PT996429E - Solucoes e dispersoes no estado solido de farmacosfracamente soluveis em agua - Google Patents
Solucoes e dispersoes no estado solido de farmacosfracamente soluveis em aguaInfo
- Publication number
- PT996429E PT996429E PT98955458T PT98955458T PT996429E PT 996429 E PT996429 E PT 996429E PT 98955458 T PT98955458 T PT 98955458T PT 98955458 T PT98955458 T PT 98955458T PT 996429 E PT996429 E PT 996429E
- Authority
- PT
- Portugal
- Prior art keywords
- pharmacosfully
- soluable
- disperses
- solutions
- water
- Prior art date
Links
- 239000007787 solid Substances 0.000 title 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 2
- 229920003171 Poly (ethylene oxide) Polymers 0.000 abstract 1
- 229920001400 block copolymer Polymers 0.000 abstract 1
- 125000005456 glyceride group Chemical group 0.000 abstract 1
- 229940124531 pharmaceutical excipient Drugs 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6333897P | 1997-10-27 | 1997-10-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT996429E true PT996429E (pt) | 2003-06-30 |
Family
ID=22048528
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT98955458T PT996429E (pt) | 1997-10-27 | 1998-10-15 | Solucoes e dispersoes no estado solido de farmacosfracamente soluveis em agua |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0996429B1 (pt) |
| JP (1) | JP2001520984A (pt) |
| CN (1) | CN1190187C (pt) |
| AT (1) | ATE232087T1 (pt) |
| DE (1) | DE69811233T2 (pt) |
| DK (1) | DK0996429T3 (pt) |
| ES (1) | ES2191977T3 (pt) |
| NO (1) | NO329755B1 (pt) |
| PT (1) | PT996429E (pt) |
| WO (1) | WO1999021534A1 (pt) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2775597B1 (fr) * | 1998-03-04 | 2001-04-20 | Gattefosse Ets Sa | Pellet administrable par voie orale apte a ameliorer la biodisponibilite de la substance active, procede de fabrication |
| JP2002517418A (ja) * | 1998-06-05 | 2002-06-18 | フォーブス メディ−テック インコーポレーテッド | 高められた溶解性および分散性を有するフィトステロールおよび／またはフィトスタノ−ルよりなる組成物 |
| US20030166525A1 (en) | 1998-07-23 | 2003-09-04 | Hoffmann James Arthur | FSH Formulation |
| SE9901667D0 (sv) * | 1999-05-07 | 1999-05-07 | Astra Ab | Method and device for forming particles |
| SE9902742D0 (sv) * | 1999-07-20 | 1999-07-20 | Astra Ab | New pharmaceutical formultion |
| US20010036479A1 (en) * | 2000-01-14 | 2001-11-01 | Gillian Cave | Glyburide composition |
| ITMI20011337A1 (it) * | 2001-06-26 | 2002-12-26 | Farmatron Ltd | Composizioni farmaceutiche orali a rilascio modificato del principio attivo |
| ITMI20011338A1 (it) * | 2001-06-26 | 2002-12-26 | Farmatron Ltd | Composizioni farmaceutiche orali a rilascio immediato del principio attivo |
| RU2330642C2 (ru) * | 2001-07-06 | 2008-08-10 | Лайфсайкл Фарма А/С | Регулируемая агломерация |
| IS6633A (is) * | 2002-11-22 | 2004-05-23 | Omega Farma Ehf. | Samsetningar af fínasteríð töflum |
| CN1310648C (zh) * | 2002-12-13 | 2007-04-18 | 佳高泰克有限公司 | 局部纳米颗粒螺甾内酯制剂 |
| AU2004212976A1 (en) * | 2003-02-19 | 2004-09-02 | Biovail Laboratories Inc. | Rapid absorption selective 5-HT agonist formulations |
| ME00217B (me) | 2003-04-02 | 2011-02-10 | Ares Trading Sa | TEČNE FARMACEUTSKE FORMULACIJE FSH i LH ZAJEDNO SA NEJONSKIM SURFAKTANTOM |
