PT3266446T - Composição oftálmica compreendendo óleo de rícino e triglicérido de cadeia média - Google Patents
Composição oftálmica compreendendo óleo de rícino e triglicérido de cadeia médiaInfo
- Publication number
- PT3266446T PT3266446T PT16382321T PT16382321T PT3266446T PT 3266446 T PT3266446 T PT 3266446T PT 16382321 T PT16382321 T PT 16382321T PT 16382321 T PT16382321 T PT 16382321T PT 3266446 T PT3266446 T PT 3266446T
- Authority
- PT
- Portugal
- Prior art keywords
- castor oil
- medium chain
- ophthalmic composition
- chain triglyceride
- triglyceride
- Prior art date
Links
- 239000004359 castor oil Substances 0.000 title 1
- 235000019438 castor oil Nutrition 0.000 title 1
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 title 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/45—Ericaceae or Vacciniaceae (Heath or Blueberry family), e.g. blueberry, cranberry or bilberry
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6905—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
- A61K47/6907—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a microemulsion, nanoemulsion or micelle
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Ophthalmology & Optometry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dispersion Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Mycology (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Nanotechnology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16382321.4A EP3266446B1 (en) | 2016-07-07 | 2016-07-07 | Ophthalmic composition comprising castor oil and medium chain triglyceride |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3266446T true PT3266446T (pt) | 2019-01-30 |
Family
ID=56404062
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT16382321T PT3266446T (pt) | 2016-07-07 | 2016-07-07 | Composição oftálmica compreendendo óleo de rícino e triglicérido de cadeia média |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US10660848B2 (pt) |
| EP (1) | EP3266446B1 (pt) |
| JP (1) | JP7224095B2 (pt) |
| CN (1) | CN107582605A (pt) |
| DK (1) | DK3266446T3 (pt) |
| ES (1) | ES2706535T3 (pt) |
| HR (1) | HRP20190036T1 (pt) |
| JO (1) | JOP20170147B1 (pt) |
| LT (1) | LT3266446T (pt) |
| PL (1) | PL3266446T3 (pt) |
| PT (1) | PT3266446T (pt) |
| RS (1) | RS58292B1 (pt) |
| RU (1) | RU2756758C2 (pt) |
| SI (1) | SI3266446T1 (pt) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3500344A4 (en) | 2016-08-19 | 2020-08-05 | Akrivista, LLC | METHODS OF DIAGNOSIS AND TREATMENT OF DRY EYE SYNDROME AND COMPOSITIONS FOR TREATMENT OF A HUMAN EYE |
| KR101892865B1 (ko) * | 2017-08-16 | 2018-08-28 | 계명대학교 산학협력단 | 마퀴베리를 유효성분으로 함유하는 아토피성 피부염 예방 또는 치료용 조성물 |
| CA3072494A1 (en) | 2017-08-18 | 2019-02-21 | Akrivista, LLC | Methods of diagnosing and treating dry eye syndrome and compositions for treating a human eye |
| AU2019206492B2 (en) | 2018-01-12 | 2025-01-09 | Metimedi Pharmaceuticals Co., Ltd. | Methods of treating chronic inflammatory diseases |
| KR102556874B1 (ko) * | 2018-02-14 | 2023-07-18 | 동국제약 주식회사 | 비스포스포네이트 및 콜레칼시페롤을 함유하는 경구용 에멀젼 조성물 및 그 제조방법 |
| BR112020017661A2 (pt) * | 2018-02-28 | 2020-12-22 | Santen Pharmaceutical Co., Ltd. | Composição oftálmica compreendendo diquafosol e polímero catiônico |
| CA3110287A1 (en) * | 2018-08-28 | 2020-03-05 | Cloudbreak Therapeutics, Llc | Emulsion formulations of multikinase inhibitors |
| JP2020075918A (ja) * | 2018-11-02 | 2020-05-21 | 千寿製薬株式会社 | 角膜上皮創傷治癒促進用の眼科用組成物 |
