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PL2849746T3 - Kompozycja farmaceutyczna obejmująca (1r,4r)-6'-fluoro-N,N-dimetylo-4-fenylo-4',9'-dihydro-3'H-spiro[cykloheksano-1,1'-pirano[3,4,b]indolo]-4-aminę i meloksykam - Google Patents

Kompozycja farmaceutyczna obejmująca (1r,4r)-6'-fluoro-N,N-dimetylo-4-fenylo-4',9'-dihydro-3'H-spiro[cykloheksano-1,1'-pirano[3,4,b]indolo]-4-aminę i meloksykam

Info

Publication number
PL2849746T3
PL2849746T3 PL13724168T PL13724168T PL2849746T3 PL 2849746 T3 PL2849746 T3 PL 2849746T3 PL 13724168 T PL13724168 T PL 13724168T PL 13724168 T PL13724168 T PL 13724168T PL 2849746 T3 PL2849746 T3 PL 2849746T3
Authority
PL
Poland
Prior art keywords
pyrano
meloxicam
indol
spiro
dihydro
Prior art date
Application number
PL13724168T
Other languages
English (en)
Inventor
Stefanie Frosch
Klaus Linz
Klaus Schiene
Original Assignee
Grünenthal GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Grünenthal GmbH filed Critical Grünenthal GmbH
Publication of PL2849746T3 publication Critical patent/PL2849746T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
PL13724168T 2012-05-18 2013-05-16 Kompozycja farmaceutyczna obejmująca (1r,4r)-6'-fluoro-N,N-dimetylo-4-fenylo-4',9'-dihydro-3'H-spiro[cykloheksano-1,1'-pirano[3,4,b]indolo]-4-aminę i meloksykam PL2849746T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12003896 2012-05-18
EP13724168.3A EP2849746B1 (en) 2012-05-18 2013-05-16 Pharmaceutical composition comprising (1r,4r)-6'-fluoro-n,n-dimethyl-4-phenyl-4',9'-dihydro-3'h-spiro[cyclohexane-1,1'-pyrano [3,4,b]indol]-4-amine and meloxicam
PCT/EP2013/001469 WO2013170970A1 (en) 2012-05-18 2013-05-16 Pharmaceutical composition comprising (1r,4r)-6'-fluoro-n,n-dimethyl-4-phenyl-4',9'-dihydro-3'h-spiro[cyclohexane-1,1'-pyrano [3,4,b]indol]-4-amine and an oxicam

Publications (1)

Publication Number Publication Date
PL2849746T3 true PL2849746T3 (pl) 2018-04-30

Family

ID=48470899

Family Applications (1)

Application Number Title Priority Date Filing Date
PL13724168T PL2849746T3 (pl) 2012-05-18 2013-05-16 Kompozycja farmaceutyczna obejmująca (1r,4r)-6'-fluoro-N,N-dimetylo-4-fenylo-4',9'-dihydro-3'H-spiro[cykloheksano-1,1'-pirano[3,4,b]indolo]-4-aminę i meloksykam

Country Status (22)

Country Link
US (1) US9308196B2 (pl)
EP (1) EP2849746B1 (pl)
JP (1) JP6116677B2 (pl)
CN (2) CN104302288A (pl)
AU (1) AU2013262076B2 (pl)
BR (1) BR112014028569A2 (pl)
CA (1) CA2873863A1 (pl)
CY (1) CY1119824T1 (pl)
DK (1) DK2849746T3 (pl)
EA (1) EA026719B1 (pl)
ES (1) ES2659948T3 (pl)
HR (1) HRP20171843T1 (pl)
HU (1) HUE035122T2 (pl)
IL (1) IL235652B (pl)
LT (1) LT2849746T (pl)
MX (1) MX354685B (pl)
NO (1) NO2849746T3 (pl)
PL (1) PL2849746T3 (pl)
PT (1) PT2849746T (pl)
RS (1) RS56830B1 (pl)
SI (1) SI2849746T1 (pl)
WO (1) WO2013170970A1 (pl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
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EA201791662A1 (ru) 2015-01-23 2017-12-29 Грюненталь Гмбх Цебранопадол для лечения от боли субъектов с нарушенной печеночной и/или нарушенной почечной функцией
BR112018017167A2 (pt) 2016-02-29 2019-01-02 Gruenenthal Gmbh titulação de cebranopadol
GB202405898D0 (en) * 2024-04-26 2024-06-12 Univ Surrey Mycobacterial infections

