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PL2970378T3 - Chromatografia oddziaływań hydrofobowych białek w warunkach bez soli - Google Patents

Chromatografia oddziaływań hydrofobowych białek w warunkach bez soli

Info

Publication number
PL2970378T3
PL2970378T3 PL14765488T PL14765488T PL2970378T3 PL 2970378 T3 PL2970378 T3 PL 2970378T3 PL 14765488 T PL14765488 T PL 14765488T PL 14765488 T PL14765488 T PL 14765488T PL 2970378 T3 PL2970378 T3 PL 2970378T3
Authority
PL
Poland
Prior art keywords
hydrophobic interaction
chromatography under
salt conditions
interaction protein
protein chromatography
Prior art date
Application number
PL14765488T
Other languages
English (en)
Inventor
Sanchayita Ghose
Yinying TAO
Original Assignee
Biogen Ma Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51537906&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2970378(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biogen Ma Inc. filed Critical Biogen Ma Inc.
Publication of PL2970378T3 publication Critical patent/PL2970378T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/20Partition-, reverse-phase or hydrophobic interaction chromatography
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065Purification, fragmentation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
PL14765488T 2013-03-15 2014-03-15 Chromatografia oddziaływań hydrofobowych białek w warunkach bez soli PL2970378T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361791238P 2013-03-15 2013-03-15
EP14765488.3A EP2970378B1 (en) 2013-03-15 2014-03-15 Hydrophobic interaction protein chromatography under no-salt conditions
PCT/US2014/029930 WO2014145208A1 (en) 2013-03-15 2014-03-15 Hydrophobic interaction protein chromatography under no-salt conditions

Publications (1)

Publication Number Publication Date
PL2970378T3 true PL2970378T3 (pl) 2021-12-06

Family

ID=51537906

Family Applications (1)

Application Number Title Priority Date Filing Date
PL14765488T PL2970378T3 (pl) 2013-03-15 2014-03-15 Chromatografia oddziaływań hydrofobowych białek w warunkach bez soli

Country Status (6)

Country Link
US (3) US9994609B2 (pl)
EP (2) EP2970378B1 (pl)
JP (1) JP6592426B2 (pl)
DK (1) DK2970378T3 (pl)
PL (1) PL2970378T3 (pl)
WO (1) WO2014145208A1 (pl)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10023608B1 (en) 2013-03-13 2018-07-17 Amgen Inc. Protein purification methods to remove impurities
DK2970378T3 (da) * 2013-03-15 2021-08-23 Biogen Ma Inc Hydrofob interaktionsproteinkromatografi under saltfrie betingelser
EP3114455B1 (en) * 2014-03-04 2020-01-15 Merck Patent GmbH Robust antibody purification
TW201628649A (zh) 2014-10-09 2016-08-16 再生元醫藥公司 減少醫藥調配物中微可見顆粒之方法
IL264631B2 (en) 2016-08-16 2024-05-01 Regeneron Pharma A method for quantifying individual antibodies from a mixture
EA201990986A1 (ru) 2016-10-25 2019-09-30 Ридженерон Фармасьютикалз, Инк. Способы и системы анализа хроматографических данных
EP3824906A1 (en) 2016-12-21 2021-05-26 Amgen Inc. Anti-tnf alpha antibody formulations
JP7301043B2 (ja) 2017-09-19 2023-06-30 リジェネロン・ファーマシューティカルズ・インコーポレイテッド 粒子の形成を低減する方法及びそれにより形成される組成物
TWI853823B (zh) 2018-07-02 2024-09-01 美商里珍納龍藥品有限公司 自混合物製備多肽之系統及方法

