PT89729A - Processo para a preparacao de derivados de cefalosporina e de composicoes farmaceuticas que os contem - Google Patents
Processo para a preparacao de derivados de cefalosporina e de composicoes farmaceuticas que os contemInfo
- Publication number
- PT89729A PT89729A PT89729A PT8972989A PT89729A PT 89729 A PT89729 A PT 89729A PT 89729 A PT89729 A PT 89729A PT 8972989 A PT8972989 A PT 8972989A PT 89729 A PT89729 A PT 89729A
- Authority
- PT
- Portugal
- Prior art keywords
- preparation
- pharmaceutical compositions
- compositions containing
- derivatives
- cefalosporin
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000001782 cephems Chemical class 0.000 abstract 3
- 208000035143 Bacterial infection Diseases 0.000 abstract 2
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 2
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 2
- UDTVQXNZIKQKOI-BAFYGKSASA-N (6r)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-4-carboxylic acid Chemical class C1=CC(C(=O)O)S[C@@H]2CC(=O)N21 UDTVQXNZIKQKOI-BAFYGKSASA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
- C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3804841A DE3804841A1 (de) | 1988-02-17 | 1988-02-17 | Cephalosporinderivate und verfahren zu ihrer herstellung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT89729A true PT89729A (pt) | 1989-10-04 |
| PT89729B PT89729B (pt) | 1994-03-31 |
Family
ID=6347539
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT89729A PT89729B (pt) | 1988-02-17 | 1989-02-16 | Processo para a preparacao de derivados de cefalosporina e de composicoes farmaceuticas que os contem |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US5100887A (pt) |
| EP (1) | EP0329008B1 (pt) |
| JP (1) | JP2509689B2 (pt) |
| KR (1) | KR0140886B1 (pt) |
| CN (1) | CN1043042C (pt) |
| AT (1) | ATE183188T1 (pt) |
| AU (1) | AU613152B2 (pt) |
| CA (1) | CA1339421C (pt) |
| DD (1) | DD283629A5 (pt) |
| DE (2) | DE3804841A1 (pt) |
| DK (1) | DK174730B1 (pt) |
| DZ (1) | DZ1324A1 (pt) |
| ES (1) | ES2136591T3 (pt) |
| FI (1) | FI93458C (pt) |
| GR (1) | GR3031542T3 (pt) |
| HU (1) | HU205121B (pt) |
| IL (1) | IL89303A0 (pt) |
| MY (1) | MY104937A (pt) |
| NO (1) | NO173736C (pt) |
| NZ (1) | NZ227990A (pt) |
| PT (1) | PT89729B (pt) |
| TN (1) | TNSN89016A1 (pt) |
| ZA (1) | ZA891162B (pt) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3809561A1 (de) * | 1988-03-22 | 1989-10-05 | Hoechst Ag | Ester der 7-(2-(2-aminothiazol-4-yl)-2-(z)- hydroxyiminoacetamido)-3-methoxymethyl-3-cephem-4-carbonsaeure, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zubereitungen |
| DE3919259A1 (de) * | 1989-06-13 | 1990-12-20 | Hoechst Ag | Kristalline cephem-saeureadditionssalze und verfahren zu ihrer herstellung |
| YU48484B (sh) * | 1991-05-24 | 1998-09-18 | Hoechst Aktiengesellschaft | Kristalne kiselinske adicione soli diastereomerno čistih 1-(2,2-dimetilpropioniloksi)-etilestara 3-cefem-4-karbonske kiseline |
