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LT2849746T - Farmacinė kompozicija, apimanti (1r,4r)-6`-fluor-n,n-dimetil-4-fenil-4`,9`-dihidro-3`h-spiro[cikloheksan-1,1`-pirano [3,4,b]indol]-4-aminą ir meloksikamą - Google Patents

Farmacinė kompozicija, apimanti (1r,4r)-6`-fluor-n,n-dimetil-4-fenil-4`,9`-dihidro-3`h-spiro[cikloheksan-1,1`-pirano [3,4,b]indol]-4-aminą ir meloksikamą

Info

Publication number
LT2849746T
LT2849746T LTEP13724168.3T LT13724168T LT2849746T LT 2849746 T LT2849746 T LT 2849746T LT 13724168 T LT13724168 T LT 13724168T LT 2849746 T LT2849746 T LT 2849746T
Authority
LT
Lithuania
Prior art keywords
pyrano
meloxicam
indol
spiro
dihydro
Prior art date
Application number
LTEP13724168.3T
Other languages
English (en)
Inventor
Stefanie Frosch
Klaus Linz
Klaus Schiene
Original Assignee
Grünenthal GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Grünenthal GmbH filed Critical Grünenthal GmbH
Publication of LT2849746T publication Critical patent/LT2849746T/lt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
LTEP13724168.3T 2012-05-18 2013-05-16 Farmacinė kompozicija, apimanti (1r,4r)-6`-fluor-n,n-dimetil-4-fenil-4`,9`-dihidro-3`h-spiro[cikloheksan-1,1`-pirano [3,4,b]indol]-4-aminą ir meloksikamą LT2849746T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12003896 2012-05-18
PCT/EP2013/001469 WO2013170970A1 (en) 2012-05-18 2013-05-16 Pharmaceutical composition comprising (1r,4r)-6'-fluoro-n,n-dimethyl-4-phenyl-4',9'-dihydro-3'h-spiro[cyclohexane-1,1'-pyrano [3,4,b]indol]-4-amine and an oxicam

Publications (1)

Publication Number Publication Date
LT2849746T true LT2849746T (lt) 2018-02-12

Family

ID=48470899

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP13724168.3T LT2849746T (lt) 2012-05-18 2013-05-16 Farmacinė kompozicija, apimanti (1r,4r)-6`-fluor-n,n-dimetil-4-fenil-4`,9`-dihidro-3`h-spiro[cikloheksan-1,1`-pirano [3,4,b]indol]-4-aminą ir meloksikamą

Country Status (22)

Country Link
US (1) US9308196B2 (lt)
EP (1) EP2849746B1 (lt)
JP (1) JP6116677B2 (lt)
CN (2) CN108451956A (lt)
AU (1) AU2013262076B2 (lt)
BR (1) BR112014028569A2 (lt)
CA (1) CA2873863A1 (lt)
CY (1) CY1119824T1 (lt)
DK (1) DK2849746T3 (lt)
EA (1) EA026719B1 (lt)
ES (1) ES2659948T3 (lt)
HR (1) HRP20171843T1 (lt)
HU (1) HUE035122T2 (lt)
IL (1) IL235652B (lt)
LT (1) LT2849746T (lt)
MX (1) MX354685B (lt)
NO (1) NO2849746T3 (lt)
PL (1) PL2849746T3 (lt)
PT (1) PT2849746T (lt)
RS (1) RS56830B1 (lt)
SI (1) SI2849746T1 (lt)
WO (1) WO2013170970A1 (lt)

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EA201791662A1 (ru) 2015-01-23 2017-12-29 Грюненталь Гмбх Цебранопадол для лечения от боли субъектов с нарушенной печеночной и/или нарушенной почечной функцией
JP7373904B2 (ja) 2016-02-29 2023-11-06 パーク・セラピューティクス・インコーポレイテッド セブラノパドールの滴定
GB202405898D0 (en) * 2024-04-26 2024-06-12 Univ Surrey Mycobacterial infections

