PL1603917T3 - Związki heterocykliczne o właściwościach immunomodulujących - Google Patents

Związki heterocykliczne o właściwościach immunomodulujących

Info

Publication number: PL1603917T3
Authority: PL; Poland
Prior art keywords: heterocyclic compounds; immunomodulating; immunomodulating heterocyclic; solvate; hydrate
Prior art date: 2003-03-14

Application number

PL04719006T

Other languages

English (en)

Inventor

Ian Richard Mathews

Original Assignee

Medigene Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-03-14

Filing date

2004-03-10

Publication date

2011-12-30

2003-03-14 Priority claimed from GB0305876A external-priority patent/GB0305876D0/en

2003-08-19 Priority claimed from GB0319429A external-priority patent/GB0319429D0/en

2004-03-10 Application filed by Medigene Ag filed Critical Medigene Ag

2011-12-30 Publication of PL1603917T3 publication Critical patent/PL1603917T3/pl

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Immunology (AREA)
Diabetes (AREA)
Pulmonology (AREA)
Physical Education & Sports Medicine (AREA)
Endocrinology (AREA)
Rheumatology (AREA)
Hematology (AREA)
Obesity (AREA)
Dermatology (AREA)
Surgery (AREA)
Pain & Pain Management (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Emergency Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Transplantation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

PL04719006T 2003-03-14 2004-03-10 Związki heterocykliczne o właściwościach immunomodulujących PL1603917T3 (pl)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
GB0305876A GB0305876D0 (en)	2003-03-14	2003-03-14	Immuno inhibitory heterocyclic compounds
GB0319429A GB0319429D0 (en)	2003-08-19	2003-08-19	Immuno Inhibitory Heterocyclic compounds
EP04719006A EP1603917B1 (en)	2003-03-14	2004-03-10	Immunomodulating heterocyclic compounds
PCT/GB2004/001008 WO2004081011A1 (en)	2003-03-14	2004-03-10	Immunomodulating heterocyclic compounds

Publications (1)

Publication Number	Publication Date
PL1603917T3 true PL1603917T3 (pl)	2011-12-30

Family

ID=32992598

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
PL383655A PL383655A1 (pl)	2003-03-14	2004-03-10	Związki heterocykliczne regulujące układ odpornościowy
PL04719006T PL1603917T3 (pl)	2003-03-14	2004-03-10	Związki heterocykliczne o właściwościach immunomodulujących

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
PL383655A PL383655A1 (pl)	2003-03-14	2004-03-10	Związki heterocykliczne regulujące układ odpornościowy

Country Status (19)

