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PL91735B1 - 4-Ethers of 3-amino-5-sulfamoylbenzoic acids [US3939267A] - Google Patents

4-Ethers of 3-amino-5-sulfamoylbenzoic acids [US3939267A] Download PDF

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Publication number
PL91735B1
PL91735B1 PL1973174742A PL17474273A PL91735B1 PL 91735 B1 PL91735 B1 PL 91735B1 PL 1973174742 A PL1973174742 A PL 1973174742A PL 17474273 A PL17474273 A PL 17474273A PL 91735 B1 PL91735 B1 PL 91735B1
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PL
Poland
Prior art keywords
salt
formula
group
amino
carboxyl group
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Application number
PL1973174742A
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English (en)
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Publication of PL91735B1 publication Critical patent/PL91735B1/pl

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • C07C311/38—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton
    • C07C311/39—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Claims (3)

  1. Zastrzezenia patentowe 1. Sposób wytwarzania nowych 4-fenyloeterów kwasów 3-amino-5-sulfamoHo-benzoesowych o ogólnym wzorze 1, w którym R oznacza rodnik alkilowy lub elkenylowy, o 4,lub 5 atomach wegla, rodnik cyklopropylo- metylowy, benzylowy lub furfurylowy, a X oznacza atom tlenu lub siarki, oraz soli tych zwiazków, znamien¬ ny tym, ze w zwiazku o ogólnym wzorze 2, w którym R i X maja wyzej podane znaczenie, a Z oznacza grupe karbamoiIowa lub karbazoitowa albo w jego soli lub N-acylowej pochodnej, przeprowadza sie grupe Z na drodze hydrolizy w grupe karboksylowa lub w wystepujaca w postaci soli grupe karboksylowa, i otrzymany wolny zwiazek ewentualnie przeksztalca sie w sól albo otrzymana sól ewentualnie przeksztalca sie w wolny zwiazek lub w inna sól i/lub otrzymana mieszanine izomerów lub racematów ewentualnie rozdziela sie na poszczególne izomery lub racematy, i/lub otrzymane racematy ewentualnie rozszczepia sie na enancjomery.
  2. 2. Sposób, wedlug zastrz. 1, znamienny tym, ze grupe Z substancji wyjsciowej przeprowadza sie na drodze traktowania wodnymi roztworami zasad w grupe karboksylowa lub w wystepujaca w postaci soli grupe karboksylowa.
  3. 3. Sposób, wedlug zastrz. 1, znamienny tym, ze jako substancje wyjsciowa stosuje sie amid lub hydrazyd kwasu 4-/4-amino-fenylotio/-3-n-butyloamino-5-sulfamoilo-benzoesowego lub ich nizsza N-elkanoilowa pochodna.91735 R-HN H,N COOH 2^^x-V S02NH2 Wzór i R-HN H2N ^—X S02NH2 R Wzór 2 m^yZ" Hal ¦y S02NH2 Wzór 3 PL
PL1973174742A 1972-10-13 1973-10-11 4-Ethers of 3-amino-5-sulfamoylbenzoic acids [US3939267A] PL91735B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/297,530 US3939267A (en) 1972-10-13 1972-10-13 4-Ethers of 3-amino-5-sulfamoylbenzoic acids

Publications (1)

Publication Number Publication Date
PL91735B1 true PL91735B1 (en) 1977-03-31

Family

ID=23146696

Family Applications (2)

Application Number Title Priority Date Filing Date
PL1973174743A PL91762B1 (en) 1972-10-13 1973-10-11 4-Ethers of 3-amino-5-sulfamoylbenzoic acids [US3939267A]
PL1973174742A PL91735B1 (en) 1972-10-13 1973-10-11 4-Ethers of 3-amino-5-sulfamoylbenzoic acids [US3939267A]

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL1973174743A PL91762B1 (en) 1972-10-13 1973-10-11 4-Ethers of 3-amino-5-sulfamoylbenzoic acids [US3939267A]

Country Status (4)

Country Link
US (1) US3939267A (pl)
BE (1) BE805999A (pl)
PL (2) PL91762B1 (pl)
ZA (2) ZA735959B (pl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4093735A (en) * 1974-04-25 1978-06-06 Hoechst Aktiengesellschaft 5-Sulfamoylbenzoic acid derivatives carrying a heterocyclic substituent
DE2419970C3 (de) * 1974-04-25 1980-06-12 Hoechst Ag, 6000 Frankfurt 3-<l-Pyrrolidinyl)-4-phenoxy-5sulfamoylbenzoesäure und Verfahren zu ihrer Herstellung
CH628622A5 (de) * 1976-12-24 1982-03-15 Ciba Geigy Ag Verfahren zur herstellung von neuen in 4-stellung substituierten 3-sulfamoylbenzoesaeuren.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3163645A (en) * 1964-09-25 1964-12-29 Ciba Geigy Corp Derivatives of 3, 4-dihydro-2-h-[1, 2, 4]-benzothiadiazine-1, 1-dioxides
GB1249490A (en) * 1968-12-24 1971-10-13 Leo Pharm Prod Ltd New sulphamyl-benzoic acid derivatives

Also Published As

Publication number Publication date
US3939267A (en) 1976-02-17
PL91762B1 (en) 1977-03-31
ZA735959B (en) 1974-08-28
ZA737959B (en) 1974-08-28
BE805999A (fr) 1974-04-12

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