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PL2303887T3 - Mimetyki helisy alfa i sposoby związane z nimi - Google Patents

Mimetyki helisy alfa i sposoby związane z nimi

Info

Publication number
PL2303887T3
PL2303887T3 PL09758459T PL09758459T PL2303887T3 PL 2303887 T3 PL2303887 T3 PL 2303887T3 PL 09758459 T PL09758459 T PL 09758459T PL 09758459 T PL09758459 T PL 09758459T PL 2303887 T3 PL2303887 T3 PL 2303887T3
Authority
PL
Poland
Prior art keywords
alpha helix
methods relating
helix mimetics
mimetics
relating
Prior art date
Application number
PL09758459T
Other languages
English (en)
Inventor
Takenao Odagami
Yuji Kogami
Hiroyuki Kouji
Original Assignee
Prism Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prism Pharma Co Ltd filed Critical Prism Pharma Co Ltd
Publication of PL2303887T3 publication Critical patent/PL2303887T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/14Drugs for dermatological disorders for baldness or alopecia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Psychology (AREA)
  • Pulmonology (AREA)
  • Vascular Medicine (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL09758459T 2008-06-06 2009-06-05 Mimetyki helisy alfa i sposoby związane z nimi PL2303887T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5960708P 2008-06-06 2008-06-06
EP09758459.3A EP2303887B1 (en) 2008-06-06 2009-06-05 Alpha helix mimetics and methods relating thereto
PCT/JP2009/060718 WO2009148192A1 (en) 2008-06-06 2009-06-05 Alpha helix mimetics and methods relating thereto

Publications (1)

Publication Number Publication Date
PL2303887T3 true PL2303887T3 (pl) 2016-01-29

Family

ID=41058963

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09758459T PL2303887T3 (pl) 2008-06-06 2009-06-05 Mimetyki helisy alfa i sposoby związane z nimi

Country Status (18)

Country Link
US (2) US8455488B2 (pl)
EP (2) EP2650295A1 (pl)
JP (1) JP5530427B2 (pl)
KR (1) KR101671535B1 (pl)
CN (2) CN102046628B (pl)
AU (1) AU2009255042B2 (pl)
BR (1) BRPI0911383B1 (pl)
CA (1) CA2726673C (pl)
DK (1) DK2303887T3 (pl)
ES (1) ES2552239T3 (pl)
HU (1) HUE025831T2 (pl)
IL (1) IL209533A (pl)
MX (1) MX2010013277A (pl)
PL (1) PL2303887T3 (pl)
PT (1) PT2303887E (pl)
RU (1) RU2512538C2 (pl)
SI (1) SI2303887T1 (pl)
WO (1) WO2009148192A1 (pl)

