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PT4313945T - Sal de hidrobrometo cristalino de 5-meo-dmt - Google Patents

Sal de hidrobrometo cristalino de 5-meo-dmt

Info

Publication number
PT4313945T
PT4313945T PT237170469T PT23717046T PT4313945T PT 4313945 T PT4313945 T PT 4313945T PT 237170469 T PT237170469 T PT 237170469T PT 23717046 T PT23717046 T PT 23717046T PT 4313945 T PT4313945 T PT 4313945T
Authority
PT
Portugal
Prior art keywords
dmt
meo
hydrobromide salt
crystalline hydrobromide
crystalline
Prior art date
Application number
PT237170469T
Other languages
English (en)
Original Assignee
Gh Res Ireland Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=80978907&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT4313945(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gh Res Ireland Limited filed Critical Gh Res Ireland Limited
Publication of PT4313945T publication Critical patent/PT4313945T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16Tryptamines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/4045Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Addiction (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT237170469T 2022-03-27 2023-03-27 Sal de hidrobrometo cristalino de 5-meo-dmt PT4313945T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP22000081 2022-03-27

Publications (1)

Publication Number Publication Date
PT4313945T true PT4313945T (pt) 2024-06-11

Family

ID=80978907

Family Applications (1)

Application Number Title Priority Date Filing Date
PT237170469T PT4313945T (pt) 2022-03-27 2023-03-27 Sal de hidrobrometo cristalino de 5-meo-dmt

Country Status (19)

Country Link
US (2) US12172960B2 (pt)
EP (2) EP4313945B1 (pt)
JP (1) JP2025510292A (pt)
KR (1) KR20240167881A (pt)
CN (1) CN118974015A (pt)
AU (1) AU2023246775A1 (pt)
DK (1) DK4313945T3 (pt)
ES (1) ES2982834T3 (pt)
FI (1) FI4313945T3 (pt)
HR (1) HRP20240574T1 (pt)
HU (1) HUE067428T2 (pt)
IL (1) IL315889A (pt)
LT (1) LT4313945T (pt)
PL (1) PL4313945T3 (pt)
PT (1) PT4313945T (pt)
RS (1) RS65585B1 (pt)
SI (1) SI4313945T1 (pt)
SM (1) SMT202400196T1 (pt)
WO (1) WO2023186834A1 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4155306A1 (en) 2021-01-15 2023-03-29 Beckley Psytech Limited Neuroactive ergoline analogue
US12264131B2 (en) 2022-08-19 2025-04-01 Beckley Psytech Limited Pharmaceutically acceptable salts and compositions thereof
GB202308830D0 (en) 2023-06-13 2023-07-26 Beckley Psytech Ltd 5-methoxy-n,n-dimethyltryptamine (5-meo-dmt) formulations
US12246005B2 (en) 2023-06-13 2025-03-11 Beckley Psytech Limited 5-methoxy-n,n-dimethyltryptamine (5-MeO-DMT) formulations

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220071958A1 (en) 2019-02-22 2022-03-10 GH Research Ireland Limited 5-methoxy-n,n-dimethyltryptamine (5-meo-dmt) for treating depression
EP4464377A3 (en) 2019-02-22 2025-02-26 GH Research Ireland Limited Compositions comprising 5-methoxy-n,n-dimethyltryptamine (5-meo-dmt) for use in treating mental disorders
EP3753923A1 (en) 2019-06-19 2020-12-23 GH Research Limited Recrystallisation of 5-methoxy-n,n-dimethyltryptamine (5-meo-dmt) in methyl tert.-butyl ether (mtbe) without adding an anti-solvent
EP4595962A3 (en) 2020-06-12 2025-10-22 Beckley Psytech Limited Pharmaceutical composition
IL310296A (en) * 2021-07-22 2024-03-01 Gh Res Ireland Limited A method for the preparation of a tryptamine derivative
US11697638B2 (en) 2021-09-08 2023-07-11 Small Pharma Ltd 5-methoxy-N,N-dimethyltryptamine crystalline forms
US12264131B2 (en) 2022-08-19 2025-04-01 Beckley Psytech Limited Pharmaceutically acceptable salts and compositions thereof
GB202212116D0 (en) 2022-08-19 2022-10-05 Beckley Psytech Ltd Pharmaceutically acceptable salts and Compositions thereof

Also Published As

Publication number Publication date
JP2025510292A (ja) 2025-04-14
LT4313945T (lt) 2024-08-26
CN118974015A (zh) 2024-11-15
EP4313945A1 (en) 2024-02-07
SMT202400196T1 (it) 2024-07-09
KR20240167881A (ko) 2024-11-28
ES2982834T3 (es) 2024-10-17
HRP20240574T1 (hr) 2024-09-27
FI4313945T3 (fi) 2024-05-23
IL315889A (en) 2024-11-01
RS65585B1 (sr) 2024-06-28
US20240228440A1 (en) 2024-07-11
PL4313945T3 (pl) 2024-08-19
US20250188029A1 (en) 2025-06-12
EP4530283A1 (en) 2025-04-02
WO2023186834A1 (en) 2023-10-05
DK4313945T3 (da) 2024-05-06
SI4313945T1 (sl) 2024-10-30
HUE067428T2 (hu) 2024-10-28
AU2023246775A1 (en) 2024-11-07
US12172960B2 (en) 2024-12-24
EP4313945B1 (en) 2024-03-13

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