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PL2857039T3 - Środek terapeutyczny lub środek profilaktyczny na otępienie - Google Patents

Środek terapeutyczny lub środek profilaktyczny na otępienie

Info

Publication number
PL2857039T3
PL2857039T3 PL13797290T PL13797290T PL2857039T3 PL 2857039 T3 PL2857039 T3 PL 2857039T3 PL 13797290 T PL13797290 T PL 13797290T PL 13797290 T PL13797290 T PL 13797290T PL 2857039 T3 PL2857039 T3 PL 2857039T3
Authority
PL
Poland
Prior art keywords
agent
dementia
prophylactic
therapeutic agent
therapeutic
Prior art date
Application number
PL13797290T
Other languages
English (en)
Inventor
Hiroshi Mori
Takami Tomiyama
Yoichi Matsumoto
Hiroshi Eguchi
Yuichi Kunori
Original Assignee
Osaka City University
Teijin Pharma Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Osaka City University, Teijin Pharma Limited filed Critical Osaka City University
Publication of PL2857039T3 publication Critical patent/PL2857039T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711Alzheimer's disease; Amyloid plaque core protein
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
PL13797290T 2012-05-31 2013-05-30 Środek terapeutyczny lub środek profilaktyczny na otępienie PL2857039T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2012124336 2012-05-31
PCT/JP2013/065090 WO2013180238A1 (ja) 2012-05-31 2013-05-30 認知症治療剤又は予防剤
EP13797290.7A EP2857039B1 (en) 2012-05-31 2013-05-30 Therapeutic agent or prophylactic agent for dementia

Publications (1)

Publication Number Publication Date
PL2857039T3 true PL2857039T3 (pl) 2020-05-18

Family

ID=49673425

Family Applications (1)

Application Number Title Priority Date Filing Date
PL13797290T PL2857039T3 (pl) 2012-05-31 2013-05-30 Środek terapeutyczny lub środek profilaktyczny na otępienie

Country Status (30)

