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CY1110625T1 - Μεθοδος για την χορηγηση τιοτροπιου - Google Patents

Μεθοδος για την χορηγηση τιοτροπιου

Info

Publication number
CY1110625T1
CY1110625T1 CY20101100009T CY101100009T CY1110625T1 CY 1110625 T1 CY1110625 T1 CY 1110625T1 CY 20101100009 T CY20101100009 T CY 20101100009T CY 101100009 T CY101100009 T CY 101100009T CY 1110625 T1 CY1110625 T1 CY 1110625T1
Authority
CY
Cyprus
Prior art keywords
dry powder
dose
delivered
inhaler
administration
Prior art date
Application number
CY20101100009T
Other languages
English (en)
Inventor
Thomas Nilsson
Mattias Myrman
Sven Calander
Alf Niemi
Original Assignee
Boehringer Ingelheim International Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=29778163&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1110625(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim International Gmbh filed Critical Boehringer Ingelheim International Gmbh
Publication of CY1110625T1 publication Critical patent/CY1110625T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Otolaryngology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Αποκαλύπτεται μέθοδος για την χορήγηση και την παρασκευή φαρμακευτικών δόσεων ξηράς σκόνης. Οι δοσομετρημένες δόσεις ξηράς σκόνης διαμορφώνονται από μια λεπτά διαιρεμένη ξηρά σκόνη ενός επιλεγμένου αντιχολινεργικού παράγοντα που χρησιμοποιείται σε μια συσκευή εισπνευστήρα ξηράς σκόνης. Η δοσομετρημένη ιατρική δόση ξηράς σκόνης τακτοποιείται ως ιατρικά αποτελεσματική ποσότητα του επιλεγμένου φαρμάκου επάνω σε μια κλίνη δόσεων και σφραγίζεται στεγανά ως προς την υγρασία με τη χρησιμοποίηση μιας υψηλής σφραγίδας εμποδίου, για την εισαγωγή μέσα σε μια συσκευή εισπνευστήρα εφοδιασμένη με μια συσκευή Air-razor για την απόκτηση κλάσματος λεπτών σωματιδίων, FPF, τουλάχιστον 30 - 50% της παρεχόμενης μάζας σκόνης όταν εφαρμόζεται η αναρρόφηση διαμέσου του εισπνευστήρα, όπου η δόση παρέχεται και εναποτίθεται στον πνεύμονα του χρήστη κατά τη διάρκεια μιας μόνης προσπάθειας εισπνοής.
CY20101100009T 2003-12-03 2010-01-05 Μεθοδος για την χορηγηση τιοτροπιου CY1110625T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0303270A SE0303270L (sv) 2003-12-03 2003-12-03 Metod för administration av tiotropium
EP04801708A EP1991202B1 (en) 2003-12-03 2004-12-02 Method for administration tiotropium

Publications (1)

Publication Number Publication Date
CY1110625T1 true CY1110625T1 (el) 2015-04-29

Family

ID=29778163

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20101100009T CY1110625T1 (el) 2003-12-03 2010-01-05 Μεθοδος για την χορηγηση τιοτροπιου

Country Status (15)

