PT1325001E - Novos anticolinergicos aplicaveis como medicamentos e processo para a sua preparacao - Google Patents

Novos anticolinergicos aplicaveis como medicamentos e processo para a sua preparacao

Info

Publication number: PT1325001E
Authority: PT; Portugal
Prior art keywords: anticolinergic; medicines; applicable; preparation; new
Prior art date: 2000-10-14

Application number

PT01982374T

Other languages

English (en)

Inventor

Rolf Banholzer

Richard Reichl

Georg Speck

Helmut Meissner

Gerd Morschhauser

Michael Paul Pieper

Gerald Pohl

Original Assignee

Boehringer Ingelheim Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-10-14

Filing date

2001-09-28

Publication date

2004-07-30

2001-09-28 Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma

2004-07-30 Publication of PT1325001E publication Critical patent/PT1325001E/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C07D451/06—Oxygen atoms
- C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Pulmonology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Urology & Nephrology (AREA)
Reproductive Health (AREA)
Gynecology & Obstetrics (AREA)
Pregnancy & Childbirth (AREA)
Endocrinology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Hydrogenated Pyridines (AREA)

PT01982374T 2000-10-14 2001-09-28 Novos anticolinergicos aplicaveis como medicamentos e processo para a sua preparacao PT1325001E (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE10050994A DE10050994A1 (de)	2000-10-14	2000-10-14	Neue als Arneimittel einsetzbare Anticholinergika sowie Verfahren zu deren Herstellung

Publications (1)

Publication Number	Publication Date
PT1325001E true PT1325001E (pt)	2004-07-30

Family

ID=7659808

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT01982374T PT1325001E (pt)	2000-10-14	2001-09-28	Novos anticolinergicos aplicaveis como medicamentos e processo para a sua preparacao

Country Status (37)

Country	Link
EP (2)	EP1382606A3 (pt)
JP (2)	JP4109106B2 (pt)
KR (1)	KR100830359B1 (pt)
CN (1)	CN1275962C (pt)
AR (1)	AR035589A1 (pt)
AT (1)	ATE259805T1 (pt)
AU (2)	AU2002213975B2 (pt)
BG (1)	BG66225B1 (pt)
BR (1)	BR0114635A (pt)
CA (1)	CA2425557C (pt)
DE (2)	DE10050994A1 (pt)
DK (1)	DK1325001T3 (pt)
EA (1)	EA005816B1 (pt)
EC (1)	ECSP034542A (pt)
EE (1)	EE05179B1 (pt)
ES (1)	ES2215147T3 (pt)
HR (1)	HRP20030278B1 (pt)
HU (1)	HUP0301203A3 (pt)
IL (2)	IL155334A0 (pt)
ME (1)	MEP39908A (pt)
MX (1)	MXPA03003160A (pt)
MY (1)	MY127144A (pt)
NO (1)	NO328207B1 (pt)
NZ (1)	NZ525836A (pt)
PE (1)	PE20020433A1 (pt)
PL (1)	PL207311B1 (pt)
PT (1)	PT1325001E (pt)
RS (1)	RS50464B (pt)
SA (1)	SA01220414B1 (pt)
SI (1)	SI1325001T1 (pt)
SK (1)	SK287138B6 (pt)
TR (1)	TR200400376T4 (pt)
TW (1)	TWI306098B (pt)
UA (1)	UA73804C2 (pt)
UY (1)	UY26958A1 (pt)
WO (1)	WO2002032899A1 (pt)
ZA (1)	ZA200302914B (pt)