| CA3122359A1 (en) * | 2018-12-06 | 2020-06-11 | Lipicare Life Sciences Ltd. | Vitamin d micro-emulsions and uses thereof |
| CA3120453A1 (en) * | 2018-12-10 | 2020-06-18 | EternaTear, Inc. | Ophthalmic formulations providing durable ocular lubrication |
| CN113286581A (zh) * | 2019-01-09 | 2021-08-20 | 扶桑药品工业株式会社 | 用于治疗视网膜疾病的眼内或者口服给药用药物组合物 |
| CA3134362A1 (en) * | 2019-04-22 | 2020-10-29 | Hampar L. Karageozian | Compositions and methods useable for treatment of dry eye |
| IT201900007202A1 (it) * | 2019-05-24 | 2020-11-24 | Pavia Farm S R L | Composizione a base di vitamine liposolubili ad elevato assorbimento enterico |
| RU2706703C1 (ru) * | 2019-08-19 | 2019-11-20 | Общество с ограниченной ответственностью "ПРОФИТ ФАРМ" | Раствор увлажняющий офтальмологический |
| GB202010829D0 (en) * | 2020-07-14 | 2020-08-26 | Exonate Ltd | Compounds for treatment of neovascular diseases |
| CN111973554A (zh) * | 2020-09-03 | 2020-11-24 | 浙江目中明生物科技有限公司 | 一种护眼水 |
| US11951123B2 (en) | 2022-01-12 | 2024-04-09 | Platform Ophthalmic Innovations, LLC | Fortified nutritional lubricating drops for dry eye disease |
| US12397017B2 (en) | 2022-01-12 | 2025-08-26 | Platform Ophthalmic Innovations, LLC | Fortified nutritional lubricating drops for dry eye disease |
| US11679078B1 (en) | 2022-03-08 | 2023-06-20 | EternaTear, Inc. | Ophthalmic formulations and related methods |
| US11471475B1 (en) | 2022-03-08 | 2022-10-18 | Ralph P. Stone | Ophthalmic suspension vehicles and related methods for pharmaceutical ingredient delivery |
| CN115887356B (zh) * | 2022-11-21 | 2025-06-27 | 山东诺明康药物研究院有限公司 | 一种地夸磷索钠离子敏感型凝胶剂及其制备方法 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3102593A1 (de) * | 1981-01-27 | 1982-09-02 | Dr. Thilo & Co GmbH, 8021 Sauerlach | Arzneimittelzubereitung zur anwendung am auge |
| JP3410364B2 (ja) * | 1997-05-14 | 2003-05-26 | 千寿製薬株式会社 | ジフルプレドナート含有組成物 |
| WO1998053806A1 (en) * | 1997-05-26 | 1998-12-03 | New Vision Co., Ltd. | Medicinal compositions for topical administration containing vitamin d and vitamin k |
| US5981607A (en) * | 1998-01-20 | 1999-11-09 | Allergan | Emulsion eye drop for alleviation of dry eye related symptoms in dry eye patients and/or contact lens wearers |
| FR2823441B1 (fr) * | 2001-04-12 | 2004-09-10 | Thea Lab | Composition pharmaceutique a base de macrolides pour application locale en ophtalmologie et son procede de preparation |
| WO2004098592A1 (ja) * | 2003-05-06 | 2004-11-18 | Senju Pharmaceutical Co. Ltd. | オキサゾリジノン誘導体含有組成物 |
| EP1655021B1 (en) * | 2004-11-09 | 2008-10-29 | Novagali Pharma SA | Oil-in-water type emulsion with low concentration of cationic agent and positive zeta potential |
| CN100478025C (zh) * | 2005-03-25 | 2009-04-15 | 中国科学院上海药物研究所 | 一种环孢菌素a眼用微乳制剂及其制备方法 |
| WO2008035246A2 (en) * | 2006-07-28 | 2008-03-27 | Novagali Pharma Sa | Compositions containing quaternary ammonium compounds |
| CN101028240B (zh) | 2007-03-29 | 2010-06-09 | 中国科学院上海药物研究所 | 眼用微乳/亚微乳原位凝胶制剂及其制备方法 |
| US8512687B2 (en) * | 2007-07-09 | 2013-08-20 | Novagali Pharma Sa | Oil in water emulsion comprising NSAIDs and quaternary ammonium halides |
| ES2402321T3 (es) * | 2007-11-05 | 2013-04-30 | Bausch & Lomb Incorporated | Materiales inmiscibles en agua como vehículos para el suministro de fármacos |
| CN101385697B (zh) * | 2008-10-30 | 2012-10-03 | 中国科学院上海药物研究所 | 氟比洛芬酯眼用纳米乳-原位凝胶制剂及其制备方法 |
