[go: up one dir, main page]

PT2788353T - Ligandos amina com efeito de gaiola para metalo-radiofármacos - Google Patents

Ligandos amina com efeito de gaiola para metalo-radiofármacos

Info

Publication number
PT2788353T
PT2788353T PT128560448T PT12856044T PT2788353T PT 2788353 T PT2788353 T PT 2788353T PT 128560448 T PT128560448 T PT 128560448T PT 12856044 T PT12856044 T PT 12856044T PT 2788353 T PT2788353 T PT 2788353T
Authority
PT
Portugal
Prior art keywords
radiopharmaceuticals
metallo
amine ligands
cage amine
cage
Prior art date
Application number
PT128560448T
Other languages
English (en)
Original Assignee
Clarity Pharmaceuticals Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Clarity Pharmaceuticals Pty Ltd filed Critical Clarity Pharmaceuticals Pty Ltd
Publication of PT2788353T publication Critical patent/PT2788353T/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0474Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0482Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/002Heterocyclic compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08Bridged systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C07F1/08Copper compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05Isotopically modified compounds, e.g. labelled

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Optics & Photonics (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
PT128560448T 2011-12-06 2012-12-06 Ligandos amina com efeito de gaiola para metalo-radiofármacos PT2788353T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161567262P 2011-12-06 2011-12-06

Publications (1)

Publication Number Publication Date
PT2788353T true PT2788353T (pt) 2022-08-12

Family

ID=48573413

Family Applications (1)

Application Number Title Priority Date Filing Date
PT128560448T PT2788353T (pt) 2011-12-06 2012-12-06 Ligandos amina com efeito de gaiola para metalo-radiofármacos

Country Status (8)

Country Link
US (2) US9457107B2 (pt)
EP (2) EP4063369A1 (pt)
JP (1) JP6047581B2 (pt)
AU (1) AU2012350147B2 (pt)
DK (1) DK2788353T3 (pt)
ES (1) ES2924289T3 (pt)
PT (1) PT2788353T (pt)
WO (1) WO2013082656A1 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2012350147B2 (en) 2011-12-06 2017-08-03 Clarity Pharmaceuticals Ltd Cage amine ligands for metallo-radiopharmaceuticals
WO2013181697A1 (en) * 2012-06-05 2013-12-12 The University Of Melbourne Bicyclo[6.1.0]non-4-yne compounds suitable for use as linkers in biological applications
US9597643B1 (en) * 2013-10-22 2017-03-21 U.S. Department Of Energy Surface functionalization of metal organic frameworks for mixed matrix membranes
US9422286B2 (en) * 2014-01-27 2016-08-23 Washington University Metal-binding bifunctional compounds as diagnostic agents for Alzheimer's disease
DK3634965T3 (da) * 2017-06-06 2023-05-01 Clarity Pharmaceuticals Ltd Radiofarmaceutiske lægemidler, radiobilleddannelsesmidler og anvendelser deraf
AU2019251769A1 (en) * 2018-04-11 2020-10-15 Clarity Pharmaceuticals Limited Formulations and kits for radiotherapy and diagnostic imaging
EP3774784A4 (en) 2018-04-11 2021-12-15 Clarity Pharmaceuticals Ltd TARGETING COMPOUNDS AND METHOD FOR CREATING THEREOF
TW202426433A (zh) 2022-09-23 2024-07-01 瑞士商紐利迪姆股份公司 成纖維細胞活化蛋白(fap)抑制劑、fap結合物及其診斷與治療用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0001719A1 (en) 1977-10-26 1979-05-02 The Australian National University Metal complexes, their preparation and production of hydrogen peroxide therewith
WO1995031202A1 (en) 1994-05-17 1995-11-23 Commonwealth Scientific And Industrial Research Organisation Cage compounds, processes for their preparation and their use as antiviral agents
EP1331012A1 (en) 2002-01-29 2003-07-30 BRACCO IMAGING S.p.A. Responsive paramagnetic MRI contrast agents
FI20031528A0 (fi) 2003-10-17 2003-10-17 Ctt Cancer Targeting Tech Oy Terapeuttinen liposomikoostumus ja menetelmä sen valmistamiseksi
WO2010063069A1 (en) * 2008-12-02 2010-06-10 The University Of Melbourne Nitrogen-containing macrocyclic conjugates as radiopharmaceuticals
WO2010121133A2 (en) * 2009-04-17 2010-10-21 The General Hospital Corporation Multimodal imaging of fibrin
AU2012350147B2 (en) 2011-12-06 2017-08-03 Clarity Pharmaceuticals Ltd Cage amine ligands for metallo-radiopharmaceuticals

Also Published As

Publication number Publication date
EP2788353B1 (en) 2022-05-18
US9457107B2 (en) 2016-10-04
US20160354497A1 (en) 2016-12-08
AU2012350147A1 (en) 2014-07-03
JP6047581B2 (ja) 2016-12-21
WO2013082656A1 (en) 2013-06-13
EP4063369A1 (en) 2022-09-28
AU2012350147B2 (en) 2017-08-03
US20140323718A1 (en) 2014-10-30
JP2015500247A (ja) 2015-01-05
DK2788353T3 (da) 2022-08-15
US9861714B2 (en) 2018-01-09
EP2788353A1 (en) 2014-10-15
ES2924289T3 (es) 2022-10-05
EP2788353A4 (en) 2015-04-22

Similar Documents

Publication Publication Date Title
IL233154A0 (en) compounds
GB201107849D0 (en) Cooperative positioning
GB201106395D0 (en) Compounds
GB201109763D0 (en) Compounds
ZA201401553B (en) Cyclopropaneamine compound
ZA201306857B (en) Mesogen-containing compounds
PT2710018T (pt) Compostos macrocíclicos como inibidores de proteína quinases
GB201118652D0 (en) New compounds
GB201118654D0 (en) New compounds
TWI563280B (en) Positioning method
SI2776436T1 (sl) Nove spojine
GB201107197D0 (en) Compounds
GB201122139D0 (en) Compounds
GB201119174D0 (en) Flanged half-bearing
GB201106814D0 (en) New compounds
PT2788353T (pt) Ligandos amina com efeito de gaiola para metalo-radiofármacos
EP2708540A4 (en) PYRIMIDO-DIAZEPINONE COMPOUND
EP2771012A4 (en) NEW CONNECTIONS
GB201110938D0 (en) Compounds
GB201105659D0 (en) Compounds
GB201111415D0 (en) Carrier
GB201118613D0 (en) Compounds
GB201104669D0 (en) Compound
GB2481140B (en) Ball-projecting machine
ZA201401721B (en) Aniline type compounds