Families Citing this family (80)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE10200943A1 (de) *	2002-01-12	2003-07-24	Boehringer Ingelheim Pharma	Verfahren zur Herstellung von Scopinestern
US7405224B2 (en)	2002-01-31	2008-07-29	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Xanthenecarboxylates, processes for preparing them, and their use as pharmaceutical compositions
DE10203753A1 (de) *	2002-01-31	2003-08-14	Boehringer Ingelheim Pharma	Neue Xanthencarbonsäureester, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel
US7084153B2 (en)	2002-04-12	2006-08-01	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Medicaments comprising steroids and a novel anticholinergic
US7417051B2 (en)	2002-04-12	2008-08-26	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Medicaments comprising betamimetics and a novel anticholinergic
DE10216429A1 (de) *	2002-04-12	2003-10-23	Boehringer Ingelheim Pharma	Arzneimittel enthaltend Steroide und ein neues Anticholinergikum
PL213489B1 (pl) *	2002-04-12	2013-03-29	Boehringer Ingelheim Pharma	Kompozycje farmaceutyczne zawierajace betamimetyk i nowy lek antycholinergiczny oraz zastosowanie kompozycji
DE10256317A1 (de) *	2002-04-12	2003-10-23	Boehringer Ingelheim Pharma	Arzneimittel enthaltend Betamimetika und ein neues Anticholinergikum
DE10224091A1 (de) *	2002-05-31	2003-12-11	Boehringer Ingelheim Pharma	Technisches Verfahren zur Herstellung von Tropenol
DE10230769A1 (de) *	2002-07-09	2004-01-22	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Neue Arzneimittelkompositionen auf der Basis neuer Anticholinergika und PDE-IV-Inhibitoren
JP2005538066A (ja) *	2002-07-09	2005-12-15	ベーリンガーインゲルハイムファルマゲゼルシャフトミットベシュレンクテルハフツングウントコンパニーコマンディトゲゼルシャフト	新規な抗コリン作用薬及びｐ３８キナーゼ阻害剤を用いた新規な医薬組成物
DE10230751A1 (de) *	2002-07-09	2004-01-22	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Neue Arzneimittelkompositionen auf der Basis neuer Anticholinergika und EGFR-Kinase-Hemmern
DE10230750A1 (de) *	2002-07-09	2004-01-22	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Neue Arzneimittelkompositionen auf der Basis neuer Anticholonergika und NK1-Rezeptor-Antagonisten
EP1908468A1 (de) *	2002-08-14	2008-04-09	Boehringer Ingelheim Pharma GmbH & Co. KG	Aerosolformulierung für die Inhalation enthaltend ein Anticholinergikum
US7244742B2 (en)	2002-08-17	2007-07-17	Boehringer Ingelheim Pharma Gmbh & Co Kg	Pharmaceutical compositions for inhalation containing an anticholinergic, corticosteroid and betamimetic
DE10237739A1 (de) *	2002-08-17	2004-02-26	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Inhalative Arzneimittel enthaltend ein neues Anticholinergikum in Kombination mit Corticosteroiden und Betamimetika
US7056916B2 (en)	2002-11-15	2006-06-06	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Medicaments for the treatment of chronic obstructive pulmonary disease
DE10317461A1 (de)	2003-04-16	2004-10-28	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Radioaktiv markierte Mikropartikel, Verfahren zu deren Herstellung und deren Verwendung
US7332175B2 (en)	2003-05-27	2008-02-19	Boehringer Ingelheim International Gmbh	Long-acting drug combinations for the treatment of respiratory complaints
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US7462367B2 (en)	2003-07-11	2008-12-09	Boehringer Ingelheim International Gmbh	Anticholinergic powder formulations for inhalation
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US7273603B2 (en) *	2003-07-11	2007-09-25	Boehringer Ingelheim International Gmbh	HFC solution formulations containing an anticholinergic
DE602004021815D1 (de) *	2003-07-28	2009-08-13	Boehringer Ingelheim Pharma	Medikamente zur inhalation mit steroiden und einem neuen fluorencarbonsäureester
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EP1651208A1 (en) *	2003-07-28	2006-05-03	Boehringer Ingelheim International GmbH	Medicaments comprising pde iv inhibitors and a novel anticholinergic and their use for treating respiratory disorders
JP2007500151A (ja) *	2003-07-29	2007-01-11	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	ベータ受容体刺激薬及び抗コリン薬を含む吸入用医薬
JP2007500676A (ja) *	2003-07-31	2007-01-18	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	抗コリン作用薬とベータ受容体刺激薬を含む吸入用薬剤
EP1504756A1 (en) *	2003-08-06	2005-02-09	Kyowa Hakko Kogyo Co., Ltd	Medicament compositions comprising a heterocyclic compound and an anticholinergic
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WO2005067929A1 (en) *	2004-01-09	2005-07-28	Boehringer Ingelheim International Gmbh	New pharmaceutical compositions based on a scopineester and nicotinamide derivatives
JP2007523116A (ja) *	2004-02-20	2007-08-16	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	抗コリン作用薬及びｐｅｇｓｕｎｅｒｃｅｐｔを基にした新規な医薬組成物
