[go: up one dir, main page]

PL1829874T3 - Tricykliczny związek i jego zastosowanie - Google Patents

Tricykliczny związek i jego zastosowanie

Info

Publication number
PL1829874T3
PL1829874T3 PL05820106T PL05820106T PL1829874T3 PL 1829874 T3 PL1829874 T3 PL 1829874T3 PL 05820106 T PL05820106 T PL 05820106T PL 05820106 T PL05820106 T PL 05820106T PL 1829874 T3 PL1829874 T3 PL 1829874T3
Authority
PL
Poland
Prior art keywords
tricyclic compound
tricyclic
compound
Prior art date
Application number
PL05820106T
Other languages
English (en)
Inventor
Junichiro Manako
Yoshifumi Kagamiishi
Masashi Kato
Kazuyuki Ohmoto
Original Assignee
Ono Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ono Pharmaceutical Co filed Critical Ono Pharmaceutical Co
Publication of PL1829874T3 publication Critical patent/PL1829874T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/438—The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL05820106T 2004-12-22 2005-12-21 Tricykliczny związek i jego zastosowanie PL1829874T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2004371033 2004-12-22
JP2005261914 2005-09-09
PCT/JP2005/023450 WO2006068164A1 (ja) 2004-12-22 2005-12-21 三環式化合物およびその用途
EP20050820106 EP1829874B1 (en) 2004-12-22 2005-12-21 Tricyclic compound and use thereof

Publications (1)

Publication Number Publication Date
PL1829874T3 true PL1829874T3 (pl) 2014-07-31

Family

ID=36601763

Family Applications (1)

Application Number Title Priority Date Filing Date
PL05820106T PL1829874T3 (pl) 2004-12-22 2005-12-21 Tricykliczny związek i jego zastosowanie

Country Status (8)

Country Link
US (4) US7964726B2 (pl)
EP (1) EP1829874B1 (pl)
JP (2) JP4997976B2 (pl)
DK (1) DK1829874T3 (pl)
ES (1) ES2459742T3 (pl)
PL (1) PL1829874T3 (pl)
PT (1) PT1829874E (pl)
WO (1) WO2006068164A1 (pl)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1637521B1 (en) * 2003-06-23 2013-06-19 Ono Pharmaceutical Co., Ltd. Novel tricyclic heterocycle compound
PL1829874T3 (pl) * 2004-12-22 2014-07-31 Ono Pharmaceutical Co Tricykliczny związek i jego zastosowanie
DE102006033114A1 (de) * 2006-07-18 2008-01-24 Grünenthal GmbH Spirocyclische Azaindol-Derivate
US20080318870A1 (en) 2007-06-19 2008-12-25 Kythera Biopharmaceuticals, Inc. Synthetic bile acid compositions and methods
US8242294B2 (en) 2007-06-19 2012-08-14 Kythera Biopharmaceuticals, Inc. Synthetic bile acid compositions and methods
JOP20180077A1 (ar) 2007-06-19 2019-01-30 Kythera Biopharmaceuticals Inc تركيبات وطرق لحمض صفراوي تخليقي
SG186826A1 (en) * 2010-07-06 2013-02-28 Ono Pharmaceutical Co Tetrahydrocarboline derivative
JP6690534B2 (ja) * 2014-06-12 2020-04-28 小野薬品工業株式会社 ストレス性疾患の予防および／または治療用医薬
US9907786B2 (en) 2014-10-21 2018-03-06 Ions Pharmaceutical S.À R.L. Therapeutic compositions containing harmine and isovanillin components, and methods of use thereof
US10092550B2 (en) 2014-10-21 2018-10-09 Ions Pharmaceutical S.À R.L. Therapeutic compositions containing curcumin, harmine, and isovanillin components, and methods of use thereof
WO2016111357A1 (ja) * 2015-01-09 2016-07-14 小野薬品工業株式会社 線維筋痛症の予防および／または治療剤
US9853612B1 (en) 2017-03-23 2017-12-26 Globalfoundries Inc. Peaking amplifier frequency tuning
US10033334B1 (en) 2017-03-23 2018-07-24 Globalfoundries Inc. Peaking amplifier frequency tuning
US12129265B2 (en) 2020-07-21 2024-10-29 Ankh Life Sciences Limited Therapeutic agents and uses thereof
EP4267578A4 (en) 2020-12-23 2024-11-20 Recurium IP Holdings, LLC ESTROGEN RECEPTOR MODULATORS

