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PL1767526T3 - Pochodna aryloamidydyny, jej sól oraz zawierający je środek przeciwgrzybiczny - Google Patents

Pochodna aryloamidydyny, jej sól oraz zawierający je środek przeciwgrzybiczny

Info

Publication number
PL1767526T3
PL1767526T3 PL05765373T PL05765373T PL1767526T3 PL 1767526 T3 PL1767526 T3 PL 1767526T3 PL 05765373 T PL05765373 T PL 05765373T PL 05765373 T PL05765373 T PL 05765373T PL 1767526 T3 PL1767526 T3 PL 1767526T3
Authority
PL
Poland
Prior art keywords
salt
arylamidine derivative
antifungal containing
antifungal
arylamidine
Prior art date
Application number
PL05765373T
Other languages
English (en)
Inventor
Kazuya Hayashi
Kazuto Kunitani
Sayuri Uehara
Teiichi Morita
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Publication of PL1767526T3 publication Critical patent/PL1767526T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C257/00Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
    • C07C257/10Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
    • C07C257/18Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to carbon atoms of six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Saccharide Compounds (AREA)
PL05765373T 2004-06-30 2005-06-28 Pochodna aryloamidydyny, jej sól oraz zawierający je środek przeciwgrzybiczny PL1767526T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2004193386 2004-06-30
PCT/JP2005/011809 WO2006003881A1 (ja) 2004-06-30 2005-06-28 新規なアリールアミジン誘導体およびその塩ならびにそれらを含有する抗真菌剤
EP05765373A EP1767526B1 (en) 2004-06-30 2005-06-28 Arylamidine derivative, salt thereof and antifungal containing these

Publications (1)

Publication Number Publication Date
PL1767526T3 true PL1767526T3 (pl) 2013-03-29

Family

ID=35782688

Family Applications (1)

Application Number Title Priority Date Filing Date
PL05765373T PL1767526T3 (pl) 2004-06-30 2005-06-28 Pochodna aryloamidydyny, jej sól oraz zawierający je środek przeciwgrzybiczny

Country Status (20)