| SI1638595T1 (sl) | 2003-06-20 | 2013-04-30 | Ares Trading S.A. | Liofilizirane formulacije fsh/lh |
| CA2545919A1 (en) * | 2003-11-13 | 2005-06-02 | Alza Corporation | Melt blend dispersions comprising a low water solubility drug and an ethylene oxide-propylene oxide block copolymer |
| JP2007517016A (ja) | 2003-12-31 | 2007-06-28 | ファイザー・プロダクツ・インク | 低溶解性薬剤及びポロキサマーの固体組成物 |
| TW200616681A (en) * | 2004-10-05 | 2006-06-01 | Recordati Ireland Ltd | Lercanidipine capsules |
| EA011614B1 (ru) * | 2004-11-17 | 2009-04-28 | Арес Трейдинг С.А. | Препараты бензотиазола и их применение |
| EP1690528A1 (de) * | 2005-02-11 | 2006-08-16 | Abbott GmbH & Co. KG | Herstellung von Dosierungsformen mit einer festen Dispersion eines mikrokristallinen Wirkstoffs |
| ES2277767B1 (es) * | 2005-11-04 | 2008-04-01 | Simbec Iberica, S.L. | Formas orales solidas de ebastina. |
| EP1962808B1 (en) * | 2005-12-14 | 2010-09-29 | F. Hoffmann-La Roche AG | Hcv prodrug formulation |
| PT2054040E (pt) * | 2006-08-16 | 2011-06-30 | Novartis Ag | Método para produzir dispersões sólidas de compostos terapêuticos altamente cristalinos |
| EP1972336A1 (en) * | 2007-03-19 | 2008-09-24 | LEK Pharmaceuticals D.D. | Hot-melt micropellets |
| WO2010143199A1 (en) * | 2009-06-11 | 2010-12-16 | Suven Nishtaa Pharma Private Limited | Solid lipid dispersion for aqueous solubility enhancement of poorly water soluble drugs |
| EP2510924B1 (en) * | 2009-12-08 | 2014-10-08 | IL Hwa Co., Ltd | SOLID DISPERSIONS CONTAINING 20-O-ß-D-GLUCOPYRANOSYL-20(S)-PROTOPANAXADIOL |
| US10695431B2 (en) | 2010-10-29 | 2020-06-30 | Infirst Healthcare Limited | Solid solution compositions and use in cardiovascular disease |
| US9504664B2 (en) | 2010-10-29 | 2016-11-29 | Infirst Healthcare Limited | Compositions and methods for treating severe pain |
| US9308213B2 (en) | 2010-10-29 | 2016-04-12 | Infirst Healthcare Limited | Solid solution compositions and use in chronic inflammation |
| US11202831B2 (en) | 2010-10-29 | 2021-12-21 | Infirst Healthcare Limited | Solid solution compositions and use in cardiovascular disease |
| US9271950B2 (en) | 2010-10-29 | 2016-03-01 | Infirst Healthcare Limited | Compositions for treating chronic inflammation and inflammatory diseases |
| US9744132B2 (en) | 2010-10-29 | 2017-08-29 | Infirst Healthcare Limited | Solid solution compositions and use in chronic inflammation |
| US10695432B2 (en) | 2010-10-29 | 2020-06-30 | Infirst Healthcare Limited | Solid solution compositions and use in severe pain |
| US11224659B2 (en) | 2010-10-29 | 2022-01-18 | Infirst Healthcare Limited | Solid solution compositions and use in severe pain |
| US11730709B2 (en) | 2010-10-29 | 2023-08-22 | Infirst Healthcare Limited | Compositions and methods for treating severe pain |
| US8895536B2 (en) | 2010-10-29 | 2014-11-25 | Infirst Healthcare Ltd. | Compositions and methods for treating chronic inflammation and inflammatory diseases |
| JP5902188B2 (ja) | 2010-11-01 | 2016-04-13 | メリンタ セラピューティクス，インコーポレイテッド | 薬学的組成物 |
| EP2455068A1 (en) * | 2010-11-09 | 2012-05-23 | F. Hoffmann-La Roche AG | Pharmaceutical composition for treating HCV infections |