Country Link
US (3) US20150183854A1 (pl)
EP (2) EP3662931B1 (pl)
JP (3) JP5971659B2 (pl)
KR (2) KR102208283B1 (pl)
CN (1) CN104602708B (pl)
AR (1) AR091218A1 (pl)
AU (2) AU2013268364B2 (pl)
BR (1) BR112014029566A2 (pl)
CA (1) CA2875205C (pl)
CY (1) CY1122530T1 (pl)
DK (1) DK2857039T3 (pl)
ES (2) ES2973070T3 (pl)
HR (1) HRP20192267T1 (pl)
HU (1) HUE046919T2 (pl)
IL (1) IL235899B (pl)
LT (1) LT2857039T (pl)
ME (1) ME03587B (pl)
MX (1) MX361128B (pl)
MY (1) MY172458A (pl)
NZ (1) NZ630536A (pl)
PH (1) PH12014502669B1 (pl)
PL (1) PL2857039T3 (pl)
PT (1) PT2857039T (pl)
RS (1) RS59802B1 (pl)
RU (1) RU2657438C2 (pl)
SG (2) SG10201805410XA (pl)
SI (1) SI2857039T1 (pl)
TW (2) TWI700296B (pl)
WO (1) WO2013180238A1 (pl)
ZA (1) ZA201409186B (pl)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012106363A2 (en) 2011-01-31 2012-08-09 Intellect Neurosciences Inc. Treatment of tauopathies
EP2709728B1 (en) * 2011-05-20 2019-01-23 Oligomerix, Inc. Tau protease methods of use
SI2857039T1 (sl) * 2012-05-31 2020-03-31 Osaka City University Terapevtsko sredstvo ali profilaktično sredstvo za demenco
WO2014008404A1 (en) 2012-07-03 2014-01-09 Washington University Antibodies to tau
TW202136296A (zh) * 2014-06-27 2021-10-01 美商C2N醫療診斷有限責任公司 人類化抗-tau抗體
US20190224339A1 (en) * 2016-04-29 2019-07-25 Voyager Therapeutics, Inc. Compositions for the treatment of disease
JP6785372B2 (ja) * 2016-09-30 2020-11-18 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft 多重特異性分子の機能分析のためのsprに基づく二重結合アッセイ
KR20190134997A (ko) 2017-02-17 2019-12-05 데날리 테라퓨틱스 인크. 항-tau 항체 및 이의 사용 방법
JOP20180014A1 (ar) * 2017-02-27 2019-01-30 Teijin Pharma Ltd جسم مضاد متوافق مع البشر لعلاج أو الوقاية من الاضطرابات الإدراكية، وعملية لإنتاجه، وعامل لعلاج أو الوقاية من الاضطرابات الإدراكية باستخدامه
IL270971B2 (en) 2017-05-30 2024-06-01 Teijin Pharma Ltd Anti-igf-i receptor antibody
SG11202002575UA (en) 2017-10-02 2020-04-29 Merck Sharp & Dohme Chromane monobactam compounds for the treatment of bacterial infections
TWI750419B (zh) 2017-10-16 2021-12-21 日商衛材R&D企管股份有限公司 抗tau抗體及其用途
EP3778631A4 (en) 2018-04-06 2022-01-05 Teijin Pharma Limited Spns2 neutralizing antibody
JP7340794B2 (ja) * 2018-07-04 2023-09-08 学校法人 愛知医科大学 タウのスプライシングを制御するアンチセンスオリゴヌクレオチド及びその用途
CN110028583B (zh) * 2019-05-07 2020-09-11 温州医科大学 抗Tau抗体及其在治疗阿尔茨海默病、创伤性脑损伤中的应用
JP7429404B2 (ja) * 2019-08-06 2024-02-08 慶應義塾 タウ関連疾患モデルの製造方法
WO2021065306A1 (ja) 2019-09-30 2021-04-08 ニプロ株式会社 血液試料を検体とするタウタンパク質検出方法
US20230137434A1 (en) * 2020-03-19 2023-05-04 Vascular Biosciences CAR Peptide for Improved Coronavirus Survival
CA3183835A1 (en) 2020-06-25 2021-12-30 Jeanne E. Baker High affinity antibodies targeting tau phosphorylated at serine 413
US20250034559A1 (en) 2021-11-17 2025-01-30 Voyager Therapeutics, Inc. Compositions and methods for the treatment of tau-related disorders
KR20250069606A (ko) 2022-09-15 2025-05-19 보이저 테라퓨틱스, 인크. 타우 결합 화합물
WO2025122634A1 (en) 2023-12-05 2025-06-12 Voyager Therapeutics, Inc. Compositions and methods for the treatment of tau-related disorders

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS587390B2 (ja) 1975-03-11 1983-02-09 ツキシマキカイ カブシキガイシヤ ア−クヨウセツホウホウ
JP3587390B2 (ja) 1994-03-17 2004-11-10 タカラバイオ株式会社 リン酸化アミノ酸誘導体及びリン酸化ペプチド合成方法
WO1997034145A1 (fr) * 1996-03-13 1997-09-18 Mitsubishi Chemical Corporation Anticorps a proteine tau antiphosphorylee et procede de detection de la maladie d'alzheimer l'utilisant
US20080199471A1 (en) * 2002-03-01 2008-08-21 Bernett Matthew J Optimized cd40 antibodies and methods of using the same
US8012936B2 (en) * 2006-03-29 2011-09-06 New York University Tau fragments for immunotherapy
US20070280935A1 (en) * 2006-04-07 2007-12-06 Bernd Bohrmann Antibody that recognizes phosphorylated peptides
WO2007149293A2 (en) * 2006-06-16 2007-12-27 Envivo Pharmaceutical, Inc. Transgenic flies expressing tau and amyloid precursor fragment
UA107571C2 (xx) * 2009-04-03 2015-01-26 Фармацевтична композиція
EP4218794A3 (en) 2009-06-10 2023-09-13 New York University Immunological targeting of pathological tau proteins
US8609097B2 (en) 2009-06-10 2013-12-17 Hoffmann-La Roche Inc. Use of an anti-Tau pS422 antibody for the treatment of brain diseases
WO2012106363A2 (en) * 2011-01-31 2012-08-09 Intellect Neurosciences Inc. Treatment of tauopathies
TR201102696U (tr) * 2011-05-27 2011-06-21 Turhal Sal�H Bağlantısız hareketli ürün reklam standı.
SI2857039T1 (sl) * 2012-05-31 2020-03-31 Osaka City University Terapevtsko sredstvo ali profilaktično sredstvo za demenco
JOP20180014A1 (ar) * 2017-02-27 2019-01-30 Teijin Pharma Ltd جسم مضاد متوافق مع البشر لعلاج أو الوقاية من الاضطرابات الإدراكية، وعملية لإنتاجه، وعامل لعلاج أو الوقاية من الاضطرابات الإدراكية باستخدامه