Country Link
US (2) US20050121026A1 (el)
EP (1) EP1991202B1 (el)
AT (1) ATE448776T1 (el)
AU (1) AU2004294887B2 (el)
CA (1) CA2547660A1 (el)
CY (1) CY1110625T1 (el)
DE (1) DE602004024261D1 (el)
DK (1) DK1991202T3 (el)
ES (1) ES2333725T3 (el)
PL (1) PL1991202T3 (el)
PT (1) PT1991202E (el)
SE (1) SE0303270L (el)
SI (1) SI1991202T1 (el)
WO (1) WO2005053645A1 (el)
ZA (1) ZA200604254B (el)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG149876A1 (en) * 2003-11-03 2009-02-27 Boehringer Ingelheim Int Novel tiotropium salts, methods for the production thereof, and pharmaceutical formulations containing the same
UY28590A1 (es) * 2003-11-03 2005-06-30 Boehringer Ingelheim Int Procedimiento para la preparación de nuevas sales de tiotropio, nuevas sales de tiotropio como tales, así como las formulaciones medicamentosas que las contienen.
SE0303269L (sv) * 2003-12-03 2005-06-04 Microdrug Ag Medicinsk produkt
SE0303270L (sv) * 2003-12-03 2005-06-04 Microdrug Ag Metod för administration av tiotropium
WO2005053647A1 (en) * 2003-12-03 2005-06-16 Microdrug Ag Medical product containing tiotropium
SE0303569L (sv) * 2003-12-03 2005-06-04 Microdrug Ag DPI för avlämning av fuktkänsliga medikament
SE0303570L (sv) * 2003-12-03 2005-06-04 Microdrug Ag Fukt-känslig medicinsk produkt
SE0303571D0 (sv) * 2003-12-03 2003-12-22 Microdrug Ag Medical product for moisture-sensitive medicaments
TWI274641B (en) * 2005-08-30 2007-03-01 Rexon Ind Corp Ltd Cutting machine
JP5570996B2 (ja) 2007-12-14 2014-08-13 エアロデザインズ インコーポレイテッド エアロゾル化可能な食料品の送達
EP3578169B1 (en) 2009-02-26 2024-06-26 Glaxo Group Limited Pharmaceutical formulations comprising 4-{(1 r)-2-[(6-{2-[(2,6-dichlorobenzyl)oxy]ethoxy}hexyl)amino]-1-hydroxyethyl}-2-(hydroxymethyl)phenol
US8815258B2 (en) 2009-05-29 2014-08-26 Pearl Therapeutics, Inc. Compositions, methods and systems for respiratory delivery of two or more active agents
EP3106149B1 (en) * 2009-05-29 2019-11-20 Pearl Therapeutics, Inc. Compositions for pulmonary delivery of long-acting muscarinic antagonists and long-acting beta-2 adrenergic receptor agonists and associated methods and systems
GB0921075D0 (en) 2009-12-01 2010-01-13 Glaxo Group Ltd Novel combination of the therapeutic agents
BR112015022784B1 (pt) 2013-03-15 2023-02-14 Pearl Therapeutics, Inc Método de condicionamento de material cristalino micronizado e sistemas de condicionamento
MX2015013845A (es) 2013-04-01 2016-05-09 Pulmatrix Inc Polvos secos de tiotropio.
GB202312252D0 (en) * 2023-08-10 2023-09-27 Inhalis Therapeutics Sa Crystalline compositions

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ES2241611T3 (es) * 1999-06-05 2005-11-01 Innovata Biomed Limited Sisstema de suministro de medicamentos.
CZ20021198A3 (cs) * 1999-10-11 2002-09-11 Ml Laboratories Plc Zařízení pro podávání léčiva s povrchovou úpravou odolnou proti vlhkosti
SE517806C2 (sv) * 1999-11-11 2002-07-16 Microdrug Ag Doseringsanordning för inhalator
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PE20011227A1 (es) * 2000-04-17 2002-01-07 Chiesi Farma Spa Formulaciones farmaceuticas para inhaladores de polvo seco en la forma de aglomerados duros
GB0009468D0 (en) * 2000-04-17 2000-06-07 Vectura Ltd Improvements in or relating to formulations for use in inhaler devices
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SE517225C2 (sv) * 2000-09-21 2002-05-14 Microdrug Ag Optimering av en elektrostatiskt doserad inhalator för torrt pulver
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SE0303269L (sv) * 2003-12-03 2005-06-04 Microdrug Ag Medicinsk produkt
SE0303571D0 (sv) * 2003-12-03 2003-12-22 Microdrug Ag Medical product for moisture-sensitive medicaments
SE0303569L (sv) * 2003-12-03 2005-06-04 Microdrug Ag DPI för avlämning av fuktkänsliga medikament
SE0303270L (sv) * 2003-12-03 2005-06-04 Microdrug Ag Metod för administration av tiotropium
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SE0402345L (sv) * 2004-09-24 2006-03-25 Mederio Ag Uppmätt läkemedelsdos

Also Published As

Publication number Publication date
WO2005053645A1 (en) 2005-06-16
US20050121026A1 (en) 2005-06-09
EP1991202B1 (en) 2009-11-18
AU2004294887B2 (en) 2009-12-24
DK1991202T3 (da) 2010-04-06
SE0303270D0 (sv) 2003-12-03
CA2547660A1 (en) 2005-06-16
AU2004294887A1 (en) 2005-06-16
PL1991202T3 (pl) 2010-05-31
ATE448776T1 (de) 2009-12-15
PT1991202E (pt) 2009-12-10
SE0303270L (sv) 2005-06-04
SI1991202T1 (sl) 2010-03-31
DE602004024261D1 (de) 2009-12-31
ES2333725T3 (es) 2010-02-26
US20070110678A1 (en) 2007-05-17
ZA200604254B (en) 2008-05-28
EP1991202A1 (en) 2008-11-19

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