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PE96999A1 - 1-(4-carbazoliloxi)-3-[2-(2-metoxifenoxi)etilamino]-2-propanol termodinamicamente estable, proceso para su preparacion y composiciones farmaceuticas que contienen dicho compuesto - Google Patents

1-(4-carbazoliloxi)-3-[2-(2-metoxifenoxi)etilamino]-2-propanol termodinamicamente estable, proceso para su preparacion y composiciones farmaceuticas que contienen dicho compuesto

Info

Publication number
PE96999A1
PE96999A1 PE1998000626A PE00062698A PE96999A1 PE 96999 A1 PE96999 A1 PE 96999A1 PE 1998000626 A PE1998000626 A PE 1998000626A PE 00062698 A PE00062698 A PE 00062698A PE 96999 A1 PE96999 A1 PE 96999A1
Authority
PE
Peru
Prior art keywords
preparation
termodinamicamente
metoxifenoxi
carbazoliloxi
etilamino
Prior art date
Application number
PE1998000626A
Other languages
English (en)
Inventor
Erhard Reinholz
Peter Beyer
Original Assignee
Roche Diagnostics Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics Gmbh filed Critical Roche Diagnostics Gmbh
Publication of PE96999A1 publication Critical patent/PE96999A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

SE REFIERE A UNA FORMA CRISTALINA (FORMA I) TERMODINAMICAMENTE ESTABLE DE CARVEDILOL LIBRE DE FORMAS DE SIMILARES CARACTERISTICAS FISICAS; CARACTERIZADA POR a)SU PATRON DE DIFRACCION DE RAYOS X, b)SU ESPECTRO INFRARROJO, b)SU PUNTO DE FUSION DE 123�C-126�C. TAMBIEN SE REFIERE A UN PROCEDIMIENTO PARA LA PREPARACION Y AISLAMIENTO. EL CARVEDILOL PUEDE SER UTIL PARA LA PROFILAXIS O EL TRATAMIENTO DE ENFERMEDADES CIRCULATORIAS Y CARDIACAS
PE1998000626A 1997-07-22 1998-07-15 1-(4-carbazoliloxi)-3-[2-(2-metoxifenoxi)etilamino]-2-propanol termodinamicamente estable, proceso para su preparacion y composiciones farmaceuticas que contienen dicho compuesto PE96999A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97112491A EP0893440A1 (en) 1997-07-22 1997-07-22 Thermodynamically stable modification of 1-(4-carbazolyloxy)-3-[2-(2-methoxyphenoxy)ethylamino]-2-propanole, process for its preparation and pharmaceutical compositions containing it

Publications (1)

Publication Number Publication Date
PE96999A1 true PE96999A1 (es) 1999-10-12

Family

ID=8227094

Family Applications (1)

Application Number Title Priority Date Filing Date
PE1998000626A PE96999A1 (es) 1997-07-22 1998-07-15 1-(4-carbazoliloxi)-3-[2-(2-metoxifenoxi)etilamino]-2-propanol termodinamicamente estable, proceso para su preparacion y composiciones farmaceuticas que contienen dicho compuesto

Country Status (31)