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US7220742B2 (en)	2004-05-14	2007-05-22	Boehringer Ingelheim International Gmbh	Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments
DE602004020337D1 (de) *	2004-08-11	2009-05-14	Boehringer Ingelheim Pharma	Anticholinergika enthaltende Arzneimittel zur Behandlung von Krankheiten der ableitenden Harnwege
DE102004056578A1 (de) *	2004-11-23	2006-05-24	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Inhalative Arzneimittel enthaltend ein neues Anticholinergikum, Formoterol und ein Steroid
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WO2006094924A2 (en) *	2005-03-09	2006-09-14	Boehringer Ingelheim International Gmbh	New pharmaceutical compositions based on anticholinergics and pde 5-inhibitors
WO2006128847A2 (en) *	2005-05-31	2006-12-07	Boehringer Ingelheim International Gmbh	Medicament containing a betamimetic in conjunction with an anticholinergic and a pde iv inhibitor
EP1898894A1 (en) *	2005-06-17	2008-03-19	Boehringer Ingelheim International GmbH	Mrp iv inhibitors for the treatment of respiratory diseases
DE102005030733A1 (de)	2005-07-01	2007-01-04	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Neue Arzneimittelkombinationen zur Behandlung von Atemwegserkrankungen enthaltend langwirksame Beta-2-Agonisten und wenigstens einen weiteren Wirkstoff
WO2007020227A1 (de)	2005-08-15	2007-02-22	Boehringer Ingelheim International Gmbh	Verfahren zur herstellung von betamimetika
US20090221664A1 (en)	2005-10-19	2009-09-03	Abhijit Ray	Pharmaceutical compositions of muscarinic receptor antagonists
DE102005055961A1 (de) *	2005-11-24	2007-05-31	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Aerosolformulierung für die Inhalation enthaltend ein Anticholinergikum
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DE102005055963A1 (de) *	2005-11-24	2007-07-19	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Aerosolformulierung für die Inhalation enthaltend ein Anticholinergikum
WO2008017637A1 (de)	2006-08-07	2008-02-14	Boehringer Ingelheim International Gmbh	Arzneimittelkombinationen zur behandlung von atemwegserkrankungen
EP1958947A1 (en)	2007-02-15	2008-08-20	Ranbaxy Laboratories Limited	Inhibitors of phosphodiesterase type 4
ATE545417T1 (de)	2007-03-14	2012-03-15	Ranbaxy Lab Ltd	Pyrazoloä3,4-büpyridin-derivate als phosphodiesterasehemmer
EP2011538B1 (en)	2007-07-06	2016-02-17	Vectura Delivery Devices Limited	Inhaler
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EP2082771A1 (en)	2008-01-24	2009-07-29	Vectura Delivery Devices Limited	Inhaler
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EP2082772A1 (en)	2008-01-24	2009-07-29	Vectura Delivery Devices Limited	Inhaler
EP2082767A1 (en)	2008-01-24	2009-07-29	Vectura Delivery Devices Limited	Inhaler
EP2111861A1 (en)	2008-04-21	2009-10-28	Ranbaxy Laboratories Limited	Compositions of phosphodiesterase type IV inhibitors
US10011906B2 (en)	2009-03-31	2018-07-03	Beohringer Ingelheim International Gmbh	Method for coating a surface of a component
EP3508239B1 (de)	2009-05-18	2020-12-23	Boehringer Ingelheim International GmbH	Adapter, inhalationseinrichtung und zerstäuber
GB0918450D0 (en)	2009-10-21	2009-12-09	Innovata Ltd	Composition
EA026241B1 (ru)	2009-11-25	2017-03-31	Бёрингер Ингельхайм Интернациональ Гмбх	Распылитель
US10016568B2 (en)	2009-11-25	2018-07-10	Boehringer Ingelheim International Gmbh	Nebulizer
JP5658268B2 (ja)	2009-11-25	2015-01-21	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	ネブライザ
JP5874724B2 (ja)	2010-06-24	2016-03-02	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	ネブライザ
EP2694220B1 (de)	2011-04-01	2020-05-06	Boehringer Ingelheim International GmbH	Medizinisches gerät mit behälter
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WO2015169732A1 (en)	2014-05-07	2015-11-12	Boehringer Ingelheim International Gmbh	Container, nebulizer and use
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ES2759247T3 (es) *	2014-06-18	2020-05-08	Boehringer Ingelheim Vetmedica Gmbh	Antagonistas muscarínicos y combinaciones de estos para el tratamiento de enfermedades de las vías respiratorias en caballos
US9994572B2 (en) *	2015-09-04	2018-06-12	Janssen Pharmaceutica Nv	Therapeutic compounds for pain and synthesis thereof
CN113292574B (zh) *	2020-02-21	2022-05-03	四川大学	一类手性多环的托品烷化合物及其制备方法和用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4003270A1 (de) *	1990-02-03	1991-08-08	Boehringer Ingelheim Kg	Neue treibgase und ihre verwendung in arzneimittelzubereitungen
DE4108393A1 (de) *	1991-03-15	1992-09-17	Boehringer Ingelheim Kg	Neue ester bi- und tricyclischer aminoalkohole, ihre herstellung und ihre verwendung in arzneimitteln

