PL1993547T3 - Proleki kwasu benzochinolizyno-2-karboksylowego - Google Patents
Proleki kwasu benzochinolizyno-2-karboksylowegoInfo
- Publication number
- PL1993547T3 PL1993547T3 PL07713085T PL07713085T PL1993547T3 PL 1993547 T3 PL1993547 T3 PL 1993547T3 PL 07713085 T PL07713085 T PL 07713085T PL 07713085 T PL07713085 T PL 07713085T PL 1993547 T3 PL1993547 T3 PL 1993547T3
- Authority
- PL
- Poland
- Prior art keywords
- benzoquinolizine
- prodrugs
- carboxylic acid
- carboxylic
- acid
- Prior art date
Links
- ADFFPSBGYPDZAW-UHFFFAOYSA-N 4h-benzo[a]quinolizine-2-carboxylic acid Chemical compound C1=CC=C2C3=CC(C(=O)O)=CCN3C=CC2=C1 ADFFPSBGYPDZAW-UHFFFAOYSA-N 0.000 title 1
- 229940002612 prodrug Drugs 0.000 title 1
- 239000000651 prodrug Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/04—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN321MU2006 | 2006-03-07 | ||
| PCT/IB2007/000484 WO2007102061A2 (en) | 2006-03-07 | 2007-03-01 | Prodrugs of benzoquinolizine-2-carboxylic acid |
| EP07713085A EP1993547B1 (en) | 2006-03-07 | 2007-03-01 | Prodrugs of benzoquinolizine-2-carboxylic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1993547T3 true PL1993547T3 (pl) | 2013-08-30 |
Family
ID=37691768
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL07713085T PL1993547T3 (pl) | 2006-03-07 | 2007-03-01 | Proleki kwasu benzochinolizyno-2-karboksylowego |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US7868173B2 (pl) |
| EP (1) | EP1993547B1 (pl) |
| JP (1) | JP5384119B2 (pl) |
| KR (2) | KR101364900B1 (pl) |
| CN (1) | CN101500564B (pl) |
| AU (1) | AU2007222115B2 (pl) |
| BR (1) | BRPI0708606A2 (pl) |
| CA (1) | CA2644661C (pl) |
| ES (1) | ES2393802T3 (pl) |
| MX (1) | MX2008011376A (pl) |
| NZ (1) | NZ570865A (pl) |
| PL (1) | PL1993547T3 (pl) |
| RU (1) | RU2434867C2 (pl) |
| WO (1) | WO2007102061A2 (pl) |
| ZA (1) | ZA200807674B (pl) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2536408A1 (en) * | 2010-02-16 | 2012-12-26 | Wockhardt Research Centre | Efflux pump inhibitors |
| KR20140054307A (ko) * | 2011-09-28 | 2014-05-08 | 욱크하르트 리미티드 | 순수한 S-(-)-9-플루오로-6,7-디히드로-8-(4-히드록시피페리딘-1-일)-5-메틸-1-옥소-1H,-5H-벤조[i,j]퀴놀리진-2-카르복실산 L-아르기닌 염 테트라하이드레이트 및 이의 제조 방법 |
| KR20180002642A (ko) | 2015-05-08 | 2018-01-08 | 욱크하르트 리미티드 | 항박테리아제를 포함하는 안정한 약학 조성물 |
| JP2023119847A (ja) * | 2022-02-17 | 2023-08-29 | 本田技研工業株式会社 | 全固体電池 |
| CN119912446A (zh) * | 2023-10-31 | 2025-05-02 | 南京正荣医药化学有限公司 | 一种喹嗪羧酸酯类化合物及其制备方法与用途 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE793524A (fr) * | 1971-12-30 | 1973-06-29 | Riker Laboratories Inc | Acides benzoquinolizine-carboxyliques et leurs derives |
| DK160306C (da) * | 1978-08-31 | 1991-07-29 | Otsuka Pharma Co Ltd | Analogifremgangsmaade til fremstilling af piperazinylbenzoheterocycliske forbindelser eller farmaceutisk acceptable salte deraf |
| JP3029293B2 (ja) * | 1995-06-15 | 2000-04-04 | ファイザー・インコーポレーテッド | ジペプチドを含む、アザビシクロナフチリジンカルボン酸の誘導体を調製するための方法 |
