PL2040703T3 - Pochodne 2-benzoilo-imidazopirydyn, sposób ich wytwarzania i ich zastosowanie w lecznictwie - Google Patents
Pochodne 2-benzoilo-imidazopirydyn, sposób ich wytwarzania i ich zastosowanie w lecznictwieInfo
- Publication number
- PL2040703T3 PL2040703T3 PL07803831T PL07803831T PL2040703T3 PL 2040703 T3 PL2040703 T3 PL 2040703T3 PL 07803831 T PL07803831 T PL 07803831T PL 07803831 T PL07803831 T PL 07803831T PL 2040703 T3 PL2040703 T3 PL 2040703T3
- Authority
- PL
- Poland
- Prior art keywords
- preparation
- imidazopyridines
- therapeutics
- benzoyl
- derivatives
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title abstract 2
- YZXCHGQUYSVNDJ-UHFFFAOYSA-N 1h-imidazo[4,5-b]pyridin-2-yl(phenyl)methanone Chemical class N=1C2=NC=CC=C2NC=1C(=O)C1=CC=CC=C1 YZXCHGQUYSVNDJ-UHFFFAOYSA-N 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 101001109698 Homo sapiens Nuclear receptor subfamily 4 group A member 2 Proteins 0.000 abstract 2
- 102100022676 Nuclear receptor subfamily 4 group A member 2 Human genes 0.000 abstract 2
- 101000785650 Homo sapiens Zinc finger protein 268 Proteins 0.000 abstract 1
- 108010093175 Member 2 Group A Nuclear Receptor Subfamily 4 Proteins 0.000 abstract 1
- 102000002559 Member 2 Group A Nuclear Receptor Subfamily 4 Human genes 0.000 abstract 1
- -1 NOT Proteins 0.000 abstract 1
- 101001109694 Rattus norvegicus Nuclear receptor subfamily 4 group A member 2 Proteins 0.000 abstract 1
- 102100026516 Zinc finger protein 268 Human genes 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000006806 disease prevention Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Psychology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Addiction (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0606010A FR2903105A1 (fr) | 2006-07-03 | 2006-07-03 | Derives de 2-benzoyl-imidazopyridines, leur preparation et leur application en therapeutique |
| PCT/FR2007/001123 WO2008003854A2 (fr) | 2006-07-03 | 2007-07-03 | Derives de 2-benzoyl-imidazopyridines, leur preparation et leur application en therapeutique |
| EP07803831A EP2040703B1 (fr) | 2006-07-03 | 2007-07-03 | Derives de 2-benzoyl-imidazopyridines, leur preparation et leur application en therapeutique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2040703T3 true PL2040703T3 (pl) | 2010-03-31 |
Family
ID=37661856
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL07803831T PL2040703T3 (pl) | 2006-07-03 | 2007-07-03 | Pochodne 2-benzoilo-imidazopirydyn, sposób ich wytwarzania i ich zastosowanie w lecznictwie |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US7902219B2 (pl) |
| EP (1) | EP2040703B1 (pl) |
| JP (1) | JP2009541469A (pl) |
| KR (1) | KR20090024775A (pl) |
| CN (1) | CN101484163A (pl) |
| AT (1) | ATE446089T1 (pl) |
| AU (1) | AU2007271082A1 (pl) |
| BR (1) | BRPI0713260A2 (pl) |
| CA (1) | CA2656045A1 (pl) |
| CY (1) | CY1109743T1 (pl) |
| DE (1) | DE602007002915D1 (pl) |
| DK (1) | DK2040703T3 (pl) |
| ES (1) | ES2335323T3 (pl) |
| FR (1) | FR2903105A1 (pl) |
| IL (1) | IL195818A0 (pl) |
| MX (1) | MX2008016558A (pl) |
