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PL2794603T3 - [1,2,4]triazolopirydyny i ich zastosowanie jako inhibitory fosfodiesterazy - Google Patents

[1,2,4]triazolopirydyny i ich zastosowanie jako inhibitory fosfodiesterazy

Info

Publication number
PL2794603T3
PL2794603T3 PL12806051T PL12806051T PL2794603T3 PL 2794603 T3 PL2794603 T3 PL 2794603T3 PL 12806051 T PL12806051 T PL 12806051T PL 12806051 T PL12806051 T PL 12806051T PL 2794603 T3 PL2794603 T3 PL 2794603T3
Authority
PL
Poland
Prior art keywords
triazolopyridines
phospodiesterase inhibitors
phospodiesterase
inhibitors
Prior art date
Application number
PL12806051T
Other languages
English (en)
Inventor
Simon Feldbæk Nielsen
Jens Christian Højland Larsen
Original Assignee
Leo Pharma A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Pharma A/S filed Critical Leo Pharma A/S
Publication of PL2794603T3 publication Critical patent/PL2794603T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/08Antiseborrheics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/14Drugs for dermatological disorders for baldness or alopecia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/16Emollients or protectives, e.g. against radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PL12806051T 2011-12-21 2012-12-19 [1,2,4]triazolopirydyny i ich zastosowanie jako inhibitory fosfodiesterazy PL2794603T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161578677P 2011-12-21 2011-12-21
US201261666430P 2012-06-29 2012-06-29

Publications (1)

Publication Number Publication Date
PL2794603T3 true PL2794603T3 (pl) 2017-08-31

Family

ID=47429831

Family Applications (1)

Application Number Title Priority Date Filing Date
PL12806051T PL2794603T3 (pl) 2011-12-21 2012-12-19 [1,2,4]triazolopirydyny i ich zastosowanie jako inhibitory fosfodiesterazy

Country Status (20)

Country Link
US (2) US8940761B2 (pl)
EP (1) EP2794603B1 (pl)
JP (1) JP6138150B2 (pl)
KR (1) KR20140105598A (pl)
CN (1) CN104011048B (pl)
AU (1) AU2012357106A1 (pl)
BR (1) BR112014014802A2 (pl)
CA (1) CA2858123A1 (pl)
ES (1) ES2583478T3 (pl)
HK (1) HK1200815A1 (pl)
IL (1) IL232712A (pl)
MX (1) MX2014006812A (pl)
PL (1) PL2794603T3 (pl)
PT (1) PT2794603T (pl)
RU (1) RU2630699C2 (pl)
SG (1) SG11201402424PA (pl)
TW (1) TW201331202A (pl)
UA (1) UA111520C2 (pl)
WO (1) WO2013092739A1 (pl)
ZA (1) ZA201403649B (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3070091T3 (pl) * 2010-06-24 2019-09-30 Leo Pharma A/S Pochodne benzodioksolu jako inhibitory fosfodiesterazy
WO2014206903A1 (en) * 2013-06-25 2014-12-31 Leo Pharma A/S METHODS FOR THE PREPARATION OF SUBSTITUTED [1,2,4]TRIAZOLO[1,5-a]PYRIDINES
MX394835B (es) 2017-06-20 2025-03-24 Union Therapeutics As Metodos para la preparacion de compuestos heterociclicos de 1,3-benzodioxol.
ES2935615T3 (es) 2017-12-15 2023-03-08 Union Therapeutics As Azetidina dihidrotienopiridinas sustituidas y su uso como inhibidores de la fosfodiesterasa
ES2968822T3 (es) * 2017-12-15 2024-05-14 Union Therapeutics As Azetidina dihidrotienopirimidinas sustituidas y su uso como inhibidores de la fosfodiesterasa
GB202306662D0 (en) 2023-05-05 2023-06-21 Union Therapeutics As Dosage regimen

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2258775T3 (es) 1995-05-19 2006-09-01 Kyowa Hakko Kogyo Co., Ltd. Compuestos heterociclicos que contienen oxigeno.
WO1998022455A1 (en) 1996-11-19 1998-05-28 Kyowa Hakko Kogyo Co., Ltd. Oxygenic heterocyclic compounds
US6514989B1 (en) * 2001-07-20 2003-02-04 Hoffmann-La Roche Inc. Aromatic and heteroaromatic substituted 1,2,4-triazolo pyridine derivatives
US20080248958A1 (en) * 2007-04-05 2008-10-09 Hollenbach Andrew D System for pulling out regulatory elements in vitro
JP2010523725A (ja) * 2007-04-16 2010-07-15 レオ ファーマ アクティーゼルスカブ 皮膚疾患処置用ホスホジエステラーゼ阻害剤としてのトリアゾロピリジン
EP2200394B1 (en) * 2008-12-19 2012-08-15 Rtx A/S Cell for self-configuring wireless communication network
DK2379548T3 (en) * 2008-12-19 2016-05-17 Leo Pharma As TRIAZOLOPYRIDINER AS phosphodiesterase TO TREAT Skin diseases
US9051290B2 (en) * 2010-04-28 2015-06-09 Leo Pharma A/S Biaryl phosphodiesterase inhibitors

Also Published As

Publication number Publication date
BR112014014802A2 (pt) 2017-06-13
MX2014006812A (es) 2014-10-13
CN104011048B (zh) 2017-03-15
ES2583478T3 (es) 2016-09-21
ZA201403649B (en) 2016-05-25
IL232712A (en) 2016-06-30
SG11201402424PA (en) 2014-09-26
KR20140105598A (ko) 2014-09-01
HK1200815A1 (en) 2015-08-14
IL232712A0 (en) 2014-08-03
RU2630699C2 (ru) 2017-09-12
US9181248B2 (en) 2015-11-10
US8940761B2 (en) 2015-01-27
AU2012357106A1 (en) 2014-06-05
TW201331202A (zh) 2013-08-01
EP2794603B1 (en) 2016-06-15
CN104011048A (zh) 2014-08-27
UA111520C2 (uk) 2016-05-10
WO2013092739A1 (en) 2013-06-27
US20140329853A1 (en) 2014-11-06
JP6138150B2 (ja) 2017-05-31
EP2794603A1 (en) 2014-10-29
CA2858123A1 (en) 2013-06-27
US20150105420A1 (en) 2015-04-16
RU2014129514A (ru) 2016-02-10
JP2015502381A (ja) 2015-01-22
NZ625849A (en) 2016-06-24
PT2794603T (pt) 2016-07-26

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