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PL1735349T3 - Sposób oceny ryzyka niedokrwiennego schorzenia układu sercowo-naczyniowego za pomocą koniugatów fosforylocholiny - Google Patents

Sposób oceny ryzyka niedokrwiennego schorzenia układu sercowo-naczyniowego za pomocą koniugatów fosforylocholiny

Info

Publication number
PL1735349T3
PL1735349T3 PL05735991T PL05735991T PL1735349T3 PL 1735349 T3 PL1735349 T3 PL 1735349T3 PL 05735991 T PL05735991 T PL 05735991T PL 05735991 T PL05735991 T PL 05735991T PL 1735349 T3 PL1735349 T3 PL 1735349T3
Authority
PL
Poland
Prior art keywords
assessing
risk
cardiovascular disease
ischemic cardiovascular
phosphorylcholine conjugates
Prior art date
Application number
PL05735991T
Other languages
English (en)
Inventor
Faire Ulf De
Johan Frostegaard
Original Assignee
Athera Biotechnologies Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Athera Biotechnologies Ab filed Critical Athera Biotechnologies Ab
Publication of PL1735349T3 publication Critical patent/PL1735349T3/pl

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39583Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials not provided for elsewhere, e.g. haptens, coenzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/646Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/32Cardiovascular disorders
    • G01N2800/323Arteriosclerosis, Stenosis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/50Determining the risk of developing a disease
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Mycology (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Peptides Or Proteins (AREA)
PL05735991T 2004-04-15 2005-04-15 Sposób oceny ryzyka niedokrwiennego schorzenia układu sercowo-naczyniowego za pomocą koniugatów fosforylocholiny PL1735349T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US52138404P 2004-04-15 2004-04-15
EP05735991A EP1735349B1 (en) 2004-04-15 2005-04-15 Method of assessing the risk of ischemic cardiovascular disease using phosphorylcholine conjugates
PCT/GB2005/001463 WO2005100405A2 (en) 2004-04-15 2005-04-15 Phosphorylcholine conjugates and corresponding antibodies

Publications (1)

Publication Number Publication Date
PL1735349T3 true PL1735349T3 (pl) 2011-03-31

Family

ID=34981497

Family Applications (2)

Application Number Title Priority Date Filing Date
PL06077208T PL1797893T3 (pl) 2004-04-15 2005-04-15 Przeciwciała przeciwko koniugatom fosforylocholiny
PL05735991T PL1735349T3 (pl) 2004-04-15 2005-04-15 Sposób oceny ryzyka niedokrwiennego schorzenia układu sercowo-naczyniowego za pomocą koniugatów fosforylocholiny

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL06077208T PL1797893T3 (pl) 2004-04-15 2005-04-15 Przeciwciała przeciwko koniugatom fosforylocholiny

Country Status (15)

Country Link
US (4) US8012483B2 (pl)
EP (3) EP2258728A1 (pl)
JP (2) JP4891228B2 (pl)
CN (4) CN105699669A (pl)
AT (2) ATE480778T1 (pl)
AU (2) AU2005233361B2 (pl)
CA (2) CA2562550C (pl)
CY (2) CY1110188T1 (pl)
DE (2) DE602005023428D1 (pl)
DK (2) DK1735349T3 (pl)
ES (2) ES2362222T3 (pl)
PL (2) PL1797893T3 (pl)
PT (2) PT1735349E (pl)
SI (2) SI1735349T1 (pl)
WO (1) WO2005100405A2 (pl)

