PL2303887T3 - Mimetyki helisy alfa i sposoby związane z nimi - Google Patents
Mimetyki helisy alfa i sposoby związane z nimiInfo
- Publication number
- PL2303887T3 PL2303887T3 PL09758459T PL09758459T PL2303887T3 PL 2303887 T3 PL2303887 T3 PL 2303887T3 PL 09758459 T PL09758459 T PL 09758459T PL 09758459 T PL09758459 T PL 09758459T PL 2303887 T3 PL2303887 T3 PL 2303887T3
- Authority
- PL
- Poland
- Prior art keywords
- alpha helix
- methods relating
- helix mimetics
- mimetics
- relating
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Ophthalmology & Optometry (AREA)
- Dermatology (AREA)
- Psychology (AREA)
- Pulmonology (AREA)
- Vascular Medicine (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Gastroenterology & Hepatology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Physical Education & Sports Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5960708P | 2008-06-06 | 2008-06-06 | |
| EP09758459.3A EP2303887B1 (en) | 2008-06-06 | 2009-06-05 | Alpha helix mimetics and methods relating thereto |
| PCT/JP2009/060718 WO2009148192A1 (en) | 2008-06-06 | 2009-06-05 | Alpha helix mimetics and methods relating thereto |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2303887T3 true PL2303887T3 (pl) | 2016-01-29 |
Family
ID=41058963
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL09758459T PL2303887T3 (pl) | 2008-06-06 | 2009-06-05 | Mimetyki helisy alfa i sposoby związane z nimi |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US8455488B2 (pl) |
| EP (2) | EP2650295A1 (pl) |
| JP (1) | JP5530427B2 (pl) |
| KR (1) | KR101671535B1 (pl) |
| CN (2) | CN102046628B (pl) |
| AU (1) | AU2009255042B2 (pl) |
| BR (1) | BRPI0911383B1 (pl) |
| CA (1) | CA2726673C (pl) |
| DK (1) | DK2303887T3 (pl) |
| ES (1) | ES2552239T3 (pl) |
| HU (1) | HUE025831T2 (pl) |
| IL (1) | IL209533A (pl) |
| MX (1) | MX2010013277A (pl) |
| PL (1) | PL2303887T3 (pl) |
| PT (1) | PT2303887E (pl) |
| RU (1) | RU2512538C2 (pl) |
| SI (1) | SI2303887T1 (pl) |
| WO (1) | WO2009148192A1 (pl) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7671054B1 (en) | 2001-10-12 | 2010-03-02 | Choongwae Pharma Corporation | Reverse-turn mimetics and method relating thereto |
| US7576084B2 (en) | 2001-10-12 | 2009-08-18 | Choongwae Pharma Corporation | Reverse-turn mimetics and method relating thereto |
| US7232822B2 (en) | 2001-10-12 | 2007-06-19 | Choongwae Pharma Corporation | Reverse-turn mimetics and method relating thereto |
| AU2009255042B2 (en) * | 2008-06-06 | 2014-05-15 | Prism Biolab Corporation | Alpha helix mimetics and methods relating thereto |
| CN102186853A (zh) | 2008-10-14 | 2011-09-14 | 株式会社棱镜生物实验室 | 治疗癌症α-螺旋模拟物 |
| US9040531B2 (en) | 2009-05-07 | 2015-05-26 | Prism BioLab Co., Ltd. | Alpha helix mimetics and methods relating thereto |
| WO2011127164A2 (en) * | 2010-04-08 | 2011-10-13 | Fate Therapeutics, Inc. | Pharmaceutical compositions to treat fibrosis |
| CN103517904A (zh) * | 2011-02-25 | 2014-01-15 | 株式会社棱镜制药 | α-螺旋模拟物和与其相关的方法 |
| US9353119B2 (en) | 2011-08-09 | 2016-05-31 | Jw Pharmaceutical Corporation | Composition for preventing and treating non-small cell lung cancer, containing pyrazino-triazine derivatives |
