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PL1753427T3 - Zastosowanie podstawionych pochodnych chinoliny do leczenia chorób wywoływanych przez prątki lekooporne - Google Patents

Zastosowanie podstawionych pochodnych chinoliny do leczenia chorób wywoływanych przez prątki lekooporne

Info

Publication number
PL1753427T3
PL1753427T3 PL05743054T PL05743054T PL1753427T3 PL 1753427 T3 PL1753427 T3 PL 1753427T3 PL 05743054 T PL05743054 T PL 05743054T PL 05743054 T PL05743054 T PL 05743054T PL 1753427 T3 PL1753427 T3 PL 1753427T3
Authority
PL
Poland
Prior art keywords
treatment
drug resistant
quinoline derivatives
substituted quinoline
mycobacterial diseases
Prior art date
Application number
PL05743054T
Other languages
English (en)
Inventor
Koenraad Jozef Lodewijk Marcel Andries
Gestel Jozef Frans Elisabetha Van
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34929150&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL1753427(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of PL1753427T3 publication Critical patent/PL1753427T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/06Antibacterial agents for tuberculosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL05743054T 2004-05-28 2005-05-24 Zastosowanie podstawionych pochodnych chinoliny do leczenia chorób wywoływanych przez prątki lekooporne PL1753427T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP04102402 2004-05-28
PCT/EP2005/052371 WO2005117875A1 (en) 2004-05-28 2005-05-24 Use of substituted quinoline derivatives for the treatment of drug resistant mycobacterial diseases
EP05743054A EP1753427B1 (en) 2004-05-28 2005-05-24 Use of substituted quinoline derivatives for the treatment of drug resistant mycobacterial diseases

Publications (1)

Publication Number Publication Date
PL1753427T3 true PL1753427T3 (pl) 2008-09-30

Family

ID=34929150

Family Applications (1)

Application Number Title Priority Date Filing Date
PL05743054T PL1753427T3 (pl) 2004-05-28 2005-05-24 Zastosowanie podstawionych pochodnych chinoliny do leczenia chorób wywoływanych przez prątki lekooporne

Country Status (34)