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EP1827111A4 (en) 2004-12-22 2015-07-22 Avon Prod Inc METHOD AND COMPOSITION FOR REDUCING THE APPEARANCE OF WRINKLES
NZ561218A (en) * 2005-02-07 2011-04-29 Univ California Methods for reducing the symptoms of autoimmunity and inflammation using binding proteins against antigens exposed on dead or dying cells
US7745146B2 (en) * 2006-07-26 2010-06-29 Inova Diagnostics, Inc. Compositions and methods for diagnosing patients with acute atherosclerotic syndrome
MX2009006744A (es) * 2006-12-22 2009-06-30 Abbott Lab Panel de padecimiento cardiovascular autoinmune y metodos de utilizacion del mismo.
AU2008320650A1 (en) * 2007-10-30 2009-05-07 Athera Biotechnologies Ab Diagnostic and therapeutic methods and compositions for cardiovascular disease
CN102124342A (zh) 2008-07-07 2011-07-13 阿瑟拉生物技术公司 阿尔茨海默病新的治疗和诊断方法
CU23736A1 (es) 2009-05-04 2011-11-15 Centro Inmunologia Molecular Anticuerpos que reconocen sulfatidos y proteoglicanos sulfatados y su uso
EP2542580B1 (en) * 2010-03-04 2021-08-04 Athera Biotechnologies AB Antibodies against phosphorylcholine in combination therapy with biologic agents
WO2012010291A1 (en) 2010-07-21 2012-01-26 Athera Biotechnologies Ab Diagnostic and therapeutic methods and compositions for metabolic disease
JP5904553B2 (ja) * 2010-11-17 2016-04-13 国立大学法人愛媛大学 自己免疫疾患に関与するタンパク質の解析方法及び該疾患の検査方法
EP2741770A4 (en) * 2011-08-09 2014-12-31 Athera Biotechnologies Ab ANTIBODY BINDING TO PHOSPHORYLCHOLIN (PC) AND / OR PC CONJUGATES
EP2742068B1 (en) * 2011-08-09 2019-04-03 Athera Biotechnologies AB New antibodies against phosphorylcholine
EP2953978B1 (en) 2013-02-05 2024-10-23 Tpcera Ltd. Phosphorylcholine conjugates and uses thereof
US10046021B2 (en) 2013-02-05 2018-08-14 Tpcera Ltd. Phosphorylcholine conjugates and uses thereof
US10500260B2 (en) * 2014-02-04 2019-12-10 3Dt Holdings, Llc Substances, vaccines and methods for diagnosing and reducing incidences of transplant rejection
US11065319B2 (en) * 2014-02-04 2021-07-20 3Dt Holdings, Llc Methods for diagnosing and reducing incidences of cardiac allograft rejection
JP6547755B2 (ja) 2014-10-15 2019-07-24 日油株式会社 ホスホリルコリン基含有化合物およびホスホリルコリン複合体
CN105175504A (zh) * 2015-09-08 2015-12-23 苏州普罗达生物科技有限公司 血管性血友病因子抑制多肽及其应用
WO2018220224A1 (en) * 2017-06-02 2018-12-06 Medirista Biotechnologies Ab Lipid-related antigens and antibodies directed against them
AU2021251423A1 (en) * 2020-04-10 2022-10-27 Vanudis GmbH Natural antibodies in prophylaxis and therapy
GB2622559A (en) * 2022-05-10 2024-03-27 Johan Frostegaard Compositions, methods and uses
WO2024028192A1 (de) 2022-08-04 2024-02-08 Pentracor Gmbh Verwendung von phosphocholin-humanserumalbumin-konjugaten zur blockade von c-reaktivem protein
AU2024240129A1 (en) 2023-03-17 2025-10-09 Oxitope Pharma B.V. Anti-phosphocholine antibodies and methods of use thereof

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Also Published As

Publication number Publication date
AU2005233361B2 (en) 2011-02-24
CA2562550A1 (en) 2005-10-27
EP1735349B1 (en) 2010-09-08
WO2005100405A3 (en) 2006-04-13
JP2008501636A (ja) 2008-01-24
CN105699669A (zh) 2016-06-22
US20120039895A1 (en) 2012-02-16
US20160131661A1 (en) 2016-05-12
CN1968965A (zh) 2007-05-23
AU2005233361A1 (en) 2005-10-27
ES2357606T3 (es) 2011-04-28
CN103743898B (zh) 2019-02-05
CY1111659T1 (el) 2015-10-07
EP1797893B1 (en) 2010-04-07
PT1797893E (pt) 2010-07-14
CA2562550C (en) 2013-09-24
US20070286868A1 (en) 2007-12-13
SI1797893T1 (sl) 2010-08-31
DK1735349T3 (da) 2010-12-06
EP1797893A3 (en) 2007-06-27
DK1797893T3 (da) 2010-08-02
CA2776927A1 (en) 2005-10-27
ATE463254T1 (de) 2010-04-15
DE602005020474D1 (de) 2010-05-20
SI1735349T1 (sl) 2010-12-31
AU2011202334B2 (en) 2012-12-06
WO2005100405A2 (en) 2005-10-27
JP4891228B2 (ja) 2012-03-07
CY1110188T1 (el) 2015-01-14
EP1797893A2 (en) 2007-06-20
ES2362222T3 (es) 2011-06-29
CN1968965B (zh) 2015-12-16
PT1735349E (pt) 2010-12-14
PL1797893T3 (pl) 2010-09-30
CA2776927C (en) 2014-08-12
ATE480778T1 (de) 2010-09-15
US20140186360A1 (en) 2014-07-03
DE602005023428D1 (de) 2010-10-21
US10222382B2 (en) 2019-03-05
EP2258728A1 (en) 2010-12-08
EP1735349A2 (en) 2006-12-27
CN103908669A (zh) 2014-07-09
CN103743898A (zh) 2014-04-23
CN103908669B (zh) 2017-07-04
JP5366987B2 (ja) 2013-12-11
JP2011099871A (ja) 2011-05-19
US8012483B2 (en) 2011-09-06
AU2011202334A1 (en) 2011-06-09

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