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DK1105391T3 - Imidazo[1,2-a]pyridin-forbindelser som inhiberer mavesyreudskillelse, farmaceutiske præparater deraf og fremgangsmåder til deres fremstilling - Google Patents

Imidazo[1,2-a]pyridin-forbindelser som inhiberer mavesyreudskillelse, farmaceutiske præparater deraf og fremgangsmåder til deres fremstilling

Info

Publication number
DK1105391T3
DK1105391T3 DK99944966T DK99944966T DK1105391T3 DK 1105391 T3 DK1105391 T3 DK 1105391T3 DK 99944966 T DK99944966 T DK 99944966T DK 99944966 T DK99944966 T DK 99944966T DK 1105391 T3 DK1105391 T3 DK 1105391T3
Authority
DK
Denmark
Prior art keywords
imidazo
preparation
methods
pharmaceutical compositions
gastric acid
Prior art date
Application number
DK99944966T
Other languages
English (en)
Inventor
Kosrat Amin
Mikael Dahlstroem
Peter Nordberg
Ingemar Starke
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of DK1105391T3 publication Critical patent/DK1105391T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK99944966T 1998-08-21 1999-08-18 Imidazo[1,2-a]pyridin-forbindelser som inhiberer mavesyreudskillelse, farmaceutiske præparater deraf og fremgangsmåder til deres fremstilling DK1105391T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9802794A SE9802794D0 (sv) 1998-08-21 1998-08-21 New compounds
PCT/SE1999/001402 WO2000011000A2 (en) 1998-08-21 1999-08-18 New compounds

Publications (1)

Publication Number Publication Date
DK1105391T3 true DK1105391T3 (da) 2005-01-24

Family

ID=20412307

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99944966T DK1105391T3 (da) 1998-08-21 1999-08-18 Imidazo[1,2-a]pyridin-forbindelser som inhiberer mavesyreudskillelse, farmaceutiske præparater deraf og fremgangsmåder til deres fremstilling

Country Status (20)

Country Link
US (3) US6579884B1 (da)
EP (2) EP1411056A3 (da)
JP (1) JP2002523415A (da)
KR (1) KR20010072798A (da)
CN (1) CN1329613A (da)
AR (1) AR020226A1 (da)
AT (1) ATE280768T1 (da)
AU (1) AU5767999A (da)
BR (1) BR9913103A (da)
CA (1) CA2339286A1 (da)
DE (1) DE69921483T2 (da)
DK (1) DK1105391T3 (da)
ES (1) ES2229763T3 (da)
IL (1) IL141166A0 (da)
NO (1) NO20010860L (da)
PT (1) PT1105391E (da)
SE (1) SE9802794D0 (da)
SI (1) SI1105391T1 (da)
WO (1) WO2000011000A2 (da)
ZA (1) ZA200100913B (da)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9802794D0 (sv) * 1998-08-21 1998-08-21 Astra Ab New compounds
SE0003186D0 (sv) * 2000-09-07 2000-09-07 Astrazeneca Ab New process
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
SE0102808D0 (sv) * 2001-08-22 2001-08-22 Astrazeneca Ab New compounds
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
CA2499593C (en) * 2002-09-19 2011-08-16 Michael P. Dwyer Pyrazolopyridines as cyclin dependent kinase inhibitors
CA2499639C (en) * 2002-09-19 2011-11-08 Schering Corporation Imidazopyridines as cyclin dependent kinase inhibitors
ES2335498T3 (es) 2003-03-10 2010-03-29 Nycomed Gmbh Nuevo proceso para la preparacion de reflumilast.
SE0301904D0 (sv) 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound II with therapeutic effect
US8536492B2 (en) * 2003-10-27 2013-09-17 Applied Materials, Inc. Processing multilayer semiconductors with multiple heat sources
CA2544325A1 (en) 2003-11-03 2005-05-12 Astrazeneca Ab Imidazo [1,2-a] pyridine derivatives for the treatment of silent gastro-esophageal reflux
EP1711498A2 (en) * 2004-01-26 2006-10-18 Altana Pharma AG 1,2,4-triazolo¬1,5-a|pyridines as gastric acid secretion inhibitors
ATE527258T1 (de) * 2004-07-28 2011-10-15 Takeda Pharmaceutical Pyrroloä2,3-cüpyridinverbindung, verfahren zu deren herstellung und anwendung
EP2258350B1 (en) * 2005-03-16 2014-12-24 Takeda GmbH Taste masked dosage form containing roflumilast
EP2099798A1 (en) * 2006-12-01 2009-09-16 Galapagos N.V. Imidazolopyridine compounds useful for the treatment of degenerative and inflammatory diseases
CA2700841A1 (en) * 2007-09-27 2009-04-02 The United States Of America, As Represented By The Secretary, Departmen T Of Health And Human Services Isoindoline compounds for the treatment of spinal muscular atrophy and other uses
MX2012000275A (es) 2009-07-09 2012-02-08 Raqualia Pharma Inc Antagonista de bomba de acido para el tratamiento de enfermedades involucradas en la motilidad gastrointestinal anormal.
CN111606846A (zh) * 2020-05-12 2020-09-01 广州理文科技有限公司 一种n`-三氟甲磺酰基n杂芳香胺类化合物及其制备方法
WO2025058459A1 (ko) * 2023-09-15 2025-03-20 (주)휴온스 신규한 이미다조피리딘계 화합물 및 이를 유효성분으로 포함하는 위장관 염증질환 또는 위산-관련 질환의 예방, 개선 또는 치료용 조성물

