PT97562A - Processo para a preparacao de uma composicao farmaceutica contendo um nucleo de diclofenac ou de piroxicamo e um revestimento de cobertura de uma prostaglandina - Google Patents
Processo para a preparacao de uma composicao farmaceutica contendo um nucleo de diclofenac ou de piroxicamo e um revestimento de cobertura de uma prostaglandinaInfo
- Publication number
- PT97562A PT97562A PT97562A PT9756291A PT97562A PT 97562 A PT97562 A PT 97562A PT 97562 A PT97562 A PT 97562A PT 9756291 A PT9756291 A PT 9756291A PT 97562 A PT97562 A PT 97562A
- Authority
- PT
- Portugal
- Prior art keywords
- coating
- diclofenac
- pharmaceutical composition
- pyroxicamo
- prostaglandine
- Prior art date
Links
- 239000011248 coating agent Substances 0.000 title abstract 5
- 238000000576 coating method Methods 0.000 title abstract 5
- 229960001259 diclofenac Drugs 0.000 title abstract 2
- DCOPUUMXTXDBNB-UHFFFAOYSA-N diclofenac Chemical compound OC(=O)CC1=CC=CC=C1NC1=C(Cl)C=CC=C1Cl DCOPUUMXTXDBNB-UHFFFAOYSA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 1
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 abstract 2
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 abstract 2
- 150000003180 prostaglandins Chemical class 0.000 abstract 2
- 229960002702 piroxicam Drugs 0.000 abstract 1
- QYSPLQLAKJAUJT-UHFFFAOYSA-N piroxicam Chemical compound OC=1C2=CC=CC=C2S(=O)(=O)N(C)C=1C(=O)NC1=CC=CC=N1 QYSPLQLAKJAUJT-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51835390A | 1990-05-03 | 1990-05-03 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT97562A true PT97562A (pt) | 1992-02-28 |
| PT97562B PT97562B (pt) | 1998-08-31 |
Family
ID=24063571
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT97562A PT97562B (pt) | 1990-05-03 | 1991-05-03 | Processo para a preparacao de uma composicao farmaceutica contendo um nucleo de diclofenac ou de piroxicamo e um revestimento de cobertura de uma prostaglandina |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US5601843A (pt) |
| EP (1) | EP0527887B1 (pt) |
| AT (1) | ATE121625T1 (pt) |
| AU (1) | AU7876491A (pt) |
| CA (1) | CA2082944C (pt) |
| DE (1) | DE69109286T2 (pt) |
| DK (1) | DK0527887T3 (pt) |
| ES (1) | ES2071312T3 (pt) |
| GR (1) | GR3015939T3 (pt) |
| IE (1) | IE68596B1 (pt) |
| IL (1) | IL98033A (pt) |
| NZ (1) | NZ238024A (pt) |
| PT (1) | PT97562B (pt) |
| WO (1) | WO1991016895A1 (pt) |
| ZA (1) | ZA913353B (pt) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0527887T3 (da) * | 1990-05-03 | 1995-07-03 | Searle & Co | Farmaceutisk præparat |
| FI93924C (fi) * | 1991-09-17 | 1995-06-26 | Martti Lauri Antero Marvola | Menetelmä säädellysti lääkeainetta vapauttavan valmisteen valmistamiseksi |
| US5324746A (en) * | 1993-02-12 | 1994-06-28 | Mckee Rex N | Method of treating damaged mucosal and epithelial tissues with misoprostol |
| DE4341442C2 (de) * | 1993-12-04 | 1998-11-05 | Lohmann Therapie Syst Lts | Vorrichtung zur kontrollierten Freisetzung von Wirkstoffen sowie ihre Verwendung |
| CA2231550A1 (en) * | 1995-09-27 | 1997-04-03 | Merck Frosst Canada Inc. | Compositions for treating inflammation containing certain prostaglandins and a selective cyclooxygenase-2 inhibitor |
| US6623759B2 (en) * | 1996-06-28 | 2003-09-23 | Astrazeneca Ab | Stable drug form for oral administration with benzimidazole derivatives as active ingredient and process for the preparation thereof |
| US6103765A (en) | 1997-07-09 | 2000-08-15 | Androsolutions, Inc. | Methods for treating male erectile dysfunction |
| KR20010021625A (ko) | 1997-07-09 | 2001-03-15 | 추후보정 | 개선된 남성발기 기능장애 치료방법 및 그 조성물 |
| CA2241342C (en) * | 1998-06-15 | 2000-02-08 | Bernard Charles Sherman | Pharmaceutical tablets comprising an nsaid and a prostaglandin |
| GB9814215D0 (en) * | 1998-07-01 | 1998-09-02 | Norton Healthcare Ltd | Anti-inflammatory pharmaceutical formulations |
| US6319519B2 (en) | 1998-07-07 | 2001-11-20 | Norton Healthcare Ltd. | Anti-inflammatory pharmaceutical formulations |
