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PL2183201T3 - Sposób rozdziału zopiklonu i związki pośrednie - Google Patents

Sposób rozdziału zopiklonu i związki pośrednie

Info

Publication number
PL2183201T3
PL2183201T3 PL08786735T PL08786735T PL2183201T3 PL 2183201 T3 PL2183201 T3 PL 2183201T3 PL 08786735 T PL08786735 T PL 08786735T PL 08786735 T PL08786735 T PL 08786735T PL 2183201 T3 PL2183201 T3 PL 2183201T3
Authority
PL
Poland
Prior art keywords
resolution
formula
zopiclone
intermediate compounds
enantiomers
Prior art date
Application number
PL08786735T
Other languages
English (en)
Inventor
Bleda David Fernández
Tous Jordi Lluís
Original Assignee
Esteve Quim S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Esteve Quim S A filed Critical Esteve Quim S A
Publication of PL2183201T3 publication Critical patent/PL2183201T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B57/00—Separation of optically-active compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
PL08786735T 2007-08-02 2008-08-01 Sposób rozdziału zopiklonu i związki pośrednie PL2183201T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07380226A EP2020403A1 (en) 2007-08-02 2007-08-02 Process for the resolution of zopiclone and intermediate compounds
EP08786735A EP2183201B1 (en) 2007-08-02 2008-08-01 Process for the resolution of zopiclone and intermediate compounds
PCT/EP2008/060115 WO2009016251A1 (en) 2007-08-02 2008-08-01 Process for the resolution of zopiclone and intermediate compounds

Publications (1)

Publication Number Publication Date
PL2183201T3 true PL2183201T3 (pl) 2012-09-28

Family

ID=38871700

Family Applications (1)

Application Number Title Priority Date Filing Date
PL08786735T PL2183201T3 (pl) 2007-08-02 2008-08-01 Sposób rozdziału zopiklonu i związki pośrednie

Country Status (17)

Country Link
US (2) US7772396B2 (pl)
EP (2) EP2020403A1 (pl)
JP (1) JP2010535177A (pl)
KR (1) KR20100044241A (pl)
CN (1) CN101772475B (pl)
AT (1) ATE551312T1 (pl)
AU (1) AU2008281717A1 (pl)
CA (1) CA2695254A1 (pl)
ES (1) ES2385120T3 (pl)
HR (1) HRP20120306T1 (pl)
IL (1) IL203557A (pl)
MX (1) MX2010001229A (pl)
NZ (1) NZ583097A (pl)
PL (1) PL2183201T3 (pl)
RU (1) RU2010107453A (pl)
SI (1) SI2183201T1 (pl)
WO (1) WO2009016251A1 (pl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7476737B2 (en) * 2005-09-05 2009-01-13 Dr. Reddy's Laboratories Limited Eszopiclone process
CN102731494A (zh) * 2005-12-19 2012-10-17 西科尔公司 噻托溴铵的新形式及其制备方法
CN101607961B (zh) * 2008-06-18 2011-08-10 天津天士力集团有限公司 一种右佐匹克隆结晶及其组合物
EP2345654A1 (en) * 2010-01-05 2011-07-20 LEK Pharmaceuticals d.d. Eszopiclone particles and a process for their preparation
CN103193779B (zh) * 2012-01-05 2016-04-20 成都弘达药业有限公司 一种右佐匹克隆的制备方法
KR20160110517A (ko) 2014-02-06 2016-09-21 우베 고산 가부시키가이샤 인돌린 화합물의 제조 방법
DE102020205560B4 (de) 2020-04-30 2022-05-25 Zettl Interieur Gmbh Flexible atemschutzmaske und deren verwendung
CN113214267B (zh) * 2021-05-08 2022-06-28 上海中西三维药业有限公司 一种制备纯净且光学富集的右佐匹克隆精制方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
OA04285A (fr) 1972-01-07 1979-12-31 Rhone Poulenc Sa Nouveaux dérivés de la pyrrolo (3,4-b) pyrazine et leur préparation.
FR2671800B1 (fr) 1991-01-17 1993-03-12 Rhone Poulenc Rorer Sa Derive de la 5h-pyrrolo[3,4-b]pyrazine optiquement actif, sa preparation et les compositions pharmaceutiques qui le contiennent.
ES2203319B1 (es) 2002-04-03 2005-03-01 Universidad De Oviedo Nuevos carbonatos opticamente activos como intermedios en la sintesis de (+)-zopiclona.
EP2343073A3 (en) 2003-12-11 2011-10-12 Sepracor Inc. Combination of a sedative and a neurotransmitter modulator, and methods for improving sleep quality and treating depression
EP1742624B1 (en) 2004-02-18 2010-01-06 Sepracor, Inc. Dopamine-agonist combination therapy with sedatives for improving sleep quality
CA2677465A1 (en) 2004-04-05 2005-10-20 Sepracor Inc. Methods of treatment using eszopiclone
EP1919912A1 (en) 2005-06-21 2008-05-14 Merck Generics (UK) Limited Process for enantiomeric separation of zopiclone
US7476737B2 (en) 2005-09-05 2009-01-13 Dr. Reddy's Laboratories Limited Eszopiclone process
US7863273B2 (en) 2006-01-17 2011-01-04 Glenmark Generics Ltd. Process for the preparation of an optically active 5H-pyrrolo [3,4-B] pyrazine derivative
AR059296A1 (es) 2006-02-03 2008-03-26 Synthon Bv Compuesto de l-tartrato de s-zopiclona y proceso para resolver los enantiomeros de zopiclona.
US20080027223A1 (en) 2006-03-23 2008-01-31 Teva Pharmaceutical Industries Ltd. Polymorphs of eszopiclone malate
EP2007768A2 (en) 2006-04-20 2008-12-31 Teva Pharmaceutical Industries Ltd Methods for preparing eszopiclone crystalline form a, substantially pure eszopiclone and optically enriched eszopiclone

Also Published As

Publication number Publication date
WO2009016251A1 (en) 2009-02-05
ES2385120T3 (es) 2012-07-18
JP2010535177A (ja) 2010-11-18
HRP20120306T1 (hr) 2012-04-30
KR20100044241A (ko) 2010-04-29
US20090036681A1 (en) 2009-02-05
US20100274018A1 (en) 2010-10-28
AU2008281717A1 (en) 2009-02-05
EP2020403A1 (en) 2009-02-04
SI2183201T1 (sl) 2012-05-31
CN101772475A (zh) 2010-07-07
EP2183201A1 (en) 2010-05-12
CA2695254A1 (en) 2009-02-05
RU2010107453A (ru) 2011-09-10
US7968712B2 (en) 2011-06-28
NZ583097A (en) 2011-03-31
IL203557A (en) 2014-11-30
ATE551312T1 (de) 2012-04-15
MX2010001229A (es) 2010-03-04
CN101772475B (zh) 2013-11-06
EP2183201B1 (en) 2012-03-28
US7772396B2 (en) 2010-08-10

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