PL1899350T3 - Pochodne pirazolo[3,4-d]azepiny jako antagoniści histaminy H3 - Google Patents

Pochodne pirazolo[3,4-d]azepiny jako antagoniści histaminy H3

Info

Publication number: PL1899350T3
Authority: PL; Poland
Prior art keywords: antagonists; pyrazolo; histamine; azepine derivatives; derivatives
Prior art date: 2005-07-06

Application number

PL06818218T

Other languages

English (en)

Inventor

Mark James Bamford

David Matthew Wilson

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-07-06

Filing date

2006-07-04

Publication date

2010-10-29

2006-07-04 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

2010-10-29 Publication of PL1899350T3 publication Critical patent/PL1899350T3/pl

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
Life Sciences & Earth Sciences (AREA)
Biomedical Technology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Neurology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

PL06818218T 2005-07-06 2006-07-04 Pochodne pirazolo[3,4-d]azepiny jako antagoniści histaminy H3 PL1899350T3 (pl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GBGB0513886.2A GB0513886D0 (en)	2005-07-06	2005-07-06	Novel compounds
EP06818218A EP1899350B1 (en)	2005-07-06	2006-07-04	Pyrazolo [3 , 4-d]azepine derivatives as histamine h3 antagonists
PCT/EP2006/006613 WO2007025596A1 (en)	2005-07-06	2006-07-04	Pyrazolo [3 , 4-d] azepine derivatives as histamine h3 antagonists

Publications (1)

Publication Number	Publication Date
PL1899350T3 true PL1899350T3 (pl)	2010-10-29

Family

ID=34856781

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL06818218T PL1899350T3 (pl)	2005-07-06	2006-07-04	Pochodne pirazolo[3,4-d]azepiny jako antagoniści histaminy H3

Country Status (27)

Country	Link
US (1)	US7888347B2 (pl)
EP (1)	EP1899350B1 (pl)
JP (1)	JP5145218B2 (pl)
KR (1)	KR20080037651A (pl)
CN (1)	CN101258154B (pl)
AT (1)	ATE467636T1 (pl)
AU (1)	AU2006286897A1 (pl)
BR (1)	BRPI0612719A2 (pl)
CA (1)	CA2614232A1 (pl)
CR (1)	CR9622A (pl)
CY (1)	CY1110711T1 (pl)
DE (1)	DE602006014273D1 (pl)
DK (1)	DK1899350T3 (pl)
EA (1)	EA013600B1 (pl)
ES (1)	ES2345841T3 (pl)
GB (1)	GB0513886D0 (pl)
HR (1)	HRP20100401T1 (pl)
IL (1)	IL188184A0 (pl)
MA (1)	MA29623B1 (pl)
MX (1)	MX2008000383A (pl)
NO (1)	NO20080563L (pl)
PL (1)	PL1899350T3 (pl)
PT (1)	PT1899350E (pl)
SI (1)	SI1899350T1 (pl)
UA (1)	UA93047C2 (pl)
WO (1)	WO2007025596A1 (pl)
ZA (1)	ZA200710798B (pl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US9108948B2 (en)	2006-06-23	2015-08-18	Abbvie Inc.	Cyclopropyl amine derivatives
US8829041B2 (en)	2006-06-23	2014-09-09	Abbvie Inc.	Cyclopropyl amine derivatives
MX2010002938A (es)	2007-09-24	2010-04-01	Comentis Inc	Derivados de (3-hidroxi-4-amino-butan-2-il)-3-(2-tiazol-2-il-pirro lidin-1-carbonil)benzamida y compuestos relacionados como inhibidores de beta-secretasa para tratar enfermedad de alzheimer.
US9186353B2 (en) *	2009-04-27	2015-11-17	Abbvie Inc.	Treatment of osteoarthritis pain
WO2012037258A1 (en)	2010-09-16	2012-03-22	Abbott Laboratories	Processes for preparing 1,2-substituted cyclopropyl derivatives
CN102952139B (zh) *	2011-08-30	2016-08-10	上海药明康德新药开发有限公司	反式-3a-氟吡咯烷[3,4-C]并环化合物及其制备方法
WO2013151982A1 (en)	2012-04-03	2013-10-10	Arena Pharmaceuticals, Inc.	Methods and compounds useful in treating pruritus, and methods for identifying such compounds
EP2647377A1 (en)	2012-04-06	2013-10-09	Sanofi	Use of an h3 receptor antagonist for the treatment of alzheimer's disease
JO3407B1 (ar)	2012-05-31	2019-10-20	Eisai R&D Man Co Ltd	مركبات رباعي هيدرو بيرازولو بيريميدين
US9910887B2 (en) *	2013-04-25	2018-03-06	Facebook, Inc.	Variable search query vertical access
BR112018074231A2 (pt) *	2016-05-25	2019-03-06	Akarna Therapeutics, Ltd.	compostos bicíclicos fundidos para o tratamento de doença