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US4612008A (en) 1983-05-11 1986-09-16 Alza Corporation Osmotic device with dual thermodynamic activity
US4765989A (en) 1983-05-11 1988-08-23 Alza Corporation Osmotic device for administering certain drugs
DK0473655T3 (da) 1989-05-22 1997-02-10 Biochemical Veterinary Res Divalente metalsalte af indomethacin
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ATE279920T1 (de) 2000-12-28 2004-11-15 Fresenius Kabi Austria Gmbh Stabile infusionslösung von diclofenac-salzen, deren herstellung und verwendung
PT1374906E (pt) 2002-06-17 2007-07-24 Chiesi Farma Spa Um processo para a preparação de compostos de inclusão de piroxicam: beta-ciclodextrina
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DE10252667A1 (de) 2002-11-11 2004-05-27 Grünenthal GmbH Spirocyclische Cyclohexan-Derivate
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CN102671195B (zh) * 2006-04-28 2016-01-20 格吕伦塔尔有限公司 包含3-(3-二甲基氨基-1-乙基-2-甲基-丙基)-苯酚和nsaid的药物组合物
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SI2600846T1 (sl) * 2010-08-04 2016-02-29 Gruenenthal Gmbh Farmacevtska odmerna oblika, ki obsega 6'-fluoro-(N-metil- ali N,N-dimetil-)-4-fenil-4',9'-dihidro-3'H-spiro(cikloheksan-1,1'-pirano (3,4,b)indol)-4-amin
DK2600851T3 (en) * 2010-08-04 2018-06-25 Gruenenthal Gmbh PHARMACEUTICAL DOSAGE FORM CONTAINING 6'-FLUORO- (N-METHYL OR N, N-DIMETHYL -) - 4-PHENYL-4 ', 9'-DIHYDRO-3'H-SPIRO [CYCLOHEXAN-1,1'-PYRANO [3,4, B] INDOL] -4-AMINE FOR TREATMENT OF NEUROPATHIC PAIN
BR112013004055A2 (pt) * 2010-08-04 2018-04-24 Gruenenthal Gmbh Forma de dosagem farmacêutica compreendendo 6'-fluor-(n-metil- ou n, n-dimetil-)-4-fenil-4',9'-di- hidro-3'h-espiro[cicloexano-1,1'-pirano[3,4-b]indol]-4 -amina.

Also Published As

Publication number Publication date
BR112014028569A2 (pt) 2017-06-27
IL235652A0 (en) 2015-01-29
MX354685B (es) 2018-03-15
HUE035122T2 (en) 2018-05-02
US9308196B2 (en) 2016-04-12
CA2873863A1 (en) 2013-11-21
HK1204939A1 (en) 2015-12-11
RS56830B1 (sr) 2018-04-30
PT2849746T (pt) 2018-02-22
MX2014012862A (es) 2015-01-19
HRP20171843T1 (hr) 2018-01-12
CY1119824T1 (el) 2018-06-27
IL235652B (en) 2018-08-30
EP2849746A1 (en) 2015-03-25
JP2015516450A (ja) 2015-06-11
EA026719B1 (ru) 2017-05-31
PL2849746T3 (pl) 2018-04-30
NO2849746T3 (lt) 2018-04-14
AU2013262076A1 (en) 2015-01-22
JP6116677B2 (ja) 2017-04-19
CN104302288A (zh) 2015-01-21
DK2849746T3 (en) 2017-12-04
CN108451956A (zh) 2018-08-28
AU2013262076B2 (en) 2017-10-26
EA201401265A1 (ru) 2015-05-29
EP2849746B1 (en) 2017-11-15
US20130310371A1 (en) 2013-11-21
ES2659948T3 (es) 2018-03-20
SI2849746T1 (en) 2018-02-28
WO2013170970A1 (en) 2013-11-21

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