Country Link
US (1) US7700623B2 (pl)
EP (1) EP1767526B1 (pl)
JP (1) JP4885722B2 (pl)
KR (1) KR101169694B1 (pl)
CN (1) CN100567267C (pl)
AU (1) AU2005258613B2 (pl)
BR (1) BRPI0512661B8 (pl)
CA (1) CA2572161C (pl)
CY (1) CY1113266T1 (pl)
DK (1) DK1767526T3 (pl)
ES (1) ES2393924T3 (pl)
IL (1) IL180192A (pl)
NO (1) NO339158B1 (pl)
NZ (1) NZ552184A (pl)
PL (1) PL1767526T3 (pl)
PT (1) PT1767526E (pl)
RU (1) RU2359959C2 (pl)
SI (1) SI1767526T1 (pl)
WO (1) WO2006003881A1 (pl)
ZA (1) ZA200700806B (pl)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ561675A (en) * 2005-04-07 2010-07-30 Toyama Chemical Co Ltd Pharmaceutical composition and method using antifungal agent in combination
JP2008545009A (ja) * 2005-06-30 2008-12-11 プロシディオン・リミテッド Gpcrアゴニスト
TWI385169B (zh) 2005-10-31 2013-02-11 Eisai R&D Man Co Ltd 經雜環取代之吡啶衍生物及含有彼之抗真菌劑
PT1967190E (pt) 2005-12-29 2010-10-14 Toyama Chemical Co Ltd Novos derivados de arilamidina, os seus sais e agentes antifúngicos que os contêm
PL2070536T3 (pl) 2006-10-06 2012-06-29 Toyama Chemical Co Ltd Kompozycja farmaceutyczna zawierająca pochodną fenyloamidyny oraz sposób stosowania kompozycji farmaceutycznej w kombinacji ze środkiem przeciwgrzybiczym
TW200841879A (en) 2007-04-27 2008-11-01 Eisai R&D Man Co Ltd Pyridine derivatives substituted by heterocyclic ring and phosphonoamino group, and anti-fungal agent containing same
TWI395735B (zh) * 2007-07-04 2013-05-11 Toyama Chemical Co Ltd 4-{3-〔4-(3-{4-〔胺基(丁氧基羰基亞胺基)甲基〕苯氧基}丙基)-1-哌啶基〕丙氧基}-n’-(丁氧基羰基)苄脒之新穎結晶
DE102008007440A1 (de) * 2008-02-01 2009-08-13 Dritte Patentportfolio Beteiligungsgesellschaft Mbh & Co.Kg Aminosäurederivate als Arzneistoffe
DE102008007381A1 (de) 2008-02-01 2009-08-13 Dritte Patentportfolio Beteiligungsgesellschaft Mbh & Co.Kg Amidine und Guanidine und deren Derivate zur Behandlung von Krankheiten
AU2014200451B2 (en) * 2008-02-01 2016-03-03 Dritte Patentportfolio Beteiligungsgesellschaft Mbh & Co. Kg Use of amidoxime carboxylic acid esters and n-hydroxyguanidine carboxylic acid esters for producing prodrugs
US9662308B2 (en) * 2008-02-01 2017-05-30 Dritte Patentportfolio Beteiligungsgesellschaft Mbh & Co. Kg Orally bioavailable pentamidine prodrugs for the treatment of diseases
WO2011104540A1 (en) * 2010-02-24 2011-09-01 Generics [Uk] Limited One step process for the preparation of capecitabine
JP5827954B2 (ja) * 2010-09-30 2015-12-02 富山化学工業株式会社 経皮吸収製剤
JPWO2012060448A1 (ja) 2010-11-05 2014-05-12 エーザイ・アール・アンド・ディー・マネジメント株式会社 抗真菌剤としての併用医薬組成物
IL292712A (en) * 2019-11-04 2022-07-01 Appili Therapeutics Inc Composition and method for treating candida auris infection

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL340658A1 (en) * 1997-11-20 2001-02-12 Teijin Ltd Derivatives of biphenylamidine
KR100915979B1 (ko) * 2002-03-06 2009-09-10 토야마 케미칼 컴퍼니 리미티드 신규의 아릴아미딘 유도체 또는 그 염

Also Published As

Publication number Publication date
AU2005258613B2 (en) 2011-03-17
BRPI0512661A (pt) 2008-04-01
KR20070030305A (ko) 2007-03-15
IL180192A0 (en) 2007-06-03
CA2572161C (en) 2012-10-02
EP1767526A1 (en) 2007-03-28
JPWO2006003881A1 (ja) 2008-04-17
NZ552184A (en) 2009-11-27
CN100567267C (zh) 2009-12-09
RU2007103176A (ru) 2008-08-10
ES2393924T3 (es) 2013-01-02
SI1767526T1 (sl) 2013-02-28
CY1113266T1 (el) 2016-04-13
CN1976901A (zh) 2007-06-06
DK1767526T3 (da) 2012-11-12
JP4885722B2 (ja) 2012-02-29
ZA200700806B (en) 2008-12-31
NO339158B1 (no) 2016-11-14
US20080319016A1 (en) 2008-12-25
US7700623B2 (en) 2010-04-20
AU2005258613A1 (en) 2006-01-12
IL180192A (en) 2011-01-31
RU2359959C2 (ru) 2009-06-27
PT1767526E (pt) 2012-12-10
BRPI0512661B1 (pt) 2020-10-27
WO2006003881A1 (ja) 2006-01-12
CA2572161A1 (en) 2006-01-12
NO20070455L (no) 2007-01-24
KR101169694B1 (ko) 2012-07-31
BRPI0512661B8 (pt) 2021-05-25
EP1767526B1 (en) 2012-10-24
EP1767526A4 (en) 2009-05-06

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