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6573218B1 (en) *	1998-09-09	2003-06-03	Ishihara Sangyo Kaisha, Ltd.	Fused-benzene derivatives useful as herbicides
EP1173438A1 (en) *	1999-04-16	2002-01-23	Novo Nordisk A/S	Substituted imidazoles, their preparation and use
JP2001220390A (ja)	2000-02-09	2001-08-14	Yamanouchi Pharmaceut Co Ltd	縮合ピラゾール誘導体
DE60312328T2 (de) *	2002-06-06	2007-11-08	Novo Nordisk A/S	Substituierte hexahydropyrrolo(1,2-a)pyrazine, octahydropyrido(1,2-a)pyrazine und decahydropyrazino(1,2-a)azepine
US6770597B2 (en)	2002-07-17	2004-08-03	Ishihara Sangyo Kaisha, Ltd.	Benzohydrazide derivatives as herbicides and desiccant compositions containing them
AU2003244649A1 (en)	2002-07-25	2004-02-23	Pharmacia Italia Spa	Bicyclo-pyrazoles active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them
EP1539704A1 (en) *	2002-08-20	2005-06-15	Eli Lilly And Company	Substituted azepines as histamine h3 receptor antagonists, preparation and therapeutic uses
GB0224083D0 (en)	2002-10-16	2002-11-27	Glaxo Group Ltd	Novel compounds
GB0224557D0 (en)	2002-10-22	2002-11-27	Glaxo Group Ltd	Novel compounds
ATE441417T1 (de)	2002-12-20	2009-09-15	Glaxo Group Ltd	Benzoädüazepinderivate für die behandlung von neurologischen krankheiten
AU2004283196B2 (en) *	2003-09-17	2011-08-25	Janssen Pharmaceutica, N.V.	Fused heterocyclic compounds
GB0329214D0 (en)	2003-12-17	2004-01-21	Glaxo Group Ltd	Novel compounds
GB0405628D0 (en)	2004-03-12	2004-04-21	Glaxo Group Ltd	Novel compounds
GB0408083D0 (en)	2004-04-08	2004-05-12	Glaxo Group Ltd	Novel compounds
US20070232590A1 (en)	2004-06-18	2007-10-04	Glaxo Group Limited	3-Cylcoalkylbenzazepines as Histamine H3 Antagonists
GB0418267D0 (en)	2004-08-16	2004-09-15	Glaxo Group Ltd	Novel compounds
AU2005313550A1 (en)	2004-12-07	2006-06-15	Glaxo Group Limited	Indenyl derivatives and use thereof for the treatment of neurological disorders
EP1858900B1 (en)	2005-03-14	2009-01-07	Glaxo Group Limited	Fused thiazole derivatives having affinity for the histamine h3 receptor

2005
- 2005-07-06 GB GBGB0513886.2A patent/GB0513886D0/en not_active Ceased
2006
- 2006-07-04 BR BRPI0612719-3A patent/BRPI0612719A2/pt not_active IP Right Cessation
- 2006-07-04 AU AU2006286897A patent/AU2006286897A1/en not_active Abandoned
- 2006-07-04 EP EP06818218A patent/EP1899350B1/en active Active
- 2006-07-04 HR HR20100401T patent/HRP20100401T1/hr unknown
- 2006-07-04 JP JP2008519862A patent/JP5145218B2/ja not_active Expired - Fee Related
- 2006-07-04 DK DK06818218.7T patent/DK1899350T3/da active
- 2006-07-04 US US11/994,689 patent/US7888347B2/en not_active Expired - Fee Related
- 2006-07-04 DE DE602006014273T patent/DE602006014273D1/de active Active
- 2006-07-04 PT PT06818218T patent/PT1899350E/pt unknown
- 2006-07-04 UA UAA200800190A patent/UA93047C2/ru unknown
- 2006-07-04 ES ES06818218T patent/ES2345841T3/es active Active
- 2006-07-04 CA CA002614232A patent/CA2614232A1/en not_active Abandoned
- 2006-07-04 MX MX2008000383A patent/MX2008000383A/es active IP Right Grant
- 2006-07-04 EA EA200800264A patent/EA013600B1/ru not_active IP Right Cessation
- 2006-07-04 KR KR1020087000265A patent/KR20080037651A/ko not_active Ceased
- 2006-07-04 SI SI200630733T patent/SI1899350T1/sl unknown
- 2006-07-04 CN CN2006800322776A patent/CN101258154B/zh not_active Expired - Fee Related
- 2006-07-04 AT AT06818218T patent/ATE467636T1/de active
- 2006-07-04 PL PL06818218T patent/PL1899350T3/pl unknown
- 2006-07-04 WO PCT/EP2006/006613 patent/WO2007025596A1/en not_active Ceased
2007
- 2007-12-12 ZA ZA200710798A patent/ZA200710798B/xx unknown
- 2007-12-17 IL IL188184A patent/IL188184A0/en unknown
- 2007-12-20 CR CR9622A patent/CR9622A/es not_active Application Discontinuation
2008
- 2008-01-09 MA MA30562A patent/MA29623B1/fr unknown
- 2008-01-30 NO NO20080563A patent/NO20080563L/no not_active Application Discontinuation
2010
- 2010-07-29 CY CY20101100713T patent/CY1110711T1/el unknown