Country	Link
US (3)	US7276505B2 (pl)
EP (2)	EP2284172A1 (pl)
JP (1)	JP4892338B2 (pl)
KR (1)	KR101133959B1 (pl)
AT (1)	ATE489388T1 (pl)
BR (1)	BRPI0408365B8 (pl)
CA (1)	CA2519063C (pl)
DE (1)	DE602004030225D1 (pl)
DK (1)	DK1603917T3 (pl)
EA (2)	EA014080B1 (pl)
EC (1)	ECSP056104A (pl)
IL (1)	IL170389A (pl)
MX (1)	MXPA05009667A (pl)
NO (1)	NO332136B1 (pl)
NZ (1)	NZ541973A (pl)
PL (2)	PL383655A1 (pl)
PT (1)	PT1603917E (pl)
SI (1)	SI1603917T1 (pl)
WO (1)	WO2004081011A1 (pl)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK1603917T3 (da)	2003-03-14	2011-02-28	Medigene Ag	Immunmodulerende heterocycliske forbindelser
GB0325644D0 (en)	2003-11-04	2003-12-10	Avidex Ltd	Immuno ihibitory pyrazolone compounds
GB0411770D0 (en) *	2004-05-26	2004-06-30	Avidex Ltd	Immuno inhibitory heterocyclic compouds
US7932253B2 (en)	2004-08-09	2011-04-26	Medigene Ag	Immunomodulating oxopyrrazolocinnolines as CD80 inhibitors
JP2009504597A (ja) *	2005-08-10	2009-02-05	バイエル・シエーリング・ファーマアクチエンゲゼルシャフト	アシルトリプトファノール
GB0603522D0 (en) *	2006-02-22	2006-04-05	Avidex Ltd	Kinase inhibition
MX2008011791A (es)	2006-03-15	2008-09-25	Wyeth Corp	Azaciclilaminas-n-sustituidas como antagonistas de histamina-3.
MX2008014743A (es)	2006-05-19	2008-12-01	Wyeth Corp	N-benzoil- y n-bencilpirrolidin-3-ilaminas como antagonistas de histamina-3.
JPWO2008004610A1 (ja) *	2006-07-05	2009-12-03	国立大学法人東京大学	ナンセンス変異型遺伝性疾患の治療方法
PE20081152A1 (es)	2006-10-06	2008-08-10	Wyeth Corp	Azaciclilaminas n-sustituidas como antagonistas de histamina-3
PE20090812A1 (es)	2007-07-16	2009-06-14	Wyeth Corp	Derivados de aminoalquilazol como antagonistas de histamina-3
EP2020404A1 (en) *	2007-08-01	2009-02-04	Bayer Schering Pharma Aktiengesellschaft	Cyanomethyl substituted N-Acyl Tryptamines
WO2009043784A1 (en)	2007-10-04	2009-04-09	F. Hoffmann-La Roche Ag	Cyclopropyl aryl amide derivatives and uses thereof
GB201021104D0 (en)	2010-12-13	2011-01-26	Univ Leuven Kath	Novel compounds for the treatment of neurodegenerative diseases
EP2676666A1 (en)	2012-06-20	2013-12-25	Eidgenössische Technische Hochschule Zürich (ETH)	Compounds for use in diagnosis or therapy of vulnerable atherosclerotic plaques
EP2883883A1 (en)	2013-12-16	2015-06-17	Cardio3 Biosciences S.A.	Therapeutic targets and agents useful in treating ischemia reperfusion injury
US20170247326A1 (en) *	2014-09-10	2017-08-31	Epizyme, Inc.	Substituted Pyrrolidine Carboxamide Compounds
US11046683B2 (en)	2016-12-15	2021-06-29	Ono Pharmaceutical Co., Ltd.	Activator of TREK (TWIK RElated K+ channels) channels

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB629412A (en)	1946-12-24	1949-09-20	Geigy Ag J R	Manufacture of metallisable monoazo dyestuffs of the pyrazolone series
US3576637A (en)	1967-04-20	1971-04-27	Konishiroku Photo Ind	Lith-type of emulsion containing pyrozolone
JPS61161285A (ja) *	1984-12-28	1986-07-21	ルセル−ユクラフ	ピラゾロ〔４，３−ｃ〕シンノリン−３−オンの誘導体、それらの塩類、これらの製造法、薬剤としての使用、これらを含有する組成物及び中間体生成物
US4591589A (en) *	1985-01-16	1986-05-27	Roussel Uclaf	2-aryl pyrazolo[4,3-c]cinnolin-3-ones
DE3626221A1 (de)	1986-08-02	1988-02-04	Agfa Gevaert Ag	Farbfotografisches aufzeichnungsmaterial zur herstellung farbiger aufsichtsbilder
US4906644A (en)	1986-11-20	1990-03-06	Mitsubishi Kasei Corporation	Lipid-peroxide formation inhibiting composition and novel compounds useful therefor
DE3903993A1 (de)	1989-02-10	1990-08-16	Basf Ag	Diarylsubstituierte heterocyclische verbindungen, ihre herstellung und arzneimittel daraus
AR006520A1 (es) *	1996-03-20	1999-09-08	Astra Pharma Prod	Derivados de 2-arilpirazolisoquinolina y cinolinona y procedimiento para su preparacion.
GB9713707D0 (en)	1997-06-27	1997-09-03	Merck Sharp & Dohme	Therapeutic agents
SE0102404D0 (sv)	2001-07-04	2001-07-04	Active Biotech Ab	Novel immunomodulating compounds
CA2452596C (en)	2001-07-05	2010-12-21	Takeda Chemical Industries, Ltd.	Benzo-fused 5-membered heterocyclic compounds, their production and use
US7566711B2 (en) *	2001-10-12	2009-07-28	Choongwae Pharma Corporation	Reverse-turn mimetics and method relating thereto
ATE353898T1 (de)	2002-11-22	2007-03-15	Active Biotech Ab	Pyrazolochinoline mit immunmodulierenderwirkung
ATE425164T1 (de)	2002-12-16	2009-03-15	Active Biotech Ab	Tetrazyklische immunmodulierende verbindungen
DK1603917T3 (da)	2003-03-14	2011-02-28	Medigene Ag	Immunmodulerende heterocycliske forbindelser
GB0325644D0 (en)	2003-11-04	2003-12-10	Avidex Ltd	Immuno ihibitory pyrazolone compounds
GB0411770D0 (en)	2004-05-26	2004-06-30	Avidex Ltd	Immuno inhibitory heterocyclic compouds
US7932253B2 (en)	2004-08-09	2011-04-26	Medigene Ag	Immunomodulating oxopyrrazolocinnolines as CD80 inhibitors
US20060221590A1 (en) *	2005-03-31	2006-10-05	Edoardo Campini	System and method for Advanced Mezzanine Card connection
GB0603522D0 (en)	2006-02-22	2006-04-05	Avidex Ltd	Kinase inhibition