| EP0531875B1 (de) * | 1991-09-07 | 2004-03-24 | Aventis Pharma Deutschland GmbH | Diastereomer des 3-Cephem-4-carbonsäure-1-(-isopropoxycarbonyloxy)ethylesters und Verfahren zu dessen Herstellung |
| TW212181B (pt) * | 1992-02-14 | 1993-09-01 | Hoechst Ag | |
| EP0570849B1 (de) * | 1992-05-21 | 1998-03-25 | Hoechst Aktiengesellschaft | Verfahren zur Spaltung von Cephalosporin Prodrugestern zu 7-Amino-3-methoxymethylceph-3-em-4-carbonsäure |
| LT3871B (en) | 1993-11-30 | 1996-04-25 | Hoechst Ag | Additive crystalline salts of pure diastereomers of 1-cefem-4-carboxylic acid 1-(2,2-dimethyl-propionyloxy)ethyl esters, process for the preparation thereof, pharmaceutical compositions and process for the preparation thereof |
| DE4418957A1 (de) * | 1994-05-31 | 1995-12-07 | Merck Patent Gmbh | Cefixim-Zubereitung |
| SE524569C2 (sv) * | 1998-11-20 | 2004-08-31 | Perstorp Ab | Förfarande för framställning av en allyloxikarboxylsyra, användning av allyoxikarboxylsyran framställd enligt förfarandet som komponent i oligomera och polymera bindemedel samt 6-allyloxihexansyra framställd enligt förfarandet |
| AT408226B (de) * | 1999-05-05 | 2001-09-25 | Biochemie Gmbh | Kristalliner 7-(2-(2-formylaminothiazol-4-yl)-2 |
| AU2003282267A1 (en) * | 2002-11-22 | 2004-06-18 | Orchid Chemicals And Pharmaceuticals Ltd | An improved process for the preparation of cefpodoxime proxetil |
| WO2005019227A1 (en) * | 2003-08-22 | 2005-03-03 | Orchid Chemicals & Pharmaceuticals Ltd | Process for the preparation of cephalosporin antibiotic |
| JP2010047550A (ja) * | 2008-08-25 | 2010-03-04 | Daicel Chem Ind Ltd | アルコキシアルカンカルボン酸エステルの製造方法 |
| EP3398038B1 (en) | 2016-02-04 | 2024-01-17 | Apple Inc. | Controlling electronic devices and displaying information based on wireless ranging |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4298606A (en) * | 1974-12-19 | 1981-11-03 | Takeda Chemical Industries, Ltd. | Thiazolylacetamido compounds |
| JPS5760345B2 (pt) * | 1974-12-19 | 1982-12-18 | Takeda Chemical Industries Ltd | |
| DK154939C (da) * | 1974-12-19 | 1989-06-12 | Takeda Chemical Industries Ltd | Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf |
| US4668783A (en) * | 1974-12-19 | 1987-05-26 | Takeda Chemical Industries, Ltd. | Thiazolylacetamido cephalosporin compounds |
| US4203899A (en) * | 1974-12-19 | 1980-05-20 | Takeda Chemical Industries, Ltd. | Thiazolylacetamido compounds |
| DE2760123C2 (de) * | 1976-01-23 | 1986-04-30 | Roussel-Uclaf, Paris | 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen |
| JPS6011713B2 (ja) * | 1976-09-08 | 1985-03-27 | 武田薬品工業株式会社 | セフアロスポリン誘導体およびその製造法 |
| DE2714880A1 (de) * | 1977-04-02 | 1978-10-26 | Hoechst Ag | Cephemderivate und verfahren zu ihrer herstellung |
| US4409215A (en) * | 1979-11-19 | 1983-10-11 | Fujisawa Pharmaceutical Co., Ltd. | 7-Acylamino-3-substituted cephalosporanic acid derivatives and processes for the preparation thereof |
| FR2476087A1 (fr) * | 1980-02-18 | 1981-08-21 | Roussel Uclaf | Nouvelles oximes derivees de l'acide 3-alkyloxy ou 3-alkyl-thiomethyl 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments |
