PT979244E - Derivados de ciclosporina, sua preparacao e composicoes farmaceuticas que os contem - Google Patents

Derivados de ciclosporina, sua preparacao e composicoes farmaceuticas que os contem

Info

Publication number: PT979244E
Authority: PT; Portugal
Prior art keywords: contain; preparation; pharmaceutical compositions; cyclosporin derivatives; radical
Prior art date: 1997-04-30

Application number

PT98922872T

Other languages

English (en)

Inventor

Serge Mignani

Jean-Claude Barriere

Jean-Christophe Carry

Michel Evers

Bruno Filoche

Georges Bashiardes

Claude Bensoussan

Jean-Christophe Gueguen

Original Assignee

Aventis Pharma Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-04-30

Filing date

1998-04-27

Publication date

2005-06-30

1998-04-27 Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa

2005-06-30 Publication of PT979244E publication Critical patent/PT979244E/pt

Links

PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical class CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 title abstract 2
239000008194 pharmaceutical composition Substances 0.000 title 1
208000005074 Retroviridae Infections Diseases 0.000 abstract 1
238000011321 prophylaxis Methods 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
238000011282 treatment Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
- C07K7/645—Cyclosporins; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Virology (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Molecular Biology (AREA)
Immunology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

PT98922872T 1997-04-30 1998-04-27 Derivados de ciclosporina, sua preparacao e composicoes farmaceuticas que os contem PT979244E (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9705351A FR2762843B1 (fr)	1997-04-30	1997-04-30	Nouveaux derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number	Publication Date
PT979244E true PT979244E (pt)	2005-06-30

Family

ID=9506467

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT98922872T PT979244E (pt)	1997-04-30	1998-04-27	Derivados de ciclosporina, sua preparacao e composicoes farmaceuticas que os contem

Country Status (13)