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US4783337A (en) 1983-05-11 1988-11-08 Alza Corporation Osmotic system comprising plurality of members for dispensing drug
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DE69029732T2 (de) 1989-05-22 1997-05-07 Biochemical Veterinary Research, Mittagong, Neusuedwales Bivalente metallsalze von indomethacin
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CN100560061C (zh) 2008-06-20 2009-11-18 海南锦瑞制药股份有限公司 一种氯诺昔康冻干粉针剂及其制备方法
BRPI0918919A2 (pt) * 2008-09-05 2015-12-01 Gruenenthal Gmbh composição farmaceutica compreendendo 6-dimetilaminometil-1-(3-metoxifenil)-ciclo-hexano-1,3-diol e um nsaid
LT2735338T (lt) * 2008-09-05 2019-04-10 Grünenthal GmbH 3-(3-dimetilamino-1-etil-2-metil-propil)-fenolio ir pregabalino arba gabapentino farmacinis derinys
HUE039328T2 (hu) * 2010-08-04 2018-12-28 Gruenenthal Gmbh 6'-Fluor-(N-metil- vagy N,N-dimetil-)-4-fenil-4',9'-dihidro-3'H-spiro[ciklohexán-1,1'pirano[3,4,B]indol]-4-amin összetételû gyógyszerészeti adagolási forma a neuropátiás fájdalom kezelésére
JP5792301B2 (ja) * 2010-08-04 2015-10-07 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング ６’−フルオロ−（Ｎ−メチル−又はＮ，Ｎ−ジメチル−）−４−フェニル−４’，９’−ジヒドロ−３’Ｈ−スピロ［シクロヘキサン−１，１’−ピラノ［３，４，ｂ］インドール］−４−アミンを含む医薬剤形
CA2804077C (en) * 2010-08-04 2018-09-11 Gruenenthal Gmbh Pharmaceutical dosage form comprising 6'-fluoro-(n-methyl- or n,n-dimethyl-)-4-phenyl-4',9'-dihydro-3'h-spiro[cyclohexane-1,1'-pyrano[3,4,b]indol]-4-amine

Also Published As

Publication number Publication date
US9308196B2 (en) 2016-04-12
DK2849746T3 (en) 2017-12-04
BR112014028569A2 (pt) 2017-06-27
AU2013262076B2 (en) 2017-10-26
SI2849746T1 (en) 2018-02-28
IL235652A0 (en) 2015-01-29
LT2849746T (lt) 2018-02-12
EP2849746A1 (en) 2015-03-25
CN108451956A (zh) 2018-08-28
IL235652B (en) 2018-08-30
WO2013170970A1 (en) 2013-11-21
MX354685B (es) 2018-03-15
HK1204939A1 (en) 2015-12-11
HUE035122T2 (en) 2018-05-02
EA201401265A1 (ru) 2015-05-29
AU2013262076A1 (en) 2015-01-22
EA026719B1 (ru) 2017-05-31
CA2873863A1 (en) 2013-11-21
EP2849746B1 (en) 2017-11-15
ES2659948T3 (es) 2018-03-20
NO2849746T3 (pl) 2018-04-14
US20130310371A1 (en) 2013-11-21
CN104302288A (zh) 2015-01-21
MX2014012862A (es) 2015-01-19
RS56830B1 (sr) 2018-04-30
JP6116677B2 (ja) 2017-04-19
JP2015516450A (ja) 2015-06-11
CY1119824T1 (el) 2018-06-27
PT2849746T (pt) 2018-02-22
HRP20171843T1 (hr) 2018-01-12

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