiluminescence is determined, and the index of the chemiluminescent response is calculated by the formula
Figure 00000001
Figure 00000001
 где ИХЛ - индекс хемилюминесцентного ответа (имп/Нф/г белка);where AND CL is the index of the chemiluminescent response (imp / Nf / g protein); Iсж - количество импульсов хемилюминесцентного ответа нейтрофилов при добавлении тестируемой внутрисуставной жидкости;I cg is the number of impulses of the chemiluminescent neutrophil response upon addition of the test intraarticular fluid; IбезСЖ - количество импульсов хемилюминесцентного ответа нейтрофилов без добавления внутрисуставной жидкости;I without coolant - the number of pulses of the chemiluminescent response of neutrophils without the addition of intraarticular fluid; N - число нейтрофилов доноров;N is the number of neutrophils of donors; Р - содержание белка (г/л) в синовиальной жидкости и при значении ИХЛ равном 0,7-1,5 имп/Нф/г белка диагностируют умеренную степень провоспалительной активности синовиальной жидкости, а при значении Ихл выше 1,5 имп/Нф/г белка - тяжелую степень воспалительного процесса в суставе.P is the protein content (g / l) in the synovial fluid and when the CL value is 0.7-1.5 imp / Nf / g of protein, a moderate degree of pro-inflammatory activity of the synovial fluid is diagnosed, and when the value of CL is higher than 1.5 imp / Nf / g protein - a severe inflammatory process in the joint.
RU2002128176/14A 2002-10-21 2002-10-21 Method for evaluating proinflammatory activity of synovia at diseases of large articulations RU2229717C1 (en)

Priority Applications (1)

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RU2002128176/14A RU2229717C1 (en) 2002-10-21 2002-10-21 Method for evaluating proinflammatory activity of synovia at diseases of large articulations

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Application Number Priority Date Filing Date Title
RU2002128176/14A RU2229717C1 (en) 2002-10-21 2002-10-21 Method for evaluating proinflammatory activity of synovia at diseases of large articulations

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RU2002128176A true RU2002128176A (en) 2004-04-27
RU2229717C1 RU2229717C1 (en) 2004-05-27

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2429476C1 (en) * 2010-04-22 2011-09-20 Государственное учреждение Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского (ГУ МОНИКИ им. М.Ф. Владимирского) Diagnostic technique for arthrosis
RU2533216C1 (en) * 2013-03-27 2014-11-20 Эдуард Борисович Абдулганиев Method of determining degree of inflammatory process expression in case of knee joint osteoarthrosis
RU2749784C1 (en) * 2020-10-12 2021-06-16 Государственное бюджетное учреждение здравоохранения Свердловской области "Центр специализированных видов медицинской помощи "Уральский институт травматологии и ортопедии имени В.Д. Чаклина" (ГБУЗ СО "ЦСВМП "УИТО им. В.Д. Чаклина") Method for diagnosing post-traumatic hemarthrosis

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RU2007721C1 (en) * 1991-06-25 1994-02-15 Саратовский научно-исследовательский институт травматологии и ортопедии Method of estimation of severity degree at knee joint meniscus rheumatic destruction
RU2101703C1 (en) * 1996-05-29 1998-01-10 Саратовский научно-исследовательский институт травматологии и ортопедии Method for detecting the cases of inflammatory process activity in rheumatoid arthritis patients
RU2159434C1 (en) * 1999-10-18 2000-11-20 Государственное федеральное учреждение науки Уральский научно-исследовательский институт травматологии и ортопедии Method for determining the nature of intra-articular inflammation

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