2004
- 2004-03-10 DK DK04719006.1T patent/DK1603917T3/da active
- 2004-03-10 BR BRPI0408365A patent/BRPI0408365B8/pt not_active IP Right Cessation
- 2004-03-10 SI SI200431606T patent/SI1603917T1/sl unknown
- 2004-03-10 EP EP10014524A patent/EP2284172A1/en not_active Withdrawn
- 2004-03-10 DE DE602004030225T patent/DE602004030225D1/de not_active Expired - Lifetime
- 2004-03-10 NZ NZ541973A patent/NZ541973A/en not_active IP Right Cessation
- 2004-03-10 JP JP2006505937A patent/JP4892338B2/ja not_active Expired - Lifetime
- 2004-03-10 EA EA200702435A patent/EA014080B1/ru not_active IP Right Cessation
- 2004-03-10 KR KR1020057017070A patent/KR101133959B1/ko not_active Expired - Lifetime
- 2004-03-10 AT AT04719006T patent/ATE489388T1/de active
- 2004-03-10 WO PCT/GB2004/001008 patent/WO2004081011A1/en not_active Ceased
- 2004-03-10 MX MXPA05009667A patent/MXPA05009667A/es active IP Right Grant
- 2004-03-10 CA CA2519063A patent/CA2519063C/en not_active Expired - Lifetime
- 2004-03-10 PL PL383655A patent/PL383655A1/pl unknown
- 2004-03-10 PL PL04719006T patent/PL1603917T3/pl unknown
- 2004-03-10 EP EP04719006A patent/EP1603917B1/en not_active Expired - Lifetime
- 2004-03-10 PT PT04719006T patent/PT1603917E/pt unknown
- 2004-03-10 US US10/547,448 patent/US7276505B2/en not_active Expired - Lifetime
- 2004-03-10 EA EA200501370A patent/EA009680B1/ru not_active IP Right Cessation
2005
- 2005-08-18 IL IL170389A patent/IL170389A/en active IP Right Grant
- 2005-10-13 NO NO20054710A patent/NO332136B1/no unknown
- 2005-10-14 EC EC2005006104A patent/ECSP056104A/es unknown
2007
- 2007-08-28 US US11/845,837 patent/US7598247B2/en not_active Expired - Lifetime
2009
- 2009-08-24 US US12/545,902 patent/US8309552B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
SI1603917T1 (sl)	2011-04-29
EP1603917B1 (en)	2010-11-24
AU2004220310A1 (en)	2004-09-23
US7598247B2 (en)	2009-10-06
CA2519063C (en)	2011-05-10
US20080045527A1 (en)	2008-02-21
DK1603917T3 (da)	2011-02-28
ECSP056104A (es)	2006-03-01
EA014080B1 (ru)	2010-08-30
WO2004081011A1 (en)	2004-09-23
EP2284172A1 (en)	2011-02-16
EP1603917A1 (en)	2005-12-14
KR20050121681A (ko)	2005-12-27
BRPI0408365B8 (pt)	2021-05-25
JP4892338B2 (ja)	2012-03-07
PL383655A1 (pl)	2008-04-14
ATE489388T1 (de)	2010-12-15
US7276505B2 (en)	2007-10-02
BRPI0408365B1 (pt)	2018-11-21
NO20054710D0 (no)	2005-10-13
EA009680B1 (ru)	2008-02-28
NO20054710L (no)	2005-12-13
EA200501370A1 (ru)	2006-08-25
US8309552B2 (en)	2012-11-13
HK1090921A1 (zh)	2007-01-05
NZ541973A (en)	2009-06-26
EA200702435A1 (ru)	2008-06-30
PT1603917E (pt)	2011-02-04
JP2006520372A (ja)	2006-09-07
NO332136B1 (no)	2012-07-02
IL170389A (en)	2013-08-29
US20090312334A1 (en)	2009-12-17
CA2519063A1 (en)	2004-09-23
DE602004030225D1 (de)	2011-01-05
BRPI0408365A (pt)	2006-03-21
US20070021428A1 (en)	2007-01-25
KR101133959B1 (ko)	2012-04-09
MXPA05009667A (es)	2006-01-27