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1431702A (fr) 1964-11-23 1966-03-18 Sames Mach Electrostat Perfectionnements à l'élaboration des échantillons ou étalons utilisés en analyse radiochimique
US3959470A (en) * 1972-11-28 1976-05-25 Mikhail Davidovich Mashkovsky Psychotropic medicinal preparation
SU788471A1 (ru) 1972-11-28 1981-12-30 Всесоюзный Научно-Исследовательский Химико-Фармацевтический Институт Им.С.Орджоникидзе Психотропное средство дл лечени депрессивных состо ний "инказан
US4336260A (en) * 1977-12-08 1982-06-22 The Dow Chemical Company Method and compositions using 1-aryl-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid for treating depression
EP0357122A3 (en) * 1988-08-29 1991-10-23 Duphar International Research B.V Use of beta-carbolines, their bio-isosteric benzofuran and benzothiophene analogues for the manufacture of a medicament having cytostatic properties
JPH03287586A (ja) * 1990-04-02 1991-12-18 Taisho Pharmaceut Co Ltd テトラヒドロ―β―カルボリン誘導体
GB9401090D0 (en) 1994-01-21 1994-03-16 Glaxo Lab Sa Chemical compounds
US5403851A (en) 1994-04-05 1995-04-04 Interneuron Pharmaceuticals, Inc. Substituted tryptamines, phenalkylamines and related compounds
FR2724384B1 (fr) * 1994-09-14 1999-04-16 Cemaf Nouveaux derives de la 3,4-dihydro beta-carboline agonistes de la melatonine, leur procede de preparation et leur utilisation a titre de medicament
KR20000010918A (ko) 1996-05-10 2000-02-25 게리 엘. 윌콕스 카르볼린 유도체
PT1007067E (pt) * 1996-10-21 2002-07-31 Eurovita A S Composicoes farmaceuticas contendo partenio integrifolium ou partes dele ou um seu extracto ou componente o uso desse material vegetal para a preparacao de certos medicamentos e um processo para preparar um extracto de partenio integrifolium
DE19712201A1 (de) 1997-03-24 1998-10-01 Bodenseewerk Geraetetech Mikromechanische Spiegel-Anordnung
US6043252A (en) * 1997-05-05 2000-03-28 Icos Corporation Carboline derivatives
RU2233841C2 (ru) 1998-06-12 2004-08-10 Сосьете Де Консей Де Решерш Э Д`Аппликасьон Сьентифик Сас Бета-карболиновые соединения, фармацевтические композиции на их основе и способы связывания, достижения агонистического/антагонистического эффекта
WO2000015639A1 (en) 1998-09-16 2000-03-23 Icos Corporation Carboline derivatives as cgmp phosphodiesterase inhibitors
FR2796644B1 (fr) 1999-07-23 2001-09-07 Adir Nouveaux derives de beta-carboline, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
UA74826C2 (en) * 2000-05-17 2006-02-15 Ortho Mcneil Pharm Inc ?-carboline derivatives as phosphodiesterase inhibitors
US7488742B2 (en) * 2000-06-15 2009-02-10 Schering Corporation Thrombin receptor antagonists
MXPA02012659A (es) 2000-06-26 2003-09-22 Lilly Icos Llc Derivados de pirazindiona condensados.
JP3528968B2 (ja) * 2000-12-28 2004-05-24 小野薬品工業株式会社 三環式複素環誘導体化合物およびその化合物を有効成分とする医薬
CA2437718C (en) 2001-02-12 2010-03-16 Lilly Icos Llc Carboline derivatives
US7022856B2 (en) * 2001-02-12 2006-04-04 Lilly Icos Llc. Carboline derivatives
GB0108337D0 (en) * 2001-04-03 2001-05-23 Novartis Ag Organic compounds
EP1383765B1 (en) * 2001-04-25 2006-12-13 Lilly Icos LLC Carboline derivatives as inhibitors of phosphodiesterase 5 (PDE5) for the treatment of cardiovascular diseases and erectile dysfunction
WO2003030937A1 (en) 2001-10-05 2003-04-17 Ono Pharmaceutical Co., Ltd. Remedies for stress diseases comprising mitochondrial benzodiazepine receptor antagonists
SE520453C2 (sv) * 2001-11-01 2003-07-15 Alfa Laval Corp Ab En apparat för samtidig rening av en vätska och en gas
JPWO2003068753A1 (ja) 2002-02-14 2005-06-02 小野薬品工業株式会社 Ｎ−カルバモイル窒素含有縮合環化合物およびその化合物を有効成分として含有する薬剤
TWI329111B (en) 2002-05-24 2010-08-21 X Ceptor Therapeutics Inc Azepinoindole and pyridoindole derivatives as pharmaceutical agents
EP1637521B1 (en) * 2003-06-23 2013-06-19 Ono Pharmaceutical Co., Ltd. Novel tricyclic heterocycle compound
US7855295B2 (en) 2004-01-23 2010-12-21 Novartis Vaccines And Diagnostics, Inc. Tetrahydrocarboline compounds as anticancer agents
ES2401335T3 (es) 2004-03-15 2013-04-18 Ptc Therapeutics, Inc. Derivados de carbolina útiles en la inhibición de la angiogénesis
US7403851B2 (en) * 2004-09-30 2008-07-22 Navteq North America, Llc Method of operating a navigation system to report effects of updated portions of a geographic database
PL1829874T3 (pl) * 2004-12-22 2014-07-31 Ono Pharmaceutical Co Tricykliczny związek i jego zastosowanie

