PL310896A1 - Cyclic compounds useful as platelet iib/iiia glycoprotein inhibitors - Google Patents

Cyclic compounds useful as platelet iib/iiia glycoprotein inhibitors

Info

Publication number: PL310896A1
Authority: PL; Poland
Prior art keywords: compounds useful; cyclic compounds; glycoprotein inhibitors; platelet iib; iiia glycoprotein
Prior art date: 1993-03-29

Application number

PL94310896A

Inventor

William Frank Degrado

Sharon Anne Jackson

Shaker Ahmed Mousa

Anju Parthasarathy

Michael Sworin

Maria Rafalski

Original Assignee

Du Pont Merck Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-03-29

Filing date

1994-03-28

Publication date

1996-01-08

1994-03-28 Application filed by Du Pont Merck Pharma filed Critical Du Pont Merck Pharma

1996-01-08 Publication of PL310896A1 publication Critical patent/PL310896A1/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/75—Fibrinogen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Hematology (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Zoology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Diabetes (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Toxicology (AREA)
Chemical Kinetics & Catalysis (AREA)
Gastroenterology & Hepatology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

PL94310896A 1993-03-29 1994-03-28 Cyclic compounds useful as platelet iib/iiia glycoprotein inhibitors PL310896A1 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US3844893A	1993-03-29	1993-03-29

Publications (1)

Publication Number	Publication Date
PL310896A1 true PL310896A1 (en)	1996-01-08

Family

ID=21900014

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL94310896A PL310896A1 (en)	1993-03-29	1994-03-28	Cyclic compounds useful as platelet iib/iiia glycoprotein inhibitors

Country Status (10)

Country	Link
EP (1)	EP0691987A1 (en)
JP (1)	JPH08508498A (en)
AU (1)	AU6415894A (en)
CA (1)	CA2159070A1 (en)
FI (1)	FI954556A0 (en)
HU (1)	HUT72896A (en)
NO (1)	NO953832L (en)
NZ (1)	NZ263456A (en)
PL (1)	PL310896A1 (en)
WO (1)	WO1994022910A1 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2126748T3 (en) *	1993-03-29	1999-04-01	Du Pont Merck Pharma	PROCESS AND INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF PLATELET GLYCOPROTEIN INHIBITORS II B / III A.
US5879657A (en) *	1993-03-30	1999-03-09	The Dupont Merck Pharmaceutical Company	Radiolabeled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders
AP1390A (en) *	1996-11-27	2005-04-15	Aventis Pharmaceuticals Products Inc	Pharmaceutical composition comprising a compound having anti-Xa activity and a platelet aggregation antagonist compound.
US6010911A (en) *	1997-04-30	2000-01-04	Medtronic, Inc.	Apparatus for performing a heparin-independent high sensitivity platelet function evaluation technique
US6537520B1 (en)	1998-03-31	2003-03-25	Bristol-Myers Squibb Pharma Company	Pharmaceuticals for the imaging of angiogenic disorders
GB0623607D0 (en)	2006-11-27	2007-01-03	Haemostatix Ltd	Tissue adhesive
PL2118123T3 (en)	2007-01-31	2016-06-30	Dana Farber Cancer Inst Inc	Stabilized p53 peptides and uses thereof
KR101525754B1 (en)	2007-03-28	2015-06-09	프레지던트 앤드 펠로우즈 오브 하바드 칼리지	Stitched polypeptides
ES2730927T3 (en)	2009-11-10	2019-11-13	Allegro Pharmaceuticals Llc	Compositions and methods to inhibit cell adhesion or direct diagnostic or therapeutic agents to GDD binding sites
US11673914B2 (en)	2009-11-10	2023-06-13	Allegro Pharmaceuticals, LLC	Peptide therapies for reduction of macular thickening
CA2807685C (en)	2010-08-13	2020-10-06	Aileron Therapeutics, Inc.	P53 derived peptidomimetic macrocycle
ES2820855T3 (en)	2011-05-09	2021-04-22	Allegro Pharmaceuticals Llc	Integrin receptor antagonists and their methods of use
TW201806968A (en)	2011-10-18	2018-03-01	艾利倫治療公司	Peptidomimetic macrocycles
BR112014020103A2 (en)	2012-02-15	2018-10-09	Aileron Therapeutics, Inc.	peptidomimetic macrocycles
CA2864120A1 (en)	2012-02-15	2013-08-22	Aileron Therapeutics, Inc.	Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles
KR20150082307A (en)	2012-11-01	2015-07-15	에일러론 테라퓨틱스 인코포레이티드	Disubstituted amino acids and methods of preparation and use thereof
SG10201902598VA (en)	2014-09-24	2019-04-29	Aileron Therapeutics Inc	Peptidomimetic macrocycles and formulations thereof
MX2017003797A (en)	2014-09-24	2017-06-15	Aileron Therapeutics Inc	Peptidomimetic macrocycles and uses thereof.
US10253067B2 (en)	2015-03-20	2019-04-09	Aileron Therapeutics, Inc.	Peptidomimetic macrocycles and uses thereof
CN108368161A (en)	2015-09-10	2018-08-03	艾瑞朗医疗公司	Peptidomimetic macrocyclic compound as MCL-1 conditioning agents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2636066B1 (en) *	1988-09-02	1991-10-25	Centre Nat Rech Scient	CYCLOPEPTIDE DERIVATIVES FOR USE AS SELECTIVE INHIBITORS AGAINST ACTIVE SERINE PROTEASES
US5384309A (en) *	1989-07-17	1995-01-24	Genentech, Inc.	Cyclized peptides and their use as platelet aggregation inhibitors
AU6470590A (en) *	1989-10-23	1991-04-26	Smithkline Beecham Corporation	Cyclic anti-aggregatory peptides
IL103252A (en) *	1991-09-30	1997-03-18	Du Pont Merck Pharma	CYCLIC COMPOUNDS USEFUL AS INHIBITORS OF PLATELET GLYCOPROTEIN IIb/IIIa AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

