PT100756A - Novos derivados de gangliosidos, processo para a sua preparacao e composicoes farmaceuticas que os contem - Google Patents
Novos derivados de gangliosidos, processo para a sua preparacao e composicoes farmaceuticas que os contemInfo
- Publication number
- PT100756A PT100756A PT100756A PT10075692A PT100756A PT 100756 A PT100756 A PT 100756A PT 100756 A PT100756 A PT 100756A PT 10075692 A PT10075692 A PT 10075692A PT 100756 A PT100756 A PT 100756A
- Authority
- PT
- Portugal
- Prior art keywords
- ganglioside
- lyso
- gangliosides
- acyl
- contain
- Prior art date
Links
- 150000002270 gangliosides Chemical class 0.000 title abstract 6
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- KXDHJXZQYSOELW-UHFFFAOYSA-N Carbamic acid Chemical compound NC(O)=O KXDHJXZQYSOELW-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- -1 aliphatic amino acid Chemical class 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000001735 carboxylic acids Chemical class 0.000 abstract 1
- 210000000653 nervous system Anatomy 0.000 abstract 1
- 230000007170 pathology Effects 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000000542 sulfonic acid group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
- C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITPD910139A IT1253832B (it) | 1991-08-01 | 1991-08-01 | Derivati di gangliosidi |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT100756A true PT100756A (pt) | 1993-09-30 |
| PT100756B PT100756B (pt) | 1999-10-29 |
Family
ID=11389659
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT100756A PT100756B (pt) | 1991-08-01 | 1992-07-31 | Novos derivados de gangliosidos, processo para a sua preparacao e composicoes farmaceuticas que os contem |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5350841A (pt) |
| EP (1) | EP0599908B1 (pt) |
| JP (1) | JPH06509350A (pt) |
| AT (1) | ATE150028T1 (pt) |
| AU (1) | AU2426592A (pt) |
| DE (1) | DE69218222T2 (pt) |
| ES (1) | ES2100360T3 (pt) |
| IT (1) | IT1253832B (pt) |
| PT (1) | PT100756B (pt) |
| WO (1) | WO1993003049A1 (pt) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6407072B1 (en) * | 1988-12-02 | 2002-06-18 | Fidia S.P.A. | Lysoganglioside derivatives |
| IT1232175B (it) * | 1989-07-27 | 1992-01-25 | Fidia Farmaceutici | Analoghi semisintetici di gangliosidi |
| IT1254280B (it) * | 1992-03-13 | 1995-09-14 | Fidia Spa | Composizioni farmaceutiche comprendenti monosialoganglioside gm1 o un suo derivato atte al trattamento della malattia di parkinson |
| US5849717A (en) * | 1993-03-04 | 1998-12-15 | Fidia S.P.A. | O-sulfated gangliosides and lyso-ganglioside derivatives |
| IT1267955B1 (it) * | 1993-03-04 | 1997-02-18 | Fidia S P A In Amministrazione | Derivati solfatati dei lisogangliosidi |
| IT1267956B1 (it) * | 1993-03-04 | 1997-02-18 | Fidia S P A In Amministrazione | Derivati o-solfatati di gangliosidi e lisogangliosidi |
| US5795869A (en) * | 1993-03-04 | 1998-08-18 | Fidia S.P.A. | Sulfated lyso-ganglioside derivatives |
| US5789561A (en) * | 1995-12-18 | 1998-08-04 | Daikin Industries Ltd. | Fluorine-substituted ganglioside GM3 derivative and intermediates therefor |
| MXPA04001831A (es) | 2001-08-29 | 2004-07-08 | Neose Technologies Inc | Nuevos derivados sinteticos de gangliosidos y composiciones de los mismos. |
| JP2006519878A (ja) | 2003-03-06 | 2006-08-31 | ネオーズ テクノロジーズ， インコーポレイテッド | ガングリオシドの酵素合成のための方法および化合物 |
| EP2410846B1 (en) * | 2009-03-25 | 2016-09-07 | Seneb Biosciences, Inc. | Glycolipids as treatment for disease |
| WO2023102665A1 (en) * | 2021-12-09 | 2023-06-15 | The Governors Of The University Of Alberta | Cellular and tissue clearance of misfolded proteins and uses thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1199116B (it) * | 1984-07-03 | 1988-12-30 | Fidia Farmaceutici | Derivati di gangliosidi |
| IT1235161B (it) * | 1988-12-02 | 1992-06-22 | Fidia Farmaceutici | Derivati di lisogangliosidi |
| IT1232175B (it) * | 1989-07-27 | 1992-01-25 | Fidia Farmaceutici | Analoghi semisintetici di gangliosidi |
| IT1232176B (it) * | 1989-07-27 | 1992-01-25 | Fidia Farmaceutici | Derivati di-lisogangliosidi |
| IT1238346B (it) * | 1989-11-14 | 1993-07-13 | Gangliosidi modificati e loro derivati funzionali. |
-
1991
- 1991-08-01 IT ITPD910139A patent/IT1253832B/it active IP Right Grant
-
1992
- 1992-07-31 PT PT100756A patent/PT100756B/pt not_active IP Right Cessation
- 1992-07-31 US US07/922,383 patent/US5350841A/en not_active Expired - Lifetime
- 1992-08-01 JP JP5503281A patent/JPH06509350A/ja active Pending
- 1992-08-01 ES ES92917164T patent/ES2100360T3/es not_active Expired - Lifetime
- 1992-08-01 EP EP92917164A patent/EP0599908B1/en not_active Expired - Lifetime
- 1992-08-01 WO PCT/EP1992/001776 patent/WO1993003049A1/en not_active Ceased
- 1992-08-01 DE DE69218222T patent/DE69218222T2/de not_active Expired - Fee Related
- 1992-08-01 AT AT92917164T patent/ATE150028T1/de not_active IP Right Cessation
- 1992-08-01 AU AU24265/92A patent/AU2426592A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ATE150028T1 (de) | 1997-03-15 |
| ITPD910139A0 (it) | 1991-08-01 |
| EP0599908B1 (en) | 1997-03-12 |
| DE69218222T2 (de) | 1997-10-09 |
| WO1993003049A1 (en) | 1993-02-18 |
| ES2100360T3 (es) | 1997-06-16 |
| DE69218222D1 (de) | 1997-04-17 |
| PT100756B (pt) | 1999-10-29 |
| IT1253832B (it) | 1995-08-29 |
| EP0599908A1 (en) | 1994-06-08 |
| AU2426592A (en) | 1993-03-02 |
| JPH06509350A (ja) | 1994-10-20 |
| US5350841A (en) | 1994-09-27 |
| ITPD910139A1 (it) | 1993-02-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BB1A | Laying open of patent application |
Effective date: 19930507 |
|
| FG3A | Patent granted, date of granting |
Effective date: 19990705 |
|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20010131 |