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PT2739268T - Método e formulação para inalação - Google Patents

Método e formulação para inalação

Info

Publication number
PT2739268T
PT2739268T PT11870462T PT11870462T PT2739268T PT 2739268 T PT2739268 T PT 2739268T PT 11870462 T PT11870462 T PT 11870462T PT 11870462 T PT11870462 T PT 11870462T PT 2739268 T PT2739268 T PT 2739268T
Authority
PT
Portugal
Prior art keywords
formulation
inhalation method
inhalation
Prior art date
Application number
PT11870462T
Other languages
English (en)
Inventor
Mcintosh Michelle
Morton David
Sou Tomas
Olerile Livesey
Prankerd Richard
Original Assignee
Univ Monash
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2011903049A external-priority patent/AU2011903049A0/en
Application filed by Univ Monash filed Critical Univ Monash
Publication of PT2739268T publication Critical patent/PT2739268T/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/095—Oxytocins; Vasopressins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/16—Oxytocins; Vasopressins; Related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Reproductive Health (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
PT11870462T 2011-08-01 2011-11-07 Método e formulação para inalação PT2739268T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AU2011903049A AU2011903049A0 (en) 2011-08-01 Method and formulation for inhalation

Publications (1)

Publication Number Publication Date
PT2739268T true PT2739268T (pt) 2019-01-28

Family

ID=47628537

Family Applications (1)

Application Number Title Priority Date Filing Date
PT11870462T PT2739268T (pt) 2011-08-01 2011-11-07 Método e formulação para inalação

Country Status (21)

Country Link
US (3) US20140294969A1 (pt)
EP (1) EP2739268B1 (pt)
CN (1) CN103841960B (pt)
AU (1) AU2011374218B2 (pt)
BR (1) BR112014002646B1 (pt)
CA (1) CA2879317C (pt)
CY (1) CY1121373T1 (pt)
DK (1) DK2739268T3 (pt)
ES (1) ES2708218T3 (pt)
HR (1) HRP20190080T1 (pt)
HU (1) HUE041858T2 (pt)
LT (1) LT2739268T (pt)
MX (1) MX355833B (pt)
PL (1) PL2739268T3 (pt)
PT (1) PT2739268T (pt)
RS (1) RS58456B1 (pt)
SI (1) SI2739268T1 (pt)
SM (1) SMT201900058T1 (pt)
TR (1) TR201900670T4 (pt)
WO (1) WO2013016754A1 (pt)
ZA (1) ZA201401526B (pt)