2000
- 2000-10-14 DE DE10050994A patent/DE10050994A1/de not_active Withdrawn
2001
- 2001-09-28 SI SI200130085T patent/SI1325001T1/xx unknown
- 2001-09-28 IL IL15533401A patent/IL155334A0/xx active IP Right Grant
- 2001-09-28 UA UA2003054186A patent/UA73804C2/uk unknown
- 2001-09-28 PT PT01982374T patent/PT1325001E/pt unknown
- 2001-09-28 JP JP2002536281A patent/JP4109106B2/ja not_active Expired - Lifetime
- 2001-09-28 ME MEP-399/08A patent/MEP39908A/xx unknown
- 2001-09-28 NZ NZ525836A patent/NZ525836A/en not_active IP Right Cessation
- 2001-09-28 SK SK435-2003A patent/SK287138B6/sk not_active IP Right Cessation
- 2001-09-28 CN CNB018171443A patent/CN1275962C/zh not_active Expired - Lifetime
- 2001-09-28 PL PL360673A patent/PL207311B1/pl not_active IP Right Cessation
- 2001-09-28 CA CA002425557A patent/CA2425557C/en not_active Expired - Lifetime
- 2001-09-28 MX MXPA03003160A patent/MXPA03003160A/es active IP Right Grant
- 2001-09-28 AT AT01982374T patent/ATE259805T1/de active
- 2001-09-28 WO PCT/EP2001/011226 patent/WO2002032899A1/de not_active Ceased
- 2001-09-28 EA EA200300459A patent/EA005816B1/ru not_active IP Right Cessation
- 2001-09-28 TR TR2004/00376T patent/TR200400376T4/xx unknown
- 2001-09-28 EP EP03023933A patent/EP1382606A3/de not_active Withdrawn
- 2001-09-28 ES ES01982374T patent/ES2215147T3/es not_active Expired - Lifetime
- 2001-09-28 EP EP01982374A patent/EP1325001B1/de not_active Expired - Lifetime
- 2001-09-28 AU AU2002213975A patent/AU2002213975B2/en not_active Expired
- 2001-09-28 EE EEP200300151A patent/EE05179B1/xx not_active IP Right Cessation
- 2001-09-28 DE DE50101524T patent/DE50101524D1/de not_active Expired - Lifetime
- 2001-09-28 KR KR1020037005256A patent/KR100830359B1/ko not_active Expired - Fee Related
- 2001-09-28 RS YUP-295/03A patent/RS50464B/sr unknown
- 2001-09-28 HU HU0301203A patent/HUP0301203A3/hu unknown
- 2001-09-28 AU AU1397502A patent/AU1397502A/xx active Pending
- 2001-09-28 DK DK01982374T patent/DK1325001T3/da active
- 2001-09-28 BR BR0114635-1A patent/BR0114635A/pt not_active IP Right Cessation
- 2001-09-28 HR HR20030278A patent/HRP20030278B1/xx not_active IP Right Cessation
- 2001-10-02 SA SA01220414A patent/SA01220414B1/ar unknown
- 2001-10-10 UY UY26958A patent/UY26958A1/es not_active Application Discontinuation
- 2001-10-12 PE PE2001001018A patent/PE20020433A1/es not_active Application Discontinuation
- 2001-10-12 AR ARP010104785A patent/AR035589A1/es active IP Right Grant
- 2001-10-12 MY MYPI20014765A patent/MY127144A/en unknown
- 2001-10-12 TW TW090125220A patent/TWI306098B/zh not_active IP Right Cessation
2003
- 2003-03-28 BG BG107688A patent/BG66225B1/bg unknown
- 2003-04-07 EC EC2003004542A patent/ECSP034542A/es unknown
- 2003-04-10 IL IL155334A patent/IL155334A/en not_active IP Right Cessation
- 2003-04-11 ZA ZA200302914A patent/ZA200302914B/en unknown
- 2003-04-11 NO NO20031693A patent/NO328207B1/no not_active IP Right Cessation
2008
- 2008-02-14 JP JP2008033492A patent/JP2008120834A/ja active Pending

