IL89287A - Halogenated phosphonic acid derivatives and aspartate transcarbamylase inhibitors and compositions containing them for tumor therapy - Google Patents

Halogenated phosphonic acid derivatives and aspartate transcarbamylase inhibitors and compositions containing them for tumor therapy

Info

Publication number: IL89287A
Authority: IL; Israel
Prior art keywords: compositions containing; acid derivatives; phosphonic acid; tumor therapy; aspartate transcarbamylase
Prior art date: 1988-02-16

Application number

IL89287A

Other languages

English (en)

Other versions

IL89287A0 (en

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-02-16

Filing date

1989-02-14

Publication date

1993-02-21

1989-02-14 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1989-09-10 Publication of IL89287A0 publication Critical patent/IL89287A0/xx

1993-02-21 Publication of IL89287A publication Critical patent/IL89287A/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

IL89287A 1988-02-16 1989-02-14 Halogenated phosphonic acid derivatives and aspartate transcarbamylase inhibitors and compositions containing them for tumor therapy IL89287A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP88400348A EP0328834A1 (en)	1988-02-16	1988-02-16	Novel aspartate transcarbamylase inhibitors

Publications (2)

Publication Number	Publication Date
IL89287A0 IL89287A0 (en)	1989-09-10
IL89287A true IL89287A (en)	1993-02-21

Family

ID=8200350

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL89287A IL89287A (en)	1988-02-16	1989-02-14	Halogenated phosphonic acid derivatives and aspartate transcarbamylase inhibitors and compositions containing them for tumor therapy

Country Status (12)

Country	Link
EP (2)	EP0328834A1 (pt)
JP (1)	JPH02149589A (pt)
CN (1)	CN1036207A (pt)
AU (1)	AU609942B2 (pt)
DK (1)	DK69489A (pt)
FI (1)	FI890695L (pt)
HU (1)	HUT49142A (pt)
IL (1)	IL89287A (pt)
NO (1)	NO890644L (pt)
NZ (1)	NZ227978A (pt)
PT (1)	PT89718B (pt)
ZA (1)	ZA891078B (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK0465297T3 (da) *	1990-07-04	1996-02-19	Merrell Pharma Inc	9-Purinylphosphonsyre-derivater
US5095007A (en) *	1990-10-24	1992-03-10	Ahluwalia Gurpreet S	Alteration of rate and character of hair growth
GB9200826D0 (en) *	1992-01-15	1992-03-11	Celltech Ltd	Peptidyl derivatives
CN115594579A (zh)	2016-09-14	2023-01-13	大金工业株式会社（Jp）	含支链含氟化合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3425701A1 (de) *	1984-07-12	1986-01-16	Bayer Ag, 5090 Leverkusen	Verfahren zur herstellung von chlorierten phosphorylmethylcarbonyl-derivaten und neue zwischenprodukte zu ihrer herstellung
FR2590259B1 (fr) *	1985-11-20	1989-05-12	Roussel Uclaf	Procede de preparation de derives fluores de l'acide phosphonique, et produits obtenus par la mise en oeuvre de ce procede
FR2596393B1 (fr) *	1986-04-01	1988-06-03	Sanofi Sa	Derives de l'acide hydroxy-3 dihydroxyoxophosphorio-4 butanoique, leur procede de preparation, leur application comme medicament et les compositions les renfermant

1988
- 1988-02-16 EP EP88400348A patent/EP0328834A1/en not_active Withdrawn
1989
- 1989-02-10 ZA ZA891078A patent/ZA891078B/xx unknown
- 1989-02-13 AU AU29904/89A patent/AU609942B2/en not_active Ceased
- 1989-02-14 IL IL89287A patent/IL89287A/xx not_active IP Right Cessation
- 1989-02-14 FI FI890695A patent/FI890695L/fi not_active Application Discontinuation
- 1989-02-14 NZ NZ227978A patent/NZ227978A/en unknown
- 1989-02-15 CN CN89100817A patent/CN1036207A/zh active Pending
- 1989-02-15 EP EP89400420A patent/EP0331550A1/en not_active Ceased
- 1989-02-15 PT PT89718A patent/PT89718B/pt not_active IP Right Cessation
- 1989-02-15 HU HU89767A patent/HUT49142A/hu unknown
- 1989-02-15 DK DK069489A patent/DK69489A/da not_active Application Discontinuation
- 1989-02-15 NO NO89890644A patent/NO890644L/no unknown
- 1989-02-16 JP JP1035199A patent/JPH02149589A/ja active Pending

Also Published As

Publication number	Publication date
EP0328834A1 (en)	1989-08-23
EP0331550A1 (en)	1989-09-06
PT89718A (pt)	1989-10-04
AU609942B2 (en)	1991-05-09
PT89718B (pt)	1994-03-31
IL89287A0 (en)	1989-09-10
NZ227978A (en)	1990-10-26
NO890644L (no)	1989-08-17
NO890644D0 (no)	1989-02-15
FI890695A0 (fi)	1989-02-14
DK69489A (da)	1989-08-17
HUT49142A (en)	1989-08-28
FI890695A7 (fi)	1989-08-17
JPH02149589A (ja)	1990-06-08
CN1036207A (zh)	1989-10-11
ZA891078B (en)	1989-10-25
DK69489D0 (da)	1989-02-15
AU2990489A (en)	1989-08-17
FI890695L (fi)	1989-08-17

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Legal Events

Date	Code	Title	Description
2005-07-25	MM9K	Patent not in force due to non-payment of renewal fees
2006-09-05	HC	Change of name of proprietor(s)	Owner name: AVENTIS INC. Free format text: FORMER NAME:MERRELL PHARMACEUTICALS INC.

Date

Code

Title

Description

2005-07-25

MM9K

Patent not in force due to non-payment of renewal fees

2006-09-05

Change of name of proprietor(s)

Owner name: AVENTIS INC.

Free format text: FORMER NAME:MERRELL PHARMACEUTICALS INC.