PL1737438T3 - Pochodne Alfa-aminoamidu użyteczne do leczenia zespołu niespokojnych nóg - Google Patents

Pochodne Alfa-aminoamidu użyteczne do leczenia zespołu niespokojnych nóg

Info

Publication number: PL1737438T3
Authority: PL; Poland
Prior art keywords: treatment; alpha; derivatives useful; restless legs; legs syndrome
Prior art date: 2004-04-22

Application number

PL05736365T

Other languages

English (en)

Inventor

Claudia Besana

Elena Barbanti

Emanuela Izzo

Florian Thaler

Ruggero Fariello

Patricia Salvati

Luca Benatti

Original Assignee

Newron Pharm Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-04-22

Filing date

2005-04-19

Publication date

2009-01-30

2005-04-19 Application filed by Newron Pharm Spa filed Critical Newron Pharm Spa

2009-01-30 Publication of PL1737438T3 publication Critical patent/PL1737438T3/pl

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Chemical Kinetics & Catalysis (AREA)
Addiction (AREA)
Psychiatry (AREA)
Psychology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)

PL05736365T 2004-04-22 2005-04-19 Pochodne Alfa-aminoamidu użyteczne do leczenia zespołu niespokojnych nóg PL1737438T3 (pl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
EP04009532A EP1588704A1 (en)	2004-04-22	2004-04-22	Alpha-aminoamide derivatives useful in the treatment of restless legs syndrome and addictive disorders
PCT/EP2005/004166 WO2005102300A1 (en)	2004-04-22	2005-04-19	α-AMINOAMIDE DERIVATIVES USEFUL IN THE TREATMENT OF RESTLESS LEGS SYNDROME AND ADDICTIVE DISORDERS
EP05736365A EP1737438B1 (en)	2004-04-22	2005-04-19	Alpha-aminoamide derivatives useful in the treatment of restless legs syndrome

Publications (1)

Publication Number	Publication Date
PL1737438T3 true PL1737438T3 (pl)	2009-01-30

Family

ID=34924693

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
PL05736365T PL1737438T3 (pl)	2004-04-22	2005-04-19	Pochodne Alfa-aminoamidu użyteczne do leczenia zespołu niespokojnych nóg
PL07022078T PL1900362T3 (pl)	2004-04-22	2005-04-19	Pochodne alfa-aminoamidu użyteczne w leczeniu zaburzeń uzależnieniowych

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
PL07022078T PL1900362T3 (pl)	2004-04-22	2005-04-19	Pochodne alfa-aminoamidu użyteczne w leczeniu zaburzeń uzależnieniowych

Country Status (25)

