SG11201501173SA - PI3Kδ INHIBITOR - Google Patents
PI3Kδ INHIBITORInfo
- Publication number
- SG11201501173SA SG11201501173SA SG11201501173SA SG11201501173SA SG11201501173SA SG 11201501173S A SG11201501173S A SG 11201501173SA SG 11201501173S A SG11201501173S A SG 11201501173SA SG 11201501173S A SG11201501173S A SG 11201501173SA SG 11201501173S A SG11201501173S A SG 11201501173SA
- Authority
- SG
- Singapore
- Prior art keywords
- pi3kδ inhibitor
- pi3kδ
- inhibitor
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/32—Nitrogen atom
- C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210279961 | 2012-08-08 | ||
| CN201210529334 | 2012-12-10 | ||
| CN201310130010 | 2013-04-16 | ||
| PCT/CN2013/000934 WO2014023083A1 (en) | 2012-08-08 | 2013-08-08 | PI3Kδ INHIBITOR |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201501173SA true SG11201501173SA (en) | 2015-05-28 |
Family
ID=50067418
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201501173SA SG11201501173SA (en) | 2012-08-08 | 2013-08-08 | PI3Kδ INHIBITOR |
| SG10202003090VA SG10202003090VA (en) | 2012-08-08 | 2013-08-08 | PI3K δ INHIBITOR |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10202003090VA SG10202003090VA (en) | 2012-08-08 | 2013-08-08 | PI3K δ INHIBITOR |
Country Status (3)
| Country | Link |
|---|---|
| CN (1) | CN104768952B (en) |
| SG (2) | SG11201501173SA (en) |
| WO (1) | WO2014023083A1 (en) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6667300B2 (en) | 2000-04-25 | 2003-12-23 | Icos Corporation | Inhibitors of human phosphatidylinositol 3-kinase delta |
| RS55551B1 (en) | 2004-05-13 | 2017-05-31 | Icos Corp | HINAZOLINONS AS HUMAN PHOSPHATIDYLINOSYTOL 3-KINASE DELTA INHIBITORS |
| RU2683793C2 (en) | 2013-09-22 | 2019-04-02 | Калитор Сайенсез, ЛЛС | Substituted aminopyrimidine compounds and methods of use |
| US9708327B2 (en) | 2013-12-20 | 2017-07-18 | Gilead Calistoga Llc | Polymorphic forms of a hydrochloride salt of (S)-2-(1-(9H-purin-6-ylamino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one |
| US9567337B2 (en) | 2013-12-20 | 2017-02-14 | Gilead Calistoga Llc | Process methods for phosphatidylinositol 3-kinase inhibitors |
| MX2016016516A (en) * | 2014-06-13 | 2017-05-01 | Gilead Sciences Inc | Phosphatidylinositol 3-kinase inhibitors. |
| HK1231476A1 (en) * | 2014-06-13 | 2017-12-22 | 吉利德科学公司 | Phosphatidylinositol 3-kinase inhibitors |
| WO2015191745A1 (en) | 2014-06-13 | 2015-12-17 | Gilead Sciences, Inc. | Phosphatidylinositol 3-kinase inhibitors |
| NZ726055A (en) | 2014-06-13 | 2018-04-27 | Gilead Sciences Inc | Quinazolinone derivatives as phosphatidylinositol 3-kinase inhibitors |
| CU24428B1 (en) | 2014-07-04 | 2019-06-04 | Lupin Ltd | QUINOLIZINONE DERIVATIVES AS PI3K INHIBITORS |
| WO2016054491A1 (en) | 2014-10-03 | 2016-04-07 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds and uses thereof |
| US10919914B2 (en) | 2016-06-08 | 2021-02-16 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds and uses thereof |
| KR101932146B1 (en) * | 2016-07-14 | 2018-12-24 | 주식회사 바이오웨이 | Novel Quinazolinone derivatives as PI3K inhibitors, and pharmaceutical composition comprising the same |
| TW201815787A (en) | 2016-09-23 | 2018-05-01 | 美商基利科學股份有限公司 | Phosphatidylinositol 3-kinase inhibitors |
| TW201825465A (en) | 2016-09-23 | 2018-07-16 | 美商基利科學股份有限公司 | Phosphatidylinositol 3-kinase inhibitors |
| TW201813963A (en) | 2016-09-23 | 2018-04-16 | 美商基利科學股份有限公司 | Phosphatidylinositol 3-kinase inhibitors |
| CN108003190B (en) * | 2017-12-27 | 2020-06-12 | 东南大学 | Preparation method of glufosinate-ammonium |
| CA3083040A1 (en) | 2018-01-20 | 2019-07-25 | Sunshine Lake Pharma Co., Ltd. | Substituted aminopyrimidine compounds and methods of use |
| CN110283174B (en) * | 2019-07-31 | 2021-07-23 | 安徽中医药大学 | A class of PI3Kδ inhibitors and their uses |
| CN111440173B (en) * | 2020-03-27 | 2021-05-14 | 山东大学 | A kind of preparation method of PI3K inhibitor |
| CN115304600B (en) * | 2022-09-29 | 2023-01-13 | 北京鑫开元医药科技有限公司 | mTOR inhibitor, preparation method and application |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP20020838A2 (en) * | 2000-04-25 | 2004-12-31 | Icos Corp | Inhibitors of human phosphatidyl-inositol 3-kinase delta |
| RS55551B1 (en) * | 2004-05-13 | 2017-05-31 | Icos Corp | HINAZOLINONS AS HUMAN PHOSPHATIDYLINOSYTOL 3-KINASE DELTA INHIBITORS |
| JP2008501707A (en) * | 2004-06-04 | 2008-01-24 | アイコス、コーポレーション | Methods for treating mast cell disorders |
| CA2716334A1 (en) * | 2007-11-13 | 2009-05-22 | Icos Corporation | Inhibitors of human phosphatidyl-inositol 3-kinase delta |
| JP5869222B2 (en) * | 2008-01-04 | 2016-02-24 | インテリカイン， エルエルシー | Specific chemical entities, compositions and methods |
| CN102838601A (en) * | 2011-06-24 | 2012-12-26 | 山东亨利医药科技有限责任公司 | Selective phosphatidylinositol-3 kinase delta inhibitor |
-
2013
- 2013-08-08 SG SG11201501173SA patent/SG11201501173SA/en unknown
- 2013-08-08 CN CN201380041007.1A patent/CN104768952B/en active Active
- 2013-08-08 WO PCT/CN2013/000934 patent/WO2014023083A1/en not_active Ceased
- 2013-08-08 SG SG10202003090VA patent/SG10202003090VA/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SG10202003090VA (en) | 2020-05-28 |
| WO2014023083A1 (en) | 2014-02-13 |
| CN104768952A (en) | 2015-07-08 |
| CN104768952B (en) | 2016-10-19 |
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