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PL3532607T3 - Restymulacja kriokonserwowanych limfocytów naciekających guza nowotworowego - Google Patents

Restymulacja kriokonserwowanych limfocytów naciekających guza nowotworowego

Info

Publication number
PL3532607T3
PL3532607T3 PL17798045.5T PL17798045T PL3532607T3 PL 3532607 T3 PL3532607 T3 PL 3532607T3 PL 17798045 T PL17798045 T PL 17798045T PL 3532607 T3 PL3532607 T3 PL 3532607T3
Authority
PL
Poland
Prior art keywords
industrating
restimulation
cryo
lymphocytes
preserved
Prior art date
Application number
PL17798045.5T
Other languages
English (en)
Inventor
Ian FRANK
Michael T. Lotze
Original Assignee
Iovance Biotherapeutics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Iovance Biotherapeutics, Inc. filed Critical Iovance Biotherapeutics, Inc.
Publication of PL3532607T3 publication Critical patent/PL3532607T3/pl

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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/16—Physical preservation processes
    • A01N1/162—Temperature processes, e.g. following predefined temperature changes over time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/31—Chimeric antigen receptors [CAR]
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    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A61K40/4271—Melanoma antigens
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • G—PHYSICS
    • G01—MEASURING; TESTING
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
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    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
    • A61K2239/57—Skin; melanoma
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    • C07K2319/00—Fusion polypeptide
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    • C07K2319/00—Fusion polypeptide
    • C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/04—Immunosuppressors, e.g. cyclosporin, tacrolimus
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C12N2501/2302—Interleukin-2 (IL-2)
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    • C12N2502/1121—Dendritic cells
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    • C12N2502/11—Coculture with; Conditioned medium produced by blood or immune system cells
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    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/99—Coculture with; Conditioned medium produced by genetically modified cells

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PL17798045.5T 2016-10-26 2017-10-26 Restymulacja kriokonserwowanych limfocytów naciekających guza nowotworowego PL3532607T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201662413283P 2016-10-26 2016-10-26
US201662413387P 2016-10-26 2016-10-26
US201662415452P 2016-10-31 2016-10-31
PCT/US2017/058610 WO2018081473A1 (en) 2016-10-26 2017-10-26 Restimulation of cryopreserved tumor infiltrating lymphocytes

Publications (1)

Publication Number Publication Date
PL3532607T3 true PL3532607T3 (pl) 2024-07-01

Family

ID=60327390

Family Applications (1)

Application Number Title Priority Date Filing Date
PL17798045.5T PL3532607T3 (pl) 2016-10-26 2017-10-26 Restymulacja kriokonserwowanych limfocytów naciekających guza nowotworowego

Country Status (24)

Country Link
US (22) US11026974B2 (pl)
EP (2) EP4180520A1 (pl)
JP (2) JP2019532652A (pl)
KR (2) KR20190066073A (pl)
CN (1) CN110099998A (pl)
AU (1) AU2017347851B2 (pl)
BR (1) BR112019008305A2 (pl)
CA (1) CA3041678A1 (pl)
DK (1) DK3532607T3 (pl)
ES (1) ES2977118T3 (pl)
FI (1) FI3532607T3 (pl)
HR (1) HRP20240436T1 (pl)
HU (1) HUE066460T2 (pl)
IL (1) IL266209B2 (pl)
LT (1) LT3532607T (pl)
MD (1) MD3532607T2 (pl)
MX (2) MX2019004707A (pl)
PL (1) PL3532607T3 (pl)
PT (1) PT3532607T (pl)
RS (1) RS65448B1 (pl)
SG (1) SG11201903331QA (pl)
SI (1) SI3532607T1 (pl)
SM (1) SMT202400133T1 (pl)
WO (1) WO2018081473A1 (pl)

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