| DK2437762T3 (da) | 2009-06-05 | 2017-11-20 | Allergan Inc | Kunstige tårer og terapeutiske anvendelser |
| IT1404931B1 (it) * | 2010-06-11 | 2013-12-09 | Medivis S R L | Composizioni oftalmiche per la somministrazione di principi attivi liposolubili . |
| CN102370617B (zh) * | 2010-08-13 | 2013-09-11 | 中国科学院上海药物研究所 | 石杉碱甲眼用微乳制剂及其制备方法 |
| CN103282044B (zh) * | 2010-12-28 | 2016-07-06 | 韩林制药株式会社 | 纳米乳剂形态的眼科用组合物 |
| SI2686017T1 (sl) * | 2011-03-14 | 2019-11-29 | Drug Delivery Solutions Ltd | Očesna sestava |
| JP2013018764A (ja) | 2011-07-14 | 2013-01-31 | Kao Corp | 上皮型ナトリウムチャネル活性化剤 |
| BR112014012463A2 (pt) * | 2011-11-24 | 2017-06-06 | Otsuka Pharma Factory Inc | agente protetor para ceratoconjuntiva ou agente supressor para distúrbio ceratoconjuntival |
| PT2787969T (pt) | 2011-12-07 | 2021-11-09 | Allergan Inc | Entrega eficiente de lípidos para o filme lacrimal humano utilizando um sistema de emulsão sensível ao sal |
| AU2013257830A1 (en) * | 2012-05-11 | 2014-11-20 | Cipla Limited | Pharmaceutical composition |
| JP5084967B1 (ja) * | 2012-06-08 | 2012-11-28 | ライオン株式会社 | 高吸着性ビタミンa含有ナノエマルション粒子を含む眼科用組成物及びその製造方法 |
| HK1214144A1 (zh) | 2012-12-18 | 2016-07-22 | 奥力榨油化株式会社 | 干眼症预防/治疗剂 |
| ES2673009T3 (es) | 2013-03-14 | 2018-06-19 | EyeCRO, LLC | Plataforma de suministro tópico de microemulsiones |
| CN105431138B (zh) * | 2013-03-27 | 2019-01-11 | 全球药物科技有限公司 | 眼药组合物、其制备方法及用途 |
| KR101492447B1 (ko) * | 2013-05-20 | 2015-02-23 | 주식회사태준제약 | 사이클로스포린을 함유하는 나노에멀젼 점안 조성물 및 그의 제조 방법 |
| KR101890503B1 (ko) | 2014-05-01 | 2018-08-21 | 인티그럴 바이오시스템스 엘엘씨 | 안구 장애의 치료를 위한 막-부착성 자가-조립된 시스템 |
| CN105496955A (zh) * | 2015-12-11 | 2016-04-20 | 北京蓝丹医药科技有限公司 | 一种二氟泼尼酯眼用乳剂及其制备方法 |
| CN105663141B (zh) | 2016-03-24 | 2018-06-15 | 北京茗泽中和药物研究有限公司 | 二氟泼尼酯眼用乳剂 |
| CN105726479B (zh) * | 2016-03-24 | 2018-06-22 | 北京茗泽中和药物研究有限公司 | 环孢素眼用乳剂 |
-
2016
- 2016-07-07 DK DK16382321.4T patent/DK3266446T3/en active
- 2016-07-07 SI SI201630160T patent/SI3266446T1/sl unknown
- 2016-07-07 EP EP16382321.4A patent/EP3266446B1/en active Active
- 2016-07-07 PT PT16382321T patent/PT3266446T/pt unknown
- 2016-07-07 ES ES16382321T patent/ES2706535T3/es active Active
- 2016-07-07 RS RS20190077A patent/RS58292B1/sr unknown
- 2016-07-07 PL PL16382321T patent/PL3266446T3/pl unknown
- 2016-07-07 LT LTEP16382321.4T patent/LT3266446T/lt unknown
- 2016-07-07 JO JOP/2017/0147A patent/JOP20170147B1/ar active
-
2017
- 2017-07-06 RU RU2017123797A patent/RU2756758C2/ru active
- 2017-07-06 JP JP2017132403A patent/JP7224095B2/ja active Active
- 2017-07-07 CN CN201710551883.9A patent/CN107582605A/zh active Pending
- 2017-07-07 US US15/644,286 patent/US10660848B2/en active Active
-
2019
- 2019-01-04 HR HRP20190036TT patent/HRP20190036T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20180008538A1 (en) | 2018-01-11 |
| LT3266446T (lt) | 2019-01-25 |
| ES2706535T3 (es) | 2019-03-29 |
| RS58292B1 (sr) | 2019-03-29 |
| DK3266446T3 (en) | 2019-02-11 |
| SI3266446T1 (sl) | 2019-02-28 |
| RU2017123797A (ru) | 2019-01-09 |
| HRP20190036T1 (hr) | 2019-02-22 |
| JP7224095B2 (ja) | 2023-02-17 |
| EP3266446B1 (en) | 2018-11-21 |
| RU2756758C2 (ru) | 2021-10-05 |
| JOP20170147B1 (ar) | 2021-08-17 |
| JOP20170147A1 (ar) | 2019-01-30 |
| EP3266446A1 (en) | 2018-01-10 |
| CN107582605A (zh) | 2018-01-16 |
| US10660848B2 (en) | 2020-05-26 |
| JP2018039781A (ja) | 2018-03-15 |
| RU2017123797A3 (pt) | 2020-09-18 |
| PL3266446T3 (pl) | 2019-05-31 |
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