| KR102373259B1 (ko) * | 2012-05-03 | 2022-03-17 | 칼라 파마슈티컬스, 인크. | 개선된 점막 수송을 나타내는 제약 나노입자 |
| DE102012105512A1 (de) * | 2012-06-25 | 2014-04-24 | Hennig Arzneimittel Gmbh & Co. Kg | Arzneiform zur verlängerten Freisetzung von Wirkstoffen |
| WO2014176389A1 (en) | 2013-04-24 | 2014-10-30 | Temple University - Of The Commonwealth System Of Higher Education | Solid dosage form containing arabinogalactan |
| CA2914841C (en) * | 2013-08-01 | 2021-11-02 | Mw Encap Limited | Compositions and preparation methods of low melting ionic salts of poorly-water soluble drugs |
| ES2863500T3 (es) | 2015-04-10 | 2021-10-11 | Capsugel Belgium Nv | Formulaciones lipídicas de acetato de abiraterona |
| EP3492070A1 (en) * | 2017-11-30 | 2019-06-05 | BIT Pharma GmbH | Process and device for preparing a solid dispersion |
| CN114025744B (zh) * | 2019-04-08 | 2023-10-31 | 北京科信必成医药科技发展有限公司 | 改善药物物质溶解的方法及其产品 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8524421D0 (en) * | 1985-10-03 | 1985-11-06 | Boots Co Plc | Therapeutic agents |
| JPS62120315A (ja) * | 1985-11-20 | 1987-06-01 | Shin Etsu Chem Co Ltd | 経口投与型徐放性錠剤の製造方法 |
| JPH05255125A (ja) * | 1992-02-29 | 1993-10-05 | Upjohn Co:The | 徐放性製剤およびその製法 |
| JPH06316517A (ja) * | 1993-02-22 | 1994-11-15 | Grelan Pharmaceut Co Ltd | 放出制御製剤 |
| US5487887A (en) * | 1993-10-28 | 1996-01-30 | Bristol-Myers Squibb Company | Clear antiperspirant roll-on compositions |
| US5545628A (en) * | 1995-01-10 | 1996-08-13 | Galephar P.R. Inc. | Pharmaceutical composition containing fenofibrate |
| JPH08268878A (ja) * | 1995-03-06 | 1996-10-15 | Yoshiyuki Masui | 経口医薬品並びに加工食品 |
| US5883103A (en) * | 1995-06-07 | 1999-03-16 | Shire Laboratories Inc. | Oral acyclovir delivery |
| FR2761265B1 (fr) * | 1997-03-28 | 1999-07-02 | Sanofi Sa | Composition pharmaceutique pour l'administration orale d'un derive du n-piperidino-3-pyrazolecarboxamide, de ses sels et de leurs solvates |
-
1998
- 1998-10-15 WO PCT/EP1998/006544 patent/WO1999021534A1/en not_active Ceased
- 1998-10-15 EP EP98955458A patent/EP0996429B1/en not_active Expired - Lifetime
- 1998-10-15 JP JP2000517694A patent/JP2001520984A/ja active Pending
- 1998-10-15 PT PT98955458T patent/PT996429E/pt unknown
- 1998-10-15 ES ES98955458T patent/ES2191977T3/es not_active Expired - Lifetime
- 1998-10-15 DE DE69811233T patent/DE69811233T2/de not_active Expired - Lifetime
- 1998-10-15 DK DK98955458T patent/DK0996429T3/da active
- 1998-10-15 CN CNB988105934A patent/CN1190187C/zh not_active Expired - Fee Related
- 1998-10-15 AT AT98955458T patent/ATE232087T1/de active
-
2000
- 2000-04-26 NO NO20002133A patent/NO329755B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE69811233T2 (de) | 2003-11-20 |
| JP2001520984A (ja) | 2001-11-06 |
| CN1190187C (zh) | 2005-02-23 |
| DK0996429T3 (da) | 2003-05-26 |
| WO1999021534A1 (en) | 1999-05-06 |
| ATE232087T1 (de) | 2003-02-15 |
| ES2191977T3 (es) | 2003-09-16 |
| NO20002133D0 (no) | 2000-04-26 |
| EP0996429B1 (en) | 2003-02-05 |
| CN1278164A (zh) | 2000-12-27 |
| NO329755B1 (no) | 2010-12-13 |
| NO20002133L (no) | 2000-04-26 |
| DE69811233D1 (de) | 2003-03-13 |
| EP0996429A1 (en) | 2000-05-03 |
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