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PL2007391T3 - Kombinacja zawierająca A) pirymidyloaminobenzamid i B) inhibitor kinazy THR315LLE - Google Patents

Kombinacja zawierająca A) pirymidyloaminobenzamid i B) inhibitor kinazy THR315LLE

Info

Publication number
PL2007391T3
PL2007391T3 PL07727881T PL07727881T PL2007391T3 PL 2007391 T3 PL2007391 T3 PL 2007391T3 PL 07727881 T PL07727881 T PL 07727881T PL 07727881 T PL07727881 T PL 07727881T PL 2007391 T3 PL2007391 T3 PL 2007391T3
Authority
PL
Poland
Prior art keywords
thr315lle
combination
kinase inhibitor
pyrimidylaminobenzamide compound
pyrimidylaminobenzamide
Prior art date
Application number
PL07727881T
Other languages
English (en)
Inventor
Paul W Manley
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PL2007391T3 publication Critical patent/PL2007391T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965Non-condensed pyrazines
    • A61K31/497Non-condensed pyrazines containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL07727881T 2006-04-07 2007-04-05 Kombinacja zawierająca A) pirymidyloaminobenzamid i B) inhibitor kinazy THR315LLE PL2007391T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US79043806P 2006-04-07 2006-04-07
US79115006P 2006-04-11 2006-04-11
EP07727881.0A EP2007391B8 (en) 2006-04-07 2007-04-05 Combination comprising a) a pyrimidylaminobenzamide compound, and b) a thr315ile kinase inhibitor
PCT/EP2007/053413 WO2007116029A2 (en) 2006-04-07 2007-04-05 Combination comprising a) a pyrimidylaminobenzamide compound, and b) a thr315lle kinase inhibitor

Publications (1)

Publication Number Publication Date
PL2007391T3 true PL2007391T3 (pl) 2013-05-31

Family

ID=38229305

Family Applications (1)

Application Number Title Priority Date Filing Date
PL07727881T PL2007391T3 (pl) 2006-04-07 2007-04-05 Kombinacja zawierająca A) pirymidyloaminobenzamid i B) inhibitor kinazy THR315LLE

Country Status (13)

Country Link
US (1) US20090286803A1 (pl)
EP (2) EP2574340A3 (pl)
JP (2) JP2009532440A (pl)
KR (1) KR20090023561A (pl)
AU (1) AU2007235900A1 (pl)
BR (1) BRPI0710496A2 (pl)
CA (1) CA2647803C (pl)
ES (1) ES2400375T3 (pl)
MX (1) MX2008012971A (pl)
PL (1) PL2007391T3 (pl)
PT (1) PT2007391E (pl)
RU (2) RU2481840C2 (pl)
WO (1) WO2007116029A2 (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20100016584A (ko) * 2007-04-17 2010-02-12 노파르티스 아게 암 치료제로서의 나프탈렌 카르복실산 아미드의 에테르
JO3265B1 (ar) 2008-12-09 2018-09-16 Novartis Ag مثبطات بيريديلوكسى اندولات vegf-r2 واستخدامها لعلاج المرض
KR20120115237A (ko) * 2009-10-30 2012-10-17 어리어드 파마슈티칼스, 인코포레이티드 암 치료 방법 및 조성물
EP2526084A1 (en) * 2010-01-20 2012-11-28 Pronova BioPharma Norge AS Salicylate fatty acid derivatives
CN109846879B (zh) * 2017-03-01 2021-06-29 浙江大学 亚胺结构类型雄激素受体拮抗剂及其应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7625913B2 (en) 2000-12-21 2009-12-01 Vertex Pharmaceuticals Incorporated Pyrazole compounds useful as protein kinase inhibitors
PT2177223E (pt) * 2001-09-05 2012-05-23 Chemgenex Pharmaceuticals Ltd Tratamento da leucemia mielóide crónica, resistente ou intolerante ao sti571, envolvendo a homoharringtonina isoladamente ou em combinação com outros agentes
US7307071B2 (en) * 2001-12-04 2007-12-11 Onyx Pharmaceuticals, Inc RAF-MEK-ERK pathway inhibitors to treat cancer
TW200406374A (en) 2002-05-29 2004-05-01 Novartis Ag Diaryl urea derivatives useful for the treatment of protein kinase dependent diseases
FR2841116B1 (fr) 2002-06-19 2004-11-26 Seb Sa Cafetiere du type expresso a reservoir d'eau amovible
GB0215676D0 (en) * 2002-07-05 2002-08-14 Novartis Ag Organic compounds
WO2004026234A2 (en) * 2002-09-19 2004-04-01 University Of South Florida Method of treating leukemia with a combination of suberoylanilide hydromaxic acid and imatinib mesylate
DE10330916A1 (de) 2003-07-04 2005-02-03 Pilz Gmbh & Co. Kg Vorrichtung und Verfahren zum automatisierten Steuern eines Betriebsablaufs bei einer technischen Anlage
US7338957B2 (en) 2003-08-28 2008-03-04 Irm Llc Compounds and compositions as protein kinase inhibitors
WO2005123719A1 (en) * 2004-06-10 2005-12-29 Irm Llc Compounds and compositions as protein kinase inhibitors
US20080038267A1 (en) * 2004-07-02 2008-02-14 Neutec Pharma Limited Treatment Of Cancer
PE20060664A1 (es) 2004-09-15 2006-08-04 Novartis Ag Amidas biciclicas como inhibidores de cinasa
GB0421525D0 (en) * 2004-09-28 2004-10-27 Novartis Ag Inhibitors of protein kineses
US20070161645A1 (en) * 2005-11-02 2007-07-12 Targegen, Inc. Thiazole inhibitors targeting resistant kinase mutations

Also Published As

Publication number Publication date
AU2007235900A1 (en) 2007-10-18
EP2007391A2 (en) 2008-12-31
ES2400375T8 (es) 2013-09-10
MX2008012971A (es) 2008-10-15
ES2400375T3 (es) 2013-04-09
JP2013224304A (ja) 2013-10-31
US20090286803A1 (en) 2009-11-19
EP2574340A2 (en) 2013-04-03
CA2647803C (en) 2014-05-27
CA2647803A1 (en) 2007-10-18
WO2007116029A2 (en) 2007-10-18
RU2008143704A (ru) 2010-05-20
PT2007391E (pt) 2013-03-11
EP2007391B1 (en) 2012-12-19
EP2007391B8 (en) 2013-05-29
KR20090023561A (ko) 2009-03-05
RU2013103746A (ru) 2014-08-10
WO2007116029A3 (en) 2008-12-11
EP2574340A3 (en) 2013-04-17
RU2481840C2 (ru) 2013-05-20
JP2009532440A (ja) 2009-09-10
BRPI0710496A2 (pt) 2011-08-16

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