Country	Link
US (2)	US8445513B2 (pl)
EP (3)	EP1588704A1 (pl)
JP (1)	JP5020069B2 (pl)
KR (2)	KR101195819B1 (pl)
CN (1)	CN1942179B (pl)
AT (2)	ATE494890T1 (pl)
AU (1)	AU2005235428B2 (pl)
BR (2)	BRPI0509976B8 (pl)
CA (1)	CA2563674C (pl)
CY (2)	CY1108494T1 (pl)
DE (2)	DE602005025941D1 (pl)
DK (2)	DK1737438T3 (pl)
ES (2)	ES2357559T3 (pl)
HR (2)	HRP20080593T3 (pl)
IL (1)	IL178732A (pl)
ME (2)	ME01219B (pl)
MX (1)	MXPA06012163A (pl)
NO (2)	NO337900B1 (pl)
NZ (1)	NZ550664A (pl)
PL (2)	PL1737438T3 (pl)
PT (2)	PT1900362E (pl)
RS (2)	RS51791B (pl)
RU (1)	RU2403030C2 (pl)
SI (2)	SI1737438T1 (pl)
WO (1)	WO2005102300A1 (pl)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9727523D0 (en)	1997-12-31	1998-02-25	Pharmacia & Upjohn Spa	Alpha-aminoamide derivatives useful as analgesic agents
PT1423168E (pt) *	2001-09-03	2006-05-31	Newron Pharm Spa	Composicao farmaceutica que compreende gabapentina ou um seu analogo e uma x-aminoamida e a sua utilizacao como analgesico
EP1438956A1 (en) *	2003-01-16	2004-07-21	Newron Pharmaceuticals S.p.A.	Alpha-aminoamide derivatives useful as antimigraine agents
US20070276046A1 (en) *	2003-08-25	2007-11-29	Patricia Salvati	Alpha-Aminoamide Derivatives Useful as Anti-Inflammatory Agents
EP1588704A1 (en)	2004-04-22	2005-10-26	Newron Pharmaceuticals S.p.A.	Alpha-aminoamide derivatives useful in the treatment of restless legs syndrome and addictive disorders
DK1809271T5 (da) *	2004-09-10	2010-12-06	Newron Pharm Spa	Anvendelse af (R)-(halogenbenzyloxy)benzylaminopropanamider som natrium- og/eller calciumkanalselektive modulatorer
US20060173074A1 (en) *	2004-11-10	2006-08-03	Juha Ellmen	Treatment of restless legs syndrome
SI1963280T1 (sl)	2005-12-22	2016-02-29	Newron Pharmaceuticals S.P.A.	2-feniletilamino derivati kot modulatorji kalcijevih in/ali natrijevih kanalčkov
EP2007369A4 (en)	2006-04-03	2009-07-01	Teva Pharma	USE OF RASAGILINE FOR THE TREATMENT OF LEG SYNDROME WITHOUT REST
EP1870097A1 (en)	2006-06-15	2007-12-26	Newron Pharmaceuticals S.p.A.	Alpha-aminoamide derivatives useful in the treatment of cognitive disorders
EP2029524B1 (en)	2006-06-19	2014-11-26	Newron Pharmaceuticals S.p.A.	Process for the production of 2- [4 - ( 3- and 2-fluorobenzyloxy) benzylamino] propan amides
GB0706630D0 (en) *	2007-04-04	2007-05-16	Glaxo Group Ltd	Novel compounds
WO2008151702A1 (en) *	2007-06-15	2008-12-18	Newron Pharmaceuticals S.P.A.	Substituted 2- [2- (phenyl) ethylamino] alkaneamide derivatives and their use as sodium and/or calcium channel modulators
LT2229351T (lt)	2007-12-11	2018-01-25	Newron Pharmaceuticals S.P.A.	Didelio grynumo laipsnio 2-[4-(3- arba 2-fluorbenziloksi)benzilamino]propanamidų gamybos būdas
NZ586182A (en) *	2007-12-19	2012-02-24	Newron Pharm Spa	Alpha-aminoamide derivatives useful in the treatment of psychiatric disorders
EP2314569A1 (en)	2009-10-22	2011-04-27	Merck Patent GmbH	Novel polymorphic forms of (S)-2-[4-(3-Fluoro-benzyloxy)-benzylamino]-propionamide mesylate salt and processes of manufacturing thereof
CA2794389C (en)	2010-04-27	2016-08-23	Newron Pharmaceuticals S.P.A.	Process for the production of ralfinamide methanesulfonate salts or their r-enantiomers
US11278651B2 (en)	2018-10-17	2022-03-22	Gambro Lundia Ab	Membrane and device for treating restless leg syndrome
CN114667963B (zh) *	2020-12-24	2024-04-26	中国科学院脑科学与智能技术卓越创新中心	一种非人灵长类动物药物成瘾性评估的装置

