PL2054405T3 - Nowe pochodne biarylobenzimidazolu i zawierająca je kompozycja farmaceutyczna - Google Patents
Nowe pochodne biarylobenzimidazolu i zawierająca je kompozycja farmaceutycznaInfo
- Publication number
- PL2054405T3 PL2054405T3 PL07768695T PL07768695T PL2054405T3 PL 2054405 T3 PL2054405 T3 PL 2054405T3 PL 07768695 T PL07768695 T PL 07768695T PL 07768695 T PL07768695 T PL 07768695T PL 2054405 T3 PL2054405 T3 PL 2054405T3
- Authority
- PL
- Poland
- Prior art keywords
- same
- pharmaceutical composition
- benzoimidazole derivatives
- novel biaryl
- biaryl benzoimidazole
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20060065115 | 2006-07-11 | ||
| EP07768695.4A EP2054405B1 (en) | 2006-07-11 | 2007-07-11 | Novel biaryl benzoimidazole derivatives and pharmaceutical composition comprising the same |
| PCT/KR2007/003362 WO2008007900A1 (en) | 2006-07-11 | 2007-07-11 | Novel biaryl benzoimidazole derivatives and pharmaceutical composition comprising the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2054405T3 true PL2054405T3 (pl) | 2014-03-31 |
Family
ID=38923421
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL07768695T PL2054405T3 (pl) | 2006-07-11 | 2007-07-11 | Nowe pochodne biarylobenzimidazolu i zawierająca je kompozycja farmaceutyczna |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US8436022B2 (pl) |
| EP (1) | EP2054405B1 (pl) |
| JP (1) | JP5054770B2 (pl) |
| CN (1) | CN101490037B (pl) |
| AU (1) | AU2007273333B2 (pl) |
| CA (1) | CA2656810C (pl) |
| ES (1) | ES2438240T3 (pl) |
| MY (1) | MY157033A (pl) |
| NZ (1) | NZ574697A (pl) |
| PL (1) | PL2054405T3 (pl) |
| PT (1) | PT2054405E (pl) |
| WO (1) | WO2008007900A1 (pl) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102015606B (zh) | 2007-06-08 | 2015-02-04 | 满康德股份有限公司 | IRE-1α抑制剂 |
| MY158994A (en) | 2008-02-04 | 2016-11-30 | Mercury Therapeutics Inc | Ampk modulators |
| KR101252334B1 (ko) | 2008-04-18 | 2013-04-08 | 주식회사 대웅제약 | 신규 벤조옥사진 벤즈이미다졸 유도체, 이를 포함하는 약학 조성물 및 이의 용도 |
| ES2531109T3 (es) | 2009-12-30 | 2015-03-10 | Arqule Inc | Compuestos de imidazopiridinil-aminopiridina |
| AU2011308256B2 (en) * | 2010-09-28 | 2015-08-20 | Daewoong Pharmaceutical Co., Ltd. | Novel method of preparing benzoimidazole derivatives |
| KR101293384B1 (ko) * | 2010-10-13 | 2013-08-05 | 주식회사 대웅제약 | 신규 피리딜 벤조옥사진 유도체, 이를 포함하는 약학 조성물 및 이의 용도 |
| JP5789888B2 (ja) * | 2010-11-01 | 2015-10-07 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ロイコトリエン生成のベンゾイミダゾールインヒビター |
| KR20190015600A (ko) | 2011-06-24 | 2019-02-13 | 아르퀼 인코포레이티드 | 치환된 이미다조피리디닐-아미노피리딘 화합물 |
| WO2012177852A1 (en) | 2011-06-24 | 2012-12-27 | Arqule, Inc | Substituted imidazopyridinyl compounds |
| WO2014151630A2 (en) | 2013-03-15 | 2014-09-25 | Irm Llc | Compounds and compositions for the treatment of parasitic diseases |
| WO2014151729A1 (en) | 2013-03-15 | 2014-09-25 | Irm Llc | Compounds and compositions for the treatment of parasitic diseases |
| US9296754B2 (en) | 2013-03-15 | 2016-03-29 | Novartis Ag | Compounds and compositions for the treatment of parasitic diseases |
| TWI674263B (zh) | 2013-12-19 | 2019-10-11 | 瑞士商諾華公司 | 用於治療寄生蟲疾病之化合物及組合物 |
| WO2016004513A1 (en) * | 2014-07-11 | 2016-01-14 | Simon Fraser University | Anti-bacterial pyruvate kinase modulator compounds, compositions, uses and methods |
