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PT1105391E - Compostos de imidazo [1,2-a] piridinas que inibem a secrecao acida gastrica, composicoes farmaceuticas destes e processos para a sua preparacao - Google Patents

Compostos de imidazo [1,2-a] piridinas que inibem a secrecao acida gastrica, composicoes farmaceuticas destes e processos para a sua preparacao

Info

Publication number
PT1105391E
PT1105391E PT99944966T PT99944966T PT1105391E PT 1105391 E PT1105391 E PT 1105391E PT 99944966 T PT99944966 T PT 99944966T PT 99944966 T PT99944966 T PT 99944966T PT 1105391 E PT1105391 E PT 1105391E
Authority
PT
Portugal
Prior art keywords
secrecy
pyridines
processes
preparation
pharmaceutical compositions
Prior art date
Application number
PT99944966T
Other languages
English (en)
Portuguese (pt)
Inventor
Kosrat Amin
Peter Nordberg
Ingemar Starke
Dahlstroem Mikael
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of PT1105391E publication Critical patent/PT1105391E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
PT99944966T 1998-08-21 1999-08-18 Compostos de imidazo [1,2-a] piridinas que inibem a secrecao acida gastrica, composicoes farmaceuticas destes e processos para a sua preparacao PT1105391E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9802794A SE9802794D0 (sv) 1998-08-21 1998-08-21 New compounds

Publications (1)

Publication Number Publication Date
PT1105391E true PT1105391E (pt) 2005-01-31

Family

ID=20412307

Family Applications (1)

Application Number Title Priority Date Filing Date
PT99944966T PT1105391E (pt) 1998-08-21 1999-08-18 Compostos de imidazo [1,2-a] piridinas que inibem a secrecao acida gastrica, composicoes farmaceuticas destes e processos para a sua preparacao

Country Status (20)

Country Link
US (3) US6579884B1 (fr)
EP (2) EP1105391B1 (fr)
JP (1) JP2002523415A (fr)
KR (1) KR20010072798A (fr)
CN (1) CN1329613A (fr)
AR (1) AR020226A1 (fr)
AT (1) ATE280768T1 (fr)
AU (1) AU5767999A (fr)
BR (1) BR9913103A (fr)
CA (1) CA2339286A1 (fr)
DE (1) DE69921483T2 (fr)
DK (1) DK1105391T3 (fr)
ES (1) ES2229763T3 (fr)
IL (1) IL141166A0 (fr)
NO (1) NO20010860L (fr)
PT (1) PT1105391E (fr)
SE (1) SE9802794D0 (fr)
SI (1) SI1105391T1 (fr)
WO (1) WO2000011000A2 (fr)
ZA (1) ZA200100913B (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9802794D0 (sv) * 1998-08-21 1998-08-21 Astra Ab New compounds
SE0003186D0 (sv) * 2000-09-07 2000-09-07 Astrazeneca Ab New process
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
SE0102808D0 (sv) * 2001-08-22 2001-08-22 Astrazeneca Ab New compounds
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
AU2003270846B2 (en) * 2002-09-19 2006-11-23 Merck Sharp & Dohme Corp. Pyrazolopyridines as cyclin dependent kinase inhibitors
JP4845379B2 (ja) * 2002-09-19 2011-12-28 シェーリング コーポレイション サイクリン依存性キナーゼインヒビターとしてのイミダゾピリジン
DE602004023921D1 (de) 2003-03-10 2009-12-17 Nycomed Gmbh Neues verfahren zur herstellung vonroflumilast
SE0301904D0 (sv) 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound II with therapeutic effect
US8536492B2 (en) * 2003-10-27 2013-09-17 Applied Materials, Inc. Processing multilayer semiconductors with multiple heat sources
US20080280944A1 (en) 2003-11-03 2008-11-13 Paula Fernstrom Imidazo[1,2-A]Pyridine Derivatives For The Treatment Of Silent Gastro-Esophageal Reflux
US20080033006A1 (en) * 2004-01-26 2008-02-07 Altana Pharma Ag 1,2,4-Triazolo[ 1,5-A] Pyridines as Gastric Acid Secretion Inhibitors
KR20220084426A (ko) * 2004-07-28 2022-06-21 다케다 야쿠힌 고교 가부시키가이샤 피롤로〔2,3-ｃ〕피리딘 화합물, 그 제조 방법 및 용도
US8663694B2 (en) * 2005-03-16 2014-03-04 Takeda Gmbh Taste masked dosage form containing roflumilast
EP2099798A1 (fr) * 2006-12-01 2009-09-16 Galapagos N.V. Composés d'imidazolopyridine pour le traitement des maladies dégénératives et inflammatoires
WO2009042907A1 (fr) * 2007-09-27 2009-04-02 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Composés d'isoindoline pour le traitement d'une amyotrophie spinale et autres utilisations
CN102470126A (zh) 2009-07-09 2012-05-23 拉夸里亚创药株式会社 用于治疗与异常肠胃运动有关的疾病的酸泵拮抗剂
CN111606846A (zh) * 2020-05-12 2020-09-01 广州理文科技有限公司 一种n`-三氟甲磺酰基n杂芳香胺类化合物及其制备方法
WO2025058459A1 (fr) * 2023-09-15 2025-03-20 (주)휴온스 Nouveau composé à base d'imidazopyridine et composition le comprenant en tant que principe actif pour prévenir, soulager ou traiter des maladies inflammatoires gastro-intestinales ou des maladies associées à l'acide gastrique