| MA24500A1 (fr) * | 1997-03-21 | 1998-10-01 | Lg Life Sciences Ltd | Derive du sel d'acide carboxylique de naphthyridine . |
| US6750224B1 (en) | 1999-05-07 | 2004-06-15 | Wockhardt Limited | Antibacterial optically pure benzoquinolizine carboxylic acids, processes, compositions and methods of treatment |
| ATE415969T1 (de) * | 1999-05-07 | 2008-12-15 | Wockhardt Ltd | (s)-benzochinolizincarbonsäuren und ihre verwendung als antibakterielle mittel |
| CA2417799A1 (en) * | 2000-08-01 | 2002-02-07 | Wockhardt Limited | Inhibitors of cellular efflux pumps of microbes |
| KR100517638B1 (ko) * | 2002-04-08 | 2005-09-28 | 주식회사 엘지생명과학 | 게미플록사신 산염의 새로운 제조방법 |
| WO2005066154A2 (en) * | 2003-11-20 | 2005-07-21 | Wockhardt Limited | Polymorphs of 1-cyclopropyl-6-fuoro-8-methoxy-7-(4-amino-3, 3-dimethylpiperidin-1-yl) -1, 4-dihydro-4-oxo-quinoline-3-carboxylic acid hydrochloride and mesalyte salts |
-
2007
- 2007-03-01 PL PL07713085T patent/PL1993547T3/pl unknown
- 2007-03-01 RU RU2008139613/04A patent/RU2434867C2/ru active
- 2007-03-01 NZ NZ570865A patent/NZ570865A/en not_active IP Right Cessation
- 2007-03-01 JP JP2008557843A patent/JP5384119B2/ja active Active
- 2007-03-01 CA CA2644661A patent/CA2644661C/en not_active Expired - Fee Related
- 2007-03-01 ES ES07713085T patent/ES2393802T3/es active Active
- 2007-03-01 ZA ZA200807674A patent/ZA200807674B/xx unknown
- 2007-03-01 CN CN2007800130732A patent/CN101500564B/zh active Active
- 2007-03-01 MX MX2008011376A patent/MX2008011376A/es active IP Right Grant
- 2007-03-01 WO PCT/IB2007/000484 patent/WO2007102061A2/en not_active Ceased
- 2007-03-01 KR KR1020087024443A patent/KR101364900B1/ko not_active Expired - Fee Related
- 2007-03-01 EP EP07713085A patent/EP1993547B1/en not_active Not-in-force
- 2007-03-01 KR KR1020137029094A patent/KR20130128483A/ko not_active Withdrawn
- 2007-03-01 BR BRPI0708606-7A patent/BRPI0708606A2/pt not_active Application Discontinuation
- 2007-03-01 AU AU2007222115A patent/AU2007222115B2/en not_active Ceased
- 2007-03-09 US US11/715,921 patent/US7868173B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1993547A2 (en) | 2008-11-26 |
| RU2008139613A (ru) | 2010-04-20 |
| RU2434867C2 (ru) | 2011-11-27 |
| KR20130128483A (ko) | 2013-11-26 |
| AU2007222115A1 (en) | 2007-09-13 |
| AU2007222115B2 (en) | 2011-05-12 |
| EP1993547B1 (en) | 2012-08-22 |
| CN101500564A (zh) | 2009-08-05 |
| US20070219227A1 (en) | 2007-09-20 |
| MX2008011376A (es) | 2009-02-06 |
| JP2009529029A (ja) | 2009-08-13 |
| US7868173B2 (en) | 2011-01-11 |
| ES2393802T3 (es) | 2012-12-28 |
| CA2644661A1 (en) | 2007-09-13 |
| KR20090009795A (ko) | 2009-01-23 |
| CN101500564B (zh) | 2012-07-25 |
| BRPI0708606A2 (pt) | 2011-06-14 |
| NZ570865A (en) | 2010-11-26 |
| ZA200807674B (en) | 2009-11-25 |
| JP5384119B2 (ja) | 2014-01-08 |
| EP1993547A4 (en) | 2009-11-11 |
| WO2007102061A2 (en) | 2007-09-13 |
| CA2644661C (en) | 2013-12-31 |
| WO2007102061A3 (en) | 2009-04-23 |
| KR101364900B1 (ko) | 2014-02-19 |
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