PT84680B - Processo para a preparacao de derivados de 1,5-benzotiazepina e de composicoes farmaceuticas que os contem - Google Patents
Processo para a preparacao de derivados de 1,5-benzotiazepina e de composicoes farmaceuticas que os contemInfo
- Publication number
- PT84680B PT84680B PT84680A PT8468087A PT84680B PT 84680 B PT84680 B PT 84680B PT 84680 A PT84680 A PT 84680A PT 8468087 A PT8468087 A PT 8468087A PT 84680 B PT84680 B PT 84680B
- Authority
- PT
- Portugal
- Prior art keywords
- derivatives
- benzotiazepine
- preparation
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
- KJFRSZASZNLCDF-UHFFFAOYSA-N 1,5-benzothiazepine Chemical class S1C=CC=NC2=CC=CC=C12 KJFRSZASZNLCDF-UHFFFAOYSA-N 0.000 abstract 1
- 229940127291 Calcium channel antagonist Drugs 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004817 pentamethylene group Chemical group [H]C([H])([*:2])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[*:1] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000000383 tetramethylene group Chemical group [H]C([H])([*:1])C([H])([H])C([H])([H])C([H])([H])[*:2] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/36—Seven-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/02—Seven-membered rings
- C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Diaphragms For Electromechanical Transducers (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8605346A FR2597097B1 (fr) | 1986-04-15 | 1986-04-15 | Derives de benzothiazepine-1, 5, leur preparation et leur application en therapeutique |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT84680A PT84680A (fr) | 1987-05-01 |
| PT84680B true PT84680B (pt) | 1989-12-29 |
Family
ID=9334233
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT84680A PT84680B (pt) | 1986-04-15 | 1987-04-14 | Processo para a preparacao de derivados de 1,5-benzotiazepina e de composicoes farmaceuticas que os contem |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4743599A (pt) |
| EP (1) | EP0242265B1 (pt) |
| JP (1) | JPS62242674A (pt) |
| KR (1) | KR870010029A (pt) |
| AT (1) | ATE63908T1 (pt) |
| AU (1) | AU586086B2 (pt) |
| CA (1) | CA1283657C (pt) |
| DE (1) | DE3770321D1 (pt) |
| DK (1) | DK191587A (pt) |
| ES (1) | ES2029845T3 (pt) |
| FI (1) | FI871637A7 (pt) |
| FR (1) | FR2597097B1 (pt) |
| GR (1) | GR3002225T3 (pt) |
| HU (1) | HU196776B (pt) |
| IL (1) | IL82181A0 (pt) |
| NO (1) | NO167286C (pt) |
| PT (1) | PT84680B (pt) |
| ZA (1) | ZA872683B (pt) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2703564B2 (ja) * | 1987-07-31 | 1998-01-26 | 田辺製薬株式会社 | １，５−ベンゾチアゼピン誘導体 |
| FR2621584B1 (fr) * | 1987-10-07 | 1991-05-24 | Synthelabo | Derives de benzothiazepine-1,5, leur preparation et leur application en therapeutique |
| FR2630109B1 (fr) * | 1988-04-19 | 1991-11-29 | Synthelabo | Derives de ((n-(amino-2 oxo-2 ethyl)methylamino)-2 ethyl)-5 hydroxy-3 (methoxy-4 phenyl)-2 dihydro-2,3 5h-benzothiazepine-1,5 one-4, leur preparation et leur application en therapeutique |
| US4902684A (en) * | 1988-06-20 | 1990-02-20 | E. R. Squibb & Sons, Inc. | Benzazepine and benzothiazepine derivatives |
| JP2863534B2 (ja) * | 1988-10-24 | 1999-03-03 | マリオン ラボラトリーズ，インコーポレイティド | 医薬組成物 |
| US4952692A (en) * | 1989-04-04 | 1990-08-28 | E. R. Squibb & Sons, Inc. | Benzazepine derivatives |
| FR2669632B1 (fr) * | 1990-11-22 | 1993-01-15 | Synthelabo | Derives de benzo-1, 5-thiazepine, leur preparation et leur application en therapeutique. |
| FR2672599B1 (fr) * | 1991-02-08 | 1994-11-18 | Synthelabo | Derives de benzothiazepine-1,5, leur preparation et leur application en therapeutique. |
| US5580867A (en) * | 1994-09-09 | 1996-12-03 | Universite De Montreal | Myocardial protection during ischemia and reperfusion |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3341519A (en) * | 1965-04-28 | 1967-09-12 | Squibb & Sons Inc | Novel benzoxazines, benzothiazines, benzoxazepins and benzothiazepins |
| US3562257A (en) * | 1967-10-28 | 1971-02-09 | Tanabe Seiyaku Co | Benzothiazepine derivatives |
-
1986
- 1986-04-15 FR FR8605346A patent/FR2597097B1/fr not_active Expired
-
1987
- 1987-04-06 DE DE8787400750T patent/DE3770321D1/de not_active Expired - Fee Related
- 1987-04-06 EP EP87400750A patent/EP0242265B1/fr not_active Expired - Lifetime
- 1987-04-06 ES ES198787400750T patent/ES2029845T3/es not_active Expired - Lifetime
- 1987-04-06 AT AT87400750T patent/ATE63908T1/de not_active IP Right Cessation
- 1987-04-10 IL IL82181A patent/IL82181A0/xx not_active IP Right Cessation
- 1987-04-14 DK DK191587A patent/DK191587A/da not_active Application Discontinuation
- 1987-04-14 KR KR870003554A patent/KR870010029A/ko not_active Withdrawn
- 1987-04-14 US US07/038,152 patent/US4743599A/en not_active Expired - Fee Related
- 1987-04-14 CA CA000534703A patent/CA1283657C/en not_active Expired - Fee Related