Country Link
US (2) US20070249667A1 (pl)
EP (1) EP1753427B1 (pl)
JP (2) JP5081617B2 (pl)
KR (2) KR20130024969A (pl)
CN (2) CN1976704B (pl)
AP (1) AP2037A (pl)
AR (1) AR049127A1 (pl)
AT (1) ATE390925T1 (pl)
AU (1) AU2005249231B2 (pl)
BR (1) BRPI0510414B1 (pl)
CA (1) CA2566544C (pl)
CL (1) CL2009001980A1 (pl)
CY (1) CY1110388T1 (pl)
DE (1) DE602005005810T2 (pl)
DK (1) DK1753427T3 (pl)
EA (1) EA010651B1 (pl)
ES (1) ES2306146T3 (pl)
HR (1) HRP20080307T3 (pl)
IL (1) IL179630A (pl)
JO (1) JO2524B1 (pl)
ME (1) ME01105B (pl)
MX (1) MXPA06013888A (pl)
MY (1) MY140611A (pl)
NO (1) NO338624B1 (pl)
NZ (1) NZ550840A (pl)
PA (1) PA8635201A1 (pl)
PL (1) PL1753427T3 (pl)
PT (1) PT1753427E (pl)
RS (1) RS50585B (pl)
SI (1) SI1753427T1 (pl)
TW (1) TWI363625B (pl)
UA (1) UA90267C2 (pl)
WO (1) WO2005117875A1 (pl)
ZA (1) ZA200609899B (pl)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
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EP1753427B1 (en) * 2004-05-28 2008-04-02 Janssen Pharmaceutica N.V. Use of substituted quinoline derivatives for the treatment of drug resistant mycobacterial diseases
JP2006182755A (ja) * 2004-12-24 2006-07-13 Janssen Pharmaceut Nv 潜伏性結核の処置
EE05697B1 (et) * 2005-06-08 2014-02-17 Janssen Pharmaceutica N.V. Kinoliini derivaadid kui antibakteriaalsed toimeained
JP5349730B2 (ja) * 2005-06-09 2013-11-20 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 抗バクテリア剤としてのキノリン誘導体
JO3270B1 (ar) * 2005-06-28 2018-09-16 Janssen Pharmaceutica Nv مشتقات كوينولين بصفة عوامل مضادة للبكتيريا
JO2752B1 (en) * 2005-06-28 2014-03-15 شركة جانسين فارماسوتيكا ان. في Quinoline derivatives acting as antibacterial agents
DK1898909T3 (en) * 2005-06-28 2017-02-06 Janssen Pharmaceutica Nv QUINOLIN DERIVATIVES AS ANTIBACTERIAL AGENTS
US8686002B2 (en) 2005-08-21 2014-04-01 AbbVie Deutschland GmbH & Co. KG Heterocyclic compounds and their use as binding partners for 5-HT5 receptors
UA97813C2 (uk) * 2006-12-05 2012-03-26 Янссен Фармацевтика Н.В. Фумаратна сіль (альфа s, бета r)-6-бром-альфа-[2-(диметиламіно)етил]-2-метоксі-альфа-1-нафталеніл-бета-феніл-3-хінолінетанолу
JO2683B1 (en) * 2006-12-06 2013-03-03 جانسين فارماسوتيكا ان. في Quinoline antibacterial derivatives
JO2685B1 (en) * 2006-12-06 2013-03-03 جانسين فارماسوتيكا ان في Quinoline antibacterial derivatives
JO2725B1 (en) * 2006-12-06 2013-09-15 جانسين فارماسوتيكا ان. في Quinoline antibacterial derivatives
JO2970B1 (en) 2006-12-06 2016-03-15 جانسين فارماسوتيكا ان. في Quinoline antibacterial derivatives
JO3271B1 (ar) * 2006-12-06 2018-09-16 Janssen Pharmaceutica Nv مشتقات الكوينولين المضادة للجراثيم
JO2684B1 (en) * 2006-12-06 2013-03-03 جانسين فارماسوتيكا ان في Quinoline antibacterial derivatives
MD4009C2 (ro) * 2008-07-15 2010-08-31 Институт Химии Академии Наук Молдовы Utilizarea 1-metil-4-(N-metilaminobutil-4)-β-carbolinei în calitate de remediu antituberculos
RU2404971C2 (ru) * 2008-12-02 2010-11-27 ЗАО "Фарм-Синтез" Новые производные хинолина, способ их получения, их применение для лечения микобактериальных инфекций, фармацевтическая композиция на их основе
JP2013504591A (ja) * 2009-09-11 2013-02-07 バーテックス ファーマシューティカルズ インコーポレイテッド N−ベンジル−3−(4−クロロフェニル)−2−[メチル−[2−オキソ−2−(3,4,5−トリメトキシフェニル)アセチル]アミノ]−n−[3−(4−ピリジル)−1−[2−(4−ピリジル)エチル]プロピル]プロパンアミドの組成物およびその使用
CN102249935B (zh) 2010-05-17 2015-05-20 中国人民解放军军事医学科学院毒物药物研究所 芳香2-丁醇类化合物及其医药用途
CN104254527B (zh) 2012-04-27 2017-05-31 詹森药业有限公司 抗菌的喹啉衍生物
AU2013254670B2 (en) 2012-04-27 2017-03-30 Janssen Pharmaceutica Nv Antibacterial quinoline derivatives
WO2016008381A1 (zh) * 2014-07-14 2016-01-21 辰欣药业股份有限公司 吡啶衍生物及其作为抗分支杆菌的应用
CN105330595B (zh) * 2014-07-14 2019-12-10 上海嘉坦医药科技有限公司 吡啶衍生物及其作为抗分支杆菌的应用
FI3250182T3 (fi) 2015-01-27 2023-06-28 Janssen Pharmaceutica Nv Dispergoituvia koostumuksia
CN106279017A (zh) * 2015-05-21 2017-01-04 重庆圣华曦药业股份有限公司 贝达喹啉晶型、组合物及其制备方法
RU2018111482A (ru) * 2015-10-20 2019-11-21 Чжэцзян Хисунь Фармасьютикал Ко., Лтд. Кристаллические формы бедаквилин фумарата и способы их получения
WO2017121323A1 (zh) * 2016-01-13 2017-07-20 辰欣药业股份有限公司 一种吡啶衍生物类化合物的制备方法及其中间体和晶型
CA3016068C (en) * 2016-03-07 2024-02-27 The Global Alliance For Tb Drug Development, Inc. Antibacterial compounds and uses thereof
CN107243008B (zh) * 2017-04-13 2021-03-30 中国科学院广州生物医药与健康研究院 吡唑并[1,5-a]吡啶类化合物的新应用及一种治疗脓肿分枝杆菌感染的组合物
JP7184260B2 (ja) * 2017-09-01 2022-12-06 学校法人北里研究所 マイコバクテリウム・アビウム複合感染症に対する治療活性を有する新規化合物及びその製造方法
WO2020047596A1 (en) * 2018-09-04 2020-03-12 Monash University Antibacterial compounds and methods of use
WO2020144197A1 (en) 2019-01-09 2020-07-16 Janssen Pharmaceutica Nv Combination in the treatment of nontuberculous mycobacterial diseases
US20230348436A1 (en) * 2019-11-26 2023-11-02 Nanyang Technological University Compounds for treating tuberculosis
CN110804016B (zh) * 2019-12-05 2022-11-04 福建省微生物研究所 抗结核分枝杆菌的二芳基喹啉衍生物
KR20230107275A (ko) 2020-11-12 2023-07-14 얀센 파마슈티카 엔.브이. 비결핵성 마이코박테리아 질환의 치료에서 베다퀼린, 에탐부톨 및 마크롤라이드의 조합물
WO2023217279A1 (zh) * 2022-05-13 2023-11-16 广州嘉越医药科技有限公司 一种吡啶衍生物、中间体、制备方法和应用
WO2023227123A1 (zh) * 2022-05-27 2023-11-30 广州嘉越医药科技有限公司 吡啶衍生物的用途
WO2023232838A1 (en) 2022-05-31 2023-12-07 Janssen Pharmaceutica Nv Bedaquiline for use in the treatment of leprosy
CN120225518A (zh) * 2022-11-15 2025-06-27 伊莱利利公司 Ahr激动剂
WO2025068448A1 (en) 2023-09-28 2025-04-03 Janssen Pharmaceutica Nv Atp synthase inhibitors for use in the treatment of non-tuberculosis mycobacteria