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1140748A (en)	1966-06-23	1969-01-22	Ici Ltd	New carboxylic acid derivatives
US4049663A (en) *	1972-06-06	1977-09-20	Allen & Hanburys Limited	Ethylene diamine derivatives
FR2480747A1 (fr) *	1980-04-17	1981-10-23	Roques Bernard	Derives d'acides amines et leur application therapeutique
US4935429A (en) *	1985-10-25	1990-06-19	Dackis Charles A	Method of treating psychostimulant addiction
CA1336169C (en) *	1988-03-01	1995-07-04	Walther Birkmayer	Agent for treatment of parkinson's disease
IL94466A (en) *	1989-05-25	1995-01-24	Erba Carlo Spa	Pharmaceutical preparations containing the history of A-amino carboxamide N-phenylalkyl are converted into such new compounds and their preparation
US5221536A (en) *	1990-05-07	1993-06-22	Alza Corporation	Dosage form indicated for the management of abnormal posture, tremor and involuntary movement
EP0520325A1 (de) *	1991-06-28	1992-12-30	F.Hoffmann-La Roche & Co. Aktiengesellschaft	Verwendung von Monoaminoxidase-B-Hemmern zur Verhütung und Behandlung von Entzugserscheinungen nach Alkohol- und Drogenmissbrauch
GB9306886D0 (en)	1993-04-01	1993-05-26	Erba Carlo Spa	Substituted (arylakoxybenzyl) aminopropanamide derivatives and process for their preparation
IL111240A (en) *	1993-10-18	2001-10-31	Teva Pharma	Salts of r(+) - enantiomers of n- propargyl-1-aminoindan and pharmaceutical compositions comprising them
WO1996037226A2 (en) *	1995-05-26	1996-11-28	Pfizer Inc.	Combinations for the treatment of parkinsonism containing selective nmda antagonists
WO1997000511A1 (de)	1995-06-17	1997-01-03	Baumann Guenter	Scheibenkörper
GB9515412D0 (en) *	1995-07-27	1995-09-27	Pharmacia Spa	2-(4-substituted)-benzylamino-2-methyl-propanamide derivatives
GB9515411D0 (en)	1995-07-27	1995-09-27	Pharmacia Spa	N-(4-substituted-benzyl)-2-aminolactam derivatives
DE19701619B4 (de) *	1997-01-17	2007-10-11	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Verwendung von Pramipexol zur Behandlung des restless legs syndroms
GB9727523D0 (en)	1997-12-31	1998-02-25	Pharmacia & Upjohn Spa	Alpha-aminoamide derivatives useful as analgesic agents
GB9727521D0 (en)	1997-12-31	1998-02-25	Pharmacia & Upjohn Spa	Substituted 2-benzylamino-2-phenyl-acetamide compounds
EP1047756A2 (en)	1998-01-12	2000-11-02	Deborah Wenzel	An additive composition also used as a fuel composition comprising water soluble alcohols
FI109453B (fi) *	1999-06-30	2002-08-15	Orion Yhtymae Oyj	Farmaseuttinen koostumus
AU1359801A (en) *	1999-11-05	2001-06-06	Vela Pharmaceuticals Inc.	Methods and compositions for treating reward deficiency syndrome
WO2001041763A1 (en) *	1999-12-10	2001-06-14	University Of Cincinnati	Treatment of addiction disorders
US20020019421A1 (en) *	2000-07-05	2002-02-14	Roni Biberman	Compositions and therapy for substance addiction
WO2002100350A2 (en) *	2001-06-13	2002-12-19	The Regents Of University Of Michigan	Dopamine receptor ligands and therapeutic methods based thereon
CA2486380C (en) *	2002-05-29	2011-10-25	F. Hoffmann-La Roche Ag	N-acylaminobenzene dervatives as selective monoamine oxidase b inhibitors
DE60303936T2 (de)	2002-06-24	2006-12-28	Rockwool International A/S	Verfahren und vorrichtung zum regeln der herstellung von mineralwolle mittels eines kaskadenrotors
US6900354B2 (en) *	2002-07-15	2005-05-31	Hoffman-La Roche Inc.	3-phenyl-propionamido, 3-phenyl-acrylamido and 3-phenyl-propynamido derivatives
AR044007A1 (es)	2003-04-11	2005-08-24	Newron Pharmaceuticals Inc	Metodos para el tratamiento de la enfermedad de parkinson
JP2005060370A (ja) *	2003-07-25	2005-03-10	Kyowa Hakko Kogyo Co Ltd	医薬組成物
EP1524267A1 (en) *	2003-10-15	2005-04-20	Newron Pharmaceuticals S.p.A.	Substituted benzylaminoalkylene heterocycles
EP1588704A1 (en)	2004-04-22	2005-10-26	Newron Pharmaceuticals S.p.A.	Alpha-aminoamide derivatives useful in the treatment of restless legs syndrome and addictive disorders