| US4486425A (en) * | 1980-09-30 | 1984-12-04 | Sankyo Company Limited | 7-[2-(2-Aminothiazol-4-yl)-2-(syn)-methoxyiminoacetamido]-3-methoxymethyl-3-cephem-4-carboxylates |
| JPS5759894A (en) * | 1980-09-30 | 1982-04-10 | Sankyo Co Ltd | Cephalosporin for oral administration |
| JPS609757B2 (ja) * | 1981-07-16 | 1985-03-12 | 三共株式会社 | 経口用セフアロスポリン化合物 |
| GB8400024D0 (en) * | 1984-01-03 | 1984-02-08 | Glaxo Group Ltd | Cephalosporin antibiotics |
| JPH0631259B2 (ja) * | 1984-02-17 | 1994-04-27 | 三共株式会社 | 経口用セフアロスポリン化合物 |
| DE3809561A1 (de) * | 1988-03-22 | 1989-10-05 | Hoechst Ag | Ester der 7-(2-(2-aminothiazol-4-yl)-2-(z)- hydroxyiminoacetamido)-3-methoxymethyl-3-cephem-4-carbonsaeure, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zubereitungen |
| DE3901405A1 (de) * | 1989-01-19 | 1990-07-26 | Hoechst Ag | Cephalosporinderivate und verfahren zu ihrer herstellung |
| US5063224A (en) * | 1990-07-09 | 1991-11-05 | Eli Lilly And Company | R-cefuroxime axetil |
-
1988
- 1988-02-17 DE DE3804841A patent/DE3804841A1/de not_active Ceased
-
1989
- 1989-02-09 ES ES89102198T patent/ES2136591T3/es not_active Expired - Lifetime
- 1989-02-09 DE DE58909854T patent/DE58909854D1/de not_active Expired - Lifetime
- 1989-02-09 EP EP89102198A patent/EP0329008B1/de not_active Expired - Lifetime
- 1989-02-09 AT AT89102198T patent/ATE183188T1/de not_active IP Right Cessation
- 1989-02-15 FI FI890722A patent/FI93458C/fi not_active IP Right Cessation
- 1989-02-15 IL IL89303A patent/IL89303A0/xx not_active IP Right Cessation
- 1989-02-15 MY MYPI89000186A patent/MY104937A/en unknown
- 1989-02-15 DD DD89325788A patent/DD283629A5/de unknown
- 1989-02-15 NZ NZ227990A patent/NZ227990A/xx unknown
- 1989-02-15 DZ DZ890025A patent/DZ1324A1/fr active
- 1989-02-15 ZA ZA891162A patent/ZA891162B/xx unknown
- 1989-02-15 KR KR1019890001708A patent/KR0140886B1/ko not_active Expired - Lifetime
- 1989-02-16 CN CN89100825A patent/CN1043042C/zh not_active Expired - Lifetime
- 1989-02-16 AU AU30031/89A patent/AU613152B2/en not_active Expired
- 1989-02-16 CA CA000591261A patent/CA1339421C/en not_active Expired - Lifetime
- 1989-02-16 PT PT89729A patent/PT89729B/pt not_active IP Right Cessation
- 1989-02-16 DK DK198900722A patent/DK174730B1/da not_active IP Right Cessation
- 1989-02-16 NO NO890657A patent/NO173736C/no not_active IP Right Cessation
- 1989-02-17 TN TNTNSN89016A patent/TNSN89016A1/fr unknown
- 1989-02-17 HU HU89800A patent/HU205121B/hu unknown
- 1989-02-17 JP JP1038163A patent/JP2509689B2/ja not_active Expired - Lifetime
-
1990
- 1990-07-23 US US07/555,807 patent/US5100887A/en not_active Ceased
-
1992
- 1992-11-19 US US07/978,980 patent/USRE34865E/en not_active Expired - Lifetime
-
1999
- 1999-10-15 GR GR990402629T patent/GR3031542T3/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG3A | Patent granted, date of granting |
Effective date: 19930923 |
|
| MM4A | Annulment/lapse due to non-payment of fees, searched and examined patent |
Free format text: MAXIMUM VALIDITY LIMIT REACHED Effective date: 20090216 |