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA81219B (en) * 1980-01-23 1982-01-27 Schering Corp Imidazo (1,2-a) pyridines ,process for their preparation and pharmaceutical compositions containing them
EP0068378B1 (fr) * 1981-06-26 1986-03-05 Schering Corporation Imidazo(1,2-a)pyridines et pyrazines, procédés pour leur préparation et composés pharmaceutiques les contenant
US4725601A (en) 1985-06-04 1988-02-16 Fujisawa Pharmaceutical Co., Ltd. Certain imidazo[1,2-a]pyridines useful in the treatment of ulcers
US5574042A (en) * 1992-11-02 1996-11-12 Fujisawa Pharmaceutical Co., Ltd Imidazo [1,2-a] pyridines and their pharmaceutical use
IL108520A (en) 1993-02-15 1997-09-30 Byk Gulden Lomberg Chem Fab 2, 3, 8-TRISUBSTITUTED IMIDAZO £1, 2-a| PYRIDINE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
DE59409983D1 (de) * 1993-04-22 2002-01-10 Byk Gulden Lomberg Chem Fab Pyridiniumsalze und ihre verwendung zur bekämpfung von helicobacter-bakterien
UA48122C2 (uk) * 1993-10-11 2002-08-15 Бік Гульден Ломберг Хеміше Фабрік Гмбх АЛКОКСІАЛКІЛКАРБАМАТИ ІМІДАЗО[1,2-а]ПІРИДИНІВ, СПОСІБ ЇХ ОДЕРЖАННЯ ТА ЛІКАРСЬКИЙ ЗАСІБ НА ЇХ ОСНОВІ
MX9700624A (es) 1994-07-28 1997-12-31 Byk Gulden Lomberg Chem Fab Azolidinonas de imidazopiridina.
EP0773944A1 (fr) * 1994-07-28 1997-05-21 Byk Gulden Lomberg Chemische Fabrik GmbH Benzylimidazopyridines
CA2196075A1 (fr) 1994-07-28 1996-02-08 Gerhard Grundler Imidazopyridines halogenees
EP0773945A1 (fr) 1994-07-28 1997-05-21 Byk Gulden Lomberg Chemische Fabrik GmbH Acylimidazopyridines
DE19602853A1 (de) * 1996-01-26 1997-07-31 Byk Gulden Lomberg Chem Fab Neue Halogenimidazopyridine
US6096758A (en) 1996-01-26 2000-08-01 Byk Gulden Lomberg Chemische Fabrik Gmbh 3-methylimidazopyridines
SE9700661D0 (sv) * 1997-02-25 1997-02-25 Astra Ab New compounds
SE9801526D0 (sv) * 1998-04-29 1998-04-29 Astra Ab New compounds
SE9802793D0 (sv) * 1998-08-21 1998-08-21 Astra Ab New compounds
SE9802794D0 (sv) * 1998-08-21 1998-08-21 Astra Ab New compounds

Also Published As

Publication number Publication date
US20050154007A1 (en) 2005-07-14
NO20010860D0 (no) 2001-02-20
WO2000011000A3 (fr) 2000-06-15
CN1329613A (zh) 2002-01-02
US6790960B2 (en) 2004-09-14
NO20010860L (no) 2001-04-23
EP1105391A2 (fr) 2001-06-13
SE9802794D0 (sv) 1998-08-21
US6579884B1 (en) 2003-06-17
SI1105391T1 (en) 2005-02-28
US20030220364A1 (en) 2003-11-27
BR9913103A (pt) 2001-05-08
DE69921483D1 (de) 2004-12-02
EP1411056A2 (fr) 2004-04-21
EP1411056A3 (fr) 2004-04-28
IL141166A0 (en) 2002-02-10
AU5767999A (en) 2000-03-14
CA2339286A1 (fr) 2000-03-02
AR020226A1 (es) 2002-05-02
DE69921483T2 (de) 2006-02-02
ES2229763T3 (es) 2005-04-16
ZA200100913B (en) 2002-05-02
JP2002523415A (ja) 2002-07-30
KR20010072798A (ko) 2001-07-31
DK1105391T3 (da) 2005-01-24
ATE280768T1 (de) 2004-11-15
WO2000011000A2 (fr) 2000-03-02
EP1105391B1 (fr) 2004-10-27

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