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA81219B (en) * 1980-01-23 1982-01-27 Schering Corp Imidazo (1,2-a) pyridines ,process for their preparation and pharmaceutical compositions containing them
DE3269604D1 (en) * 1981-06-26 1986-04-10 Schering Corp Novel imidazo(1,2-a)pyridines and pyrazines, processes for their preparation and pharmaceutical compositions containing them
US4725601A (en) * 1985-06-04 1988-02-16 Fujisawa Pharmaceutical Co., Ltd. Certain imidazo[1,2-a]pyridines useful in the treatment of ulcers
US5574042A (en) * 1992-11-02 1996-11-12 Fujisawa Pharmaceutical Co., Ltd Imidazo [1,2-a] pyridines and their pharmaceutical use
IL108520A (en) * 1993-02-15 1997-09-30 Byk Gulden Lomberg Chem Fab 2, 3, 8-TRISUBSTITUTED IMIDAZO £1, 2-a| PYRIDINE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
WO1994024130A1 (de) * 1993-04-22 1994-10-27 Byk Gulden Lomberg Chemische Fabrik Gmbh Neue pyridiniumsalze und ihre verwendung zur bekämpfung von helicobacter-bakterien
UA48122C2 (uk) * 1993-10-11 2002-08-15 Бік Гульден Ломберг Хеміше Фабрік Гмбх АЛКОКСІАЛКІЛКАРБАМАТИ ІМІДАЗО[1,2-а]ПІРИДИНІВ, СПОСІБ ЇХ ОДЕРЖАННЯ ТА ЛІКАРСЬКИЙ ЗАСІБ НА ЇХ ОСНОВІ
NZ290818A (en) 1994-07-28 1998-10-28 Byk Gulden Lomberg Chem Fab Benzyl-imidazopyridines
CA2196076A1 (en) 1994-07-28 1996-02-08 Gerhard Grundler Acyl imidazopyridines
SK197A3 (en) * 1994-07-28 1997-06-04 Byk Gulden Lomberg Chem Fab Imidazopyridine-azolidinones, preparation method thereof, pharmaceutical composition containing same and their use
AU3221795A (en) 1994-07-28 1996-02-22 Byk Gulden Lomberg Chemische Fabrik Gmbh Halogenated imidazopyridines
DE19602853A1 (de) * 1996-01-26 1997-07-31 Byk Gulden Lomberg Chem Fab Neue Halogenimidazopyridine
US6096758A (en) 1996-01-26 2000-08-01 Byk Gulden Lomberg Chemische Fabrik Gmbh 3-methylimidazopyridines
SE9700661D0 (sv) * 1997-02-25 1997-02-25 Astra Ab New compounds
SE9801526D0 (sv) * 1998-04-29 1998-04-29 Astra Ab New compounds
SE9802793D0 (sv) * 1998-08-21 1998-08-21 Astra Ab New compounds
SE9802794D0 (sv) * 1998-08-21 1998-08-21 Astra Ab New compounds

Also Published As

Publication number Publication date
US6790960B2 (en) 2004-09-14
US6579884B1 (en) 2003-06-17
SI1105391T1 (en) 2005-02-28
NO20010860D0 (no) 2001-02-20
DE69921483T2 (de) 2006-02-02
ZA200100913B (en) 2002-05-02
ES2229763T3 (es) 2005-04-16
EP1411056A3 (en) 2004-04-28
IL141166A0 (en) 2002-02-10
WO2000011000A3 (en) 2000-06-15
EP1411056A2 (en) 2004-04-21
SE9802794D0 (sv) 1998-08-21
US20030220364A1 (en) 2003-11-27
DE69921483D1 (de) 2004-12-02
AU5767999A (en) 2000-03-14
PT1105391E (pt) 2005-01-31
EP1105391B1 (en) 2004-10-27
BR9913103A (pt) 2001-05-08
ATE280768T1 (de) 2004-11-15
US20050154007A1 (en) 2005-07-14
WO2000011000A2 (en) 2000-03-02
KR20010072798A (ko) 2001-07-31
CN1329613A (zh) 2002-01-02
CA2339286A1 (en) 2000-03-02
AR020226A1 (es) 2002-05-02
NO20010860L (no) 2001-04-23
JP2002523415A (ja) 2002-07-30
EP1105391A2 (en) 2001-06-13

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