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PL2214480T3 - Sposoby leczenia niealkoholowego stłuszczającego zapalenia wątroby (NASH) przy użyciu produktów cysteaminowych - Google Patents

Sposoby leczenia niealkoholowego stłuszczającego zapalenia wątroby (NASH) przy użyciu produktów cysteaminowych

Info

Publication number
PL2214480T3
PL2214480T3 PL08853916T PL08853916T PL2214480T3 PL 2214480 T3 PL2214480 T3 PL 2214480T3 PL 08853916 T PL08853916 T PL 08853916T PL 08853916 T PL08853916 T PL 08853916T PL 2214480 T3 PL2214480 T3 PL 2214480T3
Authority
PL
Poland
Prior art keywords
nash
methods
alcoholic steatohepatitis
treating non
cysteamine products
Prior art date
Application number
PL08853916T
Other languages
English (en)
Inventor
Ranjan Dohil
Jerry Schneider
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40679016&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2214480(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ California filed Critical Univ California
Publication of PL2214480T3 publication Critical patent/PL2214480T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/145Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891Coated capsules; Multilayered drug free capsule shells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
PL08853916T 2007-11-30 2008-11-28 Sposoby leczenia niealkoholowego stłuszczającego zapalenia wątroby (NASH) przy użyciu produktów cysteaminowych PL2214480T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US99151707P 2007-11-30 2007-11-30
US8539708P 2008-07-31 2008-07-31
EP08853916A EP2214480B1 (en) 2007-11-30 2008-11-28 Methods of treating non-alcoholic steatohepatitis (nash) using cysteamine products
PCT/US2008/085064 WO2009070781A1 (en) 2007-11-30 2008-11-28 Methods of treating non-alcoholic steatohepatitis (nash) using cysteamine products

Publications (1)

Publication Number Publication Date
PL2214480T3 true PL2214480T3 (pl) 2013-11-29

Family

ID=40679016

Family Applications (1)

Application Number Title Priority Date Filing Date
PL08853916T PL2214480T3 (pl) 2007-11-30 2008-11-28 Sposoby leczenia niealkoholowego stłuszczającego zapalenia wątroby (NASH) przy użyciu produktów cysteaminowych

Country Status (25)

Country Link
US (5) US7994226B2 (pl)
EP (2) EP2636404B1 (pl)
JP (3) JP5583022B2 (pl)
KR (1) KR20100091219A (pl)
CN (2) CN101932238B (pl)
AR (1) AR069500A1 (pl)
AU (1) AU2008329628B2 (pl)
BR (1) BRPI0819690B8 (pl)
CA (1) CA2706768C (pl)
CL (1) CL2008003582A1 (pl)
CY (1) CY1114126T1 (pl)
DK (1) DK2214480T3 (pl)
ES (1) ES2417179T3 (pl)
HR (1) HRP20130590T1 (pl)
IL (2) IL205909B (pl)
MX (2) MX360827B (pl)
MY (1) MY156316A (pl)
NZ (1) NZ585732A (pl)
PL (1) PL2214480T3 (pl)
PT (1) PT2214480E (pl)
RU (1) RU2498795C2 (pl)
SG (1) SG10201403200RA (pl)
TW (2) TWI478710B (pl)
WO (1) WO2009070781A1 (pl)
ZA (1) ZA201003670B (pl)

