PT3849970T - R)-5-carbamoilpiridin-3-il-2-metil-4-(3-(trifluorometoxi)benzil)piperazina-1-carboxilato, composições e métodos de utilização das mesmas - Google Patents

R)-5-carbamoilpiridin-3-il-2-metil-4-(3-(trifluorometoxi)benzil)piperazina-1-carboxilato, composições e métodos de utilização das mesmas

Info

Publication number: PT3849970T
Authority: PT; Portugal
Prior art keywords: carbamoylpyridin; trifluoromethoxy; piperazine; carboxylate; benzyl
Prior art date: 2018-09-13

Application number

PT197787211T

Other languages

English (en)

Original Assignee

Lundbeck La Jolla Research Center Inc

Celgene Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2018-09-13

Filing date

2019-09-12

Publication date

2024-09-25

2019-09-12 Application filed by Lundbeck La Jolla Research Center Inc, Celgene Corp filed Critical Lundbeck La Jolla Research Center Inc

2024-09-25 Publication of PT3849970T publication Critical patent/PT3849970T/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
- C07D211/94—Oxygen atom, e.g. piperidine N-oxide
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Epidemiology (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

PT197787211T 2018-09-13 2019-09-12 R)-5-carbamoilpiridin-3-il-2-metil-4-(3-(trifluorometoxi)benzil)piperazina-1-carboxilato, composições e métodos de utilização das mesmas PT3849970T (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US201862731014P	2018-09-13	2018-09-13

Publications (1)

Publication Number	Publication Date
PT3849970T true PT3849970T (pt)	2024-09-25

Family

ID=68069873

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT197787211T PT3849970T (pt)	2018-09-13	2019-09-12	R)-5-carbamoilpiridin-3-il-2-metil-4-(3-(trifluorometoxi)benzil)piperazina-1-carboxilato, composições e métodos de utilização das mesmas

Country Status (28)

Country	Link
US (3)	US11053199B2 (pt)
EP (2)	EP4434583A3 (pt)
JP (1)	JP7405840B2 (pt)
KR (1)	KR102844245B1 (pt)
CN (3)	CN113227069B (pt)
AU (1)	AU2019337623B2 (pt)
BR (1)	BR112021004340A2 (pt)
CA (1)	CA3112200A1 (pt)
CL (1)	CL2021000596A1 (pt)
CO (1)	CO2021003295A2 (pt)
DK (1)	DK3849970T3 (pt)
EA (1)	EA202190511A1 (pt)
ES (1)	ES2993173T3 (pt)
FI (1)	FI3849970T3 (pt)
HR (1)	HRP20241294T1 (pt)
HU (1)	HUE068147T2 (pt)
IL (1)	IL281276B2 (pt)
LT (1)	LT3849970T (pt)
MA (1)	MA53607B1 (pt)
MX (1)	MX2021002923A (pt)
MY (2)	MY208901A (pt)
PL (1)	PL3849970T3 (pt)
PT (1)	PT3849970T (pt)
RS (1)	RS65967B1 (pt)
SG (1)	SG11202102143RA (pt)
SI (1)	SI3849970T1 (pt)
SM (1)	SMT202400369T1 (pt)
WO (1)	WO2020056105A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PL3849970T3 (pl)	2018-09-13	2025-01-07	Celgene Corporation	Krystaliczny (r)-5-karbamoilopirydyn-3-ylo-2-metylo-4-(3-(trifluorometoksy)benzylo)piperazyno-1-karboksylan, kompozycje i sposoby ich zastosowania

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP2607362B1 (en) *	2005-02-17	2014-12-31	Astellas Pharma Inc.	Piperidine and piperazine carboxylates as FAAH inhibitors
JP2017505777A (ja) *	2014-01-29	2017-02-23	シンタファーマスーティカルズコーポレーション	標的化治療薬
EA201991898A1 (ru) *	2017-03-13	2020-02-07	Эбайд Терапьютикс, Инк.	Двойные ингибиторы magl и faah
PL3849970T3 (pl) *	2018-09-13	2025-01-07	Celgene Corporation	Krystaliczny (r)-5-karbamoilopirydyn-3-ylo-2-metylo-4-(3-(trifluorometoksy)benzylo)piperazyno-1-karboksylan, kompozycje i sposoby ich zastosowania