Also Published As

Publication number	Publication date
NO20031693L (no)	2003-05-28
YU29503A (sh)	2006-03-03
ZA200302914B (en)	2003-11-14
BG66225B1 (bg)	2012-06-29
IL155334A (en)	2009-02-11
ECSP034542A (es)	2003-06-25
CN1468236A (zh)	2004-01-14
MXPA03003160A (es)	2005-09-09
WO2002032899A1 (de)	2002-04-25
HUP0301203A3 (en)	2006-05-29
JP2008120834A (ja)	2008-05-29
SK287138B6 (sk)	2010-01-07
IL155334A0 (en)	2003-11-23
DK1325001T3 (da)	2004-06-21
EP1382606A2 (de)	2004-01-21
EP1325001B1 (de)	2004-02-18
ATE259805T1 (de)	2004-03-15
PL360673A1 (en)	2004-09-20
CA2425557A1 (en)	2003-04-11
UY26958A1 (es)	2002-06-20
NZ525836A (en)	2004-09-24
PE20020433A1 (es)	2002-06-28
BG107688A (bg)	2003-09-30
JP2004511557A (ja)	2004-04-15
JP4109106B2 (ja)	2008-07-02
TR200400376T4 (tr)	2004-03-22
HRP20030278B1 (en)	2006-02-28
TWI306098B (en)	2009-02-11
EP1382606A3 (de)	2004-10-13
PL207311B1 (pl)	2010-11-30
MEP39908A (en)	2011-02-10
SI1325001T1 (sl)	2004-08-31
EE200300151A (et)	2003-06-16
NO328207B1 (no)	2010-01-11
EP1325001A1 (de)	2003-07-09
AU1397502A (en)	2002-04-29
HUP0301203A2 (hu)	2003-10-28
NO20031693D0 (no)	2003-04-11
BR0114635A (pt)	2004-02-10
KR100830359B1 (ko)	2008-05-20
KR20030041165A (ko)	2003-05-23
AU2002213975B2 (en)	2006-11-09
CN1275962C (zh)	2006-09-20
HK1060566A1 (en)	2004-08-13
SA01220414B1 (ar)	2007-01-20
MY127144A (en)	2006-11-30
UA73804C2 (en)	2005-09-15
DE10050994A1 (de)	2002-04-18
EA200300459A1 (ru)	2003-10-30
AR035589A1 (es)	2004-06-16
EA005816B1 (ru)	2005-06-30
CA2425557C (en)	2007-11-13
RS50464B (sr)	2010-03-02
EE05179B1 (et)	2009-06-15
ES2215147T3 (es)	2004-10-01
DE50101524D1 (de)	2004-03-25
SK4352003A3 (en)	2003-08-05
HRP20030278A2 (en)	2005-02-28

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