| PL (1) | PL2040703T3 (pl) |
| PT (1) | PT2040703E (pl) |
| RU (1) | RU2009103300A (pl) |
| SI (1) | SI2040703T1 (pl) |
| WO (1) | WO2008003854A2 (pl) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2925905B1 (fr) * | 2008-01-02 | 2010-11-05 | Sanofi Aventis | DERIVES DE 2-BENZOYL-IMIDAZO°1,2-a!PYRIDINE, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE |
| FR2925907B1 (fr) * | 2008-01-02 | 2010-10-15 | Sanofi Aventis | DERIVES DE 2-HETEROAROYL-IMIDAZO°1,2-a!PYRIDINE, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE |
| FR2928921B1 (fr) | 2008-03-21 | 2010-04-23 | Sanofi Aventis | Derives polysubstitues de 2-aryl-6-phenyl-imidazo°1,2-a!pyridines, leur preparation et leur application en therapeutique |
| FR2928922B1 (fr) * | 2008-03-21 | 2010-04-23 | Sanofi Aventis | Derives de 2-aryl-6-phenyl-imidazo°1,2-a!pyridines polysubstitues, leur preparation et leur application en therapeutique |
| FR2928924B1 (fr) * | 2008-03-21 | 2010-04-23 | Sanofi Aventis | Derives polysubstitues de 6-heteroaryle-imidazo°1,2-a! pyridines, leur preparation et leur application en therapeutique |
| FR2928923B1 (fr) * | 2008-03-21 | 2010-04-23 | Sanofi Aventis | Derives polysubstitues de 2-heteroaryl-6-phenyl-imidazo °1,2-a!pyridines, leur preparation et leur application en therapeutiques |
| FR2933609B1 (fr) | 2008-07-10 | 2010-08-27 | Fournier Lab Sa | Utilisation de derives d'indole comme activateurs de nurr-1, pour le traitement de la maladie de parkinson. |
| FR2950053B1 (fr) | 2009-09-11 | 2014-08-01 | Fournier Lab Sa | Utilisation de derives d'indole benzoique comme activateurs de nurr-1, pour le traitement de la maladie de parkinson |
| FR2955110A1 (fr) | 2010-01-08 | 2011-07-15 | Fournier Lab Sa | Nouveaux derives de type pyrrolopyridine benzoique |
| CN103772381B (zh) * | 2013-09-16 | 2015-11-25 | 广东华南新药创制中心 | 一种四稠环喹啉类化合物及其制备方法 |
| WO2021204626A1 (en) | 2020-04-06 | 2021-10-14 | Almirall, S.A. | Aryl and heteroaryl-carboxamide substituted heteroaryl compounds as tyk2 inhibitors |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2638161B1 (fr) * | 1988-10-24 | 1991-01-11 | Centre Nat Rech Scient | Nouvelles benzoyl-2 imidazo (1,2-a) pyridines et leurs sels, leur procede de preparation, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant |
| WO2001074813A2 (en) * | 2000-03-31 | 2001-10-11 | Ortho Mcneil Pharmaceutical, Inc. | METHOD FOR USING 2- OR 3-ARYL SUBSTITUTED IMIDAZO[1,2-a] PYRIDINES AS H3 ANTAGONISTS |
| DE10117184A1 (de) | 2001-04-05 | 2002-10-17 | Gruenenthal Gmbh | Substituierte Imidazol[1,2-a]-pyridin-3-yl-amid- und -aminverbindungen |
| EP1465869B1 (en) * | 2001-12-21 | 2013-05-15 | Exelixis Patent Company LLC | Modulators of lxr |
| GB0303503D0 (en) | 2003-02-14 | 2003-03-19 | Novartis Ag | Organic compounds |
| EP1615636A1 (en) * | 2003-04-10 | 2006-01-18 | Pfizer Inc. | Bicyclic compounds as nr2b receptor antagonists |
| PE20050952A1 (es) | 2003-09-24 | 2005-12-19 | Novartis Ag | Derivados de isoquinolina como inhibidores de b-raf |