| JP6059224B2 (ja) * | 2011-08-09 | 2017-01-11 | ジェイダブリュ ファーマセウティカル コーポレーション | ピラジノ−トリアジン誘導体を含む非小細胞性肺癌の予防および治療用組成物 |
| EP2768536A4 (en) * | 2011-10-19 | 2015-07-15 | Hiroyuki Kouji | METHOD OF TREATING TYPE I AND TYPE II DIABETES |
| US20150284393A1 (en) * | 2012-10-19 | 2015-10-08 | Prism Pharma Co., Ltd. | Methods for treating eye disorders |
| WO2014061826A1 (en) * | 2012-10-19 | 2014-04-24 | Hiroyuki Kouji | Treatment of hyperproliferative and pre-cancerous skin diseases using an inhibitor of cbp/catenin |
| AU2013332732A1 (en) * | 2012-10-19 | 2015-06-04 | Prism Pharma Co., Ltd. | Treatment of viral and infectious diseases using an inhibitor of CBP/catenin |
| JP2015536300A (ja) * | 2012-10-19 | 2015-12-21 | 株式会社PRISM Pharma | Cbp/カテニン阻害剤を用いる強皮症の治療 |
| JP2016502497A (ja) * | 2012-10-19 | 2016-01-28 | 株式会社PRISM Pharma | I型およびii型糖尿病を治療する方法 |
| EP2908820A1 (en) * | 2012-10-19 | 2015-08-26 | Prism Pharma Co., Ltd. | Treatment of pulmonary fibrosis using an inhibitor of cbp/catenin |
| CN105163760B (zh) * | 2012-12-12 | 2018-01-26 | 株式会社棱镜制药 | 肝纤维化的预防或治疗试剂 |
| CA2928568A1 (en) | 2013-07-26 | 2015-01-29 | Update Pharma Inc. | Combinatorial methods to improve the therapeutic benefit of bisantrene |
| CA2923530A1 (en) * | 2013-09-11 | 2015-03-19 | Prism Pharma Co., Ltd. | Method of producing pyrazino[2,1-c][1,2,4]triazine compound |
| EP3057590B1 (en) * | 2013-10-18 | 2019-11-27 | PRISM BioLab Co., Ltd. | Treatment of hepatic fibrosis using an inhibitor of cbp/catenin |
| US9174998B2 (en) * | 2013-12-25 | 2015-11-03 | Eisai R&D Management Co., Ltd. | (6S,9aS)-N-benzyl-6-[(4-hydroxyphenyl)methyl]-4,7-dioxo-8-({6-[3-(piperazin-1-yl)azetidin-1-yl]pyridin-2-yl}methyl)-2-(prop-2-en-1-yl)-octahydro-1H-pyrazino[2,1-c][1,2,4]triazine-1-carboxamide compound |
| MX2016008528A (es) * | 2013-12-25 | 2016-09-13 | Prism Pharma Co Ltd | Cristales (1) de compuesto de pirazino[2,1-c][1,2,4]triazina. |
| SG11201605182PA (en) * | 2013-12-25 | 2016-08-30 | Prism Pharma Co Ltd | CRYSTALS (2) OF PYRAZINO[2,1-c][1,2,4]TRIAZINE COMPOUND |
| EP3311841B1 (en) * | 2015-06-16 | 2021-07-28 | PRISM BioLab Co., Ltd. | Anticancer agent |
| CN107614504B (zh) * | 2015-06-23 | 2019-12-24 | 卫材R&D管理有限公司 | 甲酰胺化合物的晶体 |
| JP6785487B2 (ja) * | 2015-09-18 | 2020-11-18 | 国立大学法人鳥取大学 | 低分子化合物による癌と線維化の抑制と再生促進の効果 |
| RU2750539C2 (ru) | 2017-02-08 | 2021-06-29 | Эйсай Ар Энд Ди Менеджмент Ко., Лтд. | Фармацевтическая композиция для лечения опухоли |
| AU2018269996A1 (en) | 2017-05-16 | 2019-11-21 | Eisai R&D Management Co., Ltd. | Treatment of hepatocellular carcinoma |
| KR20220092540A (ko) | 2019-10-29 | 2022-07-01 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 암을 치료하기 위한 pd-1 길항제, vegfr/fgfr/ret 티로신 키나제 억제제 및 cbp/베타-카테닌 억제제의 조합물 |
| WO2021086038A1 (ko) * | 2019-10-31 | 2021-05-06 | 홀로스메딕 주식회사 | 신규한 화합물 및 이를 포함하는 암 예방 또는 치료용 약학 조성물 |
| CN116348119A (zh) * | 2020-10-10 | 2023-06-27 | 株式会社棱镜生物实验室 | 新的二环化合物 |
| WO2022092294A1 (ja) | 2020-10-30 | 2022-05-05 | 学校法人慶應義塾 | サルコペニア関連疾患等の新規治療および予防 |
| WO2023140369A1 (en) * | 2022-01-18 | 2023-07-27 | Prism BioLab Co., Ltd. | Phosphoric acid derivatives |