Family Cites Families (6)

* Cited by examiner, † Cited by third party
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US5399558A (en) * 1993-11-24 1995-03-21 Pathogenesis Corporation Isoflavonoid antibacterial compounds, compositions and use
WO1998018326A1 (en) * 1996-10-28 1998-05-07 Department Of The Army, U.S. Government Compounds, compositions and methods for treating antibiotic-resistant infections
US6103905A (en) * 1997-06-19 2000-08-15 Sepracor, Inc. Quinoline-indole antimicrobial agents, uses and compositions related thereto
DK2301544T3 (da) * 2002-07-25 2013-01-02 Janssen Pharmaceutica Nv Quinolinderivater som mellemprodukter til mykobakterielle inhibitorer
EP1753427B1 (en) * 2004-05-28 2008-04-02 Janssen Pharmaceutica N.V. Use of substituted quinoline derivatives for the treatment of drug resistant mycobacterial diseases
EE05697B1 (et) * 2005-06-08 2014-02-17 Janssen Pharmaceutica N.V. Kinoliini derivaadid kui antibakteriaalsed toimeained

Also Published As

Publication number Publication date
CN102908347A (zh) 2013-02-06
KR101371653B1 (ko) 2014-03-07
HK1106136A1 (en) 2008-03-07
AU2005249231B2 (en) 2010-11-11
ZA200609899B (en) 2009-01-28
CN1976704B (zh) 2012-12-05
NO338624B1 (no) 2016-09-19
DE602005005810D1 (de) 2008-05-15
KR20130024969A (ko) 2013-03-08
AR049127A1 (es) 2006-06-28
CY1110388T1 (el) 2015-04-29
KR20070017393A (ko) 2007-02-09
BRPI0510414B1 (pt) 2022-04-05
EP1753427A1 (en) 2007-02-21
CN1976704A (zh) 2007-06-06
CA2566544A1 (en) 2005-12-15
NZ550840A (en) 2010-01-29
BRPI0510414A (pt) 2007-10-23
AP2006003828A0 (en) 2006-12-31
PT1753427E (pt) 2008-07-04
EP1753427B1 (en) 2008-04-02
DK1753427T3 (da) 2008-07-21
HRP20080307T3 (hr) 2008-07-31
RS50585B (sr) 2010-05-07
WO2005117875A1 (en) 2005-12-15
PA8635201A1 (es) 2006-05-16
US20070249667A1 (en) 2007-10-25
TWI363625B (en) 2012-05-11
JP2008500992A (ja) 2008-01-17
TW200608974A (en) 2006-03-16
ME01105B (me) 2013-03-20
US20100168133A1 (en) 2010-07-01
MY140611A (en) 2009-12-31
CL2009001980A1 (es) 2010-04-16
CA2566544C (en) 2012-04-17
JO2524B1 (en) 2010-03-17
JP5081617B2 (ja) 2012-11-28
AU2005249231A1 (en) 2005-12-15
ES2306146T3 (es) 2008-11-01
IL179630A (en) 2011-05-31
EA200602260A1 (ru) 2007-04-27
EA010651B1 (ru) 2008-10-30
UA90267C2 (ru) 2010-04-26
ATE390925T1 (de) 2008-04-15
SI1753427T1 (sl) 2008-10-31
AP2037A (en) 2009-10-09
MXPA06013888A (es) 2007-01-26
DE602005005810T2 (de) 2009-04-09
JP2012229239A (ja) 2012-11-22
NO20066041L (no) 2007-02-27
JP5675718B2 (ja) 2015-02-25
IL179630A0 (en) 2007-07-04

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