2004
- 2004-04-22 EP EP04009532A patent/EP1588704A1/en not_active Withdrawn
2005
- 2005-04-19 EP EP07022078A patent/EP1900362B1/en not_active Expired - Lifetime
- 2005-04-19 PT PT07022078T patent/PT1900362E/pt unknown
- 2005-04-19 PL PL05736365T patent/PL1737438T3/pl unknown
- 2005-04-19 DK DK05736365T patent/DK1737438T3/da active
- 2005-04-19 DE DE602005025941T patent/DE602005025941D1/de not_active Expired - Lifetime
- 2005-04-19 MX MXPA06012163A patent/MXPA06012163A/es active IP Right Grant
- 2005-04-19 DE DE602005009162T patent/DE602005009162D1/de not_active Expired - Lifetime
- 2005-04-19 RS RS20110128A patent/RS51791B/sr unknown
- 2005-04-19 SI SI200530430T patent/SI1737438T1/sl unknown
- 2005-04-19 ES ES07022078T patent/ES2357559T3/es not_active Expired - Lifetime
- 2005-04-19 KR KR1020067021748A patent/KR101195819B1/ko not_active Expired - Lifetime
- 2005-04-19 US US11/578,988 patent/US8445513B2/en not_active Expired - Lifetime
- 2005-04-19 ME MEP-2011-56A patent/ME01219B/me unknown
- 2005-04-19 ME MEP-2016-18A patent/ME02324B/me unknown
- 2005-04-19 PT PT05736365T patent/PT1737438E/pt unknown
- 2005-04-19 HR HR20080593T patent/HRP20080593T3/xx unknown
- 2005-04-19 RU RU2006137079/15A patent/RU2403030C2/ru active
- 2005-04-19 WO PCT/EP2005/004166 patent/WO2005102300A1/en not_active Ceased
- 2005-04-19 CA CA2563674A patent/CA2563674C/en not_active Expired - Lifetime
- 2005-04-19 DK DK07022078.5T patent/DK1900362T3/da active
- 2005-04-19 ES ES05736365T patent/ES2313330T3/es not_active Expired - Lifetime
- 2005-04-19 NZ NZ550664A patent/NZ550664A/en not_active IP Right Cessation
- 2005-04-19 BR BRPI0509976A patent/BRPI0509976B8/pt active IP Right Grant
- 2005-04-19 SI SI200531224T patent/SI1900362T1/sl unknown
- 2005-04-19 AU AU2005235428A patent/AU2005235428B2/en not_active Expired
- 2005-04-19 KR KR1020127003440A patent/KR101238377B1/ko not_active Expired - Lifetime
- 2005-04-19 EP EP05736365A patent/EP1737438B1/en not_active Expired - Lifetime
- 2005-04-19 JP JP2007508825A patent/JP5020069B2/ja not_active Expired - Lifetime
- 2005-04-19 BR BR122020004541-8A patent/BR122020004541B1/pt active IP Right Grant
- 2005-04-19 RS RSP-2008/0531A patent/RS50667B/sr unknown
- 2005-04-19 AT AT07022078T patent/ATE494890T1/de active
- 2005-04-19 PL PL07022078T patent/PL1900362T3/pl unknown
- 2005-04-19 AT AT05736365T patent/ATE405256T1/de active
- 2005-04-19 CN CN2005800118905A patent/CN1942179B/zh not_active Expired - Lifetime
2006
- 2006-10-19 IL IL178732A patent/IL178732A/en active IP Right Grant
- 2006-10-19 NO NO20064732A patent/NO337900B1/no unknown
2008
- 2008-11-10 CY CY20081101279T patent/CY1108494T1/el unknown
2011
- 2011-03-04 CY CY20111100255T patent/CY1111656T1/el unknown
- 2011-03-30 HR HR20110230T patent/HRP20110230T1/hr unknown
2013
- 2013-03-15 US US13/835,445 patent/US8697738B2/en not_active Expired - Lifetime
2015
- 2015-07-27 NO NO20150971A patent/NO338870B1/no unknown