Also Published As

Publication number Publication date
US20110207700A1 (en) 2011-08-25
US20080114012A1 (en) 2008-05-15
EP1829874B1 (en) 2014-02-12
WO2006068164A1 (ja) 2006-06-29
ES2459742T3 (es) 2014-05-12
EP1829874A4 (en) 2010-01-06
JP5652417B2 (ja) 2015-01-14
US8476293B2 (en) 2013-07-02
US7964726B2 (en) 2011-06-21
PT1829874E (pt) 2014-04-10
JP4997976B2 (ja) 2012-08-15
US20130252993A1 (en) 2013-09-26
EP1829874A1 (en) 2007-09-05
JPWO2006068164A1 (ja) 2008-06-12
JP2012126737A (ja) 2012-07-05
US20150105415A1 (en) 2015-04-16
DK1829874T3 (da) 2014-05-12
US8952158B2 (en) 2015-02-10

Similar Documents

Publication Publication Date Title
EP1802588A4 (en) SUBSTITUTED AMINOPYRIMIDONE AND APPLICATIONS THEREOF
ZA200701820B (en) Substituted phenylaminothiazoles and use thereof
EP1790639A4 (en) A BASIC GROUP CONNECTING AND APPLYING THEREOF
EP1829874A4 (en) TRICYCLIC COMPOUND AND ITS USE
PL1755392T3 (pl) Związki izoflawonoidowe i ich zastosowanie
EP1778214A4 (en) NEW BIPHENYL COMPOUNDS AND THEIR USE
IL179497A0 (en) Carboranylporphyrins and uses thereof
PL2215908T3 (pl) 2-alkilo-cykloalk(en)ylo-karboksamidy i ich zastosowanie jako fungicydów
IL180365A0 (en) Carboranylporphyrins and uses thereof
ZA200609075B (en) Isoflavonoid compounds and use thereof
EP1810976A4 (en) BENZONAPHTHACENEGLYCOSIDE DERIVATIVE AND THE USE THEREOF
GB0427723D0 (en) Compounds and their use
GB0401244D0 (en) Compounds and their use
GB0402903D0 (en) Compounds and their use
GB0423234D0 (en) Compounds and their use
GB0411071D0 (en) Compounds and their use
GB0402905D0 (en) Compounds and their use
GB0410831D0 (en) Compounds and their use
GB0405306D0 (en) Compounds and their use
GB0407628D0 (en) Compounds and their use
GB0416630D0 (en) Compounds and their use
GB0410833D0 (en) Compounds and their use
GB0403953D0 (en) Compounds and their use
GB0410830D0 (en) Compounds and their use
GB0410114D0 (en) Compounds and their use