PT1991202E - Método para administração de tiotrópio - Google Patents
Método para administração de tiotrópio Download PDFInfo
- Publication number
- PT1991202E PT1991202E PT04801708T PT04801708T PT1991202E PT 1991202 E PT1991202 E PT 1991202E PT 04801708 T PT04801708 T PT 04801708T PT 04801708 T PT04801708 T PT 04801708T PT 1991202 E PT1991202 E PT 1991202E
- Authority
- PT
- Portugal
- Prior art keywords
- dry powder
- dose
- delivered
- inhaler
- administration
- Prior art date
Links
- LERNTVKEWCAPOY-DZZGSBJMSA-N tiotropium Chemical compound O([C@H]1C[C@@H]2[N+]([C@H](C1)[C@@H]1[C@H]2O1)(C)C)C(=O)C(O)(C=1SC=CC=1)C1=CC=CS1 LERNTVKEWCAPOY-DZZGSBJMSA-N 0.000 title 1
- 229940110309 tiotropium Drugs 0.000 title 1
- 239000000843 powder Substances 0.000 abstract 5
- 229940121948 Muscarinic receptor antagonist Drugs 0.000 abstract 1
- 230000004888 barrier function Effects 0.000 abstract 1
- 239000000812 cholinergic antagonist Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940112141 dry powder inhaler Drugs 0.000 abstract 1
- 239000010419 fine particle Substances 0.000 abstract 1
- 210000004072 lung Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Otolaryngology (AREA)
- Hematology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0303270A SE0303270L (sv) | 2003-12-03 | 2003-12-03 | Metod för administration av tiotropium |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1991202E true PT1991202E (pt) | 2009-12-10 |
Family
ID=29778163
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT04801708T PT1991202E (pt) | 2003-12-03 | 2004-12-02 | Método para administração de tiotrópio |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US20050121026A1 (pt) |
| EP (1) | EP1991202B1 (pt) |
| AT (1) | ATE448776T1 (pt) |
| AU (1) | AU2004294887B2 (pt) |
| CA (1) | CA2547660A1 (pt) |
| CY (1) | CY1110625T1 (pt) |
| DE (1) | DE602004024261D1 (pt) |
| DK (1) | DK1991202T3 (pt) |
| ES (1) | ES2333725T3 (pt) |
| PL (1) | PL1991202T3 (pt) |
| PT (1) | PT1991202E (pt) |
| SE (1) | SE0303270L (pt) |
| SI (1) | SI1991202T1 (pt) |
| WO (1) | WO2005053645A1 (pt) |
| ZA (1) | ZA200604254B (pt) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102070630B (zh) * | 2003-11-03 | 2013-04-17 | 贝林格尔.英格海姆国际有限公司 | 结晶噻托碘铵、包含该结晶噻托碘铵的药物制剂及其用途 |
| EP1682543B1 (de) * | 2003-11-03 | 2010-08-18 | Boehringer Ingelheim International Gmbh | Verfahren zur herstellung neuer tiotropiumsalze |
| SE0303269L (sv) * | 2003-12-03 | 2005-06-04 | Microdrug Ag | Medicinsk produkt |
| SE0303570L (sv) * | 2003-12-03 | 2005-06-04 | Microdrug Ag | Fukt-känslig medicinsk produkt |
| SE0303270L (sv) * | 2003-12-03 | 2005-06-04 | Microdrug Ag | Metod för administration av tiotropium |
| CA2547782A1 (en) * | 2003-12-03 | 2005-06-16 | Microdrug Ag | Medical product containing tiotropium |
| SE0303571D0 (sv) * | 2003-12-03 | 2003-12-22 | Microdrug Ag | Medical product for moisture-sensitive medicaments |
| SE0303569L (sv) * | 2003-12-03 | 2005-06-04 | Microdrug Ag | DPI för avlämning av fuktkänsliga medikament |
| TWI274641B (en) * | 2005-08-30 | 2007-03-01 | Rexon Ind Corp Ltd | Cutting machine |
| WO2009079078A1 (en) | 2007-12-14 | 2009-06-25 | Labogroup S.A.S. | Delivering aerosolizable food products |
| ES2739352T3 (es) | 2009-02-26 | 2020-01-30 | Glaxo Group Ltd | Formulaciones farmacéuticas que comprenden 4-{(1R)-2-[(6-{2-[(2,6-diclorobencil)oxi]etoxi}hexil)amino]-1-hidroxietil}-2-(hidroximetil)fenol |