Also Published As

Publication number	Publication date
KR20070042914A (ko)	2007-04-24
PT1900362E (pt)	2011-03-09
PL1900362T3 (pl)	2011-06-30
DE602005009162D1 (de)	2008-10-02
HRP20080593T3 (en)	2008-12-31
JP5020069B2 (ja)	2012-09-05
SI1900362T1 (sl)	2011-03-31
KR101195819B1 (ko)	2012-11-05
CA2563674C (en)	2012-12-18
EP1737438A1 (en)	2007-01-03
US20130217747A1 (en)	2013-08-22
IL178732A0 (en)	2007-05-15
EP1900362A3 (en)	2009-04-01
NO20150971L (no)	2006-11-22
AU2005235428B2 (en)	2010-03-18
ES2357559T3 (es)	2011-04-27
BR122020004541B1 (pt)	2021-11-09
DK1900362T3 (da)	2011-05-09
CN1942179B (zh)	2010-08-11
KR20120028399A (ko)	2012-03-22
PT1737438E (pt)	2008-12-22
WO2005102300A1 (en)	2005-11-03
ES2313330T3 (es)	2009-03-01
RS50667B (sr)	2010-06-30
IL178732A (en)	2013-01-31
BRPI0509976B8 (pt)	2021-05-25
RS51791B (sr)	2011-12-31
CY1111656T1 (el)	2015-10-07
RU2403030C2 (ru)	2010-11-10
MXPA06012163A (es)	2007-01-17
RU2006137079A (ru)	2008-04-27
ATE405256T1 (de)	2008-09-15
CA2563674A1 (en)	2005-11-03
AU2005235428A1 (en)	2005-11-03
ATE494890T1 (de)	2011-01-15
US8697738B2 (en)	2014-04-15
HK1099216A1 (en)	2007-08-10
EP1900362B1 (en)	2011-01-12
CN1942179A (zh)	2007-04-04
DE602005025941D1 (de)	2011-02-24
US20070203182A1 (en)	2007-08-30
EP1900362A2 (en)	2008-03-19
HRP20110230T1 (hr)	2011-04-30
ME02324B (me)	2016-06-20
US8445513B2 (en)	2013-05-21
NO20064732L (no)	2006-11-22
ME01219B (me)	2013-06-20
BRPI0509976A (pt)	2007-10-16
JP2007533691A (ja)	2007-11-22
CY1108494T1 (el)	2014-04-09
NO338870B1 (no)	2016-10-31
NO337900B1 (no)	2016-07-04
KR101238377B1 (ko)	2013-03-04
DK1737438T3 (da)	2008-12-08
BRPI0509976B1 (pt)	2020-10-06
EP1588704A1 (en)	2005-10-26
NZ550664A (en)	2010-08-27
SI1737438T1 (sl)	2008-12-31
EP1737438B1 (en)	2008-08-20

Publication	Publication Date	Title
PL1737438T3 (pl)	2009-01-30	Pochodne Alfa-aminoamidu użyteczne do leczenia zespołu niespokojnych nóg
LTPA2021516I1 (pl)	2021-08-10
IL185016A0 (en)	2007-12-03	Compounds for the treatment of proliferative disorders
IL179508A0 (en)	2007-05-15	2-substituted-4- heteroaryl-pyrimidines useful for the treatment of proliferative disorders
ZA200706691B (en)	2008-09-25	Process for preparing lansoprazole
IL187168A0 (en)	2008-02-09	Improved nanobodiestm for the treatment of aggregation-mediated disorders
EP1853539A4 (en)	2010-04-21	HONOKIOL DERIVATIVES TO TREAT PROLIFERATIVE DISEASES
UA89812C2 (ru)	2010-03-10	Замещенные пиридинильные и пиримидинильные производные, которые применяют как модуляторы метаболизма и для лечения ассоциированных с ним расстройств
ZA200903952B (en)	2010-11-24	Bicyclic compounds and use as antidiabetics
ZA200700384B (en)	2008-09-25	Hydantoin derivatives for the treatment of inflammatory disorders
ZA200700011B (en)	2008-11-26	Pyrrolotriazine derivatives useful for treating hyper-proliferative disorders diseases associated with angiogenesis
IL188390A0 (en)	2008-04-13	Imidazolyl-pyrimidine compounds for use in the treatment of proliferative disorders
MY147649A (en)	2012-12-31	Benzimidazole derivatives useful in treatment of vallinoid receptor trpv1 related disorders
WO2008011113A3 (en)	2008-02-28	Thiadiazolidinone derivatives
ZA200805159B (en)	2009-03-25	Imidazole derivatives for the treatment of gastrointestinal disorders
PT2366393E (pt)	2013-10-04	Roflumilaste para o tratamento da hipertensão pulmonar
PL1879585T3 (pl)	2013-08-30	Zastosowanie pochodnych pirymidyloaminobenzamidowych do leczenia mastocytozy układowej
ZA200800409B (en)	2010-03-31	Imidazolyl-pyrimidine compounds for use in the treatment of proliferative disorders
EP1937242A4 (en)	2011-06-15	METHOD AND COMPOSITIONS FOR THE TREATMENT OF NEUROPSYCHIATRIC DISEASES AND ADDITIVES
PL1961423T3 (pl)	2012-09-28	Zastosowanie pneumocytów typu II w leczeniu chorób płuc związanych z zwłóknieniem płuc
HK1118542A (en)	2009-02-13	Imidazolyl-pyrimidine compounds for use in the treatment of proliferative disorders
IL188104A0 (en)	2008-04-13	Compounds useful for treating bipolar disorders
GB0807094D0 (en)	2008-05-21	4,4-dimethylpiperidine-2, 6-dione derivatives for use in the treatment of hypertension
WO2006060202A3 (en)	2006-12-14	Imidazole derivatives for the treatment of psychiatric disorders