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PT77122B - Procede de preparation de derives de l'acide methylenediphosphonique - Google Patents

Procede de preparation de derives de l'acide methylenediphosphonique

Info

Publication number
PT77122B
PT77122B PT77122A PT7712283A PT77122B PT 77122 B PT77122 B PT 77122B PT 77122 A PT77122 A PT 77122A PT 7712283 A PT7712283 A PT 7712283A PT 77122 B PT77122 B PT 77122B
Authority
PT
Portugal
Prior art keywords
preparation
acid derivatives
methylenediphosphonic acid
methylenediphosphonic
derivatives
Prior art date
Application number
PT77122A
Other languages
English (en)
French (fr)
Other versions
PT77122A (fr
Inventor
Jean-Claude Breliere
Xavier Emonds-Alt
Georges Garcia
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of PT77122A publication Critical patent/PT77122A/pt
Publication of PT77122B publication Critical patent/PT77122B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6536—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and sulfur atoms with or without oxygen atoms, as the only ring hetero atoms
    • C07F9/6539—Five-membered rings
    • C07F9/6541—Five-membered rings condensed with carbocyclic rings or carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3839—Polyphosphonic acids
    • C07F9/3865—Polyphosphonic acids containing sulfur substituents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4025—Esters of poly(thio)phosphonic acids
    • C07F9/4043—Esters of poly(thio)phosphonic acids containing sulfur substituents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576—Six-membered rings
    • C07F9/58—Pyridine rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6503—Five-membered rings
    • C07F9/6506—Five-membered rings having the nitrogen atoms in positions 1 and 3
    • C07F9/65068—Five-membered rings having the nitrogen atoms in positions 1 and 3 condensed with carbocyclic rings or carbocyclic ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509—Six-membered rings
    • C07F9/6512—Six-membered rings having the nitrogen atoms in positions 1 and 3
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PT77122A 1982-07-29 1983-07-28 Procede de preparation de derives de l'acide methylenediphosphonique PT77122B (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8213250A FR2531088B1 (fr) 1982-07-29 1982-07-29 Produits anti-inflammatoires derives de l'acide methylenediphosphonique et leur procede de preparation

Publications (2)

Publication Number Publication Date
PT77122A PT77122A (fr) 1983-08-01
PT77122B true PT77122B (fr) 1986-01-24

Family

ID=9276447

Family Applications (1)

Application Number Title Priority Date Filing Date
PT77122A PT77122B (fr) 1982-07-29 1983-07-28 Procede de preparation de derives de l'acide methylenediphosphonique

Country Status (35)

Country Link
US (2) US4746654A (pt)
EP (1) EP0100718B1 (pt)
JP (1) JPS5942395A (pt)
KR (1) KR910000726B1 (pt)
AR (2) AR242393A1 (pt)
AT (1) ATE30235T1 (pt)
AU (1) AU566880B2 (pt)
CA (1) CA1267650A (pt)
CS (1) CS252463B2 (pt)
CZ (1) CZ419191A3 (pt)
DD (1) DD213670A5 (pt)
DE (1) DE3374062D1 (pt)
DK (1) DK170342B1 (pt)
DZ (1) DZ562A1 (pt)
EG (1) EG15968A (pt)
ES (1) ES8403923A1 (pt)
FI (1) FI75830C (pt)
FR (1) FR2531088B1 (pt)
GR (1) GR79597B (pt)
HU (1) HU190454B (pt)
IE (1) IE56343B1 (pt)
IL (1) IL69347A (pt)
LU (1) LU88723I2 (pt)
MA (1) MA19858A1 (pt)
NL (1) NL960007I2 (pt)
NO (2) NO164712C (pt)
NZ (1) NZ205061A (pt)
OA (1) OA07507A (pt)
PH (1) PH22082A (pt)
PL (2) PL141316B1 (pt)
PT (1) PT77122B (pt)
SG (1) SG18588G (pt)
SU (2) SU1333240A3 (pt)
YU (1) YU45143B (pt)
ZA (1) ZA835578B (pt)

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* Cited by examiner, † Cited by third party
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ES524495A0 (es) 1984-04-16
MA19858A1 (fr) 1984-04-01
FI75830C (fi) 1988-08-08
EG15968A (en) 1989-01-30
SG18588G (en) 1988-09-30
PL243229A1 (en) 1984-07-16
KR840005459A (ko) 1984-11-12
DD213670A5 (de) 1984-09-19
PL142022B1 (en) 1987-09-30
NO164712B (no) 1990-07-30
NO164712C (no) 1990-11-07
AR242394A1 (es) 1993-03-31
LU88723I2 (fr) 1996-08-23
OA07507A (fr) 1985-03-31
CS252463B2 (en) 1987-09-17
CS568883A2 (en) 1987-01-15
ZA835578B (en) 1984-04-25
AU1732483A (en) 1984-02-02
HU190454B (en) 1986-09-29
DK336783D0 (da) 1983-07-22
GR79597B (pt) 1984-10-31
EP0100718B1 (fr) 1987-10-14
SU1367859A3 (ru) 1988-01-15
NZ205061A (en) 1987-08-31
CZ419191A3 (en) 1993-10-13
PL141316B1 (en) 1987-07-31
FI832758A0 (fi) 1983-07-29
PT77122A (fr) 1983-08-01
SU1333240A3 (ru) 1987-08-23
FI75830B (fi) 1988-04-29
AR242393A1 (es) 1993-03-31
NO832701L (no) 1984-01-30
JPS5942395A (ja) 1984-03-08
IL69347A (en) 1987-02-27
FI832758L (fi) 1984-01-30
YU45143B (en) 1992-03-10
NL960007I1 (nl) 1996-09-02
AU566880B2 (en) 1987-11-05
FR2531088A1 (fr) 1984-02-03
US4746654A (en) 1988-05-24
DK170342B1 (da) 1995-08-07
ES8403923A1 (es) 1984-04-16
DK336783A (da) 1984-01-30
US4876248A (en) 1989-10-24
ATE30235T1 (de) 1987-10-15
FR2531088B1 (fr) 1987-08-28
JPH0429676B2 (pt) 1992-05-19
IE56343B1 (en) 1991-07-03
CA1267650A (en) 1990-04-10
KR910000726B1 (ko) 1991-01-31
PH22082A (en) 1988-05-20
DZ562A1 (fr) 2004-09-13
EP0100718A1 (fr) 1984-02-15
NL960007I2 (nl) 1997-03-03
IE831716L (en) 1984-01-29
YU160083A (en) 1986-08-31
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IL69347A0 (en) 1983-11-30
DE3374062D1 (en) 1987-11-19

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