| GB9819685D0 (en) * | 1998-09-10 | 1998-11-04 | Norton Healthcare Ltd | Anti-inflammatory pharmaceutical formulations |
| US6387410B1 (en) | 1998-09-10 | 2002-05-14 | Norton Healthcare Ltd | Anti-inflammatory pharmaceutical formulations |
| US6514525B2 (en) | 1998-09-10 | 2003-02-04 | Norton Healthcare Ltd | Anti-inflammatory pharmaceutical formulations |
| SE9803761D0 (sv) * | 1998-11-04 | 1998-11-04 | Synphora Ab | Method to avoid increased iridial pigmentation during prostaglandin treatment |
| US7429407B2 (en) * | 1998-12-30 | 2008-09-30 | Aeromatic Fielder Ag | Process for coating small bodies, including tablets |
| CA2259727A1 (en) * | 1999-01-18 | 2000-07-18 | Bernard Charles Sherman | A two-layer pharmaceutical tablet comprising an nsaid and misoprostol |
| US6183779B1 (en) * | 1999-03-22 | 2001-02-06 | Pharmascience Inc. | Stabilized pharmaceutical composition of a nonsteroidal anti-inflammatory agent and a prostaglandin |
| CA2277407A1 (en) * | 1999-07-14 | 2001-01-14 | Bernard Charles Sherman | Pharmaceutical tablet comprising an nsaid and misoprostol |
| JP2003510347A (ja) * | 1999-10-01 | 2003-03-18 | ノートン ヘルスケアー リミテッド | 抗炎症医薬品製剤 |
| US6761895B2 (en) * | 2000-04-17 | 2004-07-13 | Yamanouchi Pharmaceutical Co., Ltd. | Drug delivery system for averting pharmacokinetic drug interaction and method thereof |
| US8206741B2 (en) | 2001-06-01 | 2012-06-26 | Pozen Inc. | Pharmaceutical compositions for the coordinated delivery of NSAIDs |
| EP2316469A1 (en) | 2002-02-22 | 2011-05-04 | Shire LLC | Delivery system and methods for protecting and administering dextroamphetamine |
| WO2004064815A1 (en) * | 2003-01-21 | 2004-08-05 | Smartrix Technologies Inc. | Oral dosage formulation |
| DE602004007315D1 (de) * | 2003-03-03 | 2007-08-16 | Personnes A Responsibilite Lim | Stabilisierte pharmazeutische Zusammensetzung enthaltend einen NSAID und einen Prostaglandin |
| WO2004091579A1 (en) * | 2003-04-16 | 2004-10-28 | Pharmacia Corporation | Stabilized prostaglandin formulation |
| US7241746B2 (en) | 2003-08-06 | 2007-07-10 | Regena Therapeutics, Lc | Method and composition for treating periodontal disease |
| US20050163847A1 (en) * | 2004-01-21 | 2005-07-28 | Andrx Pharmaceuticals, Llc | Pharmaceutical formulations containing a non-steroidal antiinflammatory drug and an antiulcerative drug |
| US20060024368A1 (en) * | 2004-07-30 | 2006-02-02 | Reza Fassihi | Compressed composite delivery system for release-rate modulation of bioactives |
| US20060073202A1 (en) * | 2004-10-05 | 2006-04-06 | Rocca Jose G | Dual component medicament delivery system |
| US8067451B2 (en) | 2006-07-18 | 2011-11-29 | Horizon Pharma Usa, Inc. | Methods and medicaments for administration of ibuprofen |
| US20080020040A1 (en) * | 2006-07-18 | 2008-01-24 | Horizon Therapeutics, Inc. | Unit dose form for administration of ibuprofen |
| US20080021078A1 (en) * | 2006-07-18 | 2008-01-24 | Horizon Therapeutics, Inc. | Methods and medicaments for administration of ibuprofen |
| US20150224056A1 (en) * | 2006-07-18 | 2015-08-13 | Horizon Pharma Usa, Inc. | Pharmaceutical compositions of ibuprofen and famotidine |
| US8067033B2 (en) | 2007-11-30 | 2011-11-29 | Horizon Pharma Usa, Inc. | Stable compositions of famotidine and ibuprofen |
| EP2063873A2 (en) * | 2006-08-31 | 2009-06-03 | Horizon Therapeutics, Inc. | Nsaid dose unit formulations with h2-receptor antagonists and methods of use |
| WO2008146178A2 (en) | 2007-05-30 | 2008-12-04 | Wockhardt Research Centre | A novel tablet dosage form |
| AU2009290712A1 (en) | 2008-09-09 | 2010-03-18 | Astrazeneca Ab | Method for delivering a pharmaceutical composition to patient in need thereof |
| EP2210595A1 (en) | 2009-01-14 | 2010-07-28 | LEK Pharmaceuticals d.d. | Active coating of pharmaceutical dosage forms |
| JP2012531430A (ja) * | 2009-06-25 | 2012-12-10 | ポーゼン インコーポレイテッド | アスピリン療法を必要とする患者を治療するための方法 |