1994
- 1994-03-28 AU AU64158/94A patent/AU6415894A/en not_active Abandoned
- 1994-03-28 FI FI954556A patent/FI954556A0/en unknown
- 1994-03-28 PL PL94310896A patent/PL310896A1/en unknown
- 1994-03-28 WO PCT/US1994/003223 patent/WO1994022910A1/en not_active Ceased
- 1994-03-28 CA CA002159070A patent/CA2159070A1/en not_active Abandoned
- 1994-03-28 HU HU9502832A patent/HUT72896A/en unknown
- 1994-03-28 JP JP6522195A patent/JPH08508498A/en not_active Ceased
- 1994-03-28 EP EP94911703A patent/EP0691987A1/en not_active Withdrawn
- 1994-03-28 NZ NZ263456A patent/NZ263456A/en not_active IP Right Cessation
1995
- 1995-09-28 NO NO953832A patent/NO953832L/en unknown

Also Published As

Publication number	Publication date
CA2159070A1 (en)	1994-10-13
FI954556L (en)	1995-09-26
NO953832D0 (en)	1995-09-28
EP0691987A1 (en)	1996-01-17
NO953832L (en)	1995-11-28
FI954556A7 (en)	1995-09-26
AU6415894A (en)	1994-10-24
FI954556A0 (en)	1995-09-26
HUT72896A (en)	1996-06-28
HU9502832D0 (en)	1995-11-28
NZ263456A (en)	1996-11-26
JPH08508498A (en)	1996-09-10
WO1994022910A1 (en)	1994-10-13

Publication	Publication Date	Title
PL310896A1 (en)	1996-01-08	Cyclic compounds useful as platelet iib/iiia glycoprotein inhibitors
FI943478A7 (en)	1995-01-23	Glycoprotein IIb/IIIa antagonists
FI941457L (en)	1994-03-29	Cyclic compounds useful as inhibitors of platelet glycoprotein IIb/IIIa
ZA93550B (en)	1994-07-26	Azabricyclic compounds as calcium channel antagonists
AU3364493A (en)	1993-09-01	Compounds as calcium channel antagonists
GB9420114D0 (en)	1994-11-16	Substituted cyclic derivatives as novel antidegenerative agents
EP0574494A4 (en)	1994-07-06	Indoles useful as platelet activating factor antagonists
GB9317967D0 (en)	1993-10-13	Improvements relating to plasics articles
ITMI932056A1 (en)	1995-03-27	LOCK FOR CONTAINERS SUCH AS BAGS OR SIMILAR
SG44770A1 (en)	1997-12-19	Cyclic compounds
GB9311870D0 (en)	1993-07-28	Ties
ZA927515B (en)	1994-03-30	Cyclic compounds useful as inhibitors of platelet glycoprotein IIb/IIIa
GB9302261D0 (en)	1993-03-24	Improvements relating to packaging
HUT70277A (en)	1995-09-28	New packaging/containerization system
HUT66649A (en)	1994-12-28	Containerization packaging system
HUT70279A (en)	1995-09-28	New packaging containerization system
GB2257958B (en)	1995-03-15	Improvements relating to packaging
GB9312411D0 (en)	1993-07-28	Stabilisers for cycles
GB2280658B (en)	1996-12-18	Improvements relating to containers
GB9302651D0 (en)	1993-03-24	Improvements relating to containers
ITAR920017A0 (en)	1992-07-02	COMPOSITE BOX FOR SEEDLING CONTAINERS
GB9321861D0 (en)	1993-12-15	Platelet derived growth factor analogues
GB9318547D0 (en)	1993-10-20	Improvements relating to packaging containers
GB9318882D0 (en)	1993-10-27	Improvements relating to containers
GB9305150D0 (en)	1993-04-28	Improvements relating to containers