PT89718B - Processo para a preparacao de novos derivados halogenados de fosfonatos uteis como inibidores da aspartato-transcarbamilase - Google Patents

Processo para a preparacao de novos derivados halogenados de fosfonatos uteis como inibidores da aspartato-transcarbamilase

Info

Publication number: PT89718B
Authority: PT; Portugal
Prior art keywords: asparate; preparation; halogenated derivatives; new halogenated; transcarbamylase
Prior art date: 1988-02-16

Application number

PT89718A

Other languages

English (en)

Other versions

PT89718A (pt

Inventor

Charles Danzin

Serge Halazy

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-02-16

Filing date

1989-02-15

Publication date

1994-03-31

1989-02-15 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1989-10-04 Publication of PT89718A publication Critical patent/PT89718A/pt

1994-03-31 Publication of PT89718B publication Critical patent/PT89718B/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

PT89718A 1988-02-16 1989-02-15 Processo para a preparacao de novos derivados halogenados de fosfonatos uteis como inibidores da aspartato-transcarbamilase PT89718B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP88400348A EP0328834A1 (en)	1988-02-16	1988-02-16	Novel aspartate transcarbamylase inhibitors

Publications (2)

Publication Number	Publication Date
PT89718A PT89718A (pt)	1989-10-04
PT89718B true PT89718B (pt)	1994-03-31

Family

ID=8200350

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT89718A PT89718B (pt)	1988-02-16	1989-02-15	Processo para a preparacao de novos derivados halogenados de fosfonatos uteis como inibidores da aspartato-transcarbamilase

Country Status (12)

Country	Link
EP (2)	EP0328834A1 (pt)
JP (1)	JPH02149589A (pt)
CN (1)	CN1036207A (pt)
AU (1)	AU609942B2 (pt)
DK (1)	DK69489A (pt)
FI (1)	FI890695L (pt)
HU (1)	HUT49142A (pt)
IL (1)	IL89287A (pt)
NO (1)	NO890644L (pt)
NZ (1)	NZ227978A (pt)
PT (1)	PT89718B (pt)
ZA (1)	ZA891078B (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0465297B1 (en) *	1990-07-04	1996-01-31	Merrell Dow Pharmaceuticals Inc.	9-Purinyl phosphonic acid derivatives
US5095007A (en) *	1990-10-24	1992-03-10	Ahluwalia Gurpreet S	Alteration of rate and character of hair growth
GB9200826D0 (en) *	1992-01-15	1992-03-11	Celltech Ltd	Peptidyl derivatives
CN109715597A (zh)	2016-09-14	2019-05-03	大金工业株式会社	含支链含氟化合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3425701A1 (de) *	1984-07-12	1986-01-16	Bayer Ag, 5090 Leverkusen	Verfahren zur herstellung von chlorierten phosphorylmethylcarbonyl-derivaten und neue zwischenprodukte zu ihrer herstellung
FR2590259B1 (fr) *	1985-11-20	1989-05-12	Roussel Uclaf	Procede de preparation de derives fluores de l'acide phosphonique, et produits obtenus par la mise en oeuvre de ce procede
FR2596393B1 (fr) *	1986-04-01	1988-06-03	Sanofi Sa	Derives de l'acide hydroxy-3 dihydroxyoxophosphorio-4 butanoique, leur procede de preparation, leur application comme medicament et les compositions les renfermant

1988
- 1988-02-16 EP EP88400348A patent/EP0328834A1/en not_active Withdrawn
1989
- 1989-02-10 ZA ZA891078A patent/ZA891078B/xx unknown
- 1989-02-13 AU AU29904/89A patent/AU609942B2/en not_active Ceased
- 1989-02-14 FI FI890695A patent/FI890695L/fi not_active Application Discontinuation
- 1989-02-14 NZ NZ227978A patent/NZ227978A/en unknown
- 1989-02-14 IL IL89287A patent/IL89287A/xx not_active IP Right Cessation
- 1989-02-15 NO NO89890644A patent/NO890644L/no unknown
- 1989-02-15 PT PT89718A patent/PT89718B/pt not_active IP Right Cessation
- 1989-02-15 EP EP89400420A patent/EP0331550A1/en not_active Ceased
- 1989-02-15 DK DK069489A patent/DK69489A/da not_active Application Discontinuation
- 1989-02-15 HU HU89767A patent/HUT49142A/hu unknown
- 1989-02-15 CN CN89100817A patent/CN1036207A/zh active Pending
- 1989-02-16 JP JP1035199A patent/JPH02149589A/ja active Pending

Also Published As

Publication number	Publication date
ZA891078B (en)	1989-10-25
CN1036207A (zh)	1989-10-11
AU2990489A (en)	1989-08-17
FI890695A0 (fi)	1989-02-14
EP0331550A1 (en)	1989-09-06
NO890644D0 (no)	1989-02-15
HUT49142A (en)	1989-08-28
FI890695A7 (fi)	1989-08-17
IL89287A (en)	1993-02-21
NZ227978A (en)	1990-10-26
EP0328834A1 (en)	1989-08-23
DK69489A (da)	1989-08-17
JPH02149589A (ja)	1990-06-08
DK69489D0 (da)	1989-02-15
NO890644L (no)	1989-08-17
IL89287A0 (en)	1989-09-10
PT89718A (pt)	1989-10-04
AU609942B2 (en)	1991-05-09
FI890695L (fi)	1989-08-17

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Legal Events

Date	Code	Title	Description
1994-03-31	FG3A	Patent granted, date of granting	Effective date: 19930923
1995-08-09	MM3A	Annulment or lapse	Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19950331

Date

Code

Title

Description

1994-03-31

FG3A

Patent granted, date of granting

Effective date: 19930923

1995-08-09

MM3A

Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19950331