Also Published As

Publication number Publication date
AU2018200413B2 (en) 2019-10-17
IL235899B (en) 2019-03-31
PT2857039T (pt) 2020-01-07
JP2018111716A (ja) 2018-07-19
KR20150027098A (ko) 2015-03-11
DK2857039T3 (da) 2019-12-16
CN104602708A (zh) 2015-05-06
ES2973070T3 (es) 2024-06-18
CY1122530T1 (el) 2021-01-27
JPWO2013180238A1 (ja) 2016-01-21
CN104602708B (zh) 2021-11-30
ES2763361T3 (es) 2020-05-28
SI2857039T1 (sl) 2020-03-31
RU2014153099A (ru) 2016-07-20
US20220340646A1 (en) 2022-10-27
MX2014014187A (es) 2015-06-04
RS59802B1 (sr) 2020-02-28
KR102208283B1 (ko) 2021-01-26
PH12014502669A1 (en) 2015-02-02
US20200148753A1 (en) 2020-05-14
LT2857039T (lt) 2020-03-10
WO2013180238A1 (ja) 2013-12-05
KR102133610B1 (ko) 2020-07-14
EP2857039A4 (en) 2015-08-26
IL235899A0 (en) 2015-01-29
EP3662931B1 (en) 2023-12-06
US20150183854A1 (en) 2015-07-02
JP2016147902A (ja) 2016-08-18
TW202041532A (zh) 2020-11-16
SG10201805410XA (en) 2018-08-30
AU2013268364B2 (en) 2018-02-08
JP5971659B2 (ja) 2016-08-17
EP3662931A1 (en) 2020-06-10
HK1210031A1 (en) 2016-04-15
AR091218A1 (es) 2015-01-21
BR112014029566A2 (pt) 2017-07-25
CA2875205A1 (en) 2013-12-05
ME03587B (me) 2020-07-20
ZA201409186B (en) 2015-12-23
HRP20192267T1 (hr) 2020-03-20
RU2657438C2 (ru) 2018-06-13
PH12014502669B1 (en) 2020-02-19
SG11201407878VA (en) 2015-01-29
AU2013268364A1 (en) 2014-12-18
EP2857039B1 (en) 2019-11-20
TWI777183B (zh) 2022-09-11
AU2018200413A1 (en) 2018-02-08
TWI700296B (zh) 2020-08-01
EP2857039A1 (en) 2015-04-08
CA2875205C (en) 2021-07-20
HUE046919T2 (hu) 2020-04-28
KR20200029619A (ko) 2020-03-18
MY172458A (en) 2019-11-26
NZ630536A (en) 2017-03-31
MX361128B (es) 2018-11-28
JP6406678B2 (ja) 2018-10-17
JP6620829B2 (ja) 2019-12-18
TW201410705A (zh) 2014-03-16

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