| US8815258B2 (en) | 2009-05-29 | 2014-08-26 | Pearl Therapeutics, Inc. | Compositions, methods and systems for respiratory delivery of two or more active agents |
| TWI792140B (zh) * | 2009-05-29 | 2023-02-11 | 美商沛爾醫療股份有限公司 | 用於經由呼吸道遞送二或更多種活性藥劑的組成物、方法與系統 |
| GB0921075D0 (en) | 2009-12-01 | 2010-01-13 | Glaxo Group Ltd | Novel combination of the therapeutic agents |
| SG11201507286QA (en) | 2013-03-15 | 2015-10-29 | Pearl Therapeutics Inc | Methods and systems for conditioning of particulate crystalline materials |
| AU2014248455B2 (en) | 2013-04-01 | 2018-12-06 | Pulmatrix Operating Company, Inc. | Tiotropium dry powders |
| GB202312252D0 (en) * | 2023-08-10 | 2023-09-27 | Inhalis Therapeutics Sa | Crystalline compositions |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1201114A (en) * | 1980-02-15 | 1986-02-25 | Gordon H. Phillipps | Androstane carbothioates |
| DE3274065D1 (de) * | 1981-07-08 | 1986-12-11 | Draco Ab | Powder inhalator |
| ES286422Y (es) * | 1982-10-08 | 1986-09-16 | Glaxo Group Limited | Dispositivo para administrar medicamentos a pacientes |
| ZW6584A1 (en) * | 1983-04-18 | 1985-04-17 | Glaxo Group Ltd | Phenethanolamine derivatives |
| US5270305A (en) * | 1989-09-08 | 1993-12-14 | Glaxo Group Limited | Medicaments |
| US6536427B2 (en) * | 1990-03-02 | 2003-03-25 | Glaxo Group Limited | Inhalation device |
| GB9004781D0 (en) * | 1990-03-02 | 1990-04-25 | Glaxo Group Ltd | Device |
| US5785049A (en) * | 1994-09-21 | 1998-07-28 | Inhale Therapeutic Systems | Method and apparatus for dispersion of dry powder medicaments |
| US5826633A (en) * | 1996-04-26 | 1998-10-27 | Inhale Therapeutic Systems | Powder filling systems, apparatus and methods |
| US20020017295A1 (en) * | 2000-07-07 | 2002-02-14 | Weers Jeffry G. | Phospholipid-based powders for inhalation |
| DK1131059T3 (da) * | 1998-11-13 | 2003-06-30 | Jago Res Ag | Tørpulver til inhalation |
| ATE294608T1 (de) * | 1999-06-05 | 2005-05-15 | Innovata Biomed Ltd | Verabreichungsystem für medikamente |
| IL149027A0 (en) * | 1999-10-11 | 2002-11-10 | Ml Lab Plc | Medicament delivery device with moisture resistant coating |
| SE517806C2 (sv) * | 1999-11-11 | 2002-07-16 | Microdrug Ag | Doseringsanordning för inhalator |
| SE9904706D0 (sv) * | 1999-12-21 | 1999-12-21 | Astra Ab | An inhalation device |
| PE20011227A1 (es) * | 2000-04-17 | 2002-01-07 | Chiesi Farma Spa | Formulaciones farmaceuticas para inhaladores de polvo seco en la forma de aglomerados duros |
| GB0009468D0 (en) * | 2000-04-17 | 2000-06-07 | Vectura Ltd | Improvements in or relating to formulations for use in inhaler devices |
| GB0015043D0 (en) * | 2000-06-21 | 2000-08-09 | Glaxo Group Ltd | Medicament dispenser |
| SE517225C2 (sv) * | 2000-09-21 | 2002-05-14 | Microdrug Ag | Optimering av en elektrostatiskt doserad inhalator för torrt pulver |
| BR0107304A (pt) * | 2000-10-12 | 2002-08-13 | Boehringer Ingelheim Pharma | Pó para inalação contendo tiotrópio |
| US20030078947A1 (en) * | 2001-10-12 | 2003-04-24 | Intel Corporation | Methods for assigning unique identifiers in a distributed fault tolerant application |
| US7258118B2 (en) * | 2002-01-24 | 2007-08-21 | Sofotec Gmbh & Co, Kg | Pharmaceutical powder cartridge, and inhaler equipped with same |