| EA201290026A1 (ru) | 2009-06-25 | 2012-07-30 | Астразенека Аб | Способ лечения пациента, имеющего риск развития язвы, связанной с приемом нестероидных противовоспалительных средств (nsaid) |
| EA028049B1 (ru) | 2011-12-28 | 2017-10-31 | Поузен Инк. | Улучшенные композиции и способы доставки омепразола и ацетилсалициловой кислоты |
| WO2017180259A1 (en) * | 2016-04-11 | 2017-10-19 | University Of Utah Research Foundation | Methods for treating nsaid-induced cardiovascular, cerebrovascular, or renovascular adverse events |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2135881B (en) * | 1983-03-02 | 1986-09-17 | Erba Farmitalia | Pharmaceutical compositions for inhibiting or reducing gastrointestinal side effects of non-steroidal anti-inflammatory drugs |
| IT1190400B (it) * | 1985-10-04 | 1988-02-16 | Istituto Biochimico Italiano | Derivati dell'acido 19,20-bis,nor-prostanoico ad attivita' antiulcera e anoressivca,procedimento per la loro preparazione e composizioni farmaceutiche |
| US4707495A (en) * | 1985-10-28 | 1987-11-17 | Ortho Pharmaceutical | Peptic ulcer treatment method |
| US4975283A (en) * | 1985-12-12 | 1990-12-04 | Bristol-Myers Squibb Company | Stabilized enteric coated aspirin granules and process for preparation |
| DE3603576A1 (de) * | 1986-02-06 | 1987-08-13 | Code Kaffee Handel | Verwendung von gerbstoffen und/oder chlorogensaeure sowie nahrungs-, genuss- und/oder arzneimittel mit gerbstoff- und/oder chlorogensaeurezusatz |
| JPH01139528A (ja) * | 1987-11-24 | 1989-06-01 | Showa Denko Kk | 抗潰瘍剤 |
| DK0527887T3 (da) * | 1990-05-03 | 1995-07-03 | Searle & Co | Farmaceutisk præparat |
-
1991
- 1991-05-01 DK DK91909572.9T patent/DK0527887T3/da active
- 1991-05-01 ES ES91909572T patent/ES2071312T3/es not_active Expired - Lifetime
- 1991-05-01 DE DE69109286T patent/DE69109286T2/de not_active Expired - Lifetime
- 1991-05-01 EP EP91909572A patent/EP0527887B1/en not_active Expired - Lifetime
- 1991-05-01 AT AT91909572T patent/ATE121625T1/de not_active IP Right Cessation
- 1991-05-01 AU AU78764/91A patent/AU7876491A/en not_active Abandoned
- 1991-05-01 WO PCT/US1991/002980 patent/WO1991016895A1/en not_active Ceased
- 1991-05-01 CA CA002082944A patent/CA2082944C/en not_active Expired - Lifetime
- 1991-05-02 IE IE148691A patent/IE68596B1/en not_active IP Right Cessation
- 1991-05-02 NZ NZ238024A patent/NZ238024A/xx unknown
- 1991-05-02 IL IL9803391A patent/IL98033A/en not_active IP Right Cessation
- 1991-05-03 PT PT97562A patent/PT97562B/pt not_active IP Right Cessation
- 1991-05-03 ZA ZA913353A patent/ZA913353B/xx unknown
-
1994
- 1994-07-18 US US08/276,299 patent/US5601843A/en not_active Expired - Lifetime
-
1995
- 1995-04-27 GR GR950400874T patent/GR3015939T3/el unknown
-
1997
- 1997-02-03 US US08/794,027 patent/US5698225A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| GR3015939T3 (en) | 1995-07-31 |
| IE68596B1 (en) | 1996-06-26 |
| IE911486A1 (en) | 1991-11-06 |
| US5601843A (en) | 1997-02-11 |
| NZ238024A (en) | 1993-08-26 |
| CA2082944C (en) | 1998-11-24 |
| ZA913353B (en) | 1993-04-28 |
| DE69109286D1 (de) | 1995-06-01 |
| IL98033A (en) | 1995-07-31 |
| DK0527887T3 (da) | 1995-07-03 |
| EP0527887A1 (en) | 1993-02-24 |
| IL98033A0 (en) | 1992-06-21 |
| PT97562B (pt) | 1998-08-31 |
| EP0527887B1 (en) | 1995-04-26 |
| ES2071312T3 (es) | 1995-06-16 |
| US5698225A (en) | 1997-12-16 |
| ATE121625T1 (de) | 1995-05-15 |
| CA2082944A1 (en) | 1991-11-04 |
| DE69109286T2 (de) | 1995-09-28 |
| WO1991016895A1 (en) | 1991-11-14 |
| AU7876491A (en) | 1991-11-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BB1A | Laying open of patent application |
Effective date: 19911104 |
|
| FG3A | Patent granted, date of granting |
Effective date: 19980519 |
|
| MM4A | Annulment/lapse due to non-payment of fees, searched and examined patent |
Free format text: MAXIMUM VALIDITY LIMIT REACHED Effective date: 20130520 |