2019
- 2019-09-12 PL PL19778721.1T patent/PL3849970T3/pl unknown
- 2019-09-12 CN CN201980060119.9A patent/CN113227069B/zh active Active
- 2019-09-12 MY MYPI2021001295A patent/MY208901A/en unknown
- 2019-09-12 ES ES19778721T patent/ES2993173T3/es active Active
- 2019-09-12 MY MYPI2024007477A patent/MY210363A/en unknown
- 2019-09-12 KR KR1020217010747A patent/KR102844245B1/ko active Active
- 2019-09-12 MA MA53607A patent/MA53607B1/fr unknown
- 2019-09-12 EA EA202190511A patent/EA202190511A1/ru unknown
- 2019-09-12 FI FIEP19778721.1T patent/FI3849970T3/fi active
- 2019-09-12 PT PT197787211T patent/PT3849970T/pt unknown
- 2019-09-12 BR BR112021004340-3A patent/BR112021004340A2/pt unknown
- 2019-09-12 HR HRP20241294TT patent/HRP20241294T1/hr unknown
- 2019-09-12 US US16/569,578 patent/US11053199B2/en active Active
- 2019-09-12 DK DK19778721.1T patent/DK3849970T3/da active
- 2019-09-12 AU AU2019337623A patent/AU2019337623B2/en active Active
- 2019-09-12 HU HUE19778721A patent/HUE068147T2/hu unknown
- 2019-09-12 EP EP24185102.1A patent/EP4434583A3/en active Pending
- 2019-09-12 SG SG11202102143RA patent/SG11202102143RA/en unknown
- 2019-09-12 LT LTEPPCT/US2019/050771T patent/LT3849970T/lt unknown
- 2019-09-12 CA CA3112200A patent/CA3112200A1/en active Pending
- 2019-09-12 JP JP2021514123A patent/JP7405840B2/ja active Active
- 2019-09-12 RS RS20241039A patent/RS65967B1/sr unknown
- 2019-09-12 MX MX2021002923A patent/MX2021002923A/es unknown
- 2019-09-12 SM SM20240369T patent/SMT202400369T1/it unknown
- 2019-09-12 SI SI201930824T patent/SI3849970T1/sl unknown
- 2019-09-12 WO PCT/US2019/050771 patent/WO2020056105A1/en not_active Ceased
- 2019-09-12 EP EP19778721.1A patent/EP3849970B1/en active Active
- 2019-09-12 IL IL281276A patent/IL281276B2/en unknown
- 2019-09-12 CN CN202410683444.3A patent/CN118530218A/zh active Pending
- 2019-09-12 CN CN202410683425.0A patent/CN118561814A/zh active Pending
2021
- 2021-03-10 CL CL2021000596A patent/CL2021000596A1/es unknown
- 2021-03-12 CO CONC2021/0003295A patent/CO2021003295A2/es unknown
- 2021-06-03 US US17/338,182 patent/US11680046B2/en active Active
2023
- 2023-05-05 US US18/143,765 patent/US12410133B2/en active Active

Also Published As

Publication number	Publication date
MY208901A (en)	2025-06-09
EP3849970A1 (en)	2021-07-21
JP7405840B2 (ja)	2023-12-26
CN113227069A (zh)	2021-08-06
AU2019337623A1 (en)	2021-05-13
FI3849970T3 (fi)	2024-09-20
AU2019337623B2 (en)	2024-12-05
DK3849970T3 (da)	2024-09-30
US20230382861A1 (en)	2023-11-30
RS65967B1 (sr)	2024-10-31
US20200095201A1 (en)	2020-03-26
MX2021002923A (es)	2021-09-08
US11053199B2 (en)	2021-07-06
LT3849970T (lt)	2024-10-10
SI3849970T1 (sl)	2024-11-29
US20210363105A1 (en)	2021-11-25
CA3112200A1 (en)	2020-03-19
IL281276B1 (en)	2024-09-01
JP2022500441A (ja)	2022-01-04
EP4434583A3 (en)	2024-11-20
SG11202102143RA (en)	2021-04-29
EA202190511A1 (ru)	2021-07-05
MY210363A (en)	2025-09-13
US11680046B2 (en)	2023-06-20
CO2021003295A2 (es)	2021-07-30
CN113227069B (zh)	2024-11-05
EP3849970B1 (en)	2024-07-03
CN118561814A (zh)	2024-08-30
US12410133B2 (en)	2025-09-09
SMT202400369T1 (it)	2024-11-15
CN118530218A (zh)	2024-08-23
IL281276A (en)	2021-04-29
WO2020056105A9 (en)	2020-05-28
CL2021000596A1 (es)	2021-07-30
HRP20241294T1 (hr)	2024-12-06
WO2020056105A1 (en)	2020-03-19
MA53607A (fr)	2021-12-22
KR102844245B1 (ko)	2025-08-11
IL281276B2 (en)	2025-01-01
BR112021004340A2 (pt)	2021-05-25
HUE068147T2 (hu)	2024-12-28
MA53607B1 (fr)	2025-05-30
PL3849970T3 (pl)	2025-01-07
KR20210057789A (ko)	2021-05-21
EP4434583A2 (en)	2024-09-25
ES2993173T3 (en)	2024-12-23

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