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AU2009255042B2 (en) * 2008-06-06 2014-05-15 Prism Biolab Corporation Alpha helix mimetics and methods relating thereto
CN102186853A (zh) 2008-10-14 2011-09-14 株式会社棱镜生物实验室 治疗癌症α-螺旋模拟物
US9040531B2 (en) 2009-05-07 2015-05-26 Prism BioLab Co., Ltd. Alpha helix mimetics and methods relating thereto
WO2011127164A2 (en) * 2010-04-08 2011-10-13 Fate Therapeutics, Inc. Pharmaceutical compositions to treat fibrosis
CN103517904A (zh) * 2011-02-25 2014-01-15 株式会社棱镜制药 α-螺旋模拟物和与其相关的方法
US9353119B2 (en) 2011-08-09 2016-05-31 Jw Pharmaceutical Corporation Composition for preventing and treating non-small cell lung cancer, containing pyrazino-triazine derivatives
JP6059224B2 (ja) * 2011-08-09 2017-01-11 ジェイダブリュ ファーマセウティカル コーポレーション ピラジノ−トリアジン誘導体を含む非小細胞性肺癌の予防および治療用組成物
EP2768536A4 (en) * 2011-10-19 2015-07-15 Hiroyuki Kouji METHOD OF TREATING TYPE I AND TYPE II DIABETES
US20150284393A1 (en) * 2012-10-19 2015-10-08 Prism Pharma Co., Ltd. Methods for treating eye disorders
WO2014061826A1 (en) * 2012-10-19 2014-04-24 Hiroyuki Kouji Treatment of hyperproliferative and pre-cancerous skin diseases using an inhibitor of cbp/catenin
AU2013332732A1 (en) * 2012-10-19 2015-06-04 Prism Pharma Co., Ltd. Treatment of viral and infectious diseases using an inhibitor of CBP/catenin
JP2015536300A (ja) * 2012-10-19 2015-12-21 株式会社PRISM Pharma Cbp/カテニン阻害剤を用いる強皮症の治療
JP2016502497A (ja) * 2012-10-19 2016-01-28 株式会社PRISM Pharma I型およびii型糖尿病を治療する方法
EP2908820A1 (en) * 2012-10-19 2015-08-26 Prism Pharma Co., Ltd. Treatment of pulmonary fibrosis using an inhibitor of cbp/catenin
CN105163760B (zh) * 2012-12-12 2018-01-26 株式会社棱镜制药 肝纤维化的预防或治疗试剂
CA2928568A1 (en) 2013-07-26 2015-01-29 Update Pharma Inc. Combinatorial methods to improve the therapeutic benefit of bisantrene
CA2923530A1 (en) * 2013-09-11 2015-03-19 Prism Pharma Co., Ltd. Method of producing pyrazino[2,1-c][1,2,4]triazine compound
EP3057590B1 (en) * 2013-10-18 2019-11-27 PRISM BioLab Co., Ltd. Treatment of hepatic fibrosis using an inhibitor of cbp/catenin
US9174998B2 (en) * 2013-12-25 2015-11-03 Eisai R&D Management Co., Ltd. (6S,9aS)-N-benzyl-6-[(4-hydroxyphenyl)methyl]-4,7-dioxo-8-({6-[3-(piperazin-1-yl)azetidin-1-yl]pyridin-2-yl}methyl)-2-(prop-2-en-1-yl)-octahydro-1H-pyrazino[2,1-c][1,2,4]triazine-1-carboxamide compound
MX2016008528A (es) * 2013-12-25 2016-09-13 Prism Pharma Co Ltd Cristales (1) de compuesto de pirazino[2,1-c][1,2,4]triazina.
SG11201605182PA (en) * 2013-12-25 2016-08-30 Prism Pharma Co Ltd CRYSTALS (2) OF PYRAZINO[2,1-c][1,2,4]TRIAZINE COMPOUND
EP3311841B1 (en) * 2015-06-16 2021-07-28 PRISM BioLab Co., Ltd. Anticancer agent
CN107614504B (zh) * 2015-06-23 2019-12-24 卫材R&D管理有限公司 甲酰胺化合物的晶体
JP6785487B2 (ja) * 2015-09-18 2020-11-18 国立大学法人鳥取大学 低分子化合物による癌と線維化の抑制と再生促進の効果
RU2750539C2 (ru) 2017-02-08 2021-06-29 Эйсай Ар Энд Ди Менеджмент Ко., Лтд. Фармацевтическая композиция для лечения опухоли
AU2018269996A1 (en) 2017-05-16 2019-11-21 Eisai R&D Management Co., Ltd. Treatment of hepatocellular carcinoma
KR20220092540A (ko) 2019-10-29 2022-07-01 에자이 알앤드디 매니지먼트 가부시키가이샤 암을 치료하기 위한 pd-1 길항제, vegfr/fgfr/ret 티로신 키나제 억제제 및 cbp/베타-카테닌 억제제의 조합물
WO2021086038A1 (ko) * 2019-10-31 2021-05-06 홀로스메딕 주식회사 신규한 화합물 및 이를 포함하는 암 예방 또는 치료용 약학 조성물
CN116348119A (zh) * 2020-10-10 2023-06-27 株式会社棱镜生物实验室 新的二环化合物
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Also Published As

Publication number Publication date
RU2512538C2 (ru) 2014-04-10
EP2303887B1 (en) 2015-08-05
WO2009148192A1 (en) 2009-12-10
HK1156030A1 (zh) 2012-06-01
IL209533A0 (en) 2011-01-31
JP5530427B2 (ja) 2014-06-25
AU2009255042B2 (en) 2014-05-15
BRPI0911383B1 (pt) 2021-08-31
CN102046628B (zh) 2015-04-15
RU2010154114A (ru) 2012-07-20
MX2010013277A (es) 2011-04-27
US8455488B2 (en) 2013-06-04
PT2303887E (pt) 2015-11-17
KR20110025952A (ko) 2011-03-14
DK2303887T3 (en) 2015-11-02
US9193734B2 (en) 2015-11-24
JP2011522037A (ja) 2011-07-28
HUE025831T2 (en) 2016-04-28
CA2726673C (en) 2016-09-13
CN103450221A (zh) 2013-12-18
IL209533A (en) 2016-11-30
EP2650295A1 (en) 2013-10-16
SI2303887T1 (sl) 2015-12-31
AU2009255042A1 (en) 2009-12-10
ES2552239T3 (es) 2015-11-26
BRPI0911383A2 (pt) 2019-02-26
EP2303887A1 (en) 2011-04-06
US20130267482A1 (en) 2013-10-10
CN102046628A (zh) 2011-05-04
CA2726673A1 (en) 2009-12-10
KR101671535B1 (ko) 2016-11-01
US20110092459A1 (en) 2011-04-21
AU2009255042A2 (en) 2011-01-20

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