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AU2003220125B2 (en) 2002-03-20 2006-06-15 Mannkind Corporation Inhalation apparatus
PL1786784T3 (pl) 2004-08-20 2011-04-29 Mannkind Corp Kataliza syntezy diketopiperazyn
EP2314298B1 (en) 2004-08-23 2015-05-27 MannKind Corporation Microparticles comprising diketopiperazine salts for drug delivery
AU2006290870B2 (en) 2005-09-14 2013-02-28 Mannkind Corporation Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces
DK1986679T3 (da) 2006-02-22 2017-11-20 Mannkind Corp Fremgangsmåde til forbedring af mikropartiklers farmaceutiske egenskaber omfattende diketopiperazin og et aktivt indholdsstof
CN103252007B (zh) 2008-06-13 2016-06-22 曼金德公司 干粉吸入器和用于药物输送的系统
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
JP5479465B2 (ja) 2008-06-20 2014-04-23 マンカインド コーポレイション 吸入努力をリアルタイムにプロファイルする対話式機器および方法
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
RU2531455C2 (ru) 2010-06-21 2014-10-20 Маннкайнд Корпорейшн Системы и способы доставки сухих порошковых лекарств
CN105667994B (zh) 2011-04-01 2018-04-06 曼金德公司 用于药物药盒的泡罩包装
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
DK2739268T3 (en) * 2011-08-01 2019-02-25 Univ Monash PROCEDURE AND FORMULATION FOR INHALATION
WO2013063160A1 (en) 2011-10-24 2013-05-02 Mannkind Corporation Methods and compositions for treating pain
SG11201500218VA (en) 2012-07-12 2015-03-30 Mannkind Corp Dry powder drug delivery systems and methods
US9867931B2 (en) 2013-10-02 2018-01-16 Cook Medical Technologies Llc Therapeutic agents for delivery using a catheter and pressure source
CN105451716A (zh) * 2013-07-18 2016-03-30 曼金德公司 热稳定性干粉药物组合物和方法
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
WO2015175961A1 (en) * 2014-05-16 2015-11-19 Stc.Unm Vaccination compositions, methods of making, and methods of use
CA2965759C (en) * 2014-10-31 2023-12-12 Glaxosmithkline Intellectual Property Development Limited Powdered polypeptides with decreased disulfide impurities comprising divalent cationic materials
WO2017044601A1 (en) * 2015-09-11 2017-03-16 Abbott Laboratories Powdered nutritional product containing branched-chain amino acids and a sugar alcohol
US9585835B1 (en) * 2015-09-16 2017-03-07 Sansa Corporation (Barbados) Inc. Inhalable nicotine formulations and methods of making and using the same
PT108885B (pt) * 2015-10-12 2019-02-13 Hovione Farm S A Método de produção de partículas compósitas inaláveis mediante a utilização de um atomizador de três fluidos
EA201991096A1 (ru) 2016-10-31 2019-09-30 Вектура Лимитед Ингалируемая порошковая композиция, содержащая анти-il-13-антитело
EP3592352A1 (en) * 2017-03-07 2020-01-15 Philip Morris Products S.a.s. Inhalable nicotine formulations, and methods of making and using thereof
CN111202722A (zh) * 2020-02-13 2020-05-29 江苏艾立康药业股份有限公司 一种洛匹那韦吸入干粉药物组合物及其制备方法
CN111202723A (zh) * 2020-02-15 2020-05-29 江苏艾立康药业股份有限公司 一种达芦那韦吸入干粉药物组合物及其制备方法
CN111202724A (zh) * 2020-02-16 2020-05-29 江苏艾立康药业股份有限公司 一种阿比朵尔吸入干粉药物组合物及其制备方法
WO2021247850A2 (en) 2020-06-05 2021-12-09 Cook Medical Technologies Llc Medical scopes for delivering therapeutic agents
CN116419754A (zh) * 2020-08-26 2023-07-11 科威里克斯医疗有限公司 用于治疗和预防肺部感染的葡萄糖苷酶抑制剂

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DK2739268T3 (en) * 2011-08-01 2019-02-25 Univ Monash PROCEDURE AND FORMULATION FOR INHALATION

Also Published As

Publication number Publication date
TR201900670T4 (tr) 2019-02-21
BR112014002646A8 (pt) 2017-06-20
US20220152145A1 (en) 2022-05-19
WO2013016754A1 (en) 2013-02-07
HRP20190080T1 (hr) 2019-03-22
RS58456B1 (sr) 2019-04-30
CA2879317C (en) 2019-01-15
ES2708218T3 (es) 2019-04-09
MX355833B (es) 2018-05-02
AU2011374218A1 (en) 2014-03-20
EP2739268B1 (en) 2018-10-31
HUE041858T2 (hu) 2019-05-28
BR112014002646B1 (pt) 2021-09-14
PL2739268T3 (pl) 2019-07-31
CN103841960B (zh) 2017-07-07
SI2739268T1 (sl) 2019-05-31
CA2879317A1 (en) 2013-02-07
EP2739268A4 (en) 2015-03-25
ZA201401526B (en) 2017-09-27
DK2739268T3 (en) 2019-02-25
EP2739268A1 (en) 2014-06-11
CY1121373T1 (el) 2020-05-29
US20170224762A1 (en) 2017-08-10
AU2011374218B2 (en) 2017-05-11
LT2739268T (lt) 2019-03-25
US12186361B2 (en) 2025-01-07
US20140294969A1 (en) 2014-10-02
MX2014001345A (es) 2014-11-13
US11065297B2 (en) 2021-07-20
CN103841960A (zh) 2014-06-04
BR112014002646A2 (pt) 2017-06-13
SMT201900058T1 (it) 2019-02-28

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