| US6591832B1 (en) * | 2002-02-21 | 2003-07-15 | Saint-Gobain Calmar Inc. | Dry powder dispenser |
| UA80123C2 (en) * | 2002-04-09 | 2007-08-27 | Boehringer Ingelheim Pharma | Inhalation kit comprising inhalable powder of tiotropium |
| US20030235538A1 (en) * | 2002-04-09 | 2003-12-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Method for the administration of an anticholinergic by inhalation |
| SE524957C2 (sv) * | 2002-04-12 | 2004-11-02 | Microdrug Ag | Förfarande för uppdelning och fördelning i luft av torrt pulvermedikament |
| SE524990C2 (sv) * | 2002-04-12 | 2004-11-09 | Microdrug Ag | Preparation av terapeutiskt torrt pulver samt förfarande för uppdelning och spridning i luft av medicinskt pulver |
| SE525027C2 (sv) * | 2002-04-12 | 2004-11-16 | Microdrug Ag | Anordning utgörande en pulverlufthyvel |
| GB0225621D0 (en) * | 2002-11-02 | 2002-12-11 | Glaxo Group Ltd | Medicament carrier |
| SE0303569L (sv) * | 2003-12-03 | 2005-06-04 | Microdrug Ag | DPI för avlämning av fuktkänsliga medikament |
| SE0303571D0 (sv) * | 2003-12-03 | 2003-12-22 | Microdrug Ag | Medical product for moisture-sensitive medicaments |
| SE0303270L (sv) * | 2003-12-03 | 2005-06-04 | Microdrug Ag | Metod för administration av tiotropium |
| SE0303269L (sv) * | 2003-12-03 | 2005-06-04 | Microdrug Ag | Medicinsk produkt |
| SE0303570L (sv) * | 2003-12-03 | 2005-06-04 | Microdrug Ag | Fukt-känslig medicinsk produkt |
| SE0402345L (sv) * | 2004-09-24 | 2006-03-25 | Mederio Ag | Uppmätt läkemedelsdos |
-
2003
- 2003-12-03 SE SE0303270A patent/SE0303270L/sv unknown
- 2003-12-08 US US10/729,024 patent/US20050121026A1/en not_active Abandoned
-
2004
- 2004-12-02 AU AU2004294887A patent/AU2004294887B2/en not_active Expired
- 2004-12-02 ZA ZA200604254A patent/ZA200604254B/en unknown
- 2004-12-02 CA CA002547660A patent/CA2547660A1/en not_active Abandoned
- 2004-12-02 AT AT04801708T patent/ATE448776T1/de active
- 2004-12-02 ES ES04801708T patent/ES2333725T3/es not_active Expired - Lifetime
- 2004-12-02 DE DE602004024261T patent/DE602004024261D1/de not_active Expired - Lifetime
- 2004-12-02 DK DK04801708.1T patent/DK1991202T3/da active
- 2004-12-02 SI SI200431340T patent/SI1991202T1/sl unknown
- 2004-12-02 PL PL04801708T patent/PL1991202T3/pl unknown
- 2004-12-02 WO PCT/SE2004/001791 patent/WO2005053645A1/en not_active Ceased
- 2004-12-02 PT PT04801708T patent/PT1991202E/pt unknown
- 2004-12-02 EP EP04801708A patent/EP1991202B1/en not_active Expired - Lifetime
-
2006
- 2006-06-08 US US11/448,725 patent/US20070110678A1/en not_active Abandoned
-
2010
- 2010-01-05 CY CY20101100009T patent/CY1110625T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2004294887B2 (en) | 2009-12-24 |
| SE0303270L (sv) | 2005-06-04 |
| DK1991202T3 (da) | 2010-04-06 |
| AU2004294887A1 (en) | 2005-06-16 |
| ES2333725T3 (es) | 2010-02-26 |
| EP1991202A1 (en) | 2008-11-19 |
| WO2005053645A1 (en) | 2005-06-16 |
| CA2547660A1 (en) | 2005-06-16 |
| US20050121026A1 (en) | 2005-06-09 |
| ZA200604254B (en) | 2008-05-28 |
| SE0303270D0 (sv) | 2003-12-03 |
| CY1110625T1 (el) | 2015-04-29 |
| SI1991202T1 (sl) | 2010-03-31 |
| ATE448776T1 (de) | 2009-12-15 |
| US20070110678A1 (en) | 2007-05-17 |
| EP1991202B1 (en) | 2009-11-18 |
| DE602004024261D1 (de) | 2009-12-31 |
| PL1991202T3 (pl) | 2010-05-31 |
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