| KR20200003045A (ko) * | 2017-05-02 | 2020-01-08 | 바이엘 악티엔게젤샤프트 | 해충 방제제로서의 2-(헤트)아릴-치환된 축합된 비시클릭 헤테로시클릭 유도체 |
| WO2018202494A1 (de) * | 2017-05-02 | 2018-11-08 | Bayer Aktiengesellschaft | 2-(het)aryl-substituierte kondensierte heterocyclen-derivate als schädlingsbekämpfungsmittel |
| US11555035B2 (en) | 2017-12-22 | 2023-01-17 | Sumitomo Chemical Company, Limited | Heterocyclic compound and harmful arthropod-controlling agent containing same |
| CN112074505B (zh) | 2018-03-08 | 2024-04-05 | 因赛特公司 | 作为PI3K-γ抑制剂的氨基吡嗪二醇化合物 |
| ES2992256T3 (es) | 2018-05-08 | 2024-12-11 | Nippon Shinyaku Co Ltd | Compuestos de azabencimidazol y producto farmacéutico |
| US11046658B2 (en) | 2018-07-02 | 2021-06-29 | Incyte Corporation | Aminopyrazine derivatives as PI3K-γ inhibitors |
| EP4059503A4 (en) * | 2019-11-13 | 2023-11-15 | Nippon Shinyaku Co., Ltd. | THERAPEUTIC AND PROPHYLACTIC FOR FUNCTIONAL GASTROINTESTINAL DISORDERS AND XEROSTOMIA |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1264381A (zh) * | 1997-08-05 | 2000-08-23 | 辉瑞产品公司 | 4-氨基吡咯并(3,2-d)嘧啶作为神经肽Y受体拮抗药 |
| JP2002514635A (ja) | 1998-05-12 | 2002-05-21 | アメリカン・ホーム・プロダクツ・コーポレイション | インスリン耐性および高血糖の処置に有用なビフェニルオキソ−酢酸 |
| JP2001039034A (ja) * | 1999-08-03 | 2001-02-13 | Mitsui Chemicals Inc | 光記録媒体 |
| JP2003515560A (ja) | 1999-12-06 | 2003-05-07 | スミスクライン・ビーチャム・コーポレイション | トロンボポイエチン模倣物 |
| GB0017256D0 (en) * | 2000-07-13 | 2000-08-30 | Merck Sharp & Dohme | Therapeutic agents |
| US7271261B2 (en) | 2001-10-19 | 2007-09-18 | Ortho-Mcneil Pharmaceutical, Inc. | Substituted benzimidazoles and imidazo-[4,5]-pyridines |
| US6972281B2 (en) * | 2002-02-07 | 2005-12-06 | University Of Ottawa | Histogranin-like peptides and non-peptides, processes for their preparation and uses thereof |
| CA2484209C (en) | 2002-05-03 | 2013-06-11 | Exelixis, Inc. | Protein kinase modulators and methods of use |
| CN1671672A (zh) * | 2002-07-31 | 2005-09-21 | 欧洲凯尔特股份有限公司 | 芳基取代的苯并咪唑类及其作为钠通道阻滞剂的用途 |
| JP2006516626A (ja) | 2003-01-28 | 2006-07-06 | スミスクライン ビーチャム コーポレーション | 化学的化合物 |
| US7777051B2 (en) | 2003-05-13 | 2010-08-17 | Icagen, Inc. | Asymmetric benzimidazoles and related compounds as potassium channel modulators |
| CN1898214A (zh) | 2003-10-24 | 2007-01-17 | 北卡罗来纳大学查珀尔希尔分校 | 作为抗原虫药的双阳离子三芳基类似物 |
| WO2006000020A1 (en) | 2004-06-29 | 2006-01-05 | European Nickel Plc | Improved leaching of base metals |
| AU2006209117B2 (en) | 2005-01-28 | 2009-12-10 | Daewoong Pharmaceutical Co., Ltd. | Novel benzoimidazole derivatives and pharmaceutical composition comprising the same |
| BRPI0611707A2 (pt) | 2005-06-29 | 2012-04-24 | Compumedics Ltd | conjunto de sensor com ponte condutiva |
| WO2007034277A1 (en) | 2005-09-19 | 2007-03-29 | Pfizer Products Inc. | Aryl substituted imidazo [4,5-c] pyridine compounds as c3a receptor antagonists |
| EP1966157B1 (en) * | 2005-11-15 | 2010-03-24 | Abbott Laboratories | Substituted 1h-benzimidazole-4-carboxamides are potent parp inhibitors |
-
2007
- 2007-07-11 CA CA2656810A patent/CA2656810C/en active Active
- 2007-07-11 EP EP07768695.4A patent/EP2054405B1/en active Active
- 2007-07-11 AU AU2007273333A patent/AU2007273333B2/en not_active Ceased
- 2007-07-11 WO PCT/KR2007/003362 patent/WO2008007900A1/en not_active Ceased
- 2007-07-11 JP JP2009519377A patent/JP5054770B2/ja active Active
- 2007-07-11 PL PL07768695T patent/PL2054405T3/pl unknown