Country	Link
US (1)	US5977067A (pt)
EP (1)	EP0979244B1 (pt)
JP (1)	JP2001524105A (pt)
AT (1)	ATE290015T1 (pt)
AU (1)	AU7535798A (pt)
DE (1)	DE69829175T2 (pt)
ES (1)	ES2236902T3 (pt)
FR (1)	FR2762843B1 (pt)
MA (1)	MA26488A1 (pt)
PT (1)	PT979244E (pt)
TN (1)	TNSN98057A1 (pt)
WO (1)	WO1998049193A1 (pt)
ZA (1)	ZA983618B (pt)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20030220234A1 (en)	1998-11-02	2003-11-27	Selvaraj Naicker	Deuterated cyclosporine analogs and their use as immunodulating agents
CN100334106C (zh)	2001-10-19	2007-08-29	伊索泰克尼卡股份有限公司	环孢菌素类似物的合成
DE60233150D1 (de) *	2001-10-19	2009-09-10	Isotechnika Inc	Neue cyclosporin-analoge mikroemulsionsvorkonzentrate
KR20040039622A (ko) *	2002-11-04	2004-05-12	주식회사 엘지생활건강	모발 성장 효과를 갖는 사이클로스포린 3 위치 유도체를유효성분으로 하는 모발 성장 촉진제
US20060130158A1 (en) *	2002-08-30	2006-06-15	Turner Andrew J	Modified transferrin fusion proteins comprising duplicate transferrin amino or carboxy terminal domains
CA2518265A1 (en)	2003-03-17	2004-09-30	Albany Molecular Research, Inc.	Novel cyclosporins
ATE488252T1 (de) *	2003-05-05	2010-12-15	Virxsys Corp	Erhöhte transduktion mit abc- transportersubstratenhemmern
JP2008514701A (ja)	2004-09-29	2008-05-08	エーエムアールテクノロジーインコーポレイテッド	シクロスポリンアルキン類似体およびそれらの薬学的使用
US7511013B2 (en)	2004-09-29	2009-03-31	Amr Technology, Inc.	Cyclosporin analogues and their pharmaceutical uses
EP1802650B1 (en) *	2004-10-01	2011-10-26	Scynexis, Inc.	3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis c infection
US7196161B2 (en) *	2004-10-01	2007-03-27	Scynexis Inc.	3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis C infection
WO2006041631A2 (en)	2004-10-06	2006-04-20	Amr Technology, Inc.	Novel cyclosporin alkynes and their utility as pharmaceutical agents
WO2007041631A1 (en) *	2005-09-30	2007-04-12	Scynexis, Inc.	ARYIiALKYL AND HETEROARYLALKYL DERIVATIVES OF CYCLOSPORINE A FOR THE TREATMENT AND PREVENTION OF VIRAL INFECTION
BRPI0616476A2 (pt) *	2005-09-30	2011-06-21	Scynexis Inc	uso de uma quantidade terapeuticamente eficaz de um derivado de ciclosporina, e, composição farmacêutica
US9839667B2 (en)	2005-10-14	2017-12-12	Allergan, Inc.	Prevention and treatment of ocular side effects with a cyclosporin
WO2007047334A1 (en) *	2005-10-14	2007-04-26	Allergan, Inc.	Prevention and treatment of drug-associated ocular side effects with a cyclosporin
US7745400B2 (en) *	2005-10-14	2010-06-29	Gregg Feinerman	Prevention and treatment of ocular side effects with a cyclosporin
US8188052B2 (en)	2006-05-19	2012-05-29	Scynexis, Inc.	Method for the treatment and prevention of ocular disorders
WO2007141395A1 (fr) *	2006-06-02	2007-12-13	Claude Annie Perrichon	Gestion des electrons actifs
WO2008069917A2 (en)	2006-11-20	2008-06-12	Scynexis, Inc.	Novel cyclic peptides
WO2008127613A1 (en) *	2007-04-11	2008-10-23	Scynexis, Inc.	New pharmaceutical compositions
US20090306033A1 (en) *	2008-06-06	2009-12-10	Keqiang Li	Novel cyclic peptides
CN102083852A (zh)	2008-06-06	2011-06-01	西尼克斯公司	环孢菌素类似物及其在治疗hcv感染中的应用
NZ590517A (en) *	2008-07-30	2012-12-21	Isotechnika Pharma Inc	Nonimmunosuppressive cyclosporine analogue molecules
DE102008060549A1 (de)	2008-12-04	2010-06-10	MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V.	Wirkstoff-Peptid-Konstrukt zur extrazellulären Anreicherung
JP5780969B2 (ja) *	2008-12-31	2015-09-16	サイネクシス，インコーポレーテッド	シクロスポリンａの誘導体
EP2391376A4 (en)	2009-01-30	2012-08-01	Enanta Pharm Inc	ANALOGUES OF CYCLOSPORIN FOR PREVENTING OR TREATING HEPATITIS C INFECTION
US8481483B2 (en) *	2009-02-19	2013-07-09	Enanta Pharmaceuticals, Inc.	Cyclosporin analogues
US20100305047A1 (en) *	2009-05-27	2010-12-02	Allergan, Inc.	Cyclosporin derivatives for enhancing the growth of hair
WO2010138423A1 (en) *	2009-05-27	2010-12-02	Allergan, Inc.	Cyclosporin derivatives for treating inflammatory diseases and conditions
US8685917B2 (en) *	2009-07-09	2014-04-01	Enanta Pharmaceuticals, Inc.	Cyclosporin analogues
KR20120125610A (ko) *	2009-12-30	2012-11-16	싸이넥시스, 인크.	시클로스포린 유사체
RU2013119869A (ru) *	2010-10-12	2014-11-20	Аллерган, Инк.	Аналоги циклоспорина
CA2814191A1 (en)	2010-10-12	2012-04-19	Allergan, Inc.	Cyclosporin analogs
CN107496902B (zh)	2010-12-15	2022-01-18	康卓维尔制药公司	在氨基酸1和3位修改的环孢菌素类似分子
DE102011111991A1 (de) *	2011-08-30	2013-02-28	Lead Discovery Center Gmbh	Neue Cyclosporin-Derivate
EP2705856A1 (en)	2012-09-07	2014-03-12	Deutsches Zentrum für Neurodegenerative Erkrankungen e.V.	Compounds for the treatment of neurodegenerative disorders
CN104603146B (zh)	2012-09-29	2018-01-02	诺华股份有限公司	环肽类化合物及其作为药物的用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0194972B1 (en) *	1985-03-11	1992-07-29	Sandoz Ag	Novel cyclosporins
US4814323A (en) *	1986-03-25	1989-03-21	Andrieu J M	Process for the treatment and the prevention of AIDS and other disorders induced by the LAV/HTLV III virus
US4798823A (en) *	1987-06-03	1989-01-17	Merck & Co., Inc.	New cyclosporin analogs with modified "C-9 amino acids"
US4885276A (en) *	1987-06-03	1989-12-05	Merck & Co., Inc.	Cyclosporin analogs with modified "C-9 amino acids"
ATE148469T1 (de) *	1990-11-02	1997-02-15	Sandoz Ag	Zyklosporine
US5512555A (en) *	1994-07-21	1996-04-30	Merck & Co., Inc.	Method of treating sweat-related conditions using finasteride, epristeride and a cholestan-3-one
ATE209216T1 (de) *	1995-07-17	2001-12-15	Chem Ag C	Cyclosporin-derivate mit anti-hiv-wirkung