| CN119698661A (zh) | 2022-08-16 | 2025-03-25 | 富士胶片株式会社 | 化合物搜索装置、化合物搜索方法及化合物搜索程序 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US544013A (en) * | 1895-08-06 | Hook and eye | ||
| AU1570292A (en) | 1991-02-07 | 1992-09-07 | Board Of Trustees Of The University Of Illinois, The | Conformationally restricted mimetics of beta turns and beta bulges and peptides containing the same |
| AU679460B2 (en) | 1992-08-06 | 1997-07-03 | Molecumetics, Ltd. | Conformationally restricted mimetics of reverse turns and peptides containing the same |
| US6184223B1 (en) | 1995-10-27 | 2001-02-06 | Molecumetics Ltd. | Reverse-turn mimetics and methods relating thereto |
| US6013458A (en) | 1995-10-27 | 2000-01-11 | Molecumetics, Ltd. | Reverse-turn mimetics and methods relating thereto |
| US5929237A (en) | 1995-10-27 | 1999-07-27 | Molecumetics Ltd. | Reverse-turn mimetics and methods relating thereto |
| US6410245B1 (en) | 1998-04-01 | 2002-06-25 | Affymax, Inc. | Compositions and methods for detecting ligand-dependent nuclear receptor and coactivator interactions |
| US6294525B1 (en) | 1999-09-01 | 2001-09-25 | Molecumetics Ltd. | Reverse-turn mimetics and methods relating thereto |
| US20040072831A1 (en) * | 2001-10-12 | 2004-04-15 | Choongwae Pharma Corporation | Reverse-turn mimetics and method relating thereto |
| US7671054B1 (en) * | 2001-10-12 | 2010-03-02 | Choongwae Pharma Corporation | Reverse-turn mimetics and method relating thereto |
| EP1444235B1 (en) * | 2001-10-12 | 2008-06-11 | Choongwae Pharma Corporation | Reverse-turn mimetics and method relating thereto |
| US7232822B2 (en) | 2001-10-12 | 2007-06-19 | Choongwae Pharma Corporation | Reverse-turn mimetics and method relating thereto |
| US7566711B2 (en) * | 2001-10-12 | 2009-07-28 | Choongwae Pharma Corporation | Reverse-turn mimetics and method relating thereto |
| US7576084B2 (en) * | 2001-10-12 | 2009-08-18 | Choongwae Pharma Corporation | Reverse-turn mimetics and method relating thereto |
| IL163562A0 (en) * | 2002-02-19 | 2005-12-18 | Ono Pharmaceutical Co | fused pyridazine derivative compounds and drugs containing the compounds as the active ingredient |
| US6762185B1 (en) * | 2002-03-01 | 2004-07-13 | Choongwae Pharma Corporation | Compounds useful for treatment of cancer, compositions containing the same, and methods of their use |
| AU2003249539A1 (en) | 2002-08-13 | 2004-02-25 | Warner-Lambert Company Llc | Cyclic compounds containing zinc binding groups as matrix metalloproteinase inhibitors |
| WO2004035587A1 (en) | 2002-10-17 | 2004-04-29 | Myriad Genetics, Inc. | Reverse-turn mimetics and composition and methods relating thereto |
| KR20060121842A (ko) * | 2003-08-28 | 2006-11-29 | 주식회사 중외제약 | β-카테닌/TCF에 의해 활성화되는 전사의 조절 |
| WO2006101858A1 (en) * | 2005-03-18 | 2006-09-28 | Institute For Chemical Genomics | Alpha-helix mimetics and methods relating to the treatment of fibrosis |
| US20080009500A1 (en) * | 2005-11-08 | 2008-01-10 | Michael Kahn | Alpha-helix mimetics and methods relating to the treatment of fibrotic disorders |
| ES2570994T3 (es) | 2005-11-08 | 2016-05-23 | Choongwae Pharma Corp | Miméticos de alfa-hélice y método relacionados con el tratamiento de células madre de cáncer |