- 1987-04-14 FI FI871637A patent/FI871637A7/fi not_active Application Discontinuation
- 1987-04-14 ZA ZA872683A patent/ZA872683B/xx unknown
- 1987-04-14 HU HU871643A patent/HU196776B/hu not_active IP Right Cessation
- 1987-04-14 JP JP62091833A patent/JPS62242674A/ja active Pending
- 1987-04-14 PT PT84680A patent/PT84680B/pt not_active IP Right Cessation
- 1987-04-14 NO NO871575A patent/NO167286C/no unknown
- 1987-04-15 AU AU71564/87A patent/AU586086B2/en not_active Ceased
-
1991
- 1991-07-02 GR GR91400920T patent/GR3002225T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO167286B (no) | 1991-07-15 |
| NO871575D0 (no) | 1987-04-14 |
| DK191587A (da) | 1987-10-16 |
| FR2597097B1 (fr) | 1988-12-02 |
| US4743599A (en) | 1988-05-10 |
| ATE63908T1 (de) | 1991-06-15 |
| NO871575L (no) | 1987-10-16 |
| DK191587D0 (da) | 1987-04-14 |
| PT84680A (fr) | 1987-05-01 |
| EP0242265A1 (fr) | 1987-10-21 |
| ZA872683B (en) | 1987-11-25 |
| CA1283657C (en) | 1991-04-30 |
| KR870010029A (ko) | 1987-11-30 |
| AU7156487A (en) | 1987-10-22 |
| NO167286C (no) | 1991-10-23 |
| FR2597097A1 (fr) | 1987-10-16 |
| DE3770321D1 (de) | 1991-07-04 |
| HUT45518A (en) | 1988-07-28 |
| GR3002225T3 (en) | 1992-12-30 |
| IL82181A0 (en) | 1987-10-30 |
| AU586086B2 (en) | 1989-06-29 |
| JPS62242674A (ja) | 1987-10-23 |
| EP0242265B1 (fr) | 1991-05-29 |
| FI871637A0 (fi) | 1987-04-14 |
| FI871637A7 (fi) | 1987-10-16 |
| ES2029845T3 (es) | 1992-10-01 |
| HU196776B (en) | 1989-01-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PT78682A (pt) | Processo para a preparacao de novos derivados de 8-cloro-1,5-benzotiazepina e de composicoes farmaceuticas que os contem | |
| PT92806A (pt) | Processo para a preparacao de derivados de 2-amino-pirimidinona e de composicoes farmaceuticas que os contem | |
| PT83647B (pt) | Processo para a preparacao de novos derivados de benzimidazole com actividade farmacologica e de composicoes farmaceuticas que os contem | |
| ES520987A0 (es) | Procedimiento para la preparacion de derivados de acido espiro (4.(3+n))-2-aza-3carboxilico. | |
| ES552593A0 (es) | Un procedimiento para preparar derivados de aminoacidos | |
| PT91364A (pt) | Processo para a preparacao de derivados de 3-piperazinil-benzazol e de composicoes farmaceuticas que os contem | |
| JPS646243A (en) | Glycerin derivative | |
| PT83535B (pt) | Processo para a preparacao de composicoes farmaceuticas contendo derivados de aminoacidos | |
| PT96030A (pt) | Processo para a preparacao de aminocarbonilcarbamatos relacionados com fisoestigmina e de composicoes farmaceuticas que os contem | |
| PT84680B (pt) | Processo para a preparacao de derivados de 1,5-benzotiazepina e de composicoes farmaceuticas que os contem | |
| PT82512B (pt) | Processo para a preparacao de derivados de quinolilglicinamidas com actividade psicotropica e de composicoes farmaceuticas que os contem | |
| DK527984A (da) | 11-substituerede 5h,11h-pyrrolo(2,1-c)(1,4)benzoxazepiner eller farmaceutisk acceptable salte deraf, deres fremstilling og mellemprodukter hertil samt deres anvendelse som antipsychotika og analgetika | |
| PT91203A (pt) | Processo para a preparacao de novos derivados de antibioticos bu-3608 e de composicoes farmaceuticas que os contem | |
| PT81229B (pt) | Processo para a preparacao de 1,3-dimetil-1h-purino-2,6-dionas contendo 1h-indol-3-ilo e de composicoes farmaceuticas contendo estes compostos | |
| ES556351A0 (es) | Un procedimiento para preparar derivados de pirrolidona | |
| PT97286A (pt) | Processo para a preparacao de novos derivados do 3-aminocromano e de composicoes farmaceuticas que os contem | |
| PT88088A (pt) | Processo para a preparacao de derivados de piperidina e de composicoes farmaceuticas que os contem | |
| PT81206B (pt) | Processo para a preparacao de derivados de furo {3,2-c} piridinas e de composicoes farmaceuticas que os contem | |
| PT82814B (pt) | Processo de preparacao de derivados de 5-oxo-1-imidazolidinoacetimida, dos seus sais farmaceuticamente aceitaveis e das composicoes farmaceuticas que os contem | |
| PT82175B (pt) | Processo para preparacao de novos derivados de 3-piridilmetilnaftalina e de composicoes farmceuticas que os contem | |
| SE8303719L (sv) | Eburnan-oximderivat, forfarande for framstellning derav samt farmaceutiska kompositioner innehallande dessa foreningar | |
| HK64691A (en) | Anticonvulsant agents | |
| ES8500923A1 (es) | Procedimiento para la preparacion de derivados de acido fenilacetico | |
| PT81314B (pt) | Processo para a obtencao de derivados de tiadiazole activos sobre o sistema nervoso central | |
| PT95881A (pt) | Processo para a preparacao de derivados de pradimicina com accao anti-fungica e de composicoes farmaceuticas que os contem |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19921231 |