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RU2002117074A - A method of obtaining dry forms of a complex drug probiotic - Google Patents

A method of obtaining dry forms of a complex drug probiotic Download PDF

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Publication number
RU2002117074A
RU2002117074A RU2002117074/15A RU2002117074A RU2002117074A RU 2002117074 A RU2002117074 A RU 2002117074A RU 2002117074/15 A RU2002117074/15 A RU 2002117074/15A RU 2002117074 A RU2002117074 A RU 2002117074A RU 2002117074 A RU2002117074 A RU 2002117074A
Authority
RU
Russia
Prior art keywords
biomass
sorbent
stabilizer
dried
excipients
Prior art date
Application number
RU2002117074/15A
Other languages
Russian (ru)
Inventor
Махамат Махаматулловна Алсынбаева
Фанил Абузаровна Байгузина
Фаниля Абузаровна Байгузина
Валерий Федорович Кулагин
Тать на Николаевна Кузнецова
Татьяна Николаевна Кузнецова
Original Assignee
Махамат Махаматулловна Алсынбаева
Фанил Абузаровна Байгузина
Фаниля Абузаровна Байгузина
Валерий Федорович Кулагин
Тать на Николаевна Кузнецова
Татьяна Николаевна Кузнецова
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Махамат Махаматулловна Алсынбаева, Фанил Абузаровна Байгузина, Фаниля Абузаровна Байгузина, Валерий Федорович Кулагин, Тать на Николаевна Кузнецова, Татьяна Николаевна Кузнецова filed Critical Махамат Махаматулловна Алсынбаева
Priority to RU2002117074/15A priority Critical patent/RU2002117074A/en
Publication of RU2002117074A publication Critical patent/RU2002117074A/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Claims (5)

1. Способ получения комплексного лечебно-профилактического препарата, включающий основу, микробную массу живых бактерий-эубиотиков и стабилизатор, отличающийся тем, что он дополнительно содержит антагонистически активный штамм бактерий Bacillus subtilis 11В ВКМ В-2218Д.1. A method of obtaining a comprehensive therapeutic and prophylactic drug, comprising a base, a microbial mass of live eubiotics and a stabilizer, characterized in that it further comprises an antagonistically active bacterial strain Bacillus subtilis 11B VKM B-2218D. 2. Способ по п.1, отличающийся тем, что при получении твердой формы препарата в качестве сорбента для биомассы используют активированный уголь, карболонг, лактулозу, ацетилфталилцеллюлозу или гель фосфата алюминия, и после смешивания биомассы с сорбентом, полученные микрогранулы сушат методом вакуумной сушки.2. The method according to claim 1, characterized in that when preparing the solid form of the preparation, activated carbon, carbolong, lactulose, acetylphthalyl cellulose or aluminum phosphate gel are used as a sorbent for biomass, and after mixing the biomass with the sorbent, the obtained microgranules are dried by vacuum drying. 3. Способ по п.1, отличающийся тем, что для получения таблеток биомассу и вспомогательные вещества берут в соотношении 2:1-3:1.3. The method according to claim 1, characterized in that to obtain tablets the biomass and excipients are taken in a ratio of 2: 1-3: 1. 4. Способ по пп.1 и 3, отличающийся тем, что в качестве вспомогательных веществ используют стеарат кальция, тальк и (или) крахмал и (или) аэросил, глюкозу, сухое молоко и (или) метилцеллюлозу.4. The method according to claims 1 and 3, characterized in that as excipients use calcium stearate, talc and (or) starch and (or) aerosil, glucose, milk powder and (or) methyl cellulose. 5. Способ по п.1, отличающийся тем, что при получении капсул к биомассе добавляют стабилизатор и глюконат кальция в количестве 1-10 мас.%, высушивают и заключают в капсулы.5. The method according to claim 1, characterized in that when receiving the capsules, the stabilizer and calcium gluconate are added to the biomass in an amount of 1-10 wt.%, Dried and encapsulated.
RU2002117074/15A 2002-06-28 2002-06-28 A method of obtaining dry forms of a complex drug probiotic RU2002117074A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU2002117074/15A RU2002117074A (en) 2002-06-28 2002-06-28 A method of obtaining dry forms of a complex drug probiotic

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU2002117074/15A RU2002117074A (en) 2002-06-28 2002-06-28 A method of obtaining dry forms of a complex drug probiotic

Publications (1)

Publication Number Publication Date
RU2002117074A true RU2002117074A (en) 2004-02-27

Family

ID=36116878

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2002117074/15A RU2002117074A (en) 2002-06-28 2002-06-28 A method of obtaining dry forms of a complex drug probiotic

Country Status (1)

Country Link
RU (1) RU2002117074A (en)

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Legal Events

Date Code Title Description
FA93 Acknowledgement of application withdrawn (no request for examination)

Effective date: 20060209