| CN101495120A (zh) * | 2006-05-30 | 2009-07-29 | 中外制药株式会社 | 用于诱导或抑制干细胞分化的组合物 |
| US7855534B2 (en) * | 2007-08-30 | 2010-12-21 | International Business Machines Corporation | Method for regulating a voltage using a dual loop linear voltage regulator with high frequency noise reduction |
| AU2009255042B2 (en) * | 2008-06-06 | 2014-05-15 | Prism Biolab Corporation | Alpha helix mimetics and methods relating thereto |
-
2009
- 2009-06-05 AU AU2009255042A patent/AU2009255042B2/en not_active Ceased
- 2009-06-05 JP JP2011512295A patent/JP5530427B2/ja active Active
- 2009-06-05 KR KR1020117000138A patent/KR101671535B1/ko active Active
- 2009-06-05 HU HUE09758459A patent/HUE025831T2/en unknown
- 2009-06-05 CN CN200980120602.8A patent/CN102046628B/zh active Active
- 2009-06-05 ES ES09758459.3T patent/ES2552239T3/es active Active
- 2009-06-05 PL PL09758459T patent/PL2303887T3/pl unknown
- 2009-06-05 US US12/996,372 patent/US8455488B2/en active Active
- 2009-06-05 CA CA2726673A patent/CA2726673C/en active Active
- 2009-06-05 WO PCT/JP2009/060718 patent/WO2009148192A1/en not_active Ceased
- 2009-06-05 SI SI200931309T patent/SI2303887T1/sl unknown
- 2009-06-05 CN CN2013102886794A patent/CN103450221A/zh active Pending
- 2009-06-05 EP EP20130172139 patent/EP2650295A1/en not_active Withdrawn
- 2009-06-05 MX MX2010013277A patent/MX2010013277A/es active IP Right Grant
- 2009-06-05 DK DK09758459.3T patent/DK2303887T3/en active
- 2009-06-05 BR BRPI0911383-5A patent/BRPI0911383B1/pt active IP Right Grant
- 2009-06-05 EP EP09758459.3A patent/EP2303887B1/en active Active
- 2009-06-05 RU RU2010154114/04A patent/RU2512538C2/ru active
- 2009-06-05 PT PT97584593T patent/PT2303887E/pt unknown
-
2010
- 2010-11-23 IL IL209533A patent/IL209533A/en active IP Right Grant
-
2013
- 2013-06-03 US US13/908,235 patent/US9193734B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| RU2512538C2 (ru) | 2014-04-10 |
| EP2303887B1 (en) | 2015-08-05 |
| WO2009148192A1 (en) | 2009-12-10 |
| HK1156030A1 (zh) | 2012-06-01 |
| IL209533A0 (en) | 2011-01-31 |
| JP5530427B2 (ja) | 2014-06-25 |
| AU2009255042B2 (en) | 2014-05-15 |
| BRPI0911383B1 (pt) | 2021-08-31 |
| CN102046628B (zh) | 2015-04-15 |
| RU2010154114A (ru) | 2012-07-20 |
| MX2010013277A (es) | 2011-04-27 |
| US8455488B2 (en) | 2013-06-04 |
| PT2303887E (pt) | 2015-11-17 |
| KR20110025952A (ko) | 2011-03-14 |
| DK2303887T3 (en) | 2015-11-02 |
| US9193734B2 (en) | 2015-11-24 |
| JP2011522037A (ja) | 2011-07-28 |
| HUE025831T2 (en) | 2016-04-28 |
| CA2726673C (en) | 2016-09-13 |
| CN103450221A (zh) | 2013-12-18 |
| IL209533A (en) | 2016-11-30 |
| EP2650295A1 (en) | 2013-10-16 |
| SI2303887T1 (sl) | 2015-12-31 |
| AU2009255042A1 (en) | 2009-12-10 |
| ES2552239T3 (es) | 2015-11-26 |
| BRPI0911383A2 (pt) | 2019-02-26 |
| EP2303887A1 (en) | 2011-04-06 |
| US20130267482A1 (en) | 2013-10-10 |
| CN102046628A (zh) | 2011-05-04 |
| CA2726673A1 (en) | 2009-12-10 |
| KR101671535B1 (ko) | 2016-11-01 |
| US20110092459A1 (en) | 2011-04-21 |
| AU2009255042A2 (en) | 2011-01-20 |
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