Also Published As

Publication number	Publication date
BRPI0612719A2 (pt)	2010-11-30
CR9622A (es)	2008-04-10
US7888347B2 (en)	2011-02-15
JP5145218B2 (ja)	2013-02-13
UA93047C2 (ru)	2011-01-10
WO2007025596A1 (en)	2007-03-08
ATE467636T1 (de)	2010-05-15
DE602006014273D1 (de)	2010-06-24
JP2009500366A (ja)	2009-01-08
EP1899350B1 (en)	2010-05-12
ZA200710798B (en)	2008-11-26
EA200800264A1 (ru)	2008-06-30
EP1899350A1 (en)	2008-03-19
SI1899350T1 (sl)	2010-09-30
CN101258154A (zh)	2008-09-03
US20080176832A1 (en)	2008-07-24
AU2006286897A1 (en)	2007-03-08
CA2614232A1 (en)	2007-03-08
IL188184A0 (en)	2008-03-20
KR20080037651A (ko)	2008-04-30
EA013600B1 (ru)	2010-06-30
GB0513886D0 (en)	2005-08-10
ES2345841T3 (es)	2010-10-04
CY1110711T1 (el)	2015-06-10
MA29623B1 (fr)	2008-07-01
NO20080563L (no)	2008-02-01
MX2008000383A (es)	2008-03-07
DK1899350T3 (da)	2010-09-06
PT1899350E (pt)	2010-07-21
HRP20100401T1 (hr)	2010-09-30
CN101258154B (zh)	2011-01-19

Publication	Publication Date	Title
GB0329214D0 (en)	2004-01-21	Novel compounds
IL188184A0 (en)	2008-03-20	Pyrazolo [3,4-d] azepine derivatives as histamine h3 antagonists
TW200500344A (en)	2005-01-01	Novel compounds
DE602006005477D1 (en)	2009-04-16	Imidazopyridinverbindungen
TW200503713A (en)	2005-02-01	Novel compounds
TW200621716A (en)	2006-07-01	Novel compounds
TW200503710A (en)	2005-02-01	Novel compounds
MX2010006748A (es)	2010-08-18	Pirazolo[1,5-a]pirimidinas utiles como inhibidores de jak2.
GEP20135780B (en)	2013-03-11	Novel pyrazolo [3,4-d] pyrimidine derivatives as anti-cancer agents
TW200514781A (en)	2005-05-01	Novel compounds
TW200730525A (en)	2007-08-16	Therapeutic agents
IL185869A0 (en)	2008-01-06	Fused thiazole derivatives having affinity for the histamine h3 receptor
TW200611701A (en)	2006-04-16	Novel compounds
GB0420831D0 (en)	2004-10-20	Novel compounds
MX2007006754A (es)	2007-07-09	Derivados de indenilo y uso de los mismos para el tratamiento de trastornos neurologicos.
MXPA05011163A (es)	2005-12-14	Derivados de 3-benzhidriliden-8-azabiciclo[3.2.1]octano con actividad de receptores opioides.
WO2005097778A8 (en)	2005-12-22	Tetrahydrobenzazepines as histamine h3 receptor ligands
TW200621255A (en)	2006-07-01	Novel compounds
WO2004056821A3 (en)	2004-08-12	Quinolizidine derivatives