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PL2350279T3 - Sposoby leczenia chorób oczu - Google Patents

Sposoby leczenia chorób oczu

Info

Publication number
PL2350279T3
PL2350279T3 PL09748890T PL09748890T PL2350279T3 PL 2350279 T3 PL2350279 T3 PL 2350279T3 PL 09748890 T PL09748890 T PL 09748890T PL 09748890 T PL09748890 T PL 09748890T PL 2350279 T3 PL2350279 T3 PL 2350279T3
Authority
PL
Poland
Prior art keywords
methods
eye disorders
treating eye
treating
disorders
Prior art date
Application number
PL09748890T
Other languages
English (en)
Inventor
Elena Feinstein
Evgenia Alpert
Igor Mett
Amir Bar-Ilan
Igor Spivak
Hagar Kalinski
Netanja Slager
Original Assignee
Quark Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Quark Pharmaceuticals Inc filed Critical Quark Pharmaceuticals Inc
Publication of PL2350279T3 publication Critical patent/PL2350279T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/711Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/11Antisense
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/14Type of nucleic acid interfering nucleic acids [NA]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2320/00Applications; Uses
    • C12N2320/30Special therapeutic applications

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL09748890T 2008-10-22 2009-10-22 Sposoby leczenia chorób oczu PL2350279T3 (pl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US19699508P 2008-10-22 2008-10-22
US19893108P 2008-11-11 2008-11-11
IL2009000179 2009-02-15
EP09748890.2A EP2350279B1 (en) 2008-10-22 2009-10-22 Methods for treating eye disorders
PCT/US2009/061570 WO2010048352A2 (en) 2008-10-22 2009-10-22 Methods for treating eye disorders

Publications (1)

Publication Number Publication Date
PL2350279T3 true PL2350279T3 (pl) 2016-05-31

Family

ID=54839547

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09748890T PL2350279T3 (pl) 2008-10-22 2009-10-22 Sposoby leczenia chorób oczu

Country Status (15)

Country Link
US (4) US8765931B2 (pl)
EP (1) EP2350279B1 (pl)
JP (1) JP5592892B2 (pl)
KR (1) KR101672563B1 (pl)
CN (3) CN104857526B (pl)
AU (1) AU2009308380B2 (pl)
CA (2) CA2962219C (pl)
DK (1) DK2350279T3 (pl)
EA (1) EA022418B1 (pl)
ES (1) ES2563984T3 (pl)
IL (1) IL212986A (pl)
NZ (1) NZ591391A (pl)
PL (1) PL2350279T3 (pl)
SI (1) SI2350279T1 (pl)
WO (1) WO2010048352A2 (pl)

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RU2015151857A (ru) 2008-12-02 2019-01-15 Уэйв Лайф Сайенсес Джапан, Инк. Способ синтеза модифицированных по атому фосфора нуклеиновых кислот
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AU2010324658A1 (en) 2009-11-26 2012-05-03 Quark Pharmaceuticals, Inc. siRNA compounds comprising terminal substitutions
WO2012006083A2 (en) * 2010-07-09 2012-01-12 University Of Florida Research Foundation, Inc. Targeted receptor-mediated sirna
US10428019B2 (en) 2010-09-24 2019-10-01 Wave Life Sciences Ltd. Chiral auxiliaries
EP3248982A1 (en) 2011-07-19 2017-11-29 Wave Life Sciences Ltd. Thiosulfonate reagents for the synthesis of functionalized nucleic acids
AU2012332517B9 (en) 2011-11-03 2017-08-10 Quark Pharmaceuticals, Inc. Methods and compositions for neuroprotection
US20140323549A1 (en) * 2011-11-08 2014-10-30 Quark Pharmaceuticals, Inc. Methods and compositions for treating diseases, disorders or injury of the nervous system
CA2858627C (en) 2012-01-04 2020-12-01 Quark Pharmaceuticals, Inc. Double-stranded rna compounds to casp2 and uses thereof
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CA2879023C (en) 2012-07-13 2017-03-28 Wave Life Sciences Japan Asymmetric auxiliary group
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ES2704855T3 (es) 2012-09-12 2019-03-20 Quark Pharmaceuticals Inc Moléculas de oligonucleótido de doble cadena para p53 y métodos de uso de las mismas
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Also Published As

Publication number Publication date
JP5592892B2 (ja) 2014-09-17
CN102994500B (zh) 2015-04-01
CN102449151A (zh) 2012-05-09
EA201170551A1 (ru) 2011-12-30
CA2962219C (en) 2020-08-25
US9701961B2 (en) 2017-07-11
US20110229557A1 (en) 2011-09-22
SI2350279T1 (sl) 2016-04-29
AU2009308380A1 (en) 2010-04-29
JP2012506450A (ja) 2012-03-15
CA2738957A1 (en) 2010-04-29
US9121020B2 (en) 2015-09-01
DK2350279T3 (en) 2016-02-15
CN104857526A (zh) 2015-08-26
WO2010048352A2 (en) 2010-04-29
HK1183693A1 (en) 2014-01-03
KR101672563B1 (ko) 2016-11-03
CA2962219A1 (en) 2010-04-29
US8765931B2 (en) 2014-07-01
IL212986A0 (en) 2011-07-31
US20150361430A1 (en) 2015-12-17
CN102994500A (zh) 2013-03-27
HK1212883A1 (zh) 2016-06-24
WO2010048352A8 (en) 2011-08-11
EP2350279A2 (en) 2011-08-03
EA022418B1 (ru) 2015-12-30
KR20110081826A (ko) 2011-07-14
US20150050328A1 (en) 2015-02-19
ES2563984T3 (es) 2016-03-17
EP2350279B1 (en) 2016-01-27
NZ591391A (en) 2012-10-26
CN104857526B (zh) 2019-03-05
IL212986A (en) 2016-05-31
WO2010048352A3 (en) 2010-06-17
US20170306329A1 (en) 2017-10-26
AU2009308380B2 (en) 2015-05-28

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