1997
- 1997-04-30 FR FR9705351A patent/FR2762843B1/fr not_active Expired - Fee Related
1998
- 1998-04-27 AT AT98922872T patent/ATE290015T1/de active
- 1998-04-27 DE DE69829175T patent/DE69829175T2/de not_active Expired - Lifetime
- 1998-04-27 JP JP54666498A patent/JP2001524105A/ja active Pending
- 1998-04-27 AU AU75357/98A patent/AU7535798A/en not_active Abandoned
- 1998-04-27 MA MA25048A patent/MA26488A1/fr unknown
- 1998-04-27 ES ES98922872T patent/ES2236902T3/es not_active Expired - Lifetime
- 1998-04-27 EP EP98922872A patent/EP0979244B1/fr not_active Expired - Lifetime
- 1998-04-27 PT PT98922872T patent/PT979244E/pt unknown
- 1998-04-27 WO PCT/FR1998/000838 patent/WO1998049193A1/fr not_active Ceased
- 1998-04-29 ZA ZA983618A patent/ZA983618B/xx unknown
- 1998-04-29 TN TNTNSN98057A patent/TNSN98057A1/fr unknown
- 1998-04-30 US US09/069,959 patent/US5977067A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DE69829175T2 (de)	2006-02-16
ATE290015T1 (de)	2005-03-15
ZA983618B (en)	1998-11-04
ES2236902T3 (es)	2005-07-16
US5977067A (en)	1999-11-02
FR2762843B1 (fr)	1999-12-10
AU7535798A (en)	1998-11-24
FR2762843A1 (fr)	1998-11-06
WO1998049193A1 (fr)	1998-11-05
MA26488A1 (fr)	2004-12-20
TNSN98057A1 (fr)	2005-03-15
DE69829175D1 (de)	2005-04-07
JP2001524105A (ja)	2001-11-27
EP0979244A1 (fr)	2000-02-16
EP0979244B1 (fr)	2005-03-02

Publication	Publication Date	Title
PT979244E (pt)	2005-06-30	Derivados de ciclosporina, sua preparacao e composicoes farmaceuticas que os contem
PT948527E (pt)	2002-11-29	Novos derivados de ciclosporina sua preparacao e composicoes farmaceuticas que os contem
PT951474E (pt)	2002-11-29	Novos derivados da ciclosporina sua preparacao e composicoes farmaceuticas que os contem
BR0215240A (pt)	2004-10-26	Derivados de calcona e seu uso no tratamento de doenças
BR0008059A (pt)	2002-03-26	Composições de valdecoxib
SE9504661D0 (sv)	1995-12-22	New compounds
BG101118A (en)	1998-04-30	Therapeutical compounds
PT951473E (pt)	2002-11-29	Novos derivados da ciclosporina sua preparacao e composicoes farmaceuticas que os contem
KR0141913B1 (en)	1998-06-01	Anti-virus agents
DE59200277D1 (de)	1994-08-18	Substituierte Diaminophthalimide und Analoga.
BR0113590A (pt)	2003-07-22	7-oxo-piridopirimidinas
FI972434A0 (fi)	1997-06-06	Lamotrigiiniä sisältävä farmaseuttinen koostumus
TR200000349T2 (tr)	2000-09-21	Fizyolojik olarak kabul edilebilir vanadyum bileşimlerinin, tuzlarının ve komplekslerinin kullanımı.
DK0387821T3 (da)	1994-09-19	2-Alkyl-4-arylmethylchinoliner, deres anvendelse og lægemidler fremstillet hermed
GR3019274T3 (en)	1996-06-30	Substituted 3-piperazinylalkyl-2,3-dihydro-4H-1,3-benzoxazine-4-ones, their preparation and their therapeutical use
PH27446A (en)	1993-07-02	Compound with gastric acid inhibitory effect
MY121604A (en)	2006-02-28	Combination therapy for hiv infection using the hiv protease inhibitor indinavir and the reverse transcriptase inhibitor 3tc together with azt
BR0011845A (pt)	2002-03-05	Complexo farmacêutico
EP1411956B8 (en)	2005-10-05	Use of oversulfated polysaccharides as inhibitors of hiv
IL112110A0 (en)	1995-03-15	Octahydro-1h-isoindoles and pharmaceutical compositions containing them
PT989994E (pt)	2005-08-31	Derivados de estreptograminas, a sua preparacao e as composicoes que os contem
BR0213463A (pt)	2004-11-09	Composições farmacêuticas contendo macrólidos
KR960700053A (ko)	1996-01-19	방사선회복제로서 리루졸의 이용(application of riluzole as a radiorestorer)