- 2007-07-11 US US12/373,193 patent/US8436022B2/en active Active
- 2007-07-11 MY MYPI20090092A patent/MY157033A/en unknown
- 2007-07-11 PT PT77686954T patent/PT2054405E/pt unknown
- 2007-07-11 NZ NZ574697A patent/NZ574697A/en not_active IP Right Cessation
- 2007-07-11 ES ES07768695.4T patent/ES2438240T3/es active Active
- 2007-07-11 CN CN2007800260153A patent/CN101490037B/zh active Active
-
2013
- 2013-04-05 US US13/857,304 patent/US8940769B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2054405B1 (en) | 2013-09-18 |
| NZ574697A (en) | 2011-12-22 |
| US20130217684A1 (en) | 2013-08-22 |
| CN101490037A (zh) | 2009-07-22 |
| CA2656810C (en) | 2012-03-13 |
| US20090209540A1 (en) | 2009-08-20 |
| MY157033A (en) | 2016-04-15 |
| CA2656810A1 (en) | 2008-01-17 |
| EP2054405A1 (en) | 2009-05-06 |
| WO2008007900A1 (en) | 2008-01-17 |
| JP2009542802A (ja) | 2009-12-03 |
| US8436022B2 (en) | 2013-05-07 |
| EP2054405A4 (en) | 2011-01-19 |
| US8940769B2 (en) | 2015-01-27 |
| AU2007273333B2 (en) | 2010-07-08 |
| CN101490037B (zh) | 2013-06-12 |
| AU2007273333A1 (en) | 2008-01-17 |
| PT2054405E (pt) | 2013-12-24 |
| ES2438240T3 (es) | 2014-01-16 |
| JP5054770B2 (ja) | 2012-10-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PL2054405T3 (pl) | Nowe pochodne biarylobenzimidazolu i zawierająca je kompozycja farmaceutyczna | |
| IL192965A0 (en) | Amido compounds and their use as pharmaceuticals | |
| IL196168A0 (en) | Biaryl compounds and pharmaceutical compositions containing the same | |
| IL242883B (en) | Aryl-amino and heteroaryl-amino converted deoxazolines and pharmaceutical preparations containing them | |
| HUS1800034I1 (hu) | Anti-FGF23 ellenanyag és anti-FGF23 ellenanyagot tartalmazó gyógyászati készítmény | |
| EP1857489A4 (en) | MICROPARTICLE AND PHARMACEUTICAL COMPOSITION | |
| IL242374A (en) | Baryl compounds and their pharmaceutical preparations | |
| EP2056835A4 (en) | PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | |
| IL200616A0 (en) | Co-crystals and pharmaceutical compositions comprising the same | |
| IL203898A0 (en) | Cdca1 peptide and pharmaceutical agent comprising the same | |
| IL193211A (en) | Derivatives of Indzol-Troaril and pharmaceutical preparations containing them | |
| EP2147671A4 (en) | COMPOSITION WITH L-CARNITINE OR DERIVATIVES AND THEIR USE | |
| EP1890677A4 (en) | PHARMACEUTICAL COMPOSITIONS AND THEIR USE | |
| EP2077262A4 (en) | IMINOPYRIDINE DERIVATIVE AND USE THEREOF | |
| PT2188258E (pt) | Compostos de nicotinamida substituídos e sua utilização em meios medicinais | |
| EP2070919A4 (en) | SPIROCHINONE COMPOUND AND PHARMACEUTICAL COMPOSITION | |
| GB0516069D0 (en) | Pharmaceutical and use thereof | |
| ZA200709687B (en) | Substituted acrylamide derivative and pharmaceutical composition comprising the same | |
| IL207423A0 (en) | Amide derivative and pharmaceutical composition containing the same | |
| GB0610090D0 (en) | Particulate drug compositions and their uses | |
| IL179669A0 (en) | Benzoimidazole derivatives and pharmaceutical compositions containing the same | |
| GB0614365D0 (en) | Pharmaceutical compositions and their use | |
| ZA200900960B (en) | Arylpiperazine derivatives and uses thereof | |
| IL192820A0 (en) | Novel compounds and use thereof | |
| EP2114404A4 (en) | COMPOUND AND PHARMACEUTICAL COMPOSITION |