Country Link
EP (2) EP0893440A1 (es)
JP (1) JP2001510824A (es)
KR (1) KR100336229B1 (es)
CN (1) CN1125047C (es)
AR (1) AR015133A1 (es)
AT (1) ATE236123T1 (es)
AU (1) AU740453B2 (es)
BR (1) BR9810776A (es)
CA (1) CA2296637C (es)
CZ (1) CZ296947B6 (es)
DE (1) DE69812964T2 (es)
DK (1) DK1000027T3 (es)
ES (1) ES2195366T3 (es)
HR (1) HRP980406A2 (es)
HU (1) HUP0003198A3 (es)
IL (1) IL133677A (es)
MA (1) MA26523A1 (es)
MY (1) MY117734A (es)
NO (1) NO313588B1 (es)
NZ (1) NZ502136A (es)
PE (1) PE96999A1 (es)
PL (1) PL191602B1 (es)
PT (1) PT1000027E (es)
RU (1) RU2202542C2 (es)
SI (1) SI1000027T1 (es)
TR (1) TR200000148T2 (es)
TW (1) TW505631B (es)
UY (1) UY25108A1 (es)
WO (1) WO1999005105A1 (es)
YU (1) YU2200A (es)
ZA (1) ZA986475B (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2227206T3 (es) * 2000-04-03 2005-04-01 F. Hoffmann-La Roche Ag Soluciones concentradas de carvedilol.
KR20030017569A (ko) * 2000-06-28 2003-03-03 테바 파마슈티컬 인더스트리즈 리미티드 카르베딜올
EP1655285A1 (en) * 2000-06-28 2006-05-10 Teva Pharmaceutical Industries Ltd. Method for preparation of a crystalline form of carvedilol (form II)
WO2003005970A2 (en) * 2001-07-13 2003-01-23 Smithkline Beecham Corporation Carvedilol polymorph
US20050019399A1 (en) 2001-09-21 2005-01-27 Gina Fischer Controlled release solid dispersions
KR100752549B1 (ko) * 2001-09-28 2007-08-30 에프. 호프만-라 로슈 아게 카르베딜올의 유사다형태
MXPA04006909A (es) 2002-01-15 2005-04-19 Teva Pharma Solidos cristalinos de carvedilol y procesos para su preparacion.
WO2003092622A2 (en) * 2002-04-30 2003-11-13 Sb Pharmco Puerto Rico Inc. Carvedilol monocitrate monohydrate
CA2492060C (en) * 2002-06-27 2011-11-01 Sb Pharmco Puerto Rico Inc. Carvedilol phosphate salts and/or solvates thereof, corresponding compositions, and/or methods of treatment
AU2003251627A1 (en) 2002-06-27 2004-01-19 Sb Pharmco Puerto Rico Inc. Carvedilol hydrobromide
US20040151772A1 (en) 2002-11-08 2004-08-05 Egalet A/S Controlled release carvedilol compositions
DE602004031096D1 (de) 2003-03-26 2011-03-03 Egalet As Morphin-system mit kontrollierter freisetzung
WO2004094378A1 (en) * 2003-04-21 2004-11-04 Matrix Laboratories Ltd Process for the preparation of carvedilol form-ii
SI21616A (sl) * 2003-09-02 2005-04-30 Krka, Tovarna Zdravil, D.D., Novo Mesto Nove kristalne oblike karvedilola
JP2007512372A (ja) * 2003-11-25 2007-05-17 エスビー・ファルムコ・プエルト・リコ・インコーポレイテッド カルベジロール塩、対応する組成物、送達および／または治療方法
US20090005429A1 (en) * 2004-12-09 2009-01-01 Zach System S.P.A. Process for the preparation of carvedilol and its enantiomers
US20070043099A1 (en) * 2005-06-09 2007-02-22 Igor Lifshitz Crystalline forms of carvedilol and processes for their preparation
WO2008002683A2 (en) 2006-06-28 2008-01-03 Teva Pharmaceutical Industries Ltd. Polymorphous forms of carvedilol phosphate
RU2366653C2 (ru) * 2006-07-03 2009-09-10 Ооо "Нанокриохимия" Способ получения рентгеноаморфной модификации карведилола
US20080249317A1 (en) * 2007-04-04 2008-10-09 Apotex Inc. Novel amorphous form of carvedilol phosphate and processes for the preparation thereof
CA2687192C (en) 2007-06-04 2015-11-24 Egalet A/S Controlled release pharmaceutical compositions for prolonged effect
NZ594207A (en) 2009-02-06 2013-03-28 Egalet Ltd Immediate release composition resistant to abuse by intake of alcohol
NZ597283A (en) 2009-06-24 2013-07-26 Egalet Ltd Controlled release formulations

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2815926A1 (de) * 1978-04-13 1979-10-18 Boehringer Mannheim Gmbh Neue carbazolyl-(4)-oxy-propanolamin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE2805404A1 (de) * 1978-02-09 1979-08-16 Merck Patent Gmbh 1-aryloxy-3-nitratoalkylamino-2-propanole und verfahren zu ihrer herstellung
DE3319027A1 (de) * 1983-05-26 1984-11-29 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur herstellung von optisch aktiven carbazol-derivaten, neue r- und s-carbazol-derivate, sowie arzneimittel, die diese verbindungen enthalten

Also Published As

Publication number Publication date
AU8631998A (en) 1999-02-16
EP1000027A1 (en) 2000-05-17
HUP0003198A3 (en) 2002-10-28
TW505631B (en) 2002-10-11
NO313588B1 (no) 2002-10-28
CN1125047C (zh) 2003-10-22
AR015133A1 (es) 2001-04-18
YU2200A (sh) 2002-03-18
IL133677A0 (en) 2001-04-30
EP1000027B1 (en) 2003-04-02
RU2202542C2 (ru) 2003-04-20
DK1000027T3 (da) 2003-07-21
JP2001510824A (ja) 2001-08-07
CZ2000221A3 (cs) 2000-05-17
KR20010022097A (ko) 2001-03-15
HUP0003198A2 (en) 2001-03-28
AU740453B2 (en) 2001-11-01
NO20000301D0 (no) 2000-01-21
WO1999005105A1 (en) 1999-02-04
NZ502136A (en) 2002-05-31
EP0893440A1 (en) 1999-01-27
MA26523A1 (fr) 2004-12-20
BR9810776A (pt) 2000-09-19
CA2296637A1 (en) 1999-02-04
HRP980406A2 (en) 1999-04-30
PT1000027E (pt) 2003-07-31
IL133677A (en) 2004-06-01
DE69812964T2 (de) 2004-03-04
ES2195366T3 (es) 2003-12-01
CN1264366A (zh) 2000-08-23
CA2296637C (en) 2005-11-15
SI1000027T1 (en) 2003-10-31
KR100336229B1 (ko) 2002-05-09
MY117734A (en) 2004-07-31
TR200000148T2 (tr) 2000-07-21
UY25108A1 (es) 2000-12-29
ATE236123T1 (de) 2003-04-15
PL338432A1 (en) 2000-11-06
NO20000301L (no) 2000-01-21
HK1029339A1 (en) 2001-03-30
DE69812964D1 (de) 2003-05-08
ZA986475B (en) 2000-01-21
CZ296947B6 (cs) 2006-08-16
PL191602B1 (pl) 2006-06-30

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