[go: up one dir, main page]

PE36395A1 - Feniltiofenil cicloalquenil hidroxiurea - Google Patents

Feniltiofenil cicloalquenil hidroxiurea

Info

Publication number
PE36395A1
PE36395A1 PE1994256818A PE25681894A PE36395A1 PE 36395 A1 PE36395 A1 PE 36395A1 PE 1994256818 A PE1994256818 A PE 1994256818A PE 25681894 A PE25681894 A PE 25681894A PE 36395 A1 PE36395 A1 PE 36395A1
Authority
PE
Peru
Prior art keywords
hydrogen
phenylthiophenyl
hydroxyurea
cycloalkenyl
halogen
Prior art date
Application number
PE1994256818A
Other languages
English (en)
Inventor
Rodney W Stevens
Akiyoshi Kawai
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PE36395A1 publication Critical patent/PE36395A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/46—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having at least one of the nitrogen atoms, not being part of nitro or nitroso groups, further bound to other hetero atoms
    • C07C323/47—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having at least one of the nitrogen atoms, not being part of nitro or nitroso groups, further bound to other hetero atoms to oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/10—Systems containing only non-condensed rings with a five-membered ring the ring being unsaturated

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE REFIERE A UN COMPUESTO DE FORMULA I DONDE: 1) A y B SON HIDROGENO, HALOGENO, ALQUILO C1-C4 QUE PUEDE SER OPCIONALMENTE SUSTITUIDO POR HALOGENOS, ALCOXI C1-C4 QUE PUEDE SER OPCIONALMENTE SUSTITUIDO POR HALOGENOS; 2) R1 y R2 SON HIDROGENO o ALQUILO C1-C4; 3) X ES S, SO, SO2; 4) Z ES METILENO o ETILENO; DE PREFERENCIA: R1 y R2 SON HIDROGENOS; X ES AZUFRE; A ES 4-FLUORO; B ES HIDROGENO; Z ES ETILENO; DICHO COMPUESTO INHIBE LA ENZIMA LIPOXIGENASA, RESPONSABLE DE LA SINTESIS DE LEUCOTRIENOS, Y PUEDE SER UTIL EN EL TRATAMIENTO DE ENFERMEDADES INFLAMATORIAS, ALERGICAS Y CARDIOVASCULARES
PE1994256818A 1993-12-22 1994-12-12 Feniltiofenil cicloalquenil hidroxiurea PE36395A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP34561893 1993-12-22

Publications (1)

Publication Number Publication Date
PE36395A1 true PE36395A1 (es) 1995-11-07

Family

ID=18377822

Family Applications (1)

Application Number Title Priority Date Filing Date
PE1994256818A PE36395A1 (es) 1993-12-22 1994-12-12 Feniltiofenil cicloalquenil hidroxiurea

Country Status (9)

Country Link
EP (1) EP0736006A1 (es)
JP (1) JP2756732B2 (es)
AU (1) AU1120795A (es)
CA (1) CA2178833A1 (es)
CO (1) CO4230016A1 (es)
FI (1) FI946007A7 (es)
IL (1) IL111994A0 (es)
PE (1) PE36395A1 (es)
WO (1) WO1995017379A1 (es)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3007138B2 (ja) * 1990-11-27 2000-02-07 ファイザー製薬株式会社 新規なヒドロキサム酸とｎ―ヒドロキシ尿素誘導体およびそれらの組成物
US5283361A (en) * 1991-04-23 1994-02-01 Eli Lilly And Company N-hydroxy-N-[3-[2-(halophenylthio)phenyl]prop-2-enyl]ureas as lipoxygenase inhibitors
JPH05294921A (ja) * 1992-04-17 1993-11-09 Pfizer Pharmaceut Co Ltd 新規なフェニル置換シクロアルキル尿素誘導体および組成物

Also Published As

Publication number Publication date
FI946007L (fi) 1995-06-23
IL111994A0 (en) 1995-03-15
CA2178833A1 (en) 1995-06-29
EP0736006A1 (en) 1996-10-09
CO4230016A1 (es) 1995-10-19
JPH09503226A (ja) 1997-03-31
FI946007A0 (fi) 1994-12-21
JP2756732B2 (ja) 1998-05-25
AU1120795A (en) 1995-07-10
FI946007A7 (fi) 1995-06-23
WO1995017379A1 (en) 1995-06-29

Similar Documents

Publication Publication Date Title
ES2174989T3 (es) Pirido(3,2-e)pirazinonas con antiasmatica y procedimiento para su preparacion.
IL165809A0 (en) Substituted heterocyclic compounds and pharmaceutical compositions containing the same
ES2148715T3 (es) Mezcla sinergetica de estabilizadores.
IS2892B (is) 3-amínópýrrólídínafleiður sem bólguboðaviðtakastillar
ES2175804T3 (es) Nuevas pirimidin-4-ona y primidin-4-tiona como fungicida.
FI962489A0 (fi) Morfoliini-ja tiomoforfoliinitakykiniinireseptoriantaginisteja
BR9610970A (pt) Uso de compostos composto composição fungicida e processo de combater fungos fitopatogênicos em um local infestado ou passível de ser infestado com os mesmos
ES2122283T3 (es) Inhibicion del crecimiento capilar.
ECSP055813A (es) Quinolin-, isoquinolin- y quinazolin-oxialquilamidas y su uso como fungicidas
BR9815047A (pt) Aditivo de borracha microencapsulado.
UY27127A1 (es) Derivados de la urea como antagonistas de integrin alfa-4
ES2032873T3 (es) Composicion de sulfuracion previa para un catalizador de hidrotratamiento.
BR0313964A (pt) Composto de malononitrilo e emprego deste
BR0000654A (pt) Preparação de composição de borracha vulcanizada com peróxido e artigos tendo ela pelo menos como um dos seus componentes
DK1144365T3 (da) Inhibitorer af alfa4beta1-medieret celleadhæsion
ATE164178T1 (de) Polychloroprengemischzusammensetzung
ES2088410T3 (es) Fungicidas de acrilato.
ES2133582T3 (es) Esteroides heterociclicos de c17 delta16-insaturados utiles como inhibidores de esteroide c17-20 liasa.
ATE406903T1 (de) Zusammensetzung und ihre verwendungszwecke zur bekämpfung von kater
MX9100917A (es) Composicion farmaceutica que comprende compuestos de difenilo
PE36395A1 (es) Feniltiofenil cicloalquenil hidroxiurea
ES2108618B1 (es) Compuestos de trifendioxazina.
PE57194A1 (es) Hidroxiurea de fenoxifenil ciclopentenil
ES2110185T3 (es) Complejos de beta-lactama biciclica/parabeno.
ES2142490T3 (es) Ciclopeptolidos.

Legal Events

Date Code Title Description
FA Abandonment or withdrawal