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5641870A (en) 1995-04-20 1997-06-24 Genentech, Inc. Low pH hydrophobic interaction chromatography for antibody purification
WO2005042569A1 (en) 2003-10-24 2005-05-12 Amgen, Inc. Process for purifying proteins in a hydrophobic interaction chromatography flow-through fraction
WO2005075498A1 (en) 2004-01-30 2005-08-18 Amgen Inc. Process for purifying proteins
KR101243601B1 (ko) 2004-10-21 2013-03-20 지이 헬스케어 바이오-사이언시스 에이비 크로마토그래피 리간드
US7408030B2 (en) 2005-01-13 2008-08-05 North Carolina State University Purification of immunoglobulins using affinity chromatography and peptide ligands
CN101384623B (zh) * 2005-12-22 2013-07-24 常山凯捷健生物药物研发(河北)有限公司 白蛋白与治疗剂的预成型偶联物的制备方法
EP2436696B8 (en) 2007-01-05 2017-12-13 University of Zurich Anti-beta-amyloid antibody and uses thereof
EP2114984A2 (en) 2007-01-17 2009-11-11 Merck Serono S.A. Process for the purification of fc-containing proteins
EP2321348A2 (en) 2008-07-09 2011-05-18 University of Zürich Method of promoting neurogenesis
WO2010005570A2 (en) 2008-07-09 2010-01-14 Biogen Idec Ma Inc. Compositions comprising antibodies to lingo or fragments thereof
US8497358B2 (en) 2008-12-19 2013-07-30 Takeda Pharmaceutical Company Limited Antibody purification method
US20120202976A1 (en) 2009-10-12 2012-08-09 Ge Healthcare Bio-Sciences Ab Separation matrices
KR101830596B1 (ko) 2009-10-20 2018-02-22 애브비 인코포레이티드 단백질 a 친화성 크로마토그래피를 사용한 항―il―13 항체의 분리 및 정제
JP5699429B2 (ja) * 2009-12-18 2015-04-08 東ソー株式会社 Fcレセプターの精製方法
CN103429609A (zh) 2010-12-08 2013-12-04 安姆根有限公司 在氨基酸存在下的离子交换层析
KR20140033126A (ko) 2011-06-16 2014-03-17 디에스엠 아이피 어셋츠 비.브이. 단일 유닛 크로마토그래피 항체 정제
LT2723379T (lt) 2011-06-23 2018-10-25 Biogen International Neuroscience Gmbh Anti-alfa sinukleiną rišančios molekulės
US9334319B2 (en) * 2012-04-20 2016-05-10 Abbvie Inc. Low acidic species compositions
WO2013176754A1 (en) 2012-05-24 2013-11-28 Abbvie Inc. Novel purification of antibodies using hydrophobic interaction chromatography
CN104797332B (zh) 2012-11-13 2018-05-29 通用电气医疗集团生物工艺研发股份公司 多元阴离子交换基质
DK2970378T3 (da) 2013-03-15 2021-08-23 Biogen Ma Inc Hydrofob interaktionsproteinkromatografi under saltfrie betingelser
JP2016519144A (ja) 2013-05-13 2016-06-30 メディミューン,エルエルシー 最小限の単量体の分離を伴う組換えポリクローナル多量体の分離
AR097651A1 (es) 2013-09-13 2016-04-06 Genentech Inc Métodos y composiciones que comprenden polipéptidos recombinantes purificados
CN106459200B (zh) * 2014-03-21 2019-12-06 艾伯维公司 抗-egfr抗体及抗体药物偶联物

Also Published As

Publication number Publication date
WO2014145208A1 (en) 2014-09-18
US20230391820A1 (en) 2023-12-07
US11111269B2 (en) 2021-09-07
EP2970378A4 (en) 2016-11-16
EP2970378A1 (en) 2016-01-20
EP2970378B1 (en) 2021-05-26
US20190144495A1 (en) 2019-05-16
JP6592426B2 (ja) 2019-10-16
US20160024145A1 (en) 2016-01-28
EP3936515A1 (en) 2022-01-12
DK2970378T3 (da) 2021-08-23
US9994609B2 (en) 2018-06-12
JP2016515529A (ja) 2016-05-30

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