| WO2005044793A2 (en) * | 2003-10-31 | 2005-05-19 | Takeda Pharmaceutical Company Limited | Nitrogen-containing fused heterocyclic compounds |
| US20050165031A1 (en) | 2003-11-13 | 2005-07-28 | Ambit Biosciences Corporation | Urea derivatives as ABL modulators |
| BRPI0514691A (pt) | 2004-08-31 | 2008-06-17 | Astrazeneca Ab | composto ou um sal farmaceuticamente aceitável do mesmo, processo para preparar o mesmo, composição farmacêutica, e, uso de um composto ou um sal farmaceuticamente aceitável do mesmo |
| CA2589773A1 (en) | 2004-12-22 | 2006-06-29 | Astrazeneca Ab | Pyridine carboxamide derivatives for use as anticancer agents |
| WO2006067445A2 (en) | 2004-12-22 | 2006-06-29 | Astrazeneca Ab | Csf-1r kinase inhibitors |
-
2006
- 2006-07-03 FR FR0606010A patent/FR2903105A1/fr active Pending
-
2007
- 2007-07-03 PL PL07803831T patent/PL2040703T3/pl unknown
- 2007-07-03 MX MX2008016558A patent/MX2008016558A/es unknown
- 2007-07-03 SI SI200730133T patent/SI2040703T1/sl unknown
- 2007-07-03 AU AU2007271082A patent/AU2007271082A1/en not_active Abandoned
- 2007-07-03 PT PT07803831T patent/PT2040703E/pt unknown
- 2007-07-03 AT AT07803831T patent/ATE446089T1/de active
- 2007-07-03 DK DK07803831.2T patent/DK2040703T3/da active
- 2007-07-03 EP EP07803831A patent/EP2040703B1/fr not_active Not-in-force
- 2007-07-03 WO PCT/FR2007/001123 patent/WO2008003854A2/fr not_active Ceased
- 2007-07-03 RU RU2009103300/15A patent/RU2009103300A/ru not_active Application Discontinuation
- 2007-07-03 KR KR1020097000049A patent/KR20090024775A/ko not_active Withdrawn
- 2007-07-03 CA CA002656045A patent/CA2656045A1/fr not_active Abandoned
- 2007-07-03 DE DE602007002915T patent/DE602007002915D1/de active Active
- 2007-07-03 JP JP2009517330A patent/JP2009541469A/ja not_active Withdrawn
- 2007-07-03 ES ES07803831T patent/ES2335323T3/es active Active
- 2007-07-03 BR BRPI0713260-3A patent/BRPI0713260A2/pt not_active IP Right Cessation
- 2007-07-03 CN CNA2007800252640A patent/CN101484163A/zh active Pending
-
2008
- 2008-12-09 IL IL195818A patent/IL195818A0/en unknown
- 2008-12-17 US US12/336,989 patent/US7902219B2/en not_active Expired - Fee Related
-
2010
- 2010-01-20 CY CY20101100057T patent/CY1109743T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR2903105A1 (fr) | 2008-01-04 |
| EP2040703B1 (fr) | 2009-10-21 |
| WO2008003854A3 (fr) | 2008-03-06 |
| DK2040703T3 (da) | 2010-03-08 |
| IL195818A0 (en) | 2009-09-01 |
| ATE446089T1 (de) | 2009-11-15 |
| BRPI0713260A2 (pt) | 2012-04-03 |
| SI2040703T1 (sl) | 2010-02-26 |
| AU2007271082A1 (en) | 2008-01-10 |
| DE602007002915D1 (de) | 2009-12-03 |
| JP2009541469A (ja) | 2009-11-26 |
| WO2008003854A2 (fr) | 2008-01-10 |
| ES2335323T3 (es) | 2010-03-24 |
| US20090143420A1 (en) | 2009-06-04 |
| PT2040703E (pt) | 2010-01-19 |
| RU2009103300A (ru) | 2010-08-10 |
| CY1109743T1 (el) | 2014-09-10 |
| KR20090024775A (ko) | 2009-03-09 |
| EP2040703A2 (fr) | 2009-04-01 |
| CN101484163A (zh) | 2009-07-15 |
| US7902219B2 (en) | 2011-03-08 |
| MX2008016558A (es) | 2009-05-20 |
| CA2656045A1 (fr) | 2008-01-10 |
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