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TWI649100B (zh) * 2013-06-17 2019-02-01 地平線罕見醫學製藥有限責任公司 延遲釋放型半胱胺珠粒調配物,以及其製備及使用方法
US9682123B2 (en) 2013-12-20 2017-06-20 The Trustees Of Columbia University In The City Of New York Methods of treating metabolic disease
CN113967215A (zh) * 2014-04-18 2022-01-25 Lg 化学株式会社 用于预防或治疗脂肪肝疾病的组合物
BR112017018882A2 (pt) * 2015-03-03 2018-04-17 Kohjin Life Sciences Co Ltd composição para aperfeiçoamento ou prevenção de uma doença de fígado gorduroso não alcoólico
RU2766579C2 (ru) 2015-07-02 2022-03-15 ХОРАЙЗОН ОРФАН ЭлЭлСи Цистеаминдиоксигеназа-резистентные аналоги цистеамина и их применение
RU2595815C1 (ru) * 2015-07-13 2016-08-27 федеральное государственное бюджетное образовательное учреждение высшего образования "Северо-Западный государственный медицинский университет им. И.И. Мечникова" Министерства здравоохранения Российской Федерации Способ лечения больных неалкогольным стеатогепатитом на фоне метаболического синдрома
WO2017087532A1 (en) * 2015-11-16 2017-05-26 The Regents Of The University Of California Methods of treating non-alcoholic steatohepatitis (nash) using cysteamine compounds
US10143665B2 (en) 2015-11-17 2018-12-04 Horizon Orphan Llc Methods for storing cysteamine formulations and related methods of treatment
KR102414503B1 (ko) 2016-03-17 2022-06-29 티오제네시스 테라퓨틱스, 인크. 시스테아민의 조절 방출을 위한 조성물 및 시스테아민 민감성 장애의 전신 치료
ITUA20161799A1 (it) * 2016-03-18 2017-09-18 Recordati Ind Chimica E Farmaceutica S P A Composizione farmaceutica a rilascio prolungato comprendente cisteamina o un suo sale
JP7270979B2 (ja) * 2017-06-08 2023-05-11 エヌ-ジーン リサーチ ラボラトリーズ,アイエヌシー. Nash治療方法及びnash誘発性hcc予防方法
WO2019046659A1 (en) * 2017-08-30 2019-03-07 First Fruits Business Ministry, Llc COMPOSITION AND METHOD FOR INCREASING SERIAL ADIPONECTIN AND REDUCING THE LIPID RESERVES OF THE ORGANISM
US11612576B2 (en) 2017-09-20 2023-03-28 Thiogenesis Therapeutics, Inc. Methods for the treatment of cysteamine sensitive disorders
KR102177304B1 (ko) * 2018-07-23 2020-11-10 제이투에이치바이오텍 (주) 비알콜성 지방간염의 예방 또는 치료용 약학 조성물
CN111544426A (zh) * 2019-02-12 2020-08-18 复旦大学 炔丙基半胱氨酸及其在制备新靶点药物中的用途
WO2020198529A1 (en) * 2019-03-26 2020-10-01 The Regents Of The University Ofcalifornia Substituted amino-thiol and amino-disulfide compounds, and uses thereof
CA3143834A1 (en) * 2019-07-19 2021-01-28 Xiyan LI Compositions, methods, kits and systems for cancer treatment and metabolic intervention therapy and other uses
CN111505099B (zh) * 2020-04-21 2023-07-04 上海市普陀区中心医院 Nash的诊断标志物及其应用
CN116546981A (zh) * 2020-12-18 2023-08-04 雀巢产品有限公司 使用至少一种甘氨酸或其衍生物和/或至少一种n-乙酰半胱氨酸或其衍生物以及至少一种百里酚和/或香芹酚的组合物和方法
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Also Published As

Publication number Publication date
DK2214480T3 (da) 2013-07-08
AU2008329628B2 (en) 2014-06-26
TWI478710B (zh) 2015-04-01
KR20100091219A (ko) 2010-08-18
TW201513855A (zh) 2015-04-16
TW200927093A (en) 2009-07-01
US9149448B2 (en) 2015-10-06
IL254586A0 (en) 2017-11-30
US10307386B2 (en) 2019-06-04
IL205909A0 (en) 2010-11-30
US20160143865A1 (en) 2016-05-26
SG10201403200RA (en) 2014-10-30
EP2636404A3 (en) 2013-10-16
EP2636404A2 (en) 2013-09-11
EP2214480A1 (en) 2010-08-11
EP2214480B1 (en) 2013-03-27
CY1114126T1 (el) 2016-07-27
PT2214480E (pt) 2013-07-23
JP2014237670A (ja) 2014-12-18
US8263662B2 (en) 2012-09-11
RU2010126631A (ru) 2012-01-10
CA2706768C (en) 2016-06-28
US9511038B2 (en) 2016-12-06
CN104825430A (zh) 2015-08-12
CN104825430B (zh) 2018-05-04
CL2008003582A1 (es) 2009-04-03
US20130183351A1 (en) 2013-07-18
MX2010005921A (es) 2010-06-11
ZA201003670B (en) 2011-08-31
US20170304233A1 (en) 2017-10-26
JP2011505375A (ja) 2011-02-24
US7994226B2 (en) 2011-08-09
JP2017165735A (ja) 2017-09-21
CN101932238A (zh) 2010-12-29
BRPI0819690B8 (pt) 2021-05-25
AU2008329628A1 (en) 2009-06-04
MX360827B (es) 2018-11-16
JP5583022B2 (ja) 2014-09-03
MY156316A (en) 2016-02-11
CA2706768A1 (en) 2009-06-04
CN101932238B (zh) 2015-04-08
HRP20130590T1 (en) 2013-08-31
ES2417179T3 (es) 2013-08-06
BRPI0819690B1 (pt) 2019-07-30
TWI535435B (zh) 2016-06-01
HK1141945A1 (en) 2010-11-26
WO2009070781A1 (en) 2009-06-04
NZ585732A (en) 2012-02-24
RU2498795C2 (ru) 2013-11-20
JP6121951B2 (ja) 2017-04-26
AR069500A1 (es) 2010-01-27
IL205909B (en) 2018-05-31
EP2636404B1 (en) 2019-03-20
US20100303870A1 (en) 2010-12-02
EP2214480A4 (en) 2010-09-29
BRPI0819690A2 (pt) 2014-10-07
US20120015005A1 (en) 2012-01-19

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