Publication	Publication Date	Title
SI1603917T1 (sl)	2011-04-29	Imunomodulacijske heterociklične spojine
GB0214149D0 (en)	2002-07-31	Chemical compounds
GB2398781B (en)	2005-02-02	Kinase inhibitors
IL165264A0 (en)	2005-12-18	Protein kinase inhibitors
PT1585739E (pt)	2011-05-13	Arilciclopropilacetamidas substitu?das como activadores da glucocinase
NL300927I9 (nl)	2019-02-05	Tivozanib of een zout, solvaat of hydraat ervan, in het bijzonder het hydrochloride-monohydraat
AU2003237955A8 (en)	2004-01-06	Phenyloxyalkanonic acid derivatives as hppar activators
AU2003229953A8 (en)	2003-11-17	Phthalazinone derivatives
TW200732306A (en)	2007-09-01	Pyrimidine derivatives
MXPA05013349A (es)	2006-03-09	Derivados de 2-amino-pirimidina como inhibidores de quinasa raf.
HRP20070430T3 (en)	2007-11-30	(3-oxo-3,4-dihydro-quinoxalin-2-yl-amino)-benzamide derivatives and related compounds as glycogen phosphorylase inhibitors for the treatment of diabetes and obesity
WO2004014913A3 (en)	2004-07-29	Derivatives of 2-trifluormethyl-6-aminopurine as phosphodiesterase 4 inhibitors
WO2005074642A3 (en)	2005-10-27	Chemical compounds
WO2005003087A3 (en)	2005-03-17	Oxazole derivatives as antibacterial agents
WO2003059878A3 (en)	2003-12-04	Thieno (3, 2-b) pyridones as antiviral compounds
GB0215392D0 (en)	2002-08-14	Chemical compounds
WO2004091627A3 (en)	2004-11-25	Heterocyclic substituted 1,4-dihydro-4-oxo-1,8-naphthpyridine analogs
GB0403148D0 (en)	2004-03-17	Chemical compounds
WO2003093247A3 (en)	2003-12-24	Antibacterial agents
DE602004031878D1 (de)	2011-04-28	Immunhemmende pyrazolon-verbindungen
SG149005A1 (en)	2009-01-29	Process for the preparation of thiazolopyrimidines
TW200518748A (en)	2005-06-16	Chemical compounds
WO2005068451A3 (en)	2005-10-13	Methods for the synthesis of dictyostatin and derivatives and analogues thereof, stereochemical characterisation, novel dictyostatin compounds and uses thereof and synthetic intermediates
WO